Active infection requiring systemic therapyXx_NEWLINE_xXThe subject has or had any active infection requiring systemic antibiotic, antifungal or antiviral therapy within the past 4 weeksXx_NEWLINE_xXPatients must not have an active infection requiring systemic therapy at time of registrationXx_NEWLINE_xXPatients must not have an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before registrationXx_NEWLINE_xXPatients must not have an active infection requiring systemic therapyXx_NEWLINE_xXActive systemic infection requiring parenteral antibiotic therapy; all prior infections must have resolved following optimal therapyXx_NEWLINE_xXActive infection (any infection requiring systemic treatment)Xx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic treatment or any uncontrolled infection </= 14 days prior to enrollmentXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapyXx_NEWLINE_xXHas an active systemic infectionXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas a known active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive systemic infection requiring parenteral antibiotic therapy. All prior infections must have resolved following optimal therapyXx_NEWLINE_xXActive infection (any infection requiring systemic treatment). Hepatitis B or C [HBV/HCV] is allowedXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring within 2 weeks prior to first dose of study drugXx_NEWLINE_xXHas an active infection requiring systemic therapy within 3 days of registration (NOTE: except for uncomplicated urinary tract infection [UTI])Xx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXPatient has an active infection requiring systemic therapyXx_NEWLINE_xXSAFETY RUN-IN: Active infection requiring systemic therapyXx_NEWLINE_xXRANDOMIZED PHASE II CLINICAL TRIAL: Active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXPatients who have an infection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollment are not eligibleXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXSubjects with active infection requiring antibiotic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXAn active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXActive infection (any infection requiring systemic treatment)Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapyXx_NEWLINE_xXHas an active infection requiring systemic treatmentXx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring therapy.Xx_NEWLINE_xXPatient has an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXActive infection requiring systemic therapy; NOTE: when the infection is controlled, patients are permitted for this studyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXEXCLUSION - PARTICIPANT: Active infection requiring systemic antibiotic therapy. Participants requiring systemic antibiotics for infection must have completed therapy before treatment is initiated.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study drug administrationXx_NEWLINE_xXActive infection requiring systemic therapy at the time of study treatment initiationXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXRecent infection requiring intravenous anti-infective treatment that was completed =< 14 days before enrollment; active infection requiring systemic therapyXx_NEWLINE_xXSerious, systemic infection requiring treatment ? 7 days before the first dose of study drugXx_NEWLINE_xXParticipants must not have an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection at the time of cycle 1 day 1 requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXKnown infection requiring the systemic use of, for example, an antibiotic or antiviral agentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas a clinically significant active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXactive infection requiring systemic therapy;Xx_NEWLINE_xXInfection requiring systemic intravenous antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXPatient has active infection requiring system therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXOther active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas active infection requiring systemic therapyXx_NEWLINE_xXSerious, systemic infection requiring treatment =< 7 days before the first dose of study drugXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy (apart from cutaneous infections).Xx_NEWLINE_xXAny active infection requiring systemic treatmentXx_NEWLINE_xXCurrent active infection requiring systemic antibiotic or antifungal therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXPatients active infection requiring intravenous systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXSystemic infection requiring chronic maintenance or suppressive therapyXx_NEWLINE_xXPatient has an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection, requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXAcute infection requiring systemic treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSubjects must not have a known active infection requiring intravenous antibiotic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy; exception HIV on antiretrovirals with negative viral loadXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXOngoing infection requiring systemic treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapy which is not expected to have resolved by cycle 1 day 1 dosingXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy =< 14 days prior to registrationXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXCurrent active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHave an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy; antimicrobial prophylaxis will be permitted at the discretion of the treating investigatorXx_NEWLINE_xXActive infection requiring treatment.