Patients with untreated or active hepatitis B or C infection Are untreated. Untreated active HBV Symptomatic untreated strictures Previously untreated Presence of active untreated infection Untreated active infection Untreated active infection Uncontrolled active, untreated, or progressive infection Untreated active major depression Uncontrolled active, untreated, or progressive infection Untreated active infection Untreated active infection Presence of any untreated systemic infection Patients with untreated or uncontrolled neuropsychiatric illness Evidence of untreated infection Presence of active untreated infection Patient has untreated severe hypothyroidism Patients must be untreated with radiation above the clavicles Active untreated infection Patients with known untreated hepatitis C Chronic active untreated hepatitis B or C infection Untreated systemic infection Untreated or uncontrolled 2nd malignancy Hepatitis B or C infection (HBV), or untreated systemic infection Untreated hepatitis B infection The presence of co-existing medical conditions that would limit compliance with study medications, including, but not limited to active infection, active or untreated cardiac or pulmonary disease, or malignancy Patients must be previously untreated UNTREATED PRIMARY: Active untreated infection Active untreated infection Has untreated hypo- or hyperthyroidism; Untreated bladder infection Patients with untreated clinically relevant hypothyroidism Patients with any of the following conditions: untreated gastrointestinal reflux disease; untreated diabetes mellitus; active thrush; active oral infection; active mucositis Patients with any of the following conditions: untreated gastrointestinal reflux disease; untreated diabetes mellitus; active thrush; active oral infection; active mucositis Untreated active infection Untreated; OR