Creatinine =< 2.0 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min using the lean body mass formula only
Creatinine =< upper limit of normal (ULN) or calculated creatinine clearance >= 60 mL/min
Creatinine =< institutional upper limit normal (ULN), CTCAE v 3.0 grade 0; NOTE: if creatinine > ULN, creatinine clearance must be > 50 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) mg/dL OR calculated (calc.) creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 40 mL/min, within 4 weeks of randomization
Creatinine =< 1.5 times institutional upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min
Adequate renal function defined as creatinine less than or equal to 1.5 X ULN (upper limit of normal) or calculated creatinine clearance greater than or equal to 40 mL/min per the Cockcroft and Gault formula with creatinine levels greater than 1.5 X ULN
creatinine clearance ?60 mL/min/1.73 m2 for subjects with serum creatinine levels >1.5 × higher than ULN.
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
Measured within 28 days prior to registration: serum or plasma creatinine =< 1.5 x institutional upper limit of normal (ULN) OR creatinine clearance >= 51 mL/min/1.73 m^2 for participants
Creatinine > 1.5 times ULN concurrent with creatinine clearance < 50 ml/min; confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Serum creatinine =< 1.5 x institution's upper limit of normal (ULN), or creatinine clearance >= 30 ml/min (according to Cockroft-Gault formula, or local institutional standard method)
Creatinine =< 1.5 x the institutional upper limit of normal (ULN), or 24-hr clearance >= 50 mL/min, within 14 days of registration
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 50 mL/min
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Serum creatinine or creatinine clearance =< institutional upper limit or >= 60 mL/min creatinine clearance for patients with serum creatinine > institutional upper limit
Serum creatinine =< 1.5 x upper limit of normal or calculated creatinine clearance >= 60 mL/min using Cockcroft-Gault equation for patients with creatinine levels > 1.5 x institutional upper limit of normal (ULN)
Serum creatinine =< 1.5 x institutional upper limit of normal (ULN) OR calculated creatinine clearance >= 50 mL/min for subjects with creatinine levels > 1.5 x institutional ULN within 28 days of treatment initiation and must be independent of hematopoietic growth factor support
Creatinine clearance < 1.5 x institutional ULN
Serum creatinine < 2.0 x ULN or creatinine clearance > 30 cc/min performed within 30 days prior to the date of registration
Creatinine within the institution's laboratory upper limit of normal (ULN) or calculated creatinine clearance >50 ml/min
Creatinine > 1.5 times the ULN concurrent with creatinine clearance < 50 mL/min (measured or calculated by the Cockcroft - Gault equation); confirmation of creatinine clearance is only required when creatinine is > 1.5 times the ULN.
Patient may not have severe renal disease (creatinine greater than 3 times normal for age OR creatinine clearance < 50 ml/m^2/1.73 m^2)
Serum creatinine ?1.5 × institutional upper limit of normal (ULN) or calculated creatinine clearance >30 mL/min.
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 30 mL/min for subject with creatinine levels > 1.5 x institutional ULN
Creatinine =< 1.5 x upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN (obtained =< 14 days prior to registration)
Either creatinine < 1.5 x institutional upper limit of normal (ULN) or creatinine clearance > 60 mL/min as calculated by institution’s standard formula
Creatinine < 1.5 x ULN OR creatinine clearance > 50 mL/min for subject with creatinine levels > 1.5 x ULN
COHORT 1: HORMONE RECEPTOR POSITIVE BREAST CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
COHORT 2: TRIPLE NEGATIVE BREAST CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
COHORT 3: ENDOMETRIAL CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min for subject with creatinine ? 1.5 x institutional ULN obtained =< 14 days prior to registration
Creatinine OR calculated creatinine clearance =< 1.5 x upper limit of normal (ULN) OR >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN. Creatinine clearance should be calculated per institutional standard.
