Unwillingness to give written informed consent
Unwillingness to undergo RPFNA
Inability or unwillingness to give informed consent
Inability or unwillingness to swallow
Noncompliance - inability or unwillingness to comply with medical recommendations regarding therapy or follow-up, including smoking tobacco
Unwillingness to be transfused with blood components
Unwillingness or inability to given written informed consent.
Inability or unwillingness to sign the informed consent form.
Inability or unwillingness to tolerate endocrine therapy
Inability or unwillingness to have pleural catheter placed
Inability or unwillingness to receive antithrombotic therapy
Unwillingness or inability to receive conventional chemotherapy
Regular use of thiazide diuretics (i.e., hydrochlorothiazide), which can lead to hypercalcemia, and unwillingness or inability to discontinue or switch to alternative anti-hypertensive agent
Unwillingness to maintain adequate contraception measures for the entire course of the study
Inability or unwillingness to take folic acid, vitamin B12 supplementation or corticosteroids
Inability or unwillingness to take folic acid or vitamin B12 or dexamethasone
Unwillingness to stop calcium supplementation (during the first cycle of treatment) or vitamin D supplementation throughout the study
Unwillingness to stop calcium supplementation
Unwillingness to be transfused with blood components.
Failure/inability/unwillingness to provide names and contact information for two family members or friends to serve as emergency contacts during the course of the study
Inability or unwillingness of individual to give written informed consent
Unwillingness or inability to cooperate, or, for the parents or guardians of minors, to give consent, or for the child to give assent, or any condition of sufficient severity to impair cooperation with the study
Inability or unwillingness to give informed consent
Inability or unwillingness of individual to give written informed consent
Inability or unwillingness to abstain from non-protocol use of aspirin or NSAIDs or to provide blood, urine, or stool samples or colon biopsies during the study
Unwillingness to prevent pregnancy during the medication phase and 1 month afterwards (women only)
Unwillingness or inability to participate or give informed consent
Inability or unwillingness of patient, parent, or guardian to consent
Inability or unwillingness to provide informed consent to the study
Inability or unwillingness to undergo PET scanning
Inability or unwillingness to cooperate with requirements of this trial
Inability or unwillingness to undergo the complete series of imaging sessions; inability or unwillingness to complete the one month follow-up
Unwillingness or inability to give informed consent
Regular use of thiazide diuretics (i.e., hydrochlorothiazide), which can lead to hypercalcemia, and unwillingness or inability to discontinue or switch to an alternative anti-hypertensive agent
Unwillingness to engage in adequate contraception