Total bilirubin < 1.5 x upper limit of normal (ULN) if no liver metastases or =< 3 times ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinaemia) or liver metastases within 4 weeks before randomizationXx_NEWLINE_xXBilirubin =< 1.5 times normal 14 days prior to study entryXx_NEWLINE_xXBilirubin < 1.5 times institutional upper limit of normal, within 21 days prior to study entryXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin equal to or less than 1.5 times the ULNXx_NEWLINE_xXTotal bilirubin =< 2 mg/dL or =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (x ULN).Xx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin 1.5 times upper limit of normalXx_NEWLINE_xXPT ? 1.5 times institutional ULNXx_NEWLINE_xXPTT ? 1.5 times institutional ULNXx_NEWLINE_xXBilirubin ? 1.5 times upper limit of normal (x ULN); if liver metastases are present, then ? 2 x ULN is allowed. Criteria does not apply to subjects with Gilbert's syndrome diagnosed as per institutional guidelines.Xx_NEWLINE_xXParticipants must have total bilirubin less than or equal to 1.5 times the upper limit of normal (ULN), and aspartate aminotransferase and alanine aminotransferase less than or equal to 2.5 times ULN.Xx_NEWLINE_xXTotal bilirubin < 1 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 2.5 times upper limit of normal ANDXx_NEWLINE_xXTotal or direct bilirubin ? 1.5 times upper limit of normal (x ULN); does not apply to subjects with Gilbert's syndrome diagnosed as per institutional guidelines.Xx_NEWLINE_xXWithin 30 days prior to enrollment: Total bilirubin equal to or less than 1.5 times the ULNXx_NEWLINE_xXtotal bilirubin ? 3 times the upper limit of normal (ULN)Xx_NEWLINE_xXSerum bilirubin ? institutional 1.5 times upper limit of normal (ULN) (OR for patients with documented Gilbert syndrome, total bilirubin ? 3.0 times ULN with direct bilirubin ? ULN)Xx_NEWLINE_xXTotal serum bilirubin ?1.5 times ULNXx_NEWLINE_xXHepatic: Bilirubin ?1.5 times upper limits of normal (ULN), alanine aminotransferase (ALT) ? 3.0 times ULN.Xx_NEWLINE_xXSerum total bilirubin =< 2.0 times the upper limit of normalXx_NEWLINE_xXBilirubin < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin less than 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 1.5 times the upper limit of normal (ULN) if no liver metastases or < 3 times the ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinemia) or liver metastasesXx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normal (ULN) OR direct bilirubin =< the normal in subjects with total bilirubin > 1.5 times the ULNXx_NEWLINE_xXTotal bilirubin ? 2 times upper limit of normal (ULN). (Participants with known Gilbert's disease who has serum bilirubin ? 3 × ULN may be enrolled).Xx_NEWLINE_xXTotal bilirubin ?1.5 times the upper limit of normal (ULN) except for unconjugated hyperbilirubinemia of Gilbert's syndrome;Xx_NEWLINE_xXDirect bilirubin within =< 1.5 times the institutional upper limit of normal (ULN); for patients with known Gilbert syndrome, or if the elevation is believed to be leukemia related, the cut-off of =< 3.0 times the institutional ULN is allowableXx_NEWLINE_xXTotal bilirubin < 1.5 times the upper limit of normal (ULN) if no liver metastases or < 3 times the ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinemia) or liver metastasesXx_NEWLINE_xXTotal serum bilirubin > 1.5 times ULNXx_NEWLINE_xXINCLUSION - TREATMENT: Bilirubin less than 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times ULN before starting therapyXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal for age and documented within 14 days prior to registration and within 14 days prior to the start of treatmentXx_NEWLINE_xXDocumented within 14 days of registration: Total bilirubin < 1.5 times upper limit of normal for ageXx_NEWLINE_xXBilirubin < 2.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXAlanine aminotransferase > 2.5 times the upper limit of normal (ULN) if no demonstrable liver metastases or > 5 times the ULN in the presence of liver metastases.Xx_NEWLINE_xXTotal bilirubin > 1.5 times the ULN if no liver metastases or > 3 times the ULN in the presence of documented Gilbert's Syndrome (unconjugated hyperbilirubinemia) or liver metastases.Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal\r\n* If transaminase elevation and/or bilirubin elevation is attributed to the presence of liver metastases, a total bilirubin =< 2.5 times the upper limit of normal and an aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 times the upper limit of normal are permissible; patients with an elevated bilirubin level that is attributed to an inherited disorder, such as Gilbert’s disease, may be enrolled at the discretion of the principal investigatorXx_NEWLINE_xXAST/ALT =< 1.5 times upper limit of normal\r\n* If transaminase elevation and/or bilirubin elevation is attributed to the presence of liver metastases, a total bilirubin =< 2.5 times the upper limit of normal and an AST and ALT =< 2.5 times the upper limit of normal are permissible; patients with an elevated bilirubin level that is attributed to an inherited disorder, such as Gilbert’s disease, may be enrolled at the discretion of the principal investigatorXx_NEWLINE_xXTotal bilirubin >1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTREATMENT INCLUSION: Bilirubin 1.5 times or less than the upper limit of normalXx_NEWLINE_xXTotal or direct bilirubin ? 2 times upper limit of normal (x ULN); does not apply to subjects with Gilbert's syndrome diagnosed as per institutional guidelines.Xx_NEWLINE_xXTotal bilirubin >1.5 times ULNXx_NEWLINE_xXtotal bilirubin < 1.5 X (ULN) ; alanine aminotransferase (ALT), aspartate transaminase (AST) ? 2.5 times the upper limit of normal (ULN) if no liver involvement or ? 5 times the upper limit of normal with liver involvement.Xx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of institutional normalXx_NEWLINE_xXPHASE I: Total bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXPHASE IB: Total bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXINCLUSION CRITERIA FOR STRATUM C: Total bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of institutional normal (ULN) for ageXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal except for known conjugation diseases such as Gilbert’s; direct bilirubin is not an inclusion criteriaXx_NEWLINE_xXTotal bilirubin =< 2.5 times upper limit of normalXx_NEWLINE_xXtotal bilirubin ? 2 times the upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin ? 1.5 times the upper limit of normal (ULN),Xx_NEWLINE_xXTotal bilirubin (TBL) > 2.5 times the upper limit of normal at the screening visitXx_NEWLINE_xXTotal bilirubin < 3.0 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin ? 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 2.0 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of the reference rangeXx_NEWLINE_xXTREATMENT WITH SJCAR19: Total bilirubin =< 3 times the upper limit of normal for age, except in subjects with Gilbert’s syndromeXx_NEWLINE_xXTotal serum bilirubin =< 1.5 times upper limit of normal (ULN).Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN).Xx_NEWLINE_xXSerum bilirubin >= 1.5 x upper limit of normal (ULN), patients with Gilbert’s syndrome and a total bilirubin of < 3 times ULN are permitted)Xx_NEWLINE_xXHas liver fibrosis either determined by imaging or laboratory testing (i.e. total serum bilirubin > 1.5 times ULN, AST and ALT > 2.5 times ULN, INR > 1.5 times ULN, albumin < 2.5 mg/dl)Xx_NEWLINE_xXBilirubin greater than 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin less than 2 mg/dL or 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin ? 2.0 times the upper limit of normal (ULN) of each institution with the following exception: patients with Gilbert Disease serum bilirubin > 3 x ULN.Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normal.Xx_NEWLINE_xXTotal bilirubin < 1.5 times ULN if no liver metastases or < 3 times ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinaemia) or liver metastases obtained =< 14 days prior to study initiationXx_NEWLINE_xXSerum bilirubin =< 1.5 times upper-limit of normal (ULN) (measured within 28 days of registration)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (unless bilirubin rise is due to Gilbert’s syndrome or of non-hepatic origin)Xx_NEWLINE_xXTotal bilirubin >1.5 times ULN if no liver metastases or 3 times ULN in the presence of liver metastases or documented Gilbert's Syndrome (unconjugated hyperbilirubinaemia)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin > 1.5 times the upper limit of normal (ULN) if no demonstrable liver metastases or > 3 times ULN in the presence of documented Gilbert’s syndrome or liver metastasesXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (x ULN).Xx_NEWLINE_xXWithin two weeks prior to enrollment: Total bilirubin =< 1.