Known human immunodeficiency virus (HIV) infection and/or active hepatitis B infection (defined as presence of Hep B DNA), active hepatitis C infection (defined as presence of Hep C RNA).
Patient has known active hepatitis B infection (defined as presence of hepatitis B surface antigen [HepB sAg] and/ or hepatitis B [Hep B] deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of Hep C RNA) and/or known human immunodeficiency virus (HIV); patients with HIV who have a normal CD4 count (>= 200) and an undetectable viral load are not excluded
Patients known to be HIV(+), Hep BsAg(+), or Hep C(+) are excluded as the effect of the agent on immune system has not been assessed
Patients with known active human immunodeficiency virus (HIV), hepatitis (hep) B, or hep C infection
Patients who have active, chronic, or on active treatment for Hep B or Hep C are excluded.
Patient has known active hepatitis B infection (defined as presence of hepatitis B [HepB] surface antigen [sAg] and/or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) carrier (HIV 1/2 antibodies)
Active hepatitis B infection (defined as presence of hepatitis [hep] B surface antigen [sAg] and/ or hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hep C ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) carrier
Known active hepatitis B infection (defined as presence of hepatitis B [HepB] surface antigen [sAg] and/or Hep B deoxyribonucleic acid [DNA]), known active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) carrier
Active infections including hepatitis B carrier status, hepatitis C virus (HCV) infection (patients must have a negative hepatitis [hep] B and hep C viral load at screening)
Patients with known active human immunodeficiency virus (HIV), hepatitis (Hep) B, or Hep C infection will be excluded; if not clinically indicated, the patients do not need to be tested
Has active hepatitis B or hepatitis C infection; patients with a history of hepatitis B/C infection who have received anti-viral therapy and are disease free (hepatitis [Hep] B - negative hepatitis B surface antigen [HBsAg] and HBV deoxyribonucleic acid [DNA]; Hep C – negative HCV ribonucleic acid [RNA]) may be considered for enrollment after discussion with principal investigator
Clinically significant infection, including known human immunodeficiency virus (HIV) or hepatitis C infection, or known hepatitis B (Hep B) surface antigen positivity; patients with Hep B core positivity can be enrolled if the Hep B polymerase chain reaction (PCR) is negative, and they are on antiviral suppression
Active hepatitis B (hepatitis [Hep] B core antibody positive and subsequent Hep B surface antigen positive or Hep B deoxyribonucleic acid [DNA] positive) or hepatitis C infection (Hep C antibody positive and subsequent detectable viral load)
Active infection including hepatitis B-carrier status, hepatitis C virus (HCV) infection (patients must have a negative hepatitis [Hep] B and Hep C viral load at screening)
Patient has known active hepatitis B infection (defined as presence of hepatitis B [HepB] surface antigen (sAg) and/ or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) carrier (HIV 1/2 antibodies)
Active hepatitis B infection (defined as presence of hepatitis B [Hep B] surface antigen [sAg] and/or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) carrier
Virus or active hepatitis B virus infection; patients who are hepatitis B core antibody (Hep B cAb) positive may be eligible as long as there is no evidence of active infection with negative hepatitis B (Hep B) by polymerase chain reaction (PCR); in this case, Hep B PCR must be monitored monthly
Known HIV, or active hep B or hep C infection (detected positive by PCR).
Serologic or clinical evidence of current active hepatitis B or C infection, defined as elevated levels of hepatitis (Hep) B antigen or Hep C antibody (unless active infection is ruled out by nucleic acid tests)
Positive screening tests for human immunodeficiency virus (HIV), hepatitis (Hep) B, Hep C, active tuberculosis or recent (< 2 week ago) clinically significant infection or evidence of active HIV, Hep B, or Hep C. (Note: If positive results are not indicative of true active or chronic infection, the patient can be treated.)
Positive screening tests for HIV, Hep B, and Hep C. If positive results are not indicative of true active or chronic infection, the patient can be treated.
Known hepatitis (hep) B or C, or known cirrhosis (screening for viral hepatitis is not required)
Positive screening tests for human immunodeficiency virus (HIV), hepatitis (Hep) B, and Hep C; if positive results are not indicative of true active or chronic infection, the patient can be treated
Known history of human immunodeficiency virus (HIV), hepatitis B, and/or hepatitis C (no additional laboratory tests for HIV, hepatitis [Hep] B, or Hep C are required for screening)
Patients must not have a known history of active hepatitis B infection (defined as presence of hepatitis B surface antigen [Hep B sAg] and/ or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) seropositive
CLINICAL/LABORATORY CRITERIA: Patients must not have a known history of active hepatitis B or C infection (defined as presence of hepatitis [Hep] B surface antigen [sAg] and/or Hep B deoxyribonucleic acid [DNA] and/or Hep C ribonucleic acid [RNA]); patients must not have a known history of human immunodeficiency virus (HIV) seropositivity
Subject has active hepatitis B or C. Subject with hepatitis in medical history may be eligible if infection considered cleared, ie core Ab+, surface Ab+, surface Ag- for hep B and Ab+/DNA- for hep C.
History of active or chronic hepatitis (e.g. Hep B or C)
No positive Hep C serology or active Hep B infection
Positive screening tests for human immunodeficiency virus (HIV), hepatitis B virus (Hep B), and hepatitis C virus (Hep C). If positive results are not indicative of true active or chronic infection, the patient can be treated.
Positive screening tests for human immunodeficiency virus (HIV), hepatitis B (hep B), and hepatitis C (hep C) (referencing blood draw at leukapheresis screening); if positive results are not indicative of true active or chronic infection, the patient can be treated
Hep B and Hep C
known diagnosis of human immunodeficiency virus or chronic active Hep B or C.
Active, life threatening or clinically significant uncontrolled systemic infection, known human immunodeficiency virus (HIV)-related illness, hepatitis B (Hep B) or hepatitis C (Hep C) infection
Positive serological test for HIV, Hep B or Hep C or history of HIV infection, Hepatitis B or Hepatitis C (women with cured HCV will be allowed; subject must have had an serologic test performed within 12 months of informed consent);
Current or chronic hepatitis B or C infection, or known seropositivity for human immunodeficiency virus (HIV); Note: patients with previous history of hepatitis B (who have cleared the infection and have natural immunity, i.e. hepatitis [Hep] B core antibody positive cases) are excluded if prophylaxis against Hep B reactivation with antiviral agents (such as entecavir) is recommended, after consultation with gastroenterologist/hepatologist or infectious disease team
active (acute or chronic) or uncontrolled severe infection, liver disease such as cirrhosis, decompensated liver disease (except for Hep B and Hep C positive patients)