Able and willing to give informed consent Patients must be able to give adequate informed consent Able to give informed consent TREATMENT: Patient able to give informed consent Patients must be able to give informed consent Patients who are able to give informed consent Willing and able to give informed consent Able to give informed consent Willing and able to give informed consent Donors must be able to give informed consent Able to give informed consent Able to give informed consent Subjects must be able to give informed consent Be able to give informed consent Able to give informed consent Patient able to give informed consent Be able to give informed consent TREATMENT: Patient able to give informed consent Be able and willing to give informed consent Patients should be willing and able to give informed consent Patients are willing and able to give informed consent (Phase II only) DONOR: Able to give informed consent Willing and able to give informed consent Able and willing to give informed consent. Able to give informed consent Able to give informed consent patients who are able to give informed consent Able to give informed consent Able to give informed consent Willing and able to give informed consent Able and willing to give informed consent. Able and willing to give informed consent. Able to give informed consent. Able to give informed consent Willing and able to give informed consent. Willing and able to give informed consent. Willing and able to give informed consent Patients must be able to give informed consent Patients must be able to give informed consent Able to give informed consent Willing and able to give informed consent and adhere to protocol therapy Willing and able to give informed consent Subjects must be able to give informed consent Able to give informed consent ELIGIBILITY FOR ENROLLMENT/SCREENING (ARMS 1 AND 2): Patients must be able to give informed consent Willing and able to give informed consent Willing and able to give informed consent Able to give informed consent Able to participate in the informed consent process Patients must be able to give informed consent Able to give informed consent. Be able to give informed consent Able to give informed consent Willing and able to give informed consent Patient must be able to give informed consent Patients must be able to render informed consent and must consent to participate in the trial Able to give informed consent Able to give consent Able to give informed consent PARTNER: Able to consent to the study Able and willing to give informed consent Able and willing to give informed consent Able to give informed consent Able to give informed consent Able to give informed consent Are able to give consent Participants are able to give consent Participants are eligible if they are able to give consent Are eligible if they are able to give consent Patients and caregivers must both be able to give informed consent Able to give informed consent Subjects are able to give informed consent Able to give informed consent Able to give informed consent Able to give informed consent Able to give informed consent Able to give consent Able to consent for the study All subjects must be able to give informed consent Patients/subjects able to give informed consent Patient is able to give informed consent for this study Subject is able to give informed consent for this study Able to give informed consent Patient must be able and willing to give informed consent Able to give informed consent Able to give consent Women who are not able to give consent Willing and able to give informed consent The patient must be able to give informed consent