Participant must be aware of the nature of her malignancy, understand the study requirements and risks and be able and willing to sign a written informed consent document Subject must be able to understand and be willing to sign a written informed consent document Participant is able to understand and comply with study requirements and is willing to sign a written informed consent document Able to understand and willing to sign written informed consent. Patient must be able to understand and willing to sign a written informed consent document Subject must sign a written informed consent document Able to understand, and willing to sign, a written informed consent document. Patient must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Ability to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Patients must be willing and able to understand the informed consent document Able to understand, and willing to sign a written informed consent document Patient must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and sign a written informed consent document and complete study-related procedures and questionnaires Able to understand and sign a written informed consent document. Patients must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Subjects must be able to understand and be willing to sign a written informed consent document Be able to understand and be willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Participants must be able to understand and willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document Patient needs to be able to understand and demonstrate willingness to sign a written informed consent document AMKL PATIENTS: Patients must be able to understand and willing to sign a written informed consent MF PATIENTS: Patients must be able to understand and willing to sign a written informed consent Patient needs to be able to understand and demonstrate willingness to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document. Ability to understand and willing to sign a written informed consent document The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Patients able to understand and willing to sign a written informed consent documents Participants must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document. Patient must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Able to understand and to sign a written consent document Patients must be able to understand and be willing to sign a written informed consent document Patients must be able to understand and willing to sign a written informed consent document RECURRENT/ PROGRESSIVE DIPG (STRATUM 1): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines NON-PROGRESSED DIPG (STRATUM 2): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelines Patient must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Ability to understand and willing to sign a written informed consent document Ability to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document The ability to understand and be willing to sign an informed consent document Able to understand and willing to sign a written informed consent document Participants must be able to understand and willing to sign a written informed consent document Participants must be able to understand and be willing to sign a written informed consent document Patients must have the ability to understand English, sign a written informed consent document, and be willing to follow protocol requirements The patient understands the study requirements and is willing and able to sign an informed consent document Sign a written informed consent document Participants must be able to understand and willing to sign a written informed consent document Patient must be able to understand and willing to sign a written informed consent document Ability of subject to understand and willing to sign a written informed consent document AIMS 1 AND 2: Participants must be able to understand and willing to sign a written informed consent document AIM 3: Participants must be able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Able to understand and willing to sign a written informed consent document Must be able to understand and sign a written informed consent document Patients must be able to understand and be willing to sign a written informed consent document to participate Patients who are able to understand the investigational nature of this study and agree to sign a written informed consent document