Patient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXPatient must be able to provide study specific informed consent prior to study entryXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to step 1 registrationXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entry.Xx_NEWLINE_xXPatients must provide study-specific informed consent prior to step 1 registrationXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entry, including the mandatory pre-treatment plasma EBV DNA assayXx_NEWLINE_xXPatients must provide study specific informed consent prior to study entry, including consent for mandatory tissue submission for central reviewXx_NEWLINE_xXPatient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXSigned informed consent prior to study specific procedures.Xx_NEWLINE_xXVoluntarily consents to participate and provides written informed consent prior to any protocol-specific proceduresXx_NEWLINE_xXProvision of signed and dated, written informed consent prior to any study specific proceduresXx_NEWLINE_xXSigned informed consent prior to the performance of any study-specific procedures, including fresh tumor biopsies.Xx_NEWLINE_xXPatients must provide study specific informed consent prior to study entryXx_NEWLINE_xXINCLUSION CRITERIA FOR THIRD-LINE THERAPY: Subject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the IRB, prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXSigned informed consent/authorization is obtained prior to conducting any study-specific screening procedures.Xx_NEWLINE_xXProvide written informed consent prior to any study-specific screening proceduresXx_NEWLINE_xXSigned and dated written informed consent obtained prior to any study-specific evaluation.Xx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatients must give IRB approved, study specific, informed consent.Xx_NEWLINE_xXWritten informed consent obtained prior to any study-specific procedures not considered part of routine medical care.Xx_NEWLINE_xXProvided written informed consent prior to any study-specific procedures.Xx_NEWLINE_xXSigned written informed consent granted prior to initiation of any study-specific procedures.Xx_NEWLINE_xXWritten informed consent obtained prior to any study-specific procedures not considered part of routine medical careXx_NEWLINE_xXWritten informed consent obtained prior to any study-specific procedures not considered part of routine medical careXx_NEWLINE_xXUnderstands and is willing to sign an informed consent form (ICF) prior to initiation of any study-specific procedure.Xx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of signed and dated written informed consent prior to any study-specific procedures, sampling, and analyses. If a patient declines to participate in any voluntary exploratory research and/or genetic component of the study, there will be no penalty or loss of benefit to the patient and he/she will not be excluded from other aspects of the study.Xx_NEWLINE_xXProvide signed, written informed consent prior to the initiation of any study-specific proceduresXx_NEWLINE_xXAble to provide written informed consent prior to the performance of any study-specific procedures.Xx_NEWLINE_xXPatient must sign study specific informed consent prior to study entryXx_NEWLINE_xXPatient must consent to the study and provide a signed and dated, written informed consent document prior to any study-specific procedures, sampling, or analyses.Xx_NEWLINE_xXThe patient has signed informed consent prior to initiation of any study-specific procedures or treatment.Xx_NEWLINE_xXPatients must sign a study-specific informed consent prior to study entryXx_NEWLINE_xXVoluntarily signed and dated written informed consent prior to any specific-study procedure.Xx_NEWLINE_xXPatient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXAll patients must sign study specific informed consent prior to study entryXx_NEWLINE_xXPatient must sign study specific informed consent prior to study entryXx_NEWLINE_xXProvide written informed consent prior to study-specific screening procedures, with the understanding that the patient has the right to withdraw from the study at any time, without prejudiceXx_NEWLINE_xXPatient must give study-specific informed consent on an IRB-approved consent prior to any research-related procedures or study treatment.Xx_NEWLINE_xXMust sign study-specific, IRB approved informed consent form prior to study entry. Note consent by legally authorized representative is not allowed for this trial.Xx_NEWLINE_xXThe ability to provide written informed consent prior to study specific screening procedures, with the understanding that the patient has the right to withdraw from the study at any timeXx_NEWLINE_xXPatients must sign IRB approved study specific informed consent.Xx_NEWLINE_xXSpecific medicationsXx_NEWLINE_xXProvide written informed consent prior to any study-specific screening procedures.Xx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXPatients must sign a study-specific informed consent form prior to study entryXx_NEWLINE_xXProvision of written informed consent prior to any study-specific proceduresXx_NEWLINE_xXThe patient has not signed a study-specific informed consent for this study.Xx_NEWLINE_xXSubject has provided informed consent prior to initiation