Serum creatinine < 2 x upper limit of normal (ULN) or estimated creatinine clearance > 30 ml/min as calculated using the method standard for the institution
Obtained =< 14 days prior to registration: Creatinine =< 1.5 X upper limit of normal (ULN)\r\n* NOTE: measured or calculated (per institutional standard) creatinine clearance is acceptable >= 60 mL/min for subject with creatinine levels > 1.5 X institutional ULN
Creatinine =< 2.0 x the institutional upper limit of normal (ULN) OR creatinine clearance > 30 ml/min within 14 days of cycle 1 day 1
Cockcroft calculated creatinine clearance of >= 45 ml/min or 1.5 x the upper limit of normal (ULN)
Serum creatinine =< 1.5 x age-adjusted upper limit of normal (ULN) or calculated creatinine clearance (Cockcroft and Gault) > 30 mL/min/1.73 m^2
Creatinine =< 1.5 ULN OR creatinine clearance >= 60 Ml/min/1.73 m^2 for patients with creatinine levels above ULN calculated using Calvert formula
Serum creatinine =< 2 x upper limit of normal (ULN) or estimated creatinine clearance >= 15 mL/min as calculated using the method standard for the institution
Serum creatinine >= 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance =< 30 mL/min for patients with creatinine levels > 1.5 x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard
Serum creatinine =< 1.5 x institution’s upper limit of normal (ULN), or creatinine clearance >= 60 ml/min
Serum creatinine > 1.5 x upper limit of normal (ULN) or creatinine clearance < 40 mL/min (measured or calculated by Cockroft-Gault formula)
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min for subject with creatinine ? 1.5 x institutional ULN obtained =< 14 days prior to registration
Creatinine level =< upper limit of normal (ULN): if creatinine > ULN, creatinine clearance must be > 60 ml/min
Serum creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min/1.73 m^2)
Adequate renal function defined as: • Serum creatinine ? 1.5 x ULN (upper normal limit) or calculated creatinine clearance (determined by MDRD) > 50 mL/min/1.73m2.
Serum creatinine =< upper limit of normal (ULN) for the lab or a calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 50 mL/min for patient with creatinine levels > 1.5 x institutional ULN
Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1.73 m^2
Creatinine less than or equal to 1.5 x upper limit of normal (ULN) with calculated creatinine clearance greater than 30 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 60 mL/min for subjects with creatinine levels > 1.5 x ULN within 14 days of treatment initiation
Creatinine =< 2.0 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above 2.0 x ULN
Serum creatinine < 2.0 times the upper limit of normal (ULN) (or a calculated creatinine clearance >= 60 mL/min)
Creatinine > 1.5 times ULN concurrent with creatinine clearance < 30 ml/min (measured or calculated by Cockcroft and Gault equation); confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Creatinine clearance >= 40 ml/min or serum creatinine =< 2.5 x upper limit of normal (ULN)
Serum creatinine >= ULN and/or calculated or measured creatinine clearance < 75% lower limit of normal (LLN)
Creatinine =< 2.0 x upper limit normal (ULN) or measured creatinine clearance (CrCl) of >= 50ml/m^2/1.73 m^2
Creatinine =< 1.5 x the upper limit of normal (ULN) OR \r\n* Estimated creatinine clearance of > 50 ml/min\r\n* Patients with renal dysfunction deemed to be the result of disease will be considered eligible
Creatinine clearance >= 60 mL/min/1.73m^2 for patients with creatinine >= 1.5 x upper limit of normal
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
CAPMATINIB INCLUSION CRITERIA: Creatinine OR creatinine clearance within normal limits > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
REGORAFENIB INCLUSION CRITERIA: Creatinine OR creatinine clearance =< 1.5 x ULN; > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
ENTRECTINIB INCLUSION CRITERIA: Creatinine OR creatinine clearance within normal limits; > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
Serum creatinine =< 1.25 times upper limit of normal or calculated creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 X ULN OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 X institutional ULN
Calculated creatinine clearance ? 60 mL/min /1.73 m2 for subjects with serum creatinine levels > 1.5 x institutional ULN
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= 60 mL/min
Serum creatinine >1.5 x ULN and/or measured or calculated creatinine clearance <75% LLN
Biochemistry: Total bilirubin* ? institutional upper limit of normal Alkaline phosphatase ? 2.5 x institutional upper limit of normal AST(SGOT) and ALT(SGPT) ? 2.5 x institutional upper limit of normal Creatinine Clearance ? 40 ml/min * excluding Gilbert's syndrome Creatinine clearance to be measured directly by 24 hour urine sampling or as calculated by Cockcroft Formula: Females: GFR = 1.04 x (140-age) x weight in kg serum creatinine in ?mol/L Males: GFR = 1.23 x (140-age) x weight in kg serum creatinine in ?mol/L
Serum creatinine < 1.5 times upper limit of normal range (ULN) or creatinine clearance >= 40 ml/min
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance of >= 50ml/min
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 x institutional ULN
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard
Serum creatinine =< 1.5 X upper limit of normal (ULN) or creatinine clearance > 50 mL/min
Serum creatinine > 1.5 times ULN concurrent with creatinine clearance < 50 mL/min (measured or calculated by Cockcroft and Gault equation)—confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Adequate renal function (creatinine =< 1.25 upper limit of institutional normal [ULIN] or calculated creatinine clearance > 50 ml/min)
Serum creatinine =< 2 x the institutional ULN and measured or estimated creatinine clearance > 60 cc/min
The patient must have a corrected creatinine clearance >= 50% of normal
Serum creatinine =< 1.5 x institutional upper limit normal (ULN) and calculated creatinine clearance of >= 60mL/min
