Must be obtained within 14 days prior to registration for protocol therapy: Absolute neutrophil count (ANC) >= 1,500/mcL Absolute neutrophil count (ANC) >= 1,500/mL within 28 days prior to registration Absolute neutrophil count (ANC) > 1500 mm^3, must be obtained within 8 weeks prior to screening for protocol therapy Absolute neutrophil count (ANC) of >= 1,500/mL within 21 days prior to registration; patients must not have had a blood transfusion within 28 days prior to registration Absolute neutrophil count (ANC) >= 1,500/mcl obtained within 28 days prior to sub-study registration Absolute neutrophil count >= 1,500/mm^3 must be obtained =< 7 days prior to protocol registration Absolute neutrophil count (ANC) >= 1,000/mcL; must be obtained within 28 days prior to registration Absolute neutrophil count (ANC) >= 1,500 microliter (mcL), obtained within 28 days prior to step 2 registration Within 60 days prior to registration on study: Absolute neutrophil count (ANC) >= 1,500/mm^3 Within less than or equal to 14 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Within 14 days of registration: Absolute neutrophil count (ANC) >= 1,500/mm^3 Obtained within 28 days prior randomization: absolute neutrophil count (ANC) must be >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1,500/mm^3 obtained =< 21 days prior to registration Absolute neutrophil count (ANC) >= 1.5 x 10^9/L within 14 days prior to registration. Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1,500/mcl Obtained within 14 days prior to treatment start: Absolute neutrophil count >= 1.5 × 10^9/L Obtained =< 21 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1,500/mm^3 (=< 28 days prior to registration) Absolute neutrophil count (ANC) >= 1.5 K/mm^3 obtained within 14 days prior to registration Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1500 obtained =< 14 days prior to registration Obtained within 21 days prior to study registration: absolute neutrophil count >= 1,500/mcL Obtained =< 21 days prior to registration: absolute neutrophil count (ANC) >= 1000/uL Obtained =< 2 weeks prior to registration: Absolute neutrophil count >= 1500/mm^3 Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Obtained within 14 days prior to registration: Absolute neutrophil count (ANC) >= 1,500/uL Absolute neutrophil count (ANC) >= 1,500 cells/mm^3 obtained within 30 days prior to registration Obtained =< 21 days prior to registration and confirmed prior to the first dose of study drug: Absolute neutrophil count (ANC) >= 1000/uL Obtained =< 35 days prior to registration: absolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1000/mm^3, obtained =< 14 days prior to registration OBTAINED =< 7 DAYS PRIOR TO REGISTRATION: Absolute neutrophil count (ANC) >= 1500/uL Absolute neutrophil count >= 0.5 x 10^9/L (obtained =< 14 days prior to registration) Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =< 28 days prior to registration Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1000/mm^3 Absolute neutrophil count (ANC) >= 1000 per mm^3 obtained within 14 days prior to initiating study treatment. Obtained ? 14 days prior to registration: Absolute neutrophil count (ANC) ? 1000/mm^3 Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1500 uL Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Absolute neutrophil count (ANC) >= 1,500 / ml obtained =< 14 days prior to study initiation Absolute neutrophil count (ANC) >= 1500/mm^3 (measured within 28 days of registration) Obtained within 28 days prior to registration: absolute neutrophil count (ANC) >= 1,500 cells/mm^3 Absolute neutrophil count (ANC) ? 1.5 × 10^9/L obtained ? 