of any study-specific activities/procedures;Xx_NEWLINE_xXSigned, informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXProvision of informed consent prior to any study specific procedures.Xx_NEWLINE_xXPatient must sign a study specific informed consent formXx_NEWLINE_xXHave signed an informed document prior to any study-specific procedures or treatmentXx_NEWLINE_xXThe patient or legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entry; no durable power of attorney or next of kin can provide initial consentXx_NEWLINE_xXSigned informed consent obtained prior to initiation of any study-specific procedures and treatment;Xx_NEWLINE_xXAll patients must sign a study-specific consent formXx_NEWLINE_xXAble to understand and comply with the study procedures, understand the risks involved in the study, and provide written informed consent before the first study-specific procedureXx_NEWLINE_xXSigned, informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXProvision of signed and dated, written informed consent prior to any study specific procedures, sampling and analyses; including access to all archival tumour tissue (diagnostic and/or most recent samples)Xx_NEWLINE_xXSpecific mutations:Xx_NEWLINE_xXSigned and dated PICF obtained prior to initiation of any study-specific procedure and treatment.Xx_NEWLINE_xXCapable of giving written informed consent prior to any study-specific proceduresXx_NEWLINE_xXWritten informed consent prior to beginning specific protocol procedures, including expected cooperation of the patients for the study treatment regimen and follow-up, must be obtained and documented according to the local regulatory requirementsXx_NEWLINE_xXWritten informed consent/assent prior to any study-specific proceduresXx_NEWLINE_xXPatients must provide study specific informed consent prior to study entryXx_NEWLINE_xXProvide signed and dated informed consent prior to any study specific procedures.Xx_NEWLINE_xXPatient must capable of, and provide, study specific informed consent prior to study entryXx_NEWLINE_xXPatients must have given written, signed and dated informed consent prior to registration on the study; NOTE: no study-specific screening procedures may be performed until consent has been givenXx_NEWLINE_xXSigned written informed consent granted prior to initiation of any study-specific proceduresXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXSTUDY-SPECIFIC EXCLUSIONS:Xx_NEWLINE_xXPatients must sign a study-specific consent formXx_NEWLINE_xXAbility to give written, informed consent prior to any study-specific screening procedures, with the understanding that the consent may be withdrawn by the patient at any time without prejudice.Xx_NEWLINE_xXSigned informed consent prior to the start of any study specific procedures.Xx_NEWLINE_xXSigned study-specific consent formXx_NEWLINE_xXAll patients must sign study specific informed consent prior to study entry or within 1 week of first treatment, provided other criteria were metXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXPatient signs study specific informed consent prior to study enrollmentXx_NEWLINE_xXAbility to understand and willingness to sign a study-specific informed consent prior to study entryXx_NEWLINE_xXDid the patient provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must be able to provide study specific informed consent prior to study entryXx_NEWLINE_xXSigned informed consent prior to the start of any study specific procedures.Xx_NEWLINE_xXSTUDY-SPECIFIC EXCLUSIONS:Xx_NEWLINE_xXAvailable multivirus-specific VSTsXx_NEWLINE_xXPatient must be able to provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must sign study specific informed consent prior to study entryXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXCapable of understanding the informed consent and complying with the protocol and signed the informed consent document prior to any study-specific screening procedures or evaluations being performedXx_NEWLINE_xXSigned informed consent prior to initiation of any study-specific procedure or treatmentXx_NEWLINE_xXPatient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXSubject must sign a study specific informed consent prior to study entryXx_NEWLINE_xXMust sign study-specific, IRB approved informed consent form prior to study entry. Note consent by legally authorized representative is not allowed for this trial.Xx_NEWLINE_xXSigned study-specific informed consent prior to study entryXx_NEWLINE_xXWritten informed consent prior to any study-specific screening procedures with the understanding that the patient may withdraw consent at any time without prejudiceXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject‘s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXAdult subjects ?18 years of age who are able to understand study procedures, comply with them, and provide written informed consent before any study-specific procedure.Xx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXSigned study-specific informed consent form prior to study entryXx_NEWLINE_xXSigned study-specific consent form prior to registrationXx_NEWLINE_xXPatient is able to give and sign study specific informed consentXx_NEWLINE_xXSigned study-specific informed consent prior to study entryXx_NEWLINE_xXSigned