All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent (patient assent is also recommended when applicable according to each institution�s policy) All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent; assent, when appropriate, will be obtained according to institutional guidelines All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent Each patient�s parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent. All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent; assent, when appropriate, will be obtained according to institutional guidelines All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent All patients and/or their parents or legal guardians must sign a written informed consent