Creatinine ?1.5 times the upper limit of normal (ULN) and/or creatinine clearance ?60 mL/min
REGISTRATION TO TREATMENT (STEP 1): Serum creatinine =< 1.5 X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= 60 mL/min for patient with creatinine levels > 1.5 X ULN, within 14 days prior to first dose of pembrolizumab
REGISTRATION TO TREATMENT (STEP 2): Serum creatinine =< 1.5 X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= 60 mL/min for patient with creatinine levels > 1.5 X ULN, within 14 days prior to first dose of pembrolizumab
Creatinine =< 1.5 x upper limit of normal (ULN) OR >= 60 mL/min
Within 10 days of treatment initiation: If serum creatinine concentration >= 1.5 x upper limit of normal (ULN), then estimated creatinine clearance must be >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN
Creatinine or measured/calculated creatinine clearance (as calculated by institutional standard) =< 1.5 X institutional upper limit of normal (ULN) OR >= 60 mL/min for subjects with creatinine levels > 1.5 x institutional ULN
Serum creatinine value < upper limit of normal (ULN) or creatinine clearance of >= 60 mL/min according to Cockgroft?Gault formula
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine OR =< 1.5 mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= 60 mL/min
Patients must have a serum creatinine limit of =< 1.5 ULN or creatinine clearance of >= 60 ml/min measured within 14 days of registration
Creatinine < 1.5 x ULN OR creatinine clearance measured >= 60 mL/minute for patients with creatinine levels >= 1.5 x upper limit of normal
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance > 45 mL/min
Serum creatinine =< 1.5 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% LLN (lower limit of normal)
Creatinine =< 1.5 times the upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Creatinine =< institutional upper limit normal (ULN); note: if creatinine > ULN, creatinine clearance must be > 50 mL/min
Creatinine =< 1.5 X ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x ULN
PHASE II: Creatinine =< 1.5 X ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x ULN
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 2.0 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 30 mL/min obtained within 28 days prior to registration
Serum creatinine =< ULN within 14 days prior to registration OR calculated creatinine clearance > 50 ml/min; the serum creatinine value used in the calculation must have been obtained within 14 days prior to registration
Creatinine =< 1.5 x ULN OR calculated or measured creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine above institutional normal
Serum creatinine =< 1.5 X upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 X institutional ULN
Creatinine =< 1.5 mg/dL x upper limits of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine > 1.5 x the upper limit of normal; patients with creatinine > 1.5 x the upper limit of normal who have creatinine clearance >= 60 cc/min (calculated using the Cockcroft and Gault equation) are eligible
Serum creatinine =< 1.5 x upper limit of normal (ULN) for the lab, calculated creatinine clearance >= 60 mL/min or 24-hour creatinine clearance >= 50 mL/min
Serum creatinine ?1.5 times institutional ULN or calculated creatinine clearance >30 mL/min;
Serum creatinine =< 1.5 x institutional upper limit of normal concurrent with creatinine clearance >= 50 mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > 1.5 x upper limit of normal (ULN), within 14 days of study registration
Within 72 h of initiating study treatment: Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 x ULN (Cockcroft and Gault)
Creatinine =< ULN or a calculated creatinine clearance of >= 45 ml/min if creatinine is greater than the ULN
Serum creatinine performed within 4 weeks prior to study entry must be less than or equal to 1.25 x ULN or estimated creatinine clearance less than 60 mL/min (as calculated using the method standard for the institutions).
Patients must have adequate renal function, defined as serum creatinine ? 1.5 x ULN or creatinine clearance (calculated) ? 60 mL/min/1.73 m2 for patients with creatinine > 1.5 x ULN.
Creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance >= 30 mL/min (Cockcroft-Gault calculation)
Creatinine <1.5 X upper limit of normal or estimated plasma creatinine clearance of ?40 mL/min
At least 4 weeks (28 days) prior to registration: Serum creatinine =< 1.5 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% LLN (lower limit of normal)
Serum creatinine ? 1.5 × age-adjusted upper limit of normal (ULN) OR calculated creatinine clearance > 30 mL/min
Serum creatinine =< upper limit of normal (ULN) or creatinine clearance (either estimated or calculated) >= 60 mL/min/1.73 m for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 × the institutional ULN; if creatinine is above the ULN, the patient's measured or calculated creatinine clearance (CrCl) must be >= 50 mL/min
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73m^2 for patients with creatinine >= 1.5 x upper limit of normal
Serum creatinine =< 1.5 x upper limit of normal OR calculated creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance >= 40 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 x the upper limit of normal or creatinine clearance >= 60 mL/min (measured or calculated)
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
Serum creatinine clearance =< 1.5 x ULN or >= 60 mL/minute for subjects with creatinine levels > 1.5 x the institutional upper limit of normal (ULN)
Serum creatinine ? 1.5 × ULN according to institutional standards or creatinine clearance ? 50 mL/min
Serum creatinine ?1.5 x upper limit of normal (ULN) or a calculated creatinine clearance >60 mL/min,
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 2 x the institutional ULN and measured or estimated creatinine clearance >= 50 cc/min
Serum creatinine <1.5 x upper limit of normal (ULN) or estimated creatinine clearance 60 mL/min (as calculated using the standard method of the institution);
Patient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.