and dated written ICF by the patient or legally acceptable representative prior to any study-specific proceduresXx_NEWLINE_xXPatients must give study specific informed consent prior to enrollmentXx_NEWLINE_xXPatient or legally acceptable representative has granted written informed consent before any study specific procedures (including special Screening tests) are performedXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject's routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xX101 Subject has provided informed consent prior to initiation of any study-specific activities/procedures OR subject's legally acceptable representative has provided informed consent prior to any study-specific activities/procedures being initiated when the subject has any kind of condition that, in the opinion of the investigator, may compromise the ability of the subject to give written informed consent.Xx_NEWLINE_xXProvision of informed consent prior to any study specific procedures.Xx_NEWLINE_xXMust be willing to provide informed consent prior to any study specific proceduresXx_NEWLINE_xXPatient must sign study specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study specific procedures.Xx_NEWLINE_xXAbility to sign informed consent form; informed consent form for this study must be signed prior to the performance of any study-specific procedures and initiation of any study therapyXx_NEWLINE_xXSigned informed consent prior to initiation of any study?specific procedure or treatment, including consent to provide blood samples for correlative studies and to obtain a tumor biopsy during the studyXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study registrationXx_NEWLINE_xXAdult subjects ?18 years of age who are able to understand and comply with study procedures, and provide written informed consent before any study-specific procedure.Xx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to step 1 registrationXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entry, including consent for mandatory tumor tissue, serum, and blood submission for immune correlatives (all patients) and p16 analysis (oropharyngeal cases only)Xx_NEWLINE_xXPatient must have provided study specific informed consent prior to study entryXx_NEWLINE_xXMust sign study-specific consent formXx_NEWLINE_xXWritten consent on an IRB/IEC-approved Informed Consent Form (ICF) prior to any study\n             specific evaluationXx_NEWLINE_xXAll patients must be informed of the investigational nature of this study and be willing to provide written informed consent in accordance with Institutional guidelines and good clinical practice (GCP) indicating that they understand the purpose of and procedures required for the study and are willing to participate prior to the beginning of any specific study proceduresXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entry, including consent for mandatory submission of tissue for required, central p16 reviewXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXProvision of fully informed consent prior to any study specific proceduresXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign study specific informed consentXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study-specific informed consent prior to study registrationXx_NEWLINE_xXThe patient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign a study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXAble to understand and comply with the protocol and study procedures, understand the risks involved in the study, and provide written informed consent before any study-specific procedure is performed.Xx_NEWLINE_xXThe patient has signed informed consent prior to initiation of any study-specific procedures or treatment.Xx_NEWLINE_xXThe patient has signed informed consent prior to initiation of any study-specific procedures or treatment.Xx_NEWLINE_xXPatients must sign study specific informed consent prior to study entryXx_NEWLINE_xXProvision of signed and dated, written informed consent prior to any study-specific procedures, sampling and analyses.Xx_NEWLINE_xXSigned study-specific consent form prior to registrationXx_NEWLINE_xXPatients must provide study specific informed consent prior to study entry, including consent for mandatory tissue submission for EGFR and for oropharyngeal patients, HPV analysesXx_NEWLINE_xXWritten informed consent must be obtained and documented according to the local regulatory requirements prior to beginning specific protocol procedures;Xx_NEWLINE_xXSigned written informed consent before performance of study-specific procedures or assessments and must be willing to comply with treatment and follow upXx_NEWLINE_xXSubject has provided informed consent prior to initiation of any study-specific activities/proceduresXx_NEWLINE_xXPatients must sign a study-specific consent form prior to study entryXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to step 1 registrationXx_NEWLINE_xXVoluntary written informed consent of the patient (both to participate in the study and to provide biopsy samples) obtained before any study-specific procedure.Xx_NEWLINE_xXSigned informed consent obtained prior to initiation of any study-specific procedures and treatment as confirmation of the patient’s awareness