[c09aa8]: / clusters / final340numclusters / clust_47.txt

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Major surgical procedures, or significant traumatic injury =< 14 days prior to registration or anticipation of need for elective or planned major surgical procedure during the course of the study
Invasive procedures defined as follows:* Major surgical procedure, open biopsy or significant traumatic injury within 28 days prior to day 1 therapy* Anticipation of need for major surgical procedures during the course of the study* Core biopsy within 7 days prior to day 1 therapy
Major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to starting cediranib
Major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to starting cediranib
Patients who have had or are planning to have the following invasive procedures are not eligible:* Major surgical procedure, laparoscopic procedure, open biopsy or significant traumatic injury within 28 days prior to enrollment* Central line placement or subcutaneous port placement is not considered major surgery; external central lines must be placed at least 3 days prior to enrollment and subcutaneous ports must be placed at least 7 days prior to enrollment* Core biopsy within 7 days prior to enrollment* Fine needle aspirate within 7 days prior to enrollment* Surgical or other wounds must be adequately healed prior to enrollment; Note: for purposes of this study, bone marrow aspirate and biopsy are not considered surgical procedures and therefore are permitted within 14 days prior to start of protocol therapy
A major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to starting cediranib (percutaneous/endobronchial biopsies are allowed)
No excess risk of bleeding (any of the following):* Bleeding diathesis or coagulopathy* Thrombocytopenia* Major surgical procedure, open biopsy, or significant traumatic injury within the past 28 days or anticipation of need for major surgical procedure during the course of the study* Minor surgical procedures, stereotactic biopsy, fine needle aspiration, or core biopsy within the past 7 days
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study
Major surgical procedure within 28 days prior to cycle 1, day 1 and patients must have recovered from any effects of any major surgery; anticipation of need for a major surgical procedure during the course of the study
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study
Patients who have had or are planning to have the following invasive procedures are not eligible:* Major surgical procedure, laparoscopic procedure, or open biopsy within 28 days prior to enrollment* Central line placement or subcutaneous port placement is not considered major surgery but must be placed at least 3 days prior to enrollment for external lines (e.g., Hickman or Broviac catheter, peripherally inserted central catheter [PICC]) and at least 7 days prior to enrollment for a subcutaneous port* Core biopsy within 7 days prior to enrollment* Fine needle aspirate within 7 days prior to enrollment* Surgical or other wounds must be adequately healed prior to enrollment* NOTE: For purposes of this study, bone marrow aspirate and biopsy are not considered surgical procedures and therefore are permitted within 14 days prior to start of protocol therapy
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study with the exception of the planned breast cancer surgery that is part of the trial design
A major surgical procedure, open biopsy, or significant traumatic injury within 3 months prior to cycle 1 day 1 (percutaneous/endobronchial/endoscopic biopsies are allowed)
Patients who have had or are planning to have the following invasive procedures are not eligible:* Major surgical procedure, laparoscopic procedure, open biopsy or significant traumatic injury within 28 days prior to enrollment* Subcutaneous port placement or central line placement is not considered major surgery; external central lines must be placed at least 3 days prior to enrollment and subcutaneous ports must be placed at least 7 days prior to enrollment* Core biopsy within 7 days prior to enrollment* Fine needle aspirate within 7 days prior to enrollment* NOTE: For purposes of this study, bone marrow aspirate and biopsy are not considered surgical procedures and therefore are permitted within 14 days prior to start of protocol therapy
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study
Invasive procedures defined as follows:* Major surgical procedure, open biopsy or significant traumatic injury within 28 days prior to day 1 therapy* Anticipation of need for major surgical procedures during the course of the study* Core biopsy within 7 days prior to day 1 (D1) therapy
Participants may not have a major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to starting cediranib; anticipation of need for major surgical procedures during the course of the study also excludes patients from the trial
Patients with a major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to initiation of therapy, or anticipation of need for major surgical procedure during the course of the study other than that defined by protocol are ineligible
Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study