Allergy to lidocaine, fentanyl, midazolam, or propofol (may be used during tumor biopsy or injection) Patient has a history of hypersensitivity to fentanyl or opioids Patients who are allergic to or not tolerant of EMLA cream, propofol, or fentanyl will be excluded History of allergy to fentanyl Allergy to fentanyl History of allergy to fentanyl History of allergy to fentanyl All patients with transdermal patches (e.g.; fentanyl, Lidoderm, scopolamine, etc)