and willingness to comply with the study requirements (inclusive of 2 biopsies, one at baseline and if they qualify, one pre-randomization for part 2B)Xx_NEWLINE_xXSigned informed consent prior to any protocol-specific proceduresXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign a study-specific consent formXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXSigned study-specific consent form prior to registrationXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must capable of and provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXThe patient has signed informed consent prior to initiation of any study-specific procedures or treatment.Xx_NEWLINE_xXSigned, written informed consent by subject or legal representative prior to any trial-specific screening procedureXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXAvailable for the duration of the study and are willing to follow study-specific procedures.Xx_NEWLINE_xXProvided informed consent prior to initiation of any study-specific activities/proceduresXx_NEWLINE_xXPatients must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to adhere with treatment and follow-upXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must be willing and able to comply with the protocol and provide written informed consent prior to study specific screening proceduresXx_NEWLINE_xXProvision of informed consent prior to any study specific procedures, sampling, and analysis.Xx_NEWLINE_xXMust provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study specific procedures, sampling and analyses.Xx_NEWLINE_xXPatient must sign a study-specific consent form prior to registrationXx_NEWLINE_xXSigned, informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXProvision of signed and dated written informed consent prior to any study specific procedures.Xx_NEWLINE_xXPatients must provide written informed consent prior to performance of study-specific procedures or assessments and must be willing to comply with treatment and follow-upXx_NEWLINE_xXThe subject must provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of signed, written and dated informed consent prior to any study specific proceduresXx_NEWLINE_xXSigned, informed consent must be obtained prior to any study specific procedures.Xx_NEWLINE_xXWritten informed consent granted prior to initiation of any study-specific screening procedures, given with the understanding that the patient has the right to withdraw from the study at any time, without prejudiceXx_NEWLINE_xXSubjects must provide written informed consent within one month prior to performance of study-specific procedures or assessments and must be willing to comply with treatment and follow up\r\n* Note: informed consent will be obtained after establishing the diagnosis of high risk, localized prostate cancer, and may be obtained prior to start of the specified screening window\r\n* Note: procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study such as bone scan) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXSubjects willing and able to comply with all aspects of the protocol for the duration of the study and provide written informed consent before any study-specific screening procedures are performed, with the understanding that the subject may withdraw consent at any time without prejudiceXx_NEWLINE_xXProvision of signed and dated, written informed consent prior to any study specific procedures, sampling and analysesXx_NEWLINE_xXProvision of signed, written and dated informed consent prior to any study specific proceduresXx_NEWLINE_xXPatient must be able to provide study-specific informed consent prior to study entryXx_NEWLINE_xXSigned informed consent prior to the start of any study specific procedures.Xx_NEWLINE_xXPatients must sign a study-specific informed consent formXx_NEWLINE_xXPatient or designated individuals with durable medical power of attorney must give written informed consent prior to any study-specific procedures being implementedXx_NEWLINE_xXSigned, informed consent must be obtained prior to any study specific procedures.Xx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXPatients must sign a study-specific consent formXx_NEWLINE_xXPatients must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to adhere with treatment and follow-upXx_NEWLINE_xXInformed consent must be obtained in writing for all patients prior to performing study/screening procedures and prior to registration into the studyXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study specific procedures or assessments, and must be willing to comply with treatment and follow up \r\n* Procedures conducted as a part of routine clinical management of the subject (e.g., blood count, imaging study) and obtained prior to signed informed consent may be utilized for screening or baseline purposes provided these tests are obtained as specified in the protocol)Xx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXPatients must provide study-specific informed consent prior to study entryXx_NEWLINE_xXHave given written informed consent prior to any study-specific proceduresXx_NEWLINE_xXSubjects willing and able to comply with the study protocol for the duration of the study and provide written informed consent prior to any study-specific