Patients with a corrected QT interval (QTc) > 480 msecs are NOT eligible for participation Corrected QT interval (QTc) > 480 msecs using Bazett’s formula Corrected QT interval (QTc) > 480 msecs using Bazett’s formula Corrected QT (QTc) interval =< 450 msecs Corrected QT (QTc) interval =/< 470 msecs, no familial history of QTc prolongation or ventricular arrhythmias Corrected QT interval (QTc) > 480 msecs Baseline cardiac QTc interval > 450 msecs Corrected QT interval (QTc) > 480 msecs using Bazett‘s formula Corrected QT interval (QTc) > 480 msecs using Bazett's formula Corrected QT (QTC) by 12 lead electrocardiography (EKG) < 450 msecs Corrected QT (using Bazett's formula [QTcB]) interval < 500 msecs Corrected QT interval (QTc) > 480 miliseconds (msecs) Cardiac function: baseline corrected QT (QTc) interval =< 450 msecs Baseline cardiac QTc interval > 450 msecs Corrected QT interval (QTc) > 480 msecs using Bazett's formula; electrocardiography (EKG) for screening must be =< 28 days before registration Patients must not have a corrected QT (QTc) interval >= 480 msecs within 28 days prior to registration QTc\t=< 480 msecs Corrected QT interval (QTc) > 480 msecs\r\n* Note: correction method should be reported Corrected QT (QTc) interval greater than or equal to 480 msecs (>= 500 msec for subjects with bundle branch block) Corrected QT interval (QTc) < 480 msecs Corrected QT interval (QTc) > 480 msecs using Bazett’s formula Corrected QT interval (QTc) > 480 msecs using Bazett’s formula QTcF interval greater than 500 msecs at the time of transition to this study. Prolongation of corrected QT interval (QTc) > 480 msecs Subjects with a baseline corrected QT (QTc) of equal to or greater than 480 msecs or other significant electrocardiogram (ECG) abnormalities Corrected QT interval (QTc) > 480 msecs using Bazett’s formula Prolongation of corrected QT interval (QTc) > 480 msecs Prolongation of corrected QT interval (QTc) > 480 msecs EXPANSION COHORT ONLY: Prolongation of corrected QT interval (QTc) > 480 msecs Corrected QT interval (QTc) > 480 msecs using Bazett’s formula Corrected QT interval (QTc) > 480 msecs using Bazett's formula. Corrected QT (QTc) interval using Bazett's Formula; (QTcB) >= 480 msecs Corrected QT interval > 480 msecs using Bazett's formula. QTc interval greater than or equal to 480msecs. Corrected QT interval (QTc) > 480 msecs Corrected QT interval (QTc) > 480 msecs (record QTc correction method) Patient must not have corrected QT interval (QTc) > 480 msecs using Bazett’s formula