Symptomatic brain metastasis or leptomeningeal disease Cytologic or unequivocal radiographic confirmation of leptomeningeal metastasis by dural puncture and/or neuroimaging with or without known brain metastasis Or any history of leptomeningeal metastasis. Presence of brain metastasis or leptomeningeal spread of the disease Patients with leptomeningeal metastasis. Patients with a history of brain/leptomeningeal metastasis Leptomeningeal disease or uncontrolled brain metastasis Known brain metastasis or leptomeningeal involvement Patients with leptomeningeal metastasis Leptomeningeal metastasis Active brain or leptomeningeal metastasis. History or presence of brain metastasis or leptomeningeal disease Leptomeningeal metastasis Known brain metastasis or leptomeningeal disease Known brain metastasis or leptomeningeal disease Unstable or untreated brain/leptomeningeal metastasis Current or previously treated brain metastasis or active leptomeningeal disease; History of brain metastasis, active leptomeningeal disease or seizure Patients with a history of brain/leptomeningeal metastasis Active brain metastasis or leptomeningeal metastasis Widespread definitive leptomeningeal metastasis Any history of leptomeningeal metastasis. Known brain metastasis or leptomeningeal disease Any presence of leptomeningeal disease or any parenchymal brain metastasis Leptomeningeal metastasis. Brain metastasis, leptomeningeal disease. The participant has symptomatic brain or leptomeningeal metastasis. The participant has symptomatic brain or leptomeningeal metastasis.