screening procedures with the understanding that the subject may withdraw consent at any time without prejudice.Xx_NEWLINE_xXHave given written informed consent prior to any study-specific proceduresXx_NEWLINE_xXA signed study specific consent form is requiredXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXEXPANSION COHORT ONLY: Subjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocolXx_NEWLINE_xXSigned written informed consent granted prior to initiation of any study-specific proceduresXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of written signed informed consent prior to any study specific procedures;Xx_NEWLINE_xXHave signed an informed document prior to any study-specific procedures or treatmentXx_NEWLINE_xXSigned study-specific informed consent prior to registrationXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign a study-specific informed consent form prior to treatmentXx_NEWLINE_xXWritten consent on an IRB/IEC-approved Informed Consent Form (ICF) prior to any study-specific evaluationXx_NEWLINE_xXWritten informed consent before any study-specific procedure is performedXx_NEWLINE_xXPatient is willing to sign study specific informed consentXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study specific proceduresXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-upXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow upXx_NEWLINE_xXAble to provide written informed consent prior to any study specific screening procedures with the understanding that the patient has the right to withdraw from the study at any time, for any reason without prejudiceXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entry, including consent for mandatory screening of tissueXx_NEWLINE_xXPatients must provide study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign a study-specific informed consent form prior to study entryXx_NEWLINE_xXThe patient must sign specific informed consent prior to study entryXx_NEWLINE_xXInformed consent given prior to study-specific screening proceduresXx_NEWLINE_xXHave signed written informed consent prior to the initiation of any study-specific proceduresXx_NEWLINE_xXPatients must be capable of providing informed consent and must be willing to provide written informed consent prior to the start of any study-specific procedures.Xx_NEWLINE_xXProvide written informed consent prior to any study-specific proceduresXx_NEWLINE_xXA signed informed consent must be obtained prior to any study-specific procedures.Xx_NEWLINE_xXWritten informed consent prior to completing any study-specific procedureXx_NEWLINE_xXAble to understand the study procedures and agree to participate in the study by providing written informed consent Cohort Specific Inclusion Criteria:Xx_NEWLINE_xXSigned written informed consent from either the subject, or their legally acceptable representative if the subject is incapable of giving their own consent, prior to performing any study-specific tests or procedures.Xx_NEWLINE_xXThe patient must provide study specific informed consent prior to study entryXx_NEWLINE_xXGive written informed consent prior to any study-specific procedures.Xx_NEWLINE_xXWilling and able to sign a written informed consent; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXProvision of informed consent prior to any study-related proceduresXx_NEWLINE_xXThe patient or their legally acceptable representative must be capable of giving written informed consent prior to performing any study-specific tests or procedures.Xx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocol; Note: it is not necessary that informed consent be obtained within the protocol-specified screening windowXx_NEWLINE_xXWritten informed consent has been obtained prior to the performance of any protocol-specific procedure.Xx_NEWLINE_xXAbility to understand and to sign an informed consent form; a signed informed consent must be obtained prior to any study specific proceduresXx_NEWLINE_xXWritten informed consent has been obtained prior to the performance of any protocol-specific procedure.Xx_NEWLINE_xXBefore any study-specific procedure is performed, the appropriate written informed consent must be obtainedXx_NEWLINE_xXMust give study specific informed consent prior to enrollment. For re-administration, patients must be re-consented.Xx_NEWLINE_xXWritten informed consent prior to any study specific screening procedures with the understanding that the patient may withdraw consent at any time without prejudiceXx_NEWLINE_xXPatient is able to give and sign study specific informed consentXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXThe patient must provide study-specific informed consent prior to study entry/screeningXx_NEWLINE_xXThe patient or a legally authorized representative must provide study-specific informed consent prior to study entryXx_NEWLINE_xX102 Subject or subject's legally acceptable representative has provided informed consent/assent prior to initiation of any study-specific activities/procedures.Xx_NEWLINE_xXSigned and dated informed consent form (by the patient or a legally acceptable representative as per the local regulations) obtained prior to initiation of any study-specific procedure and treatment.Xx_NEWLINE_xXPatient must provide study specific