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal for age, within 14 days of registration and within 7 days of the start of treatmentXx_NEWLINE_xXTotal bilirubin (Tbili) > 1.5 times the upper limit of normal at the screening visitXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal (ULN) unless bilirubin rise is due to Gilbert’s syndrome or of non-hepatic originXx_NEWLINE_xXBilirubin ?1.5 times the upper limit of normal (ULN) unless due to Gilbert SyndromeXx_NEWLINE_xXTotal bilirubin < 2.5 times the upper limits of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normal for ageXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN) for the institution (for patients with known Gilbert's disease: bilirubin =< 3 x ULN) within 14 days of study registrationXx_NEWLINE_xXSerum bilirubin =< 1.5 times upper limit of normal (prior to biopsy)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin > 2 times the upper limit of normal OR in patients with Gilbert’s syndrome, a total bilirubin > 3.0Xx_NEWLINE_xXTotal bilirubin ? 3 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of the institutional normal valuesXx_NEWLINE_xXBilirubin < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal serum bilirubin ? 1.5 times the ULNXx_NEWLINE_xXSTUDY TREATMENT: Serum bilirubin value less than 1.5 times the upper limit of the normal rangeXx_NEWLINE_xXSerum bilirubin > 1.5 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome: total bilirubin of > 3 x ULN) at the time of screeningXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin > 1.5 times the upper limit of the normal range (ULN)Xx_NEWLINE_xX• Bilirubin ? 1.5 times institutional ULN; does not apply to patients diagnosed with Gilbert's syndrome.Xx_NEWLINE_xXTotal bilirubin greater than 2.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normal (ULN) (or =< 3 times ULN in case of liver metastasis or Gilbert syndrome)Xx_NEWLINE_xXHave serum aspartate aminotransferase (AST) >5 times upper limit of normal (ULN) at screening, or serum alanine aminotransferase (ALT) >5 times ULN at screening, or total bilirubin >=3.0 x ULN at screening (except for documented Gilbert's syndrome), as analyzed by local or central lab.Xx_NEWLINE_xXTotal bilirubin </=2 times the ULNXx_NEWLINE_xXTransaminase levels </=2.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal serum bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of (institutional/central) normal (patients with Gilbert’s syndrome total bilirubin must be =< 4 times institutional upper limit of normal)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) at the screening visit unless an alternate nonmalignant etiology exists (e.g., Gilbert’s disease)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) at the screening visit unless an alternate nonmalignant etiology exists (eg, Gilbert’s disease)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (x ULN) (=< 3 x ULN if considered to be due to leukemic involvement or Gilbert’s syndrome)Xx_NEWLINE_xXBilirubin =< 1.5 times upper limits of normal (ULN)Xx_NEWLINE_xXBilirubin =< 3 times upper limit of normal (CTCAE grade 2 baseline)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin ?1.5 times ULN; andXx_NEWLINE_xXBilirubin (total) > 1.