The patient has received any investigational therapy within 4 weeks of enrollment Use of any investigational drugs, biologics, or devices within 30 days prior or during the study treatment. Use of other investigational drugs at the time of screening or within the last 30 days. Any investigational agents or drugs from a previous clinical study within 28 days Use of other investigational drugs within 28 days prior to study drug administration Investigational Drugs: Subjects who have received another investigational drug within the last 14 days are excluded from participation. Other investigational drugs or investigational therapy if the patient is currently taking those drugs/therapy, or if they have received the drugs/therapy within 1 month. Treatment with any investigational compound within 30 days prior to the first dose of study drugs Subjects taking other investigational drugs or drugs of abuse within 30 days of entry into this study. Patients receiving other investigational immunotherapy or anti-myeloma drugs within 14 days before enrollment. Receipt of an investigational agent within 28 days (or 56 days for an antibody-based therapy) before the first planned dose of study drugs Within 14 days of the first dose of the study drugs: Platelets >= 75,000/L. Patient has used any investigational drugs, biologics (vaccines, antibodies), or devices within 30 days prior to study treatment or has plans to use any of these during the course of the study Patient is receiving other investigational drugs Have received other investigational drugs within 30 days of enrollment. Participated in a previous clinical trial or used any investigational drugs, biologics, or devices within 90 days prior to study treatment or plans to use any of these during the course of the study. Received any investigational drugs within the 14 days prior to CIML NK cell infusion date Received investigational drugs within the 14 days before 1st dose of study drug Investigational drugs: subjects must not have received an investigational drug within 4 weeks Patient has received other investigational drugs with 14 days before enrollment Received any investigational drugs within the 14 days prior to the first day of transplant conditioning Patients who have received other investigational drugs within 14 days prior to screening Receipt of an investigational agent within 28 days (or 60 days for an antibody-based therapy) before the first planned dose of study drugs Exposure to other investigational drugs within 4 weeks before enrollment Patients who are receiving other investigational drugs 14 or fewer days before enrollment Have received other investigational drugs within 14 days prior to enrollment Treatment with any investigational compound within 30 days prior to the first dose of study drugs Patient has received other investigational drugs with 14 days before enrollment Use of any investigational drugs within 30 days prior to dosing Patients who have received other investigational drugs within 28 days of Viralym-A infusion. Patient has received other investigational drugs within 14 days before enrollment Investigational Drugs: Subjects who have received another investigational drug within the last 14 days are excluded from participation. Treatment with other investigational drugs within 6 months of study entry Patient has received other investigational drugs within 4 weeks before enrollment Received any investigational drugs within the 14 days prior to the first dose of fludarabine Exposure to other investigational drugs within 2 weeks before enrollment Patient has received other investigational drugs within 3 weeks before study registration Used any investigational drugs, biologics, or devices within 30 days prior to study treatment or plans to use any of these during the course of the study. Subjects who have received any investigational drugs or devices within 4 weeks before the first day of study treatment (C1D1). Received any investigational drugs within the 14 days before 1st dose of fludarabine Use of other investigational drugs Have received either of the study drugs Participants who are receiving, or have received, any other investigational drugs or devices within the 2 weeks prior to the first dose of study medications Patients who have received hepatotoxic drugs less than 7 days prior to enrollment Received investigational drugs within the 14 days of study registration Use of other investigational drugs within 28 days preceding the first dose of trametinib and during the study Concomitant use of any other investigational drugs Concurrent treatment with other investigational drugs. Patient has received other investigational drugs with 14 days before treatment of treatment with bortezomib + rituximab Used any investigational drugs, biologics, or devices within 30 days prior to study treatment or plans to use any of these during the course of the study. Patient has received other investigational drugs with 14 days before enrollment Currently receiving or has received any investigational drugs within the 14 days prior to the first dose of study drug (day -7) Subjects who have received investigational drugs =< 4 weeks prior to registration Patients on other investigational drugs while on study will be excluded Receipt of an investigational agent within 28 days (or 56 days for an antibody-based therapy) before the first planned dose of study drugs Patient has used any investigational drugs, biologics, or devices within 30 days prior to study treatment or plans to use any of these during the course of the study. Subject has received other investigational drugs within 14 days prior to first dose of study drug. Other investigational drugs within 4 weeks prior to enrollment, unless cleared by the Principal Investigator Use of other investigational drugs within 28 days preceding the first dose of vemurafenib during this study Investigational drugs: subjects must not have received an investigational drug within 4 weeks Any investigational agents or study drugs from a previous clinical study within 30 days of the first dose of study treatment; Prior use of investigational drugs =< 14 days prior to registration Patient has received other investigational drugs with 14 days before enrollment Patient has received other investigational drugs with 14 days before enrollment Concomitant use of any other investigational drugs Receipt of an investigational agent within 30 days (or 60 days for an antibody-based therapy) before the first planned dose of study drugs Taking other investigational drugs Concomitant use of any other investigational drugs Concurrent use of other investigational agents and patients who have received investigational drugs =< 4 weeks prior to enrollment Patient has received other investigational drugs within 3 weeks before study registration Received investigational drugs within the 14 days before enrollment Received any investigational drugs within the 14 days before 1st dose of fludarabine Patient has received other investigational drugs within 14 days prior to enrollment Patient has received other investigational drugs with 14 days before enrollment Patient has received other investigational drugs with 14 days before enrollment Patient has received other investigational drugs with 14 days before enrollment. Patient has not received other investigational drugs with 14 days before enrollment Receipt of investigational drugs within 14 days before D1 of alisertib Use of any investigational drugs, biologics, or devices within 28 days prior to study enrollment Subjects receiving concomitant treatment with radiotherapy or other investigational drugs Concomitant use of any other investigational drugs Patient has received other investigational drugs or chemotherapy within 21 days or approved anti-myeloma therapy within 14 days. Patient has received other investigational drugs with 14 days before enrollment Patient has received other investigational drugs within 1 week before enrollment. Patients who have received other investigational drugs within 28 days of Viralym-C infusion Use of other investigational drugs within 28 days preceding the first dose of vemurafenib on this study. Use of other investigational drugs Have taken any of the following drugs within 7 days prior to Study Day 1: Patient has received other investigational drugs with 14 days before enrollment Patient has received other investigational drugs with 14 days before enrollment Use of anti-cancer treatment (including investigational drugs) within 28 days Patients receiving concurrent investigational drugs Patient has received other investigational drugs within 14 days of treatment initiation Investigative drugs within 21 days Concurrent investigational drugs Patient has received other investigational drugs within 14 days before enrollment or who have not recovered from side effects of those therapies Any treatment with investigational drugs within 30 days before the start of the study Have received other investigational drugs within 28 days prior to enrollment Other investigational drugs within 4 weeks prior to enrollment, unless cleared by the principal investigator Concurrent participation in another study involving investigational drugs or investigational medical devices Patient has used any investigational drugs, biologics, or devices within 14 days prior to study treatment or plans to use any of these during the course of the study Currently receiving or has received any investigational drugs within the 14 days prior to the first dose of the conditioning regimen Not receiving any other investigational agents (i.e., unlabeled drugs or drugs under an investigational new drug [IND] for initial efficacy investigations) Not receiving any other investigational agents (i.e., unlabeled drugs or drugs under an investigational new drug (IND) for initial efficacy investigations Has received investigational drugs suspected to cause peripheral neuropathy; no concurrent investigational drugs may be used Investigational drugs: must not be receiving other investigational (from other studies) drugs at time of enrollment and must not be planning to take other investigational drugs during DLT period Other investigational drugs