Appropriate stage for protocol entry, based upon the following minimum diagnostic workup within 60 days prior to registration:* History/physical examination including weight, performance data, body surface area Complete history and physical examination including weight and Zubrod status within 31 days of study entry (or within 31 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration) Prestudy history and physical must be obtained within 28 days prior to registration Patients must have a complete history and physical examination within 28 days prior to registration Patients must have a complete history and physical examination within 28 days prior to registration History/physical examination (to include at a minimum digital rectal examination of the prostate and examination of the skeletal system and abdomen) within 90 days prior to registration History/physical examination within 21 days prior to study entry Patients must have a complete history and physical examination within 28 days prior to registration Patients must have history and physical examination within 28 days prior to registration Patients must have a complete physical examination and medical history within 28 days prior to registration Patients must have complete history and physical examination within 28 days prior to registration Prestudy history and physical exam must be obtained within 28 days prior to sub-study registration History/physical examination within 45 days prior to study registration Prestudy history and physical must be obtained within 28 days prior to registration Patients must have complete history and physical examination within 28 days prior to registration History/physical examination within 28 days prior to step 2 registration Prestudy history and physical must be obtained with 28 days prior to registration Prestudy history and physical must be obtained within 3 days prior to registration Prestudy history and physical must be obtained with 28 days prior to registration History and physical examination within 28 days prior to Step 2 registration Prestudy history and physical must be obtained within 28 days prior to registration Patients must have a complete physical examination and medical history within 28 days prior to registration Patients must have a complete history and physical examination within 28 days prior to registration Patients must have a complete physical examination and medical history within 28 days prior to registration Appropriate stage for study entry based on the following diagnostic workup:* History/physical examination within 28 days prior to registration* Imaging of target lesion(s) within 28 days prior to registration* Completion of pre-study protocol specific assessments as required Patients must have complete history and physical examination within 28 days prior to registration History/physical examination, including neurologic examination within 60 days prior to step 2 registration Patients must have complete physical examination and medical history obtained within 28 days prior to registration Patients must have a complete history and physical examination within 28 days prior to registration Appropriate stage for study entry based on the following diagnostic workup:* History/physical examination within 42 +/- 5 days of planned surgical procedure (18-21 days from day 1);* Further protocol-specific assessments Patients must have complete history and physical examination within 28 days prior to registration Appropriate stage for study entry based on the following diagnostic workup:* History/physical examination within 60 days prior to registration* Magnetic resonance imaging (MRI) of the brain with contrast within 30 days prior to registration