NYHA classification of III or IV
STEP I: Patients should not have New York Heart Association classification III or IV heart failure or myocardial infarction within the previous 6 months
Congestive heart failure Class III/IV according to the New York Heart Association (NYHA) Functional Classification.
History of or current Class II, III or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system (Appendix B).
Patient with symptomatic, or history of documented congestive heart failure (NY Heart Association functional classification III-IV);
New York Heart Association Classification II, III, or IV
Heart failure of New York Heart Association Classification III or IV ?6 months prior to Day 1
Acute heart failure (class III or IV of the NYHA classification)
Patient with cardiac failure class III or IV of the NYHA classification
History of documented congestive heart failure (New York Heart Association functional classification III-IV);
New York Heart Association classification III or IV heart failure
New York Heart Association classification III or IV heart failure
History of documented congestive heart failure (New York Heart Association functional classification III-IV) within 6 months prior to initiation of screening
New York Heart Association (NYHA) functional classification I-II
Participants with unilateral pleural effusion will be eligible for inclusion if they fulfill the Global Initiative for Obstructive Lung Disease classification of 0-1 level for pulmonary function and New York Heart Association (NYHA) classification class 1 for cardiac function
Patients classified according to the New York Heart Association classification as having class III or IV heart disease.
Class II to IV heart failure as defined by the New York Heart Association functional classification system
NYHA classification of III or IV
In patients with symptoms of congestive heart failure, New York Heart Association (NYHA) classification of grade III or IV
have any other severe, uncontrolled medical condition, including unstable congestive heart failure (Stage III-IV of the New York Heart Association Functional Classification (Appendix III))
Cardiac conditions as follows: patient has a history of congestive heart failure (CHF) class III/IV according to the New York Heart Association (NYHA) Functional Classification or serious cardiac arrhythmias requiring treatment; patient has a cardiac ejection fraction < 50% by either echocardiogram or multi-gated acquisition (MUGA) scan
New York Heart Association (NYHA) classification IIIB or IV heart failure
NYHA classification of III or IV
Has been classified according to the New York Heart Association classification as having class III or IV heart disease
Class 3 or 4 cardiac disease as defined by the New York Heart Association Functional Classification
Class II, III or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system.
Symptomatic congestive heart failure (New York Heart Association classification Il-IV)
class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system;
Class III/IV cardiovascular disability according to the New York Heart Association Classification
Class III/IV cardiovascular disability according to the New York Heart Association classification
Class III/IV cardiovascular disability according to the New York Heart Association Classification
Symptoms of congestive heart failure as defined by the New York Heart Association (NYHA): Functional Classification class III or IV, or medically uncontrolled cardiac rhythm disturbance
Grade 3 or 4 cardiac disease as defined by the New York Heart Association Functional Classification
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infraction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of left ventricular ejection fraction (LVEF) function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
Class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system
Patients with a New York Heart Association classification of III or IV
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infarction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of LVEF function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
NYHA class III or IV functional classification for heart failure.
Patients that have been designated Class III or IV by the New York Heart Association Functional Classification.
Class 3 or 4 cardiac disease as defined by the New York Heart Association Functional Classification
New York Heart Association classification III or IV heart disease
Congestive heart failure (CHF), grade III or IV per New York Heart Association (NYHA) classification
New York Heart Association Functional Classification of Heart Failure: Class III or IV (Appendix 1).
New York Heart Association classification III or IV
New York Heart Association classification III or IV
New York Heart Association classification III or IV
Participants classified according to the New York Heart Association classification as having class III or IV heart disease
New York Heart Association classification III or IV
New York Heart Classification III or IV heart disease (see Appendix G).  Other severe\n             cardiovascular or cardiopulmonary disease, including COPD
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infraction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of LVEF function\r\n* History of or documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
Patients should not have New York Heart Association classification III or IV heart failure
Subject with Class III or IV Congestive Heart Failure as defined by the New York Heart Association (NYHA) functional classification system within the previous 6 months.