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 2 times the upper limit of normal (ULN) (or =< 3.0 x ULN if deemed to be elevated due to Gilbert’s disease or leukemia)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normal (ULN) (except subjects with Gilbert syndrome, who can have total bilirubin < 3.0 mg/dL)Xx_NEWLINE_xXCompleted within 60 days of surgery: Total bilirubin < 1.5 times the upper limit of institutional normal valueXx_NEWLINE_xXSerum bilirubin =< 3 times the upper limit of normal (ULN) (within 14 days prior to registration)Xx_NEWLINE_xXBilirubin =< 3 times the upper limit of normal for ageXx_NEWLINE_xXTotal bilirubin ?1.5 times ULN; andXx_NEWLINE_xXTotal bilirubin =< 2 mg/dL; serum transaminases less than two times the institutional upper limit of normal (< 2 x upper limit of normal [ULN])Xx_NEWLINE_xXAlanine aminotransferase > 2.5 times the upper limit of normal (ULN) if no demonstrable liver metastases or > 5 times ULN in the presence of liver metastasesXx_NEWLINE_xXTotal bilirubin > 1.5 times ULN if no liver metastases or > 3 times ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinemia) or liver metastasesXx_NEWLINE_xXPRIOR TO CELL PROCUREMENT: Bilirubin ? 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXPRIOR TO INFUSION OF ATLCAR.CD30 CELLS: Bilirubin ? 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin ? 2 times the upper limit of normal (ULN) unless due to Gilbert's diseaseXx_NEWLINE_xXSerum total bilirubin > 1.5 times the upper limit of normal (ULN);Xx_NEWLINE_xXBilirubin ? 2 times upper limit of normalXx_NEWLINE_xXWithin 14 days of first dose of study drug administration: Total bilirubin =< 1.5 times the institutional upper limit of normal (ULN) (or =< 3 times ULN in case of liver metastasis)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin > 1.5 times upper limit of normal (ULN) unless an alternate nonmalignant etiology exists (e.g., Gilbert's disease)Xx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin of =< 1.5 times upper limit of normal (exception is made for patients with Gilbert’s syndrome who may be considered eligible if total bilirubin is < 3 times upper limit of normal)Xx_NEWLINE_xXTotal bilirubin < 1.5 times ULN unless due to Gilbert's diseaseXx_NEWLINE_xXTotal bilirubin =< 2 times upper limit of normal (x ULN) (3 x ULN if considered to be due to leukemia involvement or Gilbert’s syndrome)Xx_NEWLINE_xXbilirubin less than or equal 1.5 times the upper limit of normal (ULN).Xx_NEWLINE_xXTotal serum bilirubin =< 1.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 2 times upper limit of normal (x ULN) (=< 3 x ULN if considered to be due to leukemic involvement or Gilbert’s syndrome)Xx_NEWLINE_xXEXCLUSION CRITERIA FOR ENROLLMENT: Total bilirubin > 3 times the ULNXx_NEWLINE_xXEXCLUSION CRITERIA FOR ADDITIONAL PTCy-MILs INFUSION AT RELAPSE: Total bilirubin > 3 times the upper limit of normal (ULN)Xx_NEWLINE_xXWithin 21 days prior to course 1 day 1 (C1D1): Total bilirubin < 2 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin < 2 times upper limit of normal (unless due to Gilbert’s syndrome), performed within 28 days prior to registrationXx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN) (to be performed within 7 days prior to start of study treatment)Xx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN); this value must be obtained within two weeks before protocol entryXx_NEWLINE_xXBilirubin < 2.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum bilirubin < 1.5 times ULNXx_NEWLINE_xXTotal bilirubin < 2.0 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 3 times the upper limit of normal if patient had recent biliary stenting and a falling trend in bilirubin is demonstrated such that capecitabine treatment is deemed feasible per the treating medical oncologist, total bilirubin =< 1.5 times the upper limit of normal if no biliary stenting was doneXx_NEWLINE_xXtotal bilirubin 1.5 times greater than the ULN, except if related to ALL/LBL,Xx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin less than 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin =< 3 times the upper limit of normal for ageXx_NEWLINE_xXTotal bilirubin =< 2 times the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine and total bilirubin ? 1.5 times ULNXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of the normal range (ULN)Xx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin < 2.0 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times ULNXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN); this value must be obtained within four weeks before protocol entryXx_NEWLINE_xXBilirubin < 2 times ULN (performed within 14 days prior to registration)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin > 1.5 times ULN if no liver metastases or > 3 times ULN in the presence of documented Gilbert’s syndrome (unconjugated hyperbilirubinemia) or liver metastasesXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal for ageXx_NEWLINE_xXPatients with total bilirubin >= 2.0 times upper limit of normal unless felt to be related the underlying leukemia by the treating physician or hemolysis or Gilbert's diseaseXx_NEWLINE_xXBilirubin 1.5 times or less than the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal rangeXx_NEWLINE_xXAST and ALT < 5 times ULN; ALP < 5 times ULN; Bilirubin ? 