Inability to swallow oral medications Inability to swallow oral medications Inability to take oral medications Inability to swallow medications Inability to tolerate oral medications. Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment. Inability to take oral medications Patients must not have significantly diseased or obstructed gastrointestinal tract, malabsorption, uncontrolled vomiting or diarrhea, or inability to swallow oral medications. Inability to swallow or absorb drug Inability to swallow oral medications. Inability to swallow medications Inability to swallow oral medications Inability or unwillingness to swallow oral medications Significantly diseased or obstructed gastrointestinal tract, malabsorption, uncontrolled vomiting or diarrhea or inability to swallow oral medications Inability to swallow or tolerate oral medication. Inability to swallow oral medications Inability to swallow food or any condition of the upper gastrointestinal tract that precludes administration of oral medications inability to take oral medication inability to take oral medication; Inability to tolerate oral medication Inability or unwilling to swallow study drug Inability to swallow medication Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment Inability to swallow medications Inability to swallow food or any condition of the upper gastrointestinal tract that precludes administration of oral medications Any gastrointestinal tract disease or other medical condition resulting in the inability to take oral medications Inability to swallow intact tablets or inability to take pembrolizumab or cabozantinib Inability to swallow medication Inability to take oral medications on a continuous basis Inability to take medications by mouth Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment. Inability to swallow oral medication Inability to swallow oral medication or inability or unwillingness to comply with the administration requirements related to alisertib Inability to swallow pills or any significant gastrointestinal disease which would preclude the adequate oral absorption of medications Inability to take oral medication Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements or GI procedure that could interfere with the oral absorption or tolerance of treatment Inability to swallow oral medication or inability or unwillingness to comply with the administration requirements related to alisertib Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment. Inability to take oral medications Inability to swallow pills or any significant gastrointestinal diseases, which would preclude adequate absorption of oral medications. PART B: Patients with inability to take oral medications, or, in the investigator’s opinion, gastrointestinal conditions or abnormalities likely to influence the absorption of oral medications Inability to swallow oral medications or any malabsorption condition Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment Inability to swallow or absorb drug Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal (GI) procedure that could interfere with the oral absorption or tolerance of treatment Inability to swallow oral medication, inability or unwillingness to comply with the drug administration requirements, or gastrointestinal condition that could interfere with the oral absorption or tolerance of treatment. Significant malabsorption syndrome or inability to tolerate oral medications Inability to swallow oral medications Inability to take oral medication Inability to swallow pills or any significant gastrointestinal disease which would preclude the adequate oral absorption of medications Clinical conditions affecting the intake and use of oral medications (e.g., inability to swallow, chronic diarrhea, and intestinal obstruction) Inability to tolerate oral medications. Inability to swallow oral medication or inability or unwillingness to comply with the administration requirements related to alisertib Has inability to swallow oral medications or presence of a gastrointestinal disorder (e.g. malabsorption) deemed to jeopardize intestinal absorption of MK-8628 Inability to swallow oral medications or any medical conditions that may affect intestinal absorption of the study agent or inability to comply with oral medication Inability to take oral medications, due to impaired swallowing ability or poor absorption capacity Inability to swallow oral study treatment or any gastrointestinal disease or condition that would preclude adequate absorption of study treatment Patients with significantly diseased or obstructed gastrointestinal tract, malabsorption, uncontrolled vomiting or diarrhea or inability to swallow oral medications Inability to swallow oral medications Inability to take oral medications Inability to swallow food or any condition of the upper GI tract that precludes administration of oral medications. Inability to swallow oral medication or condition that could interfere with oral absorption or tolerance of treatment Inability to swallow oral medications Inability to swallow or absorb drug Inability to swallow oral medications (unless patients use a feeding tube in which case they are eligible) Patients with significantly diseased or obstructed gastrointestinal tract, malabsorption, uncontrolled vomiting or diarrhea or inability to swallow oral medications Inability to cooperate with NIPPV Inability to swallow study medication Inability to swallow oral medications Inability to take medications by mouth Have a known history of inability to absorb an oral agent Participants with known inability to adequately absorb oral medication Have a known history of inability to absorb an oral agent