Adequate renal function defined as serum creatinine ? 1.5x upper limit of normal (ULN) for age. If the serum creatinine is above these values, the calculated creatinine clearance or radioisotope GFR must be ? 70 mL/min/1.73m2.
Creatinine =< 1.5 x upper limit of normal (ULN); either lab result or calculated clearance
Serum creatinine > 1.5 x ULN and/or measured or calculated creatinine clearance < 75% LLN (lower limit of normal) Bone marrow function:
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 mL/min (please use institutional formula)
Serum creatinine < 1.5 x ULN or creatinine clearance ? 60 mL/min as measured by institutional standards
Calculated creatinine clearance (CrCl) of greater than or equal to 50 or serum creatinine less than 2 x ULN; even if organ function abnormalities are considered due to tumor, the upper limit for creatinine is less than or equal to 2 mg/dL
Acceptable renal function: • Serum creatinine ? 1.5 times the ULN, or calculated creatinine clearance ? 60 mL/min/1.73 m2 for patients with creatinine levels above 1.5 times the institutional normal
Creatinine > 2.0 times upper normal limit and creatinine clearance < 30 ml/min/m^2; patients with creatinine > 2 times upper limit of normal will have creatinine clearance estimated; at the discretion of treating physician, creatinine clearance can be measured and that value can be used instead of calculated creatinine clearance
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN), or, calculated creatinine clearance (CrCl) >= 50 mL/min
Creatinine =< 1.5 x upper limits of normal (ULN); if creatinine (Cr.) > 1.5 x ULN, then calculated creatinine clearance > 40 cc/min
Serum Creatinine < 1.5 x ULN (upper limit of normal) or estimated creatinine clearance ? 60 mL/min, as calculated using method standard for the institution (Appendix 2).
Patient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.
Creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance >= 60 ml for patients with creatinine levels 1.5 times above institutional ULN (calculated based on age, weight and sex)
Creatinine < 1.5 times the upper limit of normal (ULN) or creatinine clearance > 40 mL/min (as measured or calculated by Cockroft-Gault formula)
Serum creatinine ? 1.5 x upper limit of normal (ULN) or calculated creatinine clearance > 60 mL/min if the serum creatinine is > 1.5 x ULN
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Creatinine < 2.0 x upper limit of normal and/or a creatinine clearance >= 60 ml/min
Serum creatinine > 1.5 x upper limit of normal (ULN); if creatinine 1.0-1.5 x ULN, creatinine clearance, calculated according to Cockcroft-Gault formula, < 60 ml/min will exclude the patient
Creatinine =< 1.5 x ULN OR calculated or measured creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine above institutional normal
Patients must have adequate renal function, defined as serum creatinine <= 1.5 x upper limit of normal (ULN) for the institution or a calculated creatinine clearance [Cockcroft-Gault method] must be >= 60 mL/min/1.73 m^2).
Kidney disease with a calculated creatinine clearance <30% normal value.
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance >= 50 cc/min
Serum creatinine ? 1.5 × upper limit of normal (ULN) or calculated creatinine clearance ? 50 mL/min using Cockcroft-Gault equation for patients with creatinine levels > 1.5× institutional ULN
Serum creatinine ?1.5 x ULN or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels >1.5 x ULN
Serum creatinine less than 1.5 x upper limit of normal (ULN), OR 24-hour creatinine clearance = or 60 mL/min for subject with creatinine levels more than 1.5 x ULN; (Note: creatinine clearance need not be determined if the\r\nbaseline serum creatinine is within normal limits; creatinine clearance should be determined per institutional standard)
Creatinine value of =< 1.5 x upper limit of normal (ULN) or creatinine clearance value of >= 40 mL/min
Creatinine ? 1.5 x upper limit of normal (ULN) of institution's range or Creatinine clearance ? 50%
Serum creatinine < 1.5 x upper limit of normal (ULN) or a calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x institutional upper limit of normal concurrent with creatinine clearance >= 50 mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > 1.5 x upper limit of normal (ULN) (within 14 days of study registration)
Serum creatinine =< 4.0 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% of LLN (lower limit of normal)
Have adequate renal function, defined as serum creatinine levels ?2.0 ULN or calculated creatinine clearance >45 mL/min.