1.5 times ULN; Creatinine ? 1.5 times ULN and eGFR ? 50.Xx_NEWLINE_xXBilirubin < 4 times the upper limit of institutional normalXx_NEWLINE_xXSerum bilirubin < 1.5 times the upper limit of normal (ULN); unless due to Gilbert’s syndrome (in which < 2 times ULN acceptable)Xx_NEWLINE_xXTotal bilirubin =< 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXBilirubin > 1.5 times ULNXx_NEWLINE_xXBilirubin =< 1.5 times (x) upper limit of normal (ULN) (except patients with Gilbert’s syndrome, who must have a total bilirubin less than 3.0 mg/dL)Xx_NEWLINE_xXAdequate liver function defined by a bilirubin value ?2 times the upper limit of normal (ULN), and transaminases (AST and ALT) values ?2.5 times ULNXx_NEWLINE_xXTotal bilirubin <1.5 times ULNXx_NEWLINE_xXTotal bilirubin ? 2 times the upper limit of normal (ULN) unless due to Gilbert's diseaseXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) within 28 days prior to registration.Xx_NEWLINE_xXBilirubin < 3 times the upper limit of institutional normalXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXSerum total bilirubin and liver enzymes are 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXObtained =< 7 days prior to registration: Total bilirubin =< 1.5 times the upper limit of normal (ULN) except for unconjugated hyperbilirubinemia of Gilbert’s syndromeXx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin level >= 1.5 times the upper limit of normal (ULN) (except patients with Gilbert syndrome, who are excluded if total bilirubin >= 3 times ULN), orXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) for ageXx_NEWLINE_xXTotal bilirubin within =< 1.5 times the upper limit of normal (ULN) institutional limitsXx_NEWLINE_xXSerum bilirubin greater than 3 times the upper limit of normal, unless attributed to Gilbert’s syndromeXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of institutional normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXSerum bilirubin < 1.5 times the institutional upper limit of normalXx_NEWLINE_xXTotal serum bilirubin of less than 3 times the upper limit of normalXx_NEWLINE_xXBilirubin less than 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 2 mg/dL or =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXPHASE II: Total bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin less than 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 1.5 times the institutional upper limit of normal (ULN); subjects with Gilbert’s syndrome and total bilirubin >= 1.5 times the upper limit of normal are eligible to participateXx_NEWLINE_xXTotal bilirubin < 1.5 times the upper limit of normal (ULN) unless due to Gilbert’s disease or hemolysisXx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal serum/plasma bilirubin ?1.5 times the upper limit of normal (ULN).Xx_NEWLINE_xXBilirubin ? 1.5 times upper limit of normal (CTCAE Grade 2 baseline)Xx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin =< 1.5 times the institutional limit of normalXx_NEWLINE_xXTotal bilirubin less =< to 1 times ULNXx_NEWLINE_xXTotal bilirubin ? 1.5 times the upper limit of normal;Xx_NEWLINE_xXTotal serum/plasma bilirubin ?1.5 times ULN.Xx_NEWLINE_xXTotal bilirubin ? 3 times upper limit of normal (ULN) for ageXx_NEWLINE_xXTotal bilirubin =< 2 times upper limit of normal (x ULN) (=< 3 x ULN if considered to be due to leukemic involvement or Gilbert’s syndrome)Xx_NEWLINE_xXTotal bilirubin =< 1.25 times upper limit of normalXx_NEWLINE_xXBilirubin <= 1.5 times the upper limit of normal (ULN).Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 1.5 times ULNXx_NEWLINE_xXBilirubin 1.5 times or less than the upper limit of normalXx_NEWLINE_xXTotal bilirubin within 3 times the upper limits of normalXx_NEWLINE_xXTotal bilirubin =< 2.5 times upper limit of normal; ANDXx_NEWLINE_xXTotal bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin within 1.5 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of institutional normal (ULN) for age obtained =< 7 days prior to registrationXx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN) unless due to Gilbert’s disease or hemolysisXx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXSerum bilirubin =< 1.5 times upper-limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN) unless due to Gilbert’s disease or hemolysis, then =< 3.0 times ULNXx_NEWLINE_xXBilirubin < 1.5 times ULN, unless bilirubin elevation is related to Gilbert’s syndrome for which bilirubin must be < 4 times ULNXx_NEWLINE_xXTotal bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXBilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXTotal bilirubin < 1.5 times the upper limit of normal (x ULN) for the institutionXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal unless due to Gilbert’s disease within 14 days before enrollmentXx_NEWLINE_xXTotal bilirubin < 1.5 times institutional upper normal limit (unless due to disease involvement of liver, hemolysis or a known history of Gilbert’s disease)Xx_NEWLINE_xXBilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXAST ? 2.5 times upper limit of normal (ULN) (? 5 times ULN for patients with liver metastases);Xx_NEWLINE_xXSerum total bilirubin =< 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times ULN (upper limit of normal)Xx_NEWLINE_xXTotal bilirubin > 2.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin >= 1.5 times ULNXx_NEWLINE_xXTotal bilirubin =< 1.5 x ULN (except for patients with liver metastases, ALT and/or ALT =< 5 times the upper limit of normal is accepted)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times ULN*Xx_NEWLINE_xXBilirubin =< 1.5 times (x) the institutional upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1. 5 times the institutional upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin > 1.5 times upper normal limit (unless due to chronic GVHD)Xx_NEWLINE_xXTotal bilirubin < 2.0 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN); for patients with known Gilbert’s disease, total bilirubin should be =< 3 mg/dLXx_NEWLINE_xXSerum bilirubin levels =< 1.5 times the ULN range for the laboratoryXx_NEWLINE_xXBilirubin no greater than 1.5 times ULNXx_NEWLINE_xXBilirubin < 2 times ULNXx_NEWLINE_xXTotal bilirubin =< 2 times upper limit of normalXx_NEWLINE_xXBilirubin < 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 2.5 times ULNXx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal within two weeks prior to enrollmentXx_NEWLINE_xXTotal bilirubin should be < 1.5 times ULNXx_NEWLINE_xXAmmonia < 1.5 times ULNXx_NEWLINE_xXSGOT < 2.5 times ULNXx_NEWLINE_xXTotal bilirubin within 1.5 times the upper limit of normal institutional limitsXx_NEWLINE_xXTotal bilirubin < 2.0 times the institutional Upper Limit of Normal (ULN)Xx_NEWLINE_xXBilirubin less than 6 times the upper limit of normalXx_NEWLINE_xXTotal and direct bilirubin < 1.5 times upper limit of laboratory normalXx_NEWLINE_xXHepatic Function: Bilirubin ? 1.5 times institutional normal; SGPT (ALT) < 3 times institutional normalXx_NEWLINE_xXBilirubin < 2 times the upper limit of normalXx_NEWLINE_xXBilirubin =< 1.5 times ULNXx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal (ULN), except patients with Gilbert's syndrome who must have total bilirubin of < 3 times ULNXx_NEWLINE_xXTotal bilirubin ?2 times the upper limit of normal (× ULN)Xx_NEWLINE_xXBilirubin ?2.0 times ULN, unless participant has known Gilbert's syndromeXx_NEWLINE_xXBilirubin =< 2.0 times normalXx_NEWLINE_xXBilirubin ? 2.0 times ULN, unless subject has known Gilbert's syndromeXx_NEWLINE_xXTotal bilirubin =< 2 times upper limit of normal (x ULN) (=< 3 x ULN if considered to be due to leukemic involvement or Gilbert’s syndrome)Xx_NEWLINE_xXTotal bilirubin =< 3 times the upper limit of normal unless hepatic dysfunction is related to liver involvement with diseaseXx_NEWLINE_xXTotal bilirubin ? 