informed consent prior to study entry.Xx_NEWLINE_xXPatients must sign a study-specific consent formXx_NEWLINE_xXSubject must sign a study specific informed consent prior to study entryXx_NEWLINE_xXPatients must provide study specific informed consent prior to study entryXx_NEWLINE_xXProvision of informed consent prior to any study-related proceduresXx_NEWLINE_xXPatients must sign a study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must provide study-specific informed consent prior to registrationXx_NEWLINE_xXSubject is capable of understanding and willing to provide a signed and dated written voluntary informed consent before any protocol specific procedures are performedXx_NEWLINE_xXPatients must provide study specific informed consent prior to study entryXx_NEWLINE_xXWritten informed consent before any study-specific procedure is performedXx_NEWLINE_xXSubjects must give written informed consent to participate in study. Consent must be obtained prior to the performance of any study-specific, non-institutional standard procedures. A copy of the signed informed consent will be retained in the subject's chart.Xx_NEWLINE_xXPatients must provide study-specific informed consent prior to study entryXx_NEWLINE_xXBefore any study-specific procedure, the appropriate written informed consent must be obtained from the subject or a legally accepted representative.Xx_NEWLINE_xXPatient must be capable to read and speak English and provide study specific informed consent prior to study entryXx_NEWLINE_xXPatients must sign a study-specific consent formXx_NEWLINE_xXSigned a study-specific informed consent prior to study entryXx_NEWLINE_xXProvision of written informed consent and assent, when applicable, for tumor resection, stereotactic surgery, tumor biopsy, sample collection, and/or treatment with study drug prior to undergoing any study-specific proceduresXx_NEWLINE_xXSigned study-specific informed consent prior to registrationXx_NEWLINE_xXDocumented, signed, dated informed consent obtained prior to any study specific procedures being performedXx_NEWLINE_xXSPECIFIC TO STUDY PART #1Xx_NEWLINE_xXSPECIFIC TO STUDY PART #2Xx_NEWLINE_xXPatient must sign study-specific informed consent prior to study entryXx_NEWLINE_xXSigned, specific informed consent prior to study entryXx_NEWLINE_xXPatient or the patient’s legally authorized representative must provide written informed consent prior to registration and any study-related proceduresXx_NEWLINE_xXProvision of informed consent prior to any study-related proceduresXx_NEWLINE_xXSubjects must provide written informed consent prior to performance of study-specific procedures or assessments, and must be willing to comply with treatment and follow-up; procedures conducted as part of the subject’s routine clinical management (e.g., blood count, imaging study) and obtained prior to signing of informed consent may be utilized for screening or baseline purposes provided these procedures are conducted as specified in the protocol \r\n* Note: it is not necessary that informed consent be obtained within the protocol specified screening windowXx_NEWLINE_xXPatient must sign study-specific informed consent prior to study entryXx_NEWLINE_xXWomen competent to sign study specific written informed consentXx_NEWLINE_xXPatient, or the patient’s legally acceptable representative, must provide a signed and dated written informed consent prior to registration and any study-related proceduresXx_NEWLINE_xXPatients competent to sign study specific informed consentXx_NEWLINE_xXSigned, specific informed consent prior to study entryXx_NEWLINE_xXValid written informed consent signed by the patient prior to any study-specific proceduresXx_NEWLINE_xXSubject must sign a study specific informed consent prior to study entryXx_NEWLINE_xXPatient or the patient’s legally acceptable representative must provide written informed consent prior to registration and any study-related proceduresXx_NEWLINE_xXProvide written informed consent prior to any study-specific screening proceduresXx_NEWLINE_xXProvision of signed and dated written informed consent prior to any study specific procedures, sampling analysisXx_NEWLINE_xXHas voluntarily consented to participate and provided written informed consent prior to any protocol-specific proceduresXx_NEWLINE_xXThe patient must have capacity to be able to sign a study-specific informed consent prior to study entryXx_NEWLINE_xXPatients must be capable to read and speak English and provide study specific informed consent prior to study entryXx_NEWLINE_xXPatient must provide study specific informed consent prior to study entryXx_NEWLINE_xXUnderstand and provide written informed consent prior to initiation of any study-specific procedures.Xx_NEWLINE_xXVoluntarily signed and dated written informed consent prior to any specific study procedure.Xx_NEWLINE_xXWritten informed consent obtained prior any study-specific procedure (patient or parent(s) or legal representative)Xx_NEWLINE_xXSigned and dated informed consent document obtained prior to initiation of any study-specific procedure and treatment (by the subject or a legally acceptable representative as per the local regulations).Xx_NEWLINE_xXSigned informed consent prior to any protocol-specific proceduresXx_NEWLINE_xX