New York Heart Association Classification II, III, or IV (see APPENDIX D)
History of documented congestive heart failure (New York Heart Association functional classification III-IV)
Class III/IV cardiovascular disability according to the New York Heart Association Classification
2. Class III or IV heart failure as defined by the New York Heart Association functional classification system up to 6 months before Cycle 1, Day 1.
Has any other severe, uncontrolled medical condition, including unstable congestive heart failure (Stage III-IV of the New York Heart Association Functional Classification) or has a known or suspected allergy to the study drug or any study drug component.
New York Heart Association classification III or IV heart failure
Grade 3 or 4 cardiac disease as defined by the New York Heart Association Functional Classification
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infraction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of left ventricular ejection fraction (LVEF) function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
History of documented congestive heart failure (New York Heart Association functional classification III-IV)
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infraction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of LVEF function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
Patients with class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system\r\n* Abnormal cardiac valve morphology (subjects with minimal abnormalities, can be entered on study with approval)
Evidence of current Class II, III, or IV heart failure as defined by the New York Heart Association [NYHA, 1994] functional classification system at the time of transition to this study.
History of cardiac dysfunction including any one of the following:\r\n* Myocardial infarction documented by elevated cardiac enzymes or persistent regional wall abnormalities on assessment of left ventricle (LV) function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
Class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system at the time of transition to this study
Uncontrolled arrhythmias; any Class 3-4 cardiac diseases as defined by the New York Heart Association (NYHA) functional classification
Has decompensated congestive heart failure as defined by New York Heart Association (NYHA) functional classification III or IV
Severe cardiovascular disease; New York Heart Association (NYHA) functional classification >= 2
Patient has a history of cardiac dysfunction including any of the following:\r\n* Myocardial infraction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of LVEF function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
Congestive heart failure ? Class 3 based on New York Heart Association Functional Classification
Grade 3 or 4 cardiac disease as defined by the New York Heart Association Functional Classification
New York Heart Association Classification III or IV
History of, or current, documented congestive heart failure (New York Heart Association functional classification III - IV), documented cardiomyopathy.
New York Heart Association classification III or IV congestive heart failure
History of any clinically significant cardiovascular disorder (i.e., symptoms above Class II per New York Heart Association [NYHA] Functional Classification);
New York Heart Association Classification III or IV
New York Heart Association Classification II, III, or IV
New York Heart Association Classification III or IV (see Appendix F)
A New York Heart Association (NYHA) classification of IV.
Class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system
New York Heart Association Classification III or IV (see Appendix E)
New York Heart Association classification III or IV
New York Heart Association (NYHA) classification III or IV heart failure (see Appendix G) despite medical management
History of cardiac dysfunction including any of the following:\r\n* Myocardial infarction within the last 6 months, documented by persistent elevated cardiac enzymes or persistent regional wall abnormalities on assessment of LVEF function\r\n* History of documented congestive heart failure (New York Heart Association functional classification III-IV)\r\n* Documented cardiomyopathy
New York Heart Association (NYHA) classification III or IV congestive heart failure
Class II, III, or IV heart failure as defined by the New York Heart Association functional classification system.
New York Heart Association (NYHA) classification III or IV heart disease
Has Class III or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system.
New York Heart Association (NYHA) classification I or II
New York Heart Association Classification III or IV heart
No current New York Heart Association classification II, III, or IV congestive heart failure
New York Heart Association classification III or IV heart failure
Patient has congestive heart failure Class III/IV according to the New York Heart Association (NYHA) Functional Classification
Class II to IV heart failure as defined by the New York Heart Association functional classification system
Congestive heart failure (New York Heart Association functional classification III-IV)
Patient with known Class III/IV congestive heart failure according to the New York Heart Association classification
History of congestive heart failure (CHF) Class III/IV according to the New York Heart Association (NYHA) Functional Classification or serious cardiac arrhythmias requiring treatment.
History of documented congestive heart failure (New York Heart Association functional classification III-IV).