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times ULN and stable X 1 monthXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) institutional limits (unless Gilbert's disease)Xx_NEWLINE_xXTotal bilirubin < 1.5 times upper limit of normal (ULN) institutional limits (unless Gilbert's disease)Xx_NEWLINE_xXTotal bilirubin < 2.5 times the upper limit of normal; in patients with liver metastasis, liver function tests should be < 5 times the upper limit of normalXx_NEWLINE_xXSerum bilirubin =< 2 times ULNXx_NEWLINE_xXInadequate hepatic function (Total bilirubin > 1.5 times the institutional upper limit of normal (ULN) (except known Gilbert's syndrome); Alanine transaminase (ALT) or aspartate transaminase (AST) > 2.5 times the institutional ULN. ALT or AST up to 3 times the institutional ULN permitted if total bilirubin is normalXx_NEWLINE_xXTotal bilirubin </=1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN) for the institutionXx_NEWLINE_xXTotal bilirubin =< 1.5 times the institutional upper limit of normalXx_NEWLINE_xXPatients must have adequate hepatic function with a total bilirubin =< 1.5 times upper limit normal (ULN) within one week prior to treatmentXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (x ULN) for the institution or =< 3 mg/dl in a subject with Gilbert syndromeXx_NEWLINE_xXTotal bilirubin > 2 times upper normal limit (unless due to tumor involvement of liver or a known history of Gilbert’s disease)Xx_NEWLINE_xXRECURRENT/ PROGRESSIVE DIPG (STRATUM 1): Total bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXNON-PROGRESSED DIPG (STRATUM 2): Total bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper normal limit (UNL), except patients with Gilbert’s syndrome in whom total bilirubin must be < 3.0 mg/dLXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit normal (ULN) other than cases of Gilbert diseaseXx_NEWLINE_xXTotal bilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXBilirubin < 1.5 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin </=1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXInadequate liver function as indicated by total bilirubin >= 1.5 times the upper limit of normalXx_NEWLINE_xXBilirubin =< 3 times the upper limit of normal for ageXx_NEWLINE_xXBilirubin =< 3 times the upper limit of normal for ageXx_NEWLINE_xXBilirubin > 1.5 times the upper limit of the normal range (ULN).Xx_NEWLINE_xXDoes the subject have an ALT < 3 times the upper limit of the laboratory reference range and total bilirubin < 1.5 mg/dL?Xx_NEWLINE_xXTotal bilirubin less than 1.5 times upper limit of normal (ULN), or less than 3 times ULN at study entry in a patient with documented Gilbert’s diseaseXx_NEWLINE_xXTotal bilirubin =< 1.5 times institutional upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin ? 3 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times the upper limit of normal for ageXx_NEWLINE_xXBilirubin < 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) for ageXx_NEWLINE_xXBilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin less than or equal to 1.5 times the upper limit of normal (ULN) except for unconjugated hyperbilirubinemia of Gilbert's syndrome.Xx_NEWLINE_xXTotal bilirubin >= 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXSerum bilirubin < 1.5 times the Upper Limit of Nor-mal (ULN).Xx_NEWLINE_xXBilirubin < 1.5 times ULNXx_NEWLINE_xXSerum bilirubin < 1.5 times the Upper Limit of Nor-mal (ULN).Xx_NEWLINE_xXBilirubin < 1.5 times upper limit of normal (ULN) for ageXx_NEWLINE_xXTotal bilirubin < 1.5 times ULNXx_NEWLINE_xXTotal bilirubin < 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normalXx_NEWLINE_xXTotal bilirubin < 2 times the upper limit of normal (ULN) (except patients with Gilbert’s syndrome who must have a total bilirubin of < 3 times ULN)Xx_NEWLINE_xXTotal bilirubin < 1.5 times ULNXx_NEWLINE_xXTotal bilirubin ? 