Baseline severe hepatic impairment (Child-Pugh Class B & C) Hepatic impairment Child-Pugh < B7. Patients with moderate or severe liver impairment, as defined by a Child-Pugh class of B or C Baseline moderate and severe hepatic impairment (Child Pugh class B & C) Severe hepatic impairment (Child-Pugh Class C). Subjects with chronic liver disease with hepatic impairment Child-Pugh class B or C Patients with baseline moderate to severe hepatic impairment (Child-Pugh class B and C) Child Pugh class B or greater hepatic dysfunction Baseline moderate or severe hepatic impairment (Child-Pugh class B or C) Patients must NOT have liver disease such as cirrhosis or sever hepatic impairment as defined by Child-Pugh class B or C Child Pugh class C hepatic dysfunction Hepatic cirrhosis or a Child-Pugh score of C (severe hepatic impairment) at the time of randomization. Baseline moderate or severe hepatic impairment (Child Pugh class B & C) Hepatic impairment which is moderate (Child-Pugh B) or severe (Child-Pugh C) Severe hepatic impairment (Child-Pugh class C) Patients with mild (Child-Pugh A) or moderate (Child-Pugh B) hepatic and/or moderate (creatinine clearance [CrCl] 30-50 mL/min) renal impairment Moderate or severe hepatic impairment defined as Child-Pugh class B or C Moderate or severe hepatic impairment, i.e. Child-Pugh class B or C. Severe hepatic impairment (Child-Pugh class C) Severe hepatic impairment (Child-Pugh class C) Severe hepatic impairment (Child-Pugh class C) Patients with Child-Pugh B or C hepatic impairment Hepatic impairment (Child Pugh classes A-C) that is not considered to be the result of leukemic involvement as determined by the PI Moderate and severe hepatic impairment, ie Child-Pugh B or C Patients with severe hepatic impairment (Child-Pugh class C) Patients with severe hepatic impairment (Child-Pugh class C) Severe hepatic impairment (Child-Pugh class C) Moderate or severe hepatic impairment, i.e. Child-Pugh class B or C Severe hepatic impairment (Child-Pugh class C) Moderate or severe hepatic impairment, i.e. Child-Pugh class B or C Moderate or severe hepatic impairment, i.e. Child-Pugh class B or C Moderate and severe hepatic impairment, i.e. Child-Pugh B or C Liver disease such as cirrhosis or severe hepatic impairment (Child-Pugh Class C). Patients with severe hepatic impairment (Child-Pugh class C) Child-Pugh class B or C hepatic impairment No severe hepatic impairment (Child-Pugh class C) or acute liver disease Patients with severe hepatic dysfunction (Child Pugh class C) Moderately impaired hepatic function (Child-Pugh B) or severe hepatic impairment (Child-Pugh C) Severe hepatic impairment (Child-Pugh class C) Severe hepatic disease, defined as a diagnosis of Child-Pugh Class B or C hepatic disease. Patients with severe hepatic impairment (Child-Pugh class C) Moderate or severe hepatic insufficiency Child-Pugh score > 6