In adults: serum creatinine =< 1.5 mg/dl or creatinine clearance > 60 ml/min; and in children serum creatinine (Cr) =< age-adjusted normal* Age 12-15 years: 1.2 mg/dl* Age > 15 years: 1.5 mg/dl Creatinine below age-adjusted maximum limits in the table below OR creatinine clearance >= 60 mL/min/1.73 m^2 assessed within seven (7) days prior to the start of therapy* 0.8 mg/dl (patients =< 5 years of age)* 1.0 mg/dl (patients 5 < age =< 10 years of age)* 1.2 mg/dl (patients 10 < age =< 15 years of age)* 1.5 mg/dl (patients > 15 years of age) Age-adjusted serum creatinine =< 1.5 x normal for age or creatinine clearance or glomerular filtration rate (GFR) >= 60 cc/min/1.73 m^2* Age 1 month to < 6 months: 0.4 mg/dL for males and 0.4 mg/dL for females* Age 6 months to < 1 year: 0.5 mg/dL for males and 0.5 mg/dL for females* Age 1 to < 2 years: 0.6 mg/dL for males and 0.6 mg/dL for females* Age 2 to < 6 years: 0.8 mg/dL for males and 0.8 mg/dL for females* Age 6 to < 10 years: 1.0 mg/dL for males and 1.0 mg/dL for females* Age 10 to < 13 years: 1.2 mg/dL for males and 1.2 mg/dL for females* Age 13 to < 16 years: 1.5 mg/dL for males and 1.4 mg/dL for females* Age >= 16 years: 1.7 mg/dL for males and 1.4 mg/dL for females A serum creatinine =< upper limit of normal (ULN) based on age/gender as follows:* Age 1 month to < 6 months: 0.4 for males, 0.4 for females* Age 6 months to < 1 year: 0.5 for males, 0.5 for females* Age 1 to < 2 years: 0.6 for males, 0.6 for females* Age 2 to < 6 years: 0.8 for males, 0.8 for females* Age 6 to < 10 years: 1 for males, 1 for females* Age 10 to < 13 years: 1.2 for males, 1.2 for females* Age 13 to < 16 years: 1.5 for males, 1.4 for females* Age >= 16 years: 1.7 for males, 1.4 for females Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73m^2 or a serum creatinine based on age as follows, within 14 days of registration and within 7 days of the start of treatment:* =< 5 years: 0.8 mg/dL* > 5 years but =< 10 years: 1 mg/dL* > 10 years but =< 15 years: 1.2 mg/dL* > 15 years: 1.5 mg/dL Creatinine within normal limits based on age as follows:* Age (years): maximum serum creatinine (mg/dL)** =< 5: 0.8 mg/dL** 5 < age =< 10: 1.0 mg/dL** 10 < age =< 15: 1.2 mg/dL** > 15: 1.5 mg/dLOR creatinine clearance >= 60 mL/min for adults or >= 60 mL/min/1.73m^2 for children with creatinine levels above institutional upper limit of normal Serum creatinine =< 1.5 x the upper limit of normal for age, or calculated creatinine clearance or nuclear glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2* =< 0.6 mg/dL (1 to < 2 years of age)* =< 0.8 mg/dL (2 to < 6 years of age)* =< 1.0 mg/dL (6 to < 10 years of age)* =< 1.2 mg/dL (10 to < 13 years of age)* =< 1.4 mg/dL (females >= 13 years of age)* =< 1.5 mg/dL (males 13 to < 16 years of age)* =< 1.7 mg/dL (males >= 16 years of age) Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age 1 to < 2 years: 0.6 mg/dL* Age 2 to < 6 years: 0.8 mg/dL* Age 6 to < 10 years: 1 mg/dL* Age 10 to < 13 years: 1.2 mg/dL* Age 13 to < 16 years: 1.5 mg/dL (males), 1.4 mg/dL (females)* Age >= 16 years: 1.7 mg/dL (males), 1.4 mg/dL (females) Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* 1 to < 2 years: =< 0.6 mg/dL* 2 to < 6 years: =< 0.8 mg/dL* 6 to < 10 years: =< 1 mg/dL* 10 to < 13 years: =< 1.2 mg/dL* 13 to < 16 years: =< 1.5 mg/dL (males) and =< 1.4 