2.5 times upper limit of normal (ULN);Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (ULN) OR direct bilirubin normal (per institute standards)Xx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normalXx_NEWLINE_xXObtained within 14 days prior to initiation of treatment: Serum bilirubin < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXSerum bilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXTotal serum bilirubin < 2 times upper limit of normalXx_NEWLINE_xXElevated liver enzymes or bilirubin defined as 3 times the upper limits of normalXx_NEWLINE_xXSerum bilirubin </= 3 times upper limit of normal (x ULN)Xx_NEWLINE_xXSerum bilirubin =< 1.5 times the upper limit of normal; or total bilirubin =< 3 times the upper limit of normal with direct bilirubin within the normal range in patients with well documented Gilbert syndromeXx_NEWLINE_xXTotal bilirubin greater than 2 times upper limit of normalXx_NEWLINE_xXTotal bilirubin must be < 2.0 times the upper limit of the institutional normal range; test results must be no more than 3 months oldXx_NEWLINE_xXTotal bilirubin must be < 1.5 times the upper limit of normalXx_NEWLINE_xXBaseline direct bilirubin lower than three times the upper limit of normalXx_NEWLINE_xXMinocycline trial only: screening results for total bilirubin must be < 2 times the upper limit of normalXx_NEWLINE_xXPatient with total bilirubin three times the upper limit of normalXx_NEWLINE_xXTotal bilirubin must be < 1.5 times the upper limit of normal, as evidenced in laboratory values =< 3 months oldXx_NEWLINE_xXTotal bilirubin level greater than 3 times the ULNXx_NEWLINE_xXBilirubin < 1.5 times upper limit of normalXx_NEWLINE_xXBilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXRequired prior to infusion of ATLCAR.CD30 cells: Bilirubin =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin level =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXHas laboratory results that are outside of normal limits at screening, as follows: a) Moderate or severe liver dysfunction, as defined as: Aspartate aminotransferase (AST) > 5 times the upper limit of normal (ULN), OR Alanine aminotransferase (ALT) > 5 times the ULN, OR Serum total bilirubin >2.5 times the ULN, OR AST or ALT > 3 times ULN with total bilirubin > 2 times ULN; b) Calculated creatinine clearance <30 mL/min.Xx_NEWLINE_xXTotal bilirubin within 1.5 times the institution’s upper limit of normal (ULN)Xx_NEWLINE_xXSUB-STUDY I: Total bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXSUB-STUDY II: Total bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXSUB-STUDY III: Total bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin > 2 times the upper limit of normalXx_NEWLINE_xXTotal bilirubin > 2 times the upper limit of normalXx_NEWLINE_xXTotal serum bilirubin > 1.5 times upper limit of normal; increased serum bilirubin due to Gilbert's syndrome is permittedXx_NEWLINE_xXTotal bilirubin > 3 times the upper limit of normalXx_NEWLINE_xXBilirubin (total) less than 4.0 times below or above the upper or lower limit rangeXx_NEWLINE_xXTotal bilirubin less than 4.0 times below or above the upper or lower limit rangeXx_NEWLINE_xXBilirubin (total) =< 1.5 times upper limit normal (with exception of Gilberts syndrome)Xx_NEWLINE_xXLiver function: total bilirubin ? 1.5 times the upper limit of normal (ULN) of each institution, aspartate aminotransferase and alanine aminotransferase ? 3 times the ULN range of each institution.Xx_NEWLINE_xXTotal bilirubin > 2 times the upper limit of normalXx_NEWLINE_xXBilirubin <4.0 mg/dl, SGOT ? 1.5 times the upper limit of normalXx_NEWLINE_xXBilirubin < 2 times ULN, performed within 28 days prior to registrationXx_NEWLINE_xXPatients must have adequate hepatic and renal function as evidenced by bilirubin 2.0 times the upper limit of the normal range (ULN) or lower, alanine aminotransferase (ALT) and asparate aminotransferase (AST) 3 times the ULN or lower, serum creatinine 1.5 times the ULN or lower. Patients with nonclinically significant elevations of bilirubin up to 5.0 g/dL (85500 ?mol/L) due to known or suspected Gilbert's disease are eligible; this must be documented on the medical history page of the case report form (CRF).Xx_NEWLINE_xXTotal bilirubin ?1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXTotal bilirubin ? 1.5 times the upper limit of normal (ULN). For intrahepatic cholangiocarcinoma (IHCC) patients only, total bilirubin ? 2.5 times ULN is acceptableXx_NEWLINE_xXTotal serum/plasma bilirubin ?1.5 times ULN.Xx_NEWLINE_xXTotal bilirubin =< 1.5 times upper limit of normal (unless bilirubin rise is due to Gilbert’s syndrome or of non-hepatic origin)Xx_NEWLINE_xX