Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1 Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1 Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1 Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1 Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1 Patients must not have clinical signs or symptoms of active tuberculosis infection Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1