14 days prior to randomization Absolute neutrophil count (ANC) >= 1000/mm^3 obtained =< 14 days prior to registration Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Obtained within 21 days of registration: absolute neutrophil count (ANC) > 1,500/mcL Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1000/mm^3 Obtained =< 28 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Within 14 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Absolute neutrophil count (ANC) >= 1500/uL obtained =< 14 days prior to registration Peripheral absolute neutrophil count (ANC) >= 1000/mm^3 within 14 days of registration Within 28 days prior to registration for protocol therapy: Absolute neutrophil count (ANC) >= 1,500 K/mm^3 Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =< 7 days prior to registration Absolute neutrophil count (ANC) >= 1000/mm^3 obtained =< 14 days prior to registration Performed within 14 days (+ 3 working days) prior to registration: Absolute neutrophil count (ANC) > 1,500/mm^3. Absolute neutrophil count (ANC) >= 1000/mm^3 (obtained =< 14 days prior to registration) Absolute neutrophil count (ANC) >= 1.5 x 10^9/L (>= 1500 per mm^3) within 28 days prior to study registration FOR MULTIPLE MYELOMA ONLY: Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1000/uL Absolute neutrophil count (ANC) >= 1500/mm^3, obtained =< 14 days prior to registration Obtained =< 7 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =< 14 days prior to registration Absolute neutrophil count (ANC) >= 1000/uL obtained =< 14 days prior to registration Obtained within 14 days prior to registration; absolute neutrophil count (ANC) ?1,500 cells/mm^3 Within 60 days prior to registration, hematologic minimal values: absolute neutrophil count > 1,500/mm^3 Obtained =< 14 days prior to randomization: Absolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1000 (within 14 days prior to registration) Obtained =< 14 days prior to registration: Absolute neutrophil count (ANC) >= 1500 Obtained =< 14 days prior to registration: Absolute neutrophil count >= 1000/mm^3 Absolute neutrophil count (ANC) >= 1500/mm^3, obtained =< 7 days prior to registration Absolute neutrophil count (ANC) >= 1000/ucl obtained within 28 days prior to registration Absolute neutrophil count >= 1.5 x 10^9/L, obtained within 30 days of study registration Absolute neutrophil count (ANC) >= 1000/uL, obtained =< 14 days prior to registration Absolute neutrophil count (ANC) >= 1500/uL (obtained =< 7 days prior to registration) Within 14 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Absolute neutrophil count (ANC) >= 1500/mcL (1.5 x 10^9/L) obtained within 2 weeks prior to registration Absolute neutrophil count (ANC) >= 1.5 X 10^9/L (performed within 14 days prior to registration) Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =< 14 days prior to registration Obtained =< 28 days prior to randomization:\r\nAbsolute neutrophil count (ANC) >= 1500/mm^3 Absolute neutrophil count (ANC) >= 1000/mm^3 obtained =< 14 days prior to registration Absolute neutrophil count (ANC) >= 1500/mm^3, obtained =< 14 days prior to registration Obtained ? 14 days prior to registration: absolute neutrophil count (ANC) ? 1000/mm^3 Absolute neutrophil count >= 1.5 × 10^9/L =< 14 days prior to registration Obtained =< 21 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1,500 cells/mm^3 Obtained =< 7 days prior to registration: Absolute neutrophil count >= 1500/uL Within 14 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 x 10^9/L Within 7 days prior to study registration: Peripheral absolute neutrophil count (ANC) >= 1000/mm^3 Absolute neutrophil count (ANC) >= 1500/mm^3 (1.50 x 10^9 /L) obtained =< 28 days prior to registration Absolute neutrophil count (ANC) >= 1500/mm^3, unless secondary to bone marrow involvement; obtained =< 7 days prior to registration Absolute neutrophil count >= 1500 cells/mm^3, obtained within 14 days prior to registration for protocol therapy ARM A: obtained =< 14 days prior to registration: \r\n* Absolute neutrophil count (ANC) >= 1000/mm^3 ARM B: obtained =< 14 days prior to