mg/dL (females)* >= 16 years: =< 1.7 mg/dL (males) and =< 1.4 mg/dL (females) Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a maximum serum creatinine (mg/dL) based on age/gender as follows:* 1 to < 2 years: 0.6 * 2 to < 6 years: 0.8 * 6 to < 10 years: 1 * 10 to < 13 years: 1.2 * 13 to < 16 years: 1.5 for males, 1.4 for females* >= 16 years: 1.7 for males, 1.4 for females Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age 1 to < 2 years: maximum serum creatinine (mg/dL) 0.6 for males and females* Age 2 to < 6 years: 0.8 for males and females* Age 6 to < 10 years: 1 for males and females* Age 10 to < 13 years: 1.2 for males and females* Age 13 to < 16 years: 1.5 for males and 1.4 for females* Age >= 16 years: 1.7 for males and 1.4 for females Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age < 6 months: Maximum serum creatinine (mg/dL): 0.4 for males and females* Age 6 months to < 1 year: Maximum serum creatinine (mg/dL): 0.5 for males and females* Age 1 to < 2 years: Maximum serum creatinine (mg/dL): 0.6 for males and females* Age 2 to < 6 years: Maximum serum creatinine (mg/dL): 0.8 for males and females* Age 6 to < 10 years: Maximum serum creatinine (mg/dL): 1 for males and females* Age 10 to < 13 years: Maximum serum creatinine (mg/dL): 1.2 for males and females* Age 13 to < 16 years: Maximum serum creatinine (mg/dL): 1.5 for males and 1.4 for females* Age >= 16 years: Maximum serum creatinine (mg/dL): 1.7 for males and 1.4 for females Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age 1 to < 2 years: maximum serum creatinine 0.6 mg/dL (males and females)* Age 2 to < 6 years: maximum serum creatinine 0.8 mg/dL (males and females)* Age 6 to < 10 years: maximum serum creatinine 1.0 mg/dL (males and females)* Age 10 to < 13 years: maximum serum creatinine 1.2 mg/dL (males and females)* Age 13 to < 16 years: maximum serum creatinine 1.5 mg/dL (males) and 1.4 mg/dL (females)* Age >= 16 years: maximum serum creatinine 1.7 mg/dL (males) and 1.4 mg/dL (females) Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* 3 to < 6 years of age: maximum (max) serum creatinine 0.8 mg/dL (males and females)* 6 to < 10 years of age: max serum creatinine 1 mg/dL (males and females)* 10 to < 13 years of age: max serum creatinine 1.2 mg/dL (males and females)* 13 to < 16 years of age: max serum creatinine 1.5 md/dL (males) and 1.4 md/dL (females)* >= 16 years of age: max serum creatinine 1.7 mg/dL (males) and 1.4 mg/dL (females)** The threshold creatinine values were derived from the Schwartz formula for estimating GFR utilizing child length and stature data published by the Centers for Disease Control and Prevention (CDC) Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* 1 to < 2 years: 0.6 mg/dL for males and females* 2 to < 6 years: 0.8 mg/dL for males and females* 6 to < 10 years: 1.0 mg/dL for males and females* 10 to < 13 years: 1.2 mg/dL for males and females* 13 to < 16 years: 1.5 mg/dL for males and 1.4 mg/dL for females* > = 16 years: 1.7 mg/dL for males and 1.4 mg/dL for females Creatinine clearance or radioisotope glomerular filtration rate (GFR) > 60 mL/min/1.73 m^2 by either Cockcroft-Gault formula or analysis normal serum creatinine based on age described below:* =< 5 years, 0.8 mg/dL* 5 < age =< 10 years, 1.0 mg/dL* 10 < age =< 15 years, 1.2 mg/dL* > 15 years, 1.5 mg/dL