Regular access to a computer with internet service To ensure compliance with the POWER-remote and PatientViewpoint programs, patients must meet the following:\r\n* Prior experience with web forms and feels able to use the POWER-remote web program and PatientViewpoint\r\n* Has or is able to download Internet Explorer 8+, Firefox 3.0+, Safari 4.0+, Chrome 4.0+, and Adobe Flash Player 10\r\n* Familiarity with and access to internet at least 4 days per week\r\n* Use of an email program or willing and able to establish one for this study\r\n* Able to read and write the English language without assistance\r\nNOTE: participants who are unable to receive email or to complete the PatientViewpoint questionnaires for any reason will not be allowed to continue on the study Caregiver: Must demonstrate basic computer literacy skills, defined as at least one-hour per week spent using a computer, and have access to an internet terminal (required for the use of oNCF testing) Subjects with sufficient vascular access to accommodate the RBCx procedure as determined by the medical staff responsible for obtaining intravenous access. Regular access to a smart phone, tablet or computer Have reliable internet access People without internet access Consistent daily access to a smartphone No access to a smart phone or text messaging plan less than 150 messages per month Have access to the internet during the 4-hour online course and at least once per month to participate in post-training virtual meetings, discussion board postings, email, and periodic audio chat conferences Have access to a computer, tablet, or smartphone (iPhone or Android) with built-in camera and microphone Internet access through computer, laptop, tablet, or other mobile device Have regular access (e.g. home or work) to high speed/satellite broadband Internet on desk/laptop or wireless iPad, Android or iPhone throughout the 3 months of the study\r\n* Several iPads with wireless plan will be available to women who are eligible, but do not have computer access Ability to access the internet and watch videos online Do not have access to at least one intervention format PATIENT & PARTNER: Have access to internet connectivity Have access to a phone for contact with health coach Usability Testing and the randomized control trial (RCT): have access to a computer, a smartphone or an i-Pad/tablet equivalent with internet access Access to either wireless internet (WiFi) or cellular service and permission/ability to download the wearable fitness device app on an apple device, android, or computer (or willingness to use a study-provided iPod to allow the data to be uploaded to the study team) History of difficult intravenous access Lack of internet and email access The participant has access to the internet Phase I: Access to the internet Phase II: Access to the internet Eligible patients must have access to a mobile phone with internet and text messaging capabilities Eligible patients must be able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the internet Patients with no regular access to the internet or a mobile phone and those who are unable to fill out forms on the web or navigate websites Access to refrigerator or freezer Patient must have access to the internet through computers or mobile devices (smart phones and tablets) Have access to mobile hot spot, wireless internet, and/or cellular service Have high-speed access to the internet at home or work; this could be broadband, digital subscriber line (DSL), and/or access on a smartphone or tablet via a wireless provider YBCS: Access to an internet connection HCP: Access to an Internet connection DCG: Will be able to access internet (phone, computer, etc.) Has internet access Knowledge of the internet and how to use web-based programs Patients must have regular access to a computer or tablet with internet access TECHNOLOGY REQUIREMENT: Patients willing to provide their own internet access for this study; this will include either a data plan or wireless-fidelity (Wi-Fi) access on the patient’s smart phone for use of the Jawbone App; they will also need internet access (through their smart phone or home computer) for setting up a Self-Generated Health Information Exchange (SGHIx) account; patients are welcome to use the free guest Wi-Fi access within the Duke outpatient clinic area for the purpose of this study SUBJECT: Have regular access to a computer (either personal computer [PC] or Mac with a built-in Universal Serial Bus [USB] port). Inability to access a computer with internet or inability to use a computer with internet provided by the study as indicated by self-report SUPPORT PROVIDER: Inability to access a computer with internet or inability to use a computer with internet provided by the study as indicated by self-report Unreliable phone access Have access to the internet and an active email account Have access to and are able to use the internet at a minimum of once per week Research participants who have no computer and internet access and/or do not use a computer even if one is present in the household Use the internet on a regular basis Has access to a personal computer with internet access Have access to the internet and a computer, tablet, or smart phone, and Patients must have working email address and internet access Access to email and a computer with internet Must have access to either wireless Internet and a phone capable of receiving text messages Patients must have a mobile phone that can send and receive SMS/MMS messages and is internet-enabled Access to a telephone for coaching sessions and access to a computer, smartphone, or tablet for syncing Fitbit devices Access to smartphone device compatible to sync with PAM device Be able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the internet No regular access to the internet and not able to fill out forms on the web, communicate by email and navigate websites Patients have internet access to the web-based program at home or willing to access the web-based program using the computer provided by the researchers at the Cancer Center Access and ability to use a computer for completion of online measures CANCER PATIENT GROUP: Has access to a smartphone or computer with internet capabilities NON-CANCER PATIENT GROUP: Has access to a smartphone or computer with internet capabilities Have access to an International Business Machines (IBM)-compatible or Macintosh personal computer with Internet access (either in home or at a community center) Stage II only: have access to the Internet or a smart phone Access to a telephone, computer (e.g. desktop, laptop, smartphone, tablet), and internet No access to a computer, or compact disc audio player No access to the internet in a private location Have a computer, laptop, smartphone, or tablet with internet access Have access to a mobile phone Be able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the internet Patients with no regular access to the internet or a mobile phone or who are unable to fill out forms on the web or navigate websites Have reliable internet and daily access to computer with audio/speakers Reliable internet access Has access to and is able to operate a computer with internet access Have access to a mobile phone Be able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the internet CAREGIVER: Be able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the internet If participants are unable to access a computer they will be excluded Limited or no access to a touch tone phone Have access to high speed internet Unable to access the internet Have access to a DVD player or computer that can play DVDs Adults with access to the Internet or ability to travel to Washington University to participate in person; despite a recruitment focus in St. Louis, residency is not required for participation Patient must have access to a smart phone with Android 4.3 or later or iOS 7.1 or later or computer (laptop/desktop) with a connection to the internet to create an account and be able to sync the Sqord device (accelerometer) Internet access (daily). Regular access to an internet-enabled device that can be synched with the Fitbit wristband No daily internet access Access to devices that play DVDs Has access to a computer or mobile device with wireless internet Regular access to computer with a reliable internet connection Access to phone PILOTS I, II AND III: Have access to internet Access to smart phone or computer with internet access. Any patient who does not have Internet access Internet access and a compatible device\r\n* If patients do not own a compatible device the study team may loan a device to be returned at the end of the study Access to either a smart phone or computer on a daily basis to sync Fitbit data to the data repository Has email address and internet access to complete online surveys Internet access\r\n* If patients do not own a compatible device the study team will loan a device to be returned at the end of the study Access to smartphone, tablet or computer with capability to utilize symptom-tracking application Must have internet access and a valid email address No access to a computer, smartphone or internet Use internet on average at-least once a week (RCT) Own a cell phone, are able to send and receive text message and access the internet, and