registration: \r\n* Absolute neutrophil count (ANC) >= 1000/mm^3 Absolute neutrophil count (ANC) >= 1500/mm^3 or >= 1.5 x 10^9/L, obtained =< 14 days prior to registration Obtained within 30 days prior to registration: Absolute neutrophil count (ANC) >= 1.5 K/mm^3 Obtained =< 7 days prior to registration: Absolute neutrophil count (ANC) >= 1700/mm^3 Absolute neutrophil count (ANC) >= 1,500/mcl obtained within 28 days prior to Step 2 re-registration Absolute neutrophil count (ANC) >= 1500/mm^3 (obtained =< 14 days prior to registration) Absolute neutrophil count (ANC) >= 1,500/mcl obtained within 28 days prior to Step 2 re-registration Absolute neutrophil count (ANC) >= 1,500/mcl obtained within 28 days prior to step 2 re-registration Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1,500/mcL Absolute neutrophil count (ANC) >= 1,500/mcL; these results must be obtained within 28 days prior to registration Absolute neutrophil count (ANC) >= 1,500 microliter (mcL) be obtained within 42 days prior to registration CLINICAL/LABORATORY CRITERIA: Absolute neutrophil count (ANC) >= 1500/mcL; these results must be obtained within 28 days prior to registration Absolute neutrophil count (ANC) >= 1,500/mcL obtained within 28 days prior to registration Absolute neutrophil count (ANC) >= 1,500/mcl obtained within 28 days prior to RE-TREATMENT registration Absolute neutrophil count (ANC) >= 1000/mm^3, obtained =< 21 days prior to registration Obtained within 30 days of registration: Absolute neutrophil count >= 1,500/mcL Absolute neutrophil count (ANC) >= 1,500/mm^3 (1.5 x 10^9/L) (unless due to marrow involvement) obtained within 4 weeks prior to registration Absolute neutrophil count (ANC) >= 1000/mm^3 obtained =< 7 days prior to registration Absolute neutrophil count (ANC) >= 1000/uL, obtained =< 21 days prior to registration and confirmed prior to the first dose of study drug Absolute neutrophil count (ANC) >= 1.5 X 10^9/L (> 1500 per mm^3), obtained within 14 days prior to first treatment Absolute neutrophil count (ANC) > 1.5 x 10^9/L (within 7 days prior to registration) Obtained within 14 weeks prior to registration on study: absolute neutrophil count (ANC) >= 1,800 cells/mm^3 Absolute neutrophil count (ANC) >= 1.5 x 10^9/L obtained within 14 days prior to registration Absolute neutrophil count (ANC) >= 750 /uL obtained =< 7 days prior to registration Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =< 14 days prior to registration Absolute neutrophil count (ANC) > 1500/mm^3 (obtained =< 7 days prior to randomization) Absolute neutrophil count (ANC) >= 1500/mm^3 obtained =<14 days prior to randomization Obtained =< 21 days prior to registration: Absolute neutrophil count (ANC) >= 1000/uL Absolute neutrophil count (ANC) >= 1.5 x 10^9/L (tested within 14 days prior to registration) Obtained =< 7 days prior to registration: Absolute neutrophil count (ANC) >= 1500/mm^3 Obtained within 14 days prior to registration: Absolute neutrophil count (ANC) >= 1,500/ul Absolute neutrophil count (ANC) >= 1,500/mm^3 obtained =< 14 days prior to randomization Absolute neutrophil count >= 1000/mL (obtained =< 14 days prior to registration) Absolute neutrophil count (ANC) >= 1.5 x 10^9/L (> 1500 per mm^3), obtained within 14 days prior to first treatment Absolute neutrophil count (ANC) >= 1000/uL obtained =< 14 days prior to registration Absolute neutrophil count (ANC) >= 1500/?L obtained =< 7 days prior to registration Absolute neutrophil count (ANC) > 1500 mm^3 for 14 days prior to registration Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >= 1500 cells/uL Absolute neutrophil count (ANC) >= 1,500/mm^3, obtained within 14 days prior to C11-AMT PET scan Absolute neutrophil count (ANC) >= 1,500 /mcL, obtained =< 30 days prior to registration Absolute neutrophil count (ANC) >= 1,500/mm^3, performed within 28 days prior to registration