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapy or hospital admissionXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapy or hospital admissionXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring intravenous antibiotic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHave any active disease requiring systemic immunosuppressive treatmentXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic treatmentXx_NEWLINE_xXAny other active malignancy requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days prior to start of study treatmentXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXAcute active infection requiring systemic therapy within 2 weeks prior to enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapy or hospital admissionXx_NEWLINE_xXHas an active serious bacterial infection requiring systemic therapyXx_NEWLINE_xXSubject has an active infection requiring systemic therapy, including active tuberculosisXx_NEWLINE_xXInfection requiring systemic IV antibiotic therapy within 7 days before cycle 1 day 1 of therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXActive (uncontrolled) infection requiring systemic antibiotic therapy with antibacterial, antifungal, or antiviral agents (excluding HIV)Xx_NEWLINE_xXRequiring active treatment for Toxoplasma gondii infectionXx_NEWLINE_xXUncontrolled systemic infection requiring parenteral anti-microbial therapy.Xx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive, systemic infection requiring intravenous (IV) antibiotic, antifungal, or antiviral therapy or other serious infection within 14 days before the first dose of study drug.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXPatient has an active infection requiring systemic therapyXx_NEWLINE_xXAcute active infection requiring treatment should be under controlXx_NEWLINE_xXActive carcinoma requiring systemic chemotherapy or radiation therapyXx_NEWLINE_xXPatients with active infection requiring systemic antimicrobialsXx_NEWLINE_xXActive systemic infectionXx_NEWLINE_xXChronic or current active infection requiring systemic antibiotic, antifungal, or antiviral treatmentXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic antibiotic therapy. Patients requiring systemic antibiotics for infection must have completed therapy before Screening is initiatedXx_NEWLINE_xXRecent infection requiring systemic treatment that was completedXx_NEWLINE_xXAn active infection requiring systemic IV therapy.Xx_NEWLINE_xXSubject has active infection requiring systemic therapy that has not completely resolved within 14 days prior to start of study treatment.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy NOTE: Antibiotic therapy must have been completed a minimum of 3 days prior to start of study treatment;Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive systemic infection requiring parenteral antibiotic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollment.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXPatient has an active systemic infection requiring treatment or within 14 days before first dose of PRLX 93936.Xx_NEWLINE_xXSerious, concomitant disorder, including active systemic infection requiring treatment, in the opinion of the investigator;Xx_NEWLINE_xXActive infection requiring systemic therapy;Xx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring treatment.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXEvidence of active tuberculosis or recent clinically-significant infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXInfection requiring systemic antibiotic therapy within 14 days prior to the start of study treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXREGISTRATION TO TREATMENT (STEP 1): Patient must not have an active infection requiring systemic therapyXx_NEWLINE_xXREGISTRATION TO TREATMENT (STEP 2): Patient must not have an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection ? 7 days prior to registrationXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXPatient has an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXAcute infection requiring systemic treatmentXx_NEWLINE_xXHas an active viral infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive systemic infection requiring treatment, including any human immunodeficiency virus (HIV) infection or toxoplasmosisXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy with the exception of an uncomplicated urinary tract infectionXx_NEWLINE_xXEvidence of ongoing or active infection requiring antibiotic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXActive or chronic infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring treatment or chronic infection requiring suppressive therapyXx_NEWLINE_xXActive infection requiring systemic treatment within one week prior to first dose.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXParticipants with an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapy with antibacterial, antifungal, or antiviral agents (excluding HIV)Xx_NEWLINE_xXRequiring active treatment for Toxoplasma gondiiXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy or history of repeated infectionsXx_NEWLINE_xXSystemic infection requiring chronic maintenance or suppressive therapyXx_NEWLINE_xXPatients with active infection requiring systemic antimicrobialsXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring intravenous systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXAny active infection requiring antibiotic therapy within 2 weeks of study day 1.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXPatients must not have an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring therapy.Xx_NEWLINE_xXActive infection requiring treatment ? 7 days before first dose of study drugXx_NEWLINE_xXHas an active infection or recent history (<30 days before study drug administration) requiring systemic treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXPresence of active infection requiring systemic therapyXx_NEWLINE_xXSubject has active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy at enrollmentXx_NEWLINE_xXHas an active infection requiring systemic treatmentXx_NEWLINE_xXActive systemic infection requiring treatment. Infection controlled by oral therapy will not be exclusionary.Xx_NEWLINE_xXHas an active infection requiring systemic therapy or uncontrolled infection.Xx_NEWLINE_xXActive systemic infection requiring treatment. Infection controlled by oral therapy will not be exclusionary.Xx_NEWLINE_xXNo active systemic infection requiring parenteral antibiotic therapyXx_NEWLINE_xXNo disease requiring systemic immunosuppressive therapyXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXSystemic infection requiring IV antibiotic therapy within 7 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection (any infection requiring treatment).Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXNo active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring IV systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy within 14 daysXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before first dose of study drugXx_NEWLINE_xXSerious infection requiring systemic antibiotic therapy within 14 days prior to study treatment.Xx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic antibiotic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic antibiotic therapy. Patients requiring systemic antibiotics for infection must have completed therapy before ScreeningXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXOngoing or active infection requiring systemic treatmentXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXParticipant has an active infection requiring therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy (? grade 2) for more than 3 days within 1 week of enrollment.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring IV antibiotic therapy within 7 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXActive infection requiring treatment ?7 days before the first dose of study drugXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring treatment within two weeks prior to first dose.Xx_NEWLINE_xXHas any active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXActive infection (any infection requiring treatment).Xx_NEWLINE_xXActive infection requiring systemic antibiotic therapyXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXPresence of an active systemic infection requiring treatment.Xx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before randomization.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXEvidence of active viral, bacterial, or systemic fungal infection requiring systemic treatment within 7 days prior to the first dose of study drug. Patients requiring any systemic antiviral, antifungal, or antibacterial therapy for active infection must have completed treatment no less than 7 days prior to the first dose of study drug.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy;Xx_NEWLINE_xXActive infection (any infection requiring systemic treatment)Xx_NEWLINE_xXActive systemic infectionXx_NEWLINE_xXSubject has evidence of an active infection requiring systemic therapy within 14 days prior to the planned first dose of study drug.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring therapyXx_NEWLINE_xXEvidence of active infection requiring systemic therapyXx_NEWLINE_xXHave an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring IV antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXSubject has evidence of active infection requiring systemic therapy within 14 days prior to the first dose of study drug.Xx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXActive systemic infectionXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXPresence of uncontrolled infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSubject has systemic infection requiring intravenous (IV) antibiotic therapy within 7 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXActive systemic infection requiring systemic antibiotic treatment within 72 hours prior to first dose of study treatmentXx_NEWLINE_xXActive systemic hepatitis infection requiring treatment or other clinically active liver diseaseXx_NEWLINE_xXevidence of active infection requiring systemic therapy.Xx_NEWLINE_xXSerious, uncontrolled infection requiring systemic antibiotic, antifungal or antiviral therapyXx_NEWLINE_xXActive infection requiring systemic antibacterial/antibiotic, antifungal, or antiviral therapy.Xx_NEWLINE_xXAcute active infection requiring treatment.Xx_NEWLINE_xXAcute active infection requiring treatment.Xx_NEWLINE_xXInfection requiring IV antibiotic therapy or other serious infection within 14 days prior to first dose of study drugXx_NEWLINE_xXSystemic infection requiring IV antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXActive infection requiring therapyXx_NEWLINE_xXPatient has an active systemic infection requiring treatment.Xx_NEWLINE_xXActive, serious infection requiring systemic therapyXx_NEWLINE_xXPatients with active infection requiring systemic treatmentXx_NEWLINE_xXActive infection requiring antibiotic treatmentXx_NEWLINE_xXActive infection requiring antibiotic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous (IV) antibiotic therapy within 14 days preceding the first dose of study drug, or other severe infectionXx_NEWLINE_xXEvidence of active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapyXx_NEWLINE_xXHas active infection requiring systemic therapyXx_NEWLINE_xXPatients must not have an active infection requiring systemic therapy nor a viral infection requiring intermittent treatment with an antiherpetic drug, other than intermittent topical useXx_NEWLINE_xXSystemic infection requiring IV antibiotic therapy or other serious infection within 14 days before the first dose of study drug.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive systemic infectionXx_NEWLINE_xXRecent infection requiring intravenous systemic treatment that was completed =< 14 days before the first dose of study drug or any uncontrolled active systemic infectionXx_NEWLINE_xXRecent infection requiring systemic treatment that was completed =< 7 days before the first dose of study drugXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring IV anti-infective therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXA serious, concomitant disorder, including active systemic infection requiring treatmentXx_NEWLINE_xXActive infection requiring within 2 weeks prior to first dose of study drugXx_NEWLINE_xXKnown active infection requiring antibiotic treatmentXx_NEWLINE_xXInfection requiring systemic antibiotic therapy within 14 days prior to start of study treatmentXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic IV antibiotic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXCurrent active infection requiring systemic treatment.Xx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXActive infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic treatmentXx_NEWLINE_xXInfection requiring systemic antibiotic therapy or other serious infection within 14 days before study enrollmentXx_NEWLINE_xXhave an active infection requiring antibiotic therapy, or concomitant malignanciesXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXSystemic infection requiring intravenous antibiotic therapy or other serious infection within 14 days before the first dose of study drug.Xx_NEWLINE_xXHas an active infection requiring systemic therapy.Xx_NEWLINE_xXActive infection (any infection requiring treatment).Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring intravenous systemic therapy.Xx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xXHas an active infection requiring systemic therapyXx_NEWLINE_xX