No inflammatory breast cancer Participant with inflammatory breast cancer. Inflammatory breast cancer Diagnosis of inflammatory breast cancer FOR ALL PHASES (Ib AND II): Inflammatory breast cancer Inflammatory breast cancer Diagnosis of inflammatory breast carcinoma Inflammatory (T4d) breast cancer Documentation of inflammatory breast cancer Inflammatory breast cancer or patients with rapidly progressing metastatic breast cancer Diagnosis of inflammatory breast cancer Have no inflammatory breast cancers Patients with bilateral or inflammatory breast cancer Inflammatory breast cancer Inflammatory breast cancer Patients with inflammatory breast carcinoma Patients with inflammatory breast cancer Bilateral or inflammatory breast cancer Inflammatory breast cancer Inflammatory breast cancer or tumor with deep adherence or cutaneous invasion Diagnosis of inflammatory breast cancer Patients must have the clinical diagnosis of inflammatory breast cancer Patients with inflammatory breast cancer Subject has inflammatory breast cancer Inflammatory breast cancer Patients must not have inflammatory breast cancer and must not have metastatic disease Active inflammatory breast cancer Patient with inflammatory breast cancer at screening Subject has inflammatory breast cancer Inflammatory breast cancer or tumor with deep adherence or cutaneous invasion; Subjects with Inflammatory breast cancer. Inflammatory breast cancer Patient with inflammatory breast cancer at screening . Patients who currently have inflammatory breast cancer at screening. Have inflammatory breast cancer Inflammatory/inoperable breast cancer. Patients must not have inflammatory breast cancer (T4d) and must not have metastatic breast cancer (stage IV disease) Male and female participants with locally advanced, inflammatory, or early-stage, unilateral, and histologically confirmed invasive breast cancer. Participants with inflammatory breast cancer must be able to have a core needle biopsy Evidence of inflammatory breast cancer Inflammatory breast cancer. Inflammatory breast cancer Patient with inflammatory breast cancer Inflammatory or metaplastic breast cancer Subjects with inflammatory breast cancer Subjects with a diagnosis of non-inflammatory breast cancer or carcinoma in situ Subjects with Inflammatory breast cancer. Patients with inflammatory breast cancer are eligible for the escalation phase of the mastectomy cohort Inflammatory breast cancer patients are ineligible, except in the escalation phase of the mastectomy cohort Inflammatory breast malignancy Participants with inflammatory breast cancer or multi-centric disease Participants with locally advanced breast cancer such as inflammatory breast cancer or cancer grossly involving skin Inflammatory breast cancer Patients with stage T1 or greater (T1-T4), nodal involvement (N0-N3), without metastasis (M0) invasive breast cancer, including patients with inflammatory breast cancer Any patient with confirmed metastatic disease. Patients with inflammatory breast cancer.