Presence of an active uncontrolled infection. Presence of a serious acute infection or chronic infection Presence of another major cancer. Presence of N2-3 or M1 disease Presence of serious infection Presence of an active, uncontrolled infection Presence of active or chronic infection Presence of T3 or T4 disease Presence of uncontrolled infection Presence of active infection Presence of serious infection Presence of active infection Patients with the presence of an active infection, abscess or fistula Presence of any serious or uncontrolled infection Presence of active infection within 72 hours Presence of active serious infection; Presence of an active uncontrolled infection. Presence of active clinically serious infection Presence of uncontrolled infection Presence of uncontrolled infection Presence of uncontrolled infection Presence of uncontrolled infection Presence of infection other than the infection of the bile duct (cholangitis) Presence of uncontrolled infection Presence of uncontrolled infection requiring systemic therapy Presence of uncontrolled infection Presence of uncontrolled infection. Presence of another active cancer Presence of uncontrolled infection Presence of active, uncontrolled infection. Presence of uncontrolled infection. Presence of active infection Presence of uncontrolled infection Presence of an uncontrolled infection or infection that required intravenous treatment within 7 days of entry Presence of an active uncontrolled infection. Presence of active infection within 72 hours Presence of angiolymphatic invasion Patients must not have presence of uncontrolled infection