Patient must not have an intercurrent illness likely to interfere with protocol therapy Significant intercurrent illness that will limit the patient's ability to participate in the study or may result in their death over the next 18 months Significant intercurrent illness that will limit the patient's ability to participate in the study Patient has uncontrolled intercurrent illness Concurrent or Intercurrent Illness: Uncontrolled intercurrent illness judged by the treating investigator to preclude treatment with chemotherapy Uncontrolled intercurrent illness including Subjects must have no uncontrolled intercurrent illness Subject has any other active malignancy besides the tumor under study within 3 years prior to Screening. Subject has uncontrolled intercurrent illness Significant intercurrent illness Other uncontrolled intercurrent illness that would limit adherence to study requirements Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic Subjects with serious intercurrent chronic or acute illness, such as cardiac or pulmonary disease, hepatic disease, or other illness considered by the Investigator as high risk for investigational drug treatment Uncontrolled concurrent serious illness Subjects with a history of serious intercurrent chronic or acute illness, such as cardiac or pulmonary disease, hepatic disease, or other illness considered by the investigator as high risk for investigational drug treatment Uncontrolled intercurrent illness Uncontrolled intercurrent illness Significant uncontrolled intercurrent illness that will limit the patient's ability to participate in the study Uncontrolled concurrent serious illness Uncontrolled intercurrent illness Subject has any other active malignancy besides the tumor under study within 3 years prior to Screening. Subject has uncontrolled intercurrent illness. Uncontrolled intercurrent illness including, but not limited to: Other serious intercurrent illness Uncontrolled intercurrent illness No uncontrolled intercurrent illness or infection Uncontrolled intercurrent illness including active infection Uncontrolled significant intercurrent illness that would preclude the patient from study participation per investigator assessment Uncontrolled intercurrent illness including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, need for ventilatory support Uncontrolled intercurrent illness, including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, need for ventilatory support Uncontrolled intercurrent illness including, but not limited to, active infection requiring hospitalization History of uncontrolled intercurrent illness: Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection Severe or uncontrolled intercurrent illness/infection Uncontrolled intercurrent illness. Subjects must have no uncontrolled intercurrent illness Uncontrolled concurrent illness; Uncontrolled intercurrent illness including, but not limited to: Uncontrolled intercurrent illness Uncontrolled intercurrent illness. Uncontrolled intercurrent illness as outlined in protocol Uncontrolled concurrent disease or illness Uncontrolled intercurrent illness. Uncontrolled intercurrent illness, including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, need for ventilatory support. Treatment of pre-existing invasive fungal infections must be completed prior to starting treatment. Uncontrolled intercurrent illness Subjects with serious intercurrent chronic or acute illness, such as cardiac or pulmonary disease, hepatic disease, or other illness considered by the Investigator as high risk for investigational drug treatment Patients who have an uncontrolled intercurrent illness including, but not limited to any of the following, are not eligible Uncontrolled intercurrent illness Uncontrolled intercurrent illness; Uncontrolled intercurrent illness Other serious intercurrent illness The subject has uncontrolled, significant intercurrent or recent illness including, but not limited to, the following conditions: Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection Uncontrolled intercurrent illness Any significant uncontrolled intercurrent systemic illness Concurrent uncontrolled illness not related to cancer, including but not limited to: Uncontrolled intercurrent illness, including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, need for ventilatory support Significant uncontrolled intercurrent illness Uncontrolled intercurrent illness Uncontrolled intercurrent illness, including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, or need for ventilatory support Concurrent uncontrolled illness not related to cancer, including but not limited to: Uncontrolled intercurrent illness Uncontrolled intercurrent illness (i.e., active infection) or concurrent condition that, in the opinion of the Investigator, would interfere with the study endpoints or the patient's ability to participate Uncontrolled intercurrent illness (i.e., active infection ? Grade 2) or concurrent condition that, in the opinion of the Investigator, would interfere with the study endpoints or the subject's ability to participate. Any uncontrolled, intercurrent illness that in the opinion of the Investigator may interfere with study evaluation. Participants with uncontrolled diabetes will be excluded from the study. Uncontrolled intercurrent illness Patients must not have a serious intercurrent illness including, but not limited to: The subject has uncontrolled, significant intercurrent or recent illness including, but not limited to, the following conditions: Uncontrolled intercurrent illness including, but not limited to: Uncontrolled intercurrent illness including, but not limited to, any of the following: Uncontrolled intercurrent illness per protocol Significant intercurrent illness defined as an illness that may result in the subject's death prior to their death from non-squamous NSCLC and/or significantly limit their ability to comply with the requirements of this study Uncontrolled systemic disease or intercurrent illness Significant intercurrent illness that will limit the patient's ability to participate in the study or may result in their death over the next 18 months Serious or uncontrolled intercurrent illness Has a significant uncontrolled intercurrent illness including, but not limited to: Significant intercurrent illness that will limit the patient's ability to participate in the study or may result in their death over the next 18 months Uncontrolled intercurrent illness that would preclude a patient from undergoing surgery Uncontrolled concurrent illness Uncontrolled intercurrent illness. Concurrent or Intercurrent Illness: The subject has uncontrolled, significant intercurrent or recent illness including, but not limited to, the following conditions: Concurrent severe, intercurrent illness. Serious intercurrent chronic or acute illness, such as cardiac disease, hepatic disease, or other illness considered by the investigator as an unwarranted high risk for an investigational product Uncontrolled current illness Subject has uncontrolled intercurrent illness including, but not limited to: Other uncontrolled significant illness. No exclusion requirements due to co-morbid disease or intercurrent illness Uncontrolled serious concurrent illness Serious intercurrent medical illness Uncontrolled intercurrent illness including, but not limited to active infections Uncontrolled intercurrent illness, including but not limited to interstitial lung disease. No requirements due to co-morbid disease or intercurrent illness, as needed Uncontrolled intercurrent illness.