Subjects with any coexisting medical or psychiatric condition which, in the opinion of the investigator likely to interfere with study procedures and/or results Concurrent medical condition or disease (e.g., autoimmune disease, active systemic infection) that is likely to interfere with study procedures or results, or that in the opinion of the investigator would constitute a hazard for participating in the study Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results Subject has any concurrent medical condition or disease (eg, active systemic infection, laboratory abnormalities) that is likely to interfere with study procedures or results, or that in the opinion of the investigator would constitute a hazard for participating in this study Any coexisting medical condition that in the judgment of the treating physician is likely to interfere with study procedures or results Any coexisting medical condition that in the judgment of the treating physician is likely to interfere with study procedures or results including uncontrolled severe infections, as well as uncontrolled cardiac disease, or other organ dysfunction; patients with history of tuberculosis, human immunodeficiency virus (HIV) or hepatitis B and C are excluded Subject has any concurrent medical condition or disease (e.g., active systemic infection) that is likely to interfere with study procedures or results, or that in the opinion of the investigator would constitute a hazard for participating in this study No serious uncontrolled coexisting medical condition Any coexisting medical condition precluding full compliance with the study Any concurrent medical or psychiatric condition or disease that is likely to interfere with the study procedures or results, or that in the opinion of the investigator, would constitute a hazard for participating in this study Any concurrent medical or psychiatric condition or disease (eg, autoimmune disease, active systemic disease, myelodysplasia) that is likely to interfere with the study procedures or results, or that in the opinion of the investigator, would constitute a hazard for participating in this study Has any concurrent medical condition or disease (eg, active systemic infection) that is likely to interfere with study procedures Diagnosis of a coexisting medical condition which limits life expectancy to < 2 years Participant has any concurrent medical or psychiatric condition or disease (example active systemic infection, uncontrolled diabetes, acute diffuse infiltrative pulmonary disease) that is likely to interfere with the study procedures or results, or that in the opinion of the investigator, would constitute a hazard for participating in this study Patients must not have any coexisting medical condition that is likely to interfere with study procedures or results, and must be reasonable candidates for intensive chemotherapy, in the opinion of their treating physicians Medical or psychiatric condition or disease (for example, active systemic disease, uncontrolled diabetes) that is likely to interfere with the study procedures or results, or that in the opinion of the investigator, would constitute a hazard for participating in this study Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results Participants with any co-existing medical or psychiatric condition that is likely to interfere with study procedures and/or results Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results Subjects with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results