Creatinine level greater than 1.5 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) orXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXWithin 14 days prior to registration: Creatinine =< 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal within 4 weeks before randomizationXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) documented within 28 days prior to step 1 registrationXx_NEWLINE_xXCreatinine < 1.5 times institutional upper limit of normal, within 21 days prior to study entryXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normal (ULN), measured within 28 days prior to administration of study treatmentXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine ? 2 × upper limit of normal (ULN) ORXx_NEWLINE_xXAdequate renal function as evidenced by a serum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXPatients with a creatinine =< 2 x upper limit of normal for ageXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normal (ULN) ORXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 X institutional upper limit of normal\r\n* Creatinine (Cr) < 2, blood urea nitrogen (BUN) < 100 mg/dLXx_NEWLINE_xXSerum creatinine ? 1.5 × upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXCreatinine > 1.5 × upper limit of normal (ULN).Xx_NEWLINE_xXCreatinine within less than the institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 X the institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal rangeXx_NEWLINE_xXTREATMENT: Creatinine =< 2 x upper limit of normal for ageXx_NEWLINE_xXSerum creatinine less than 3 times upper limit of normalXx_NEWLINE_xXPatients with a creatinine =< 2 x normal for ageXx_NEWLINE_xXSerum creatinine ?1.5 × upper limit of normal (ULN);Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXObtained =< 2 weeks prior to registration: Serum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXObtained within 28 days prior to registration: Creatinine < 1.5 x upper limit of normal (ULN), ORXx_NEWLINE_xXPatients with a creatinine normal for ageXx_NEWLINE_xXSerum creatinine =< 2 x the upper limit of normal (ULN)Xx_NEWLINE_xXObtained within 14 days prior to registration: Creatinine =< 1.5 x the institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine: =< 1.5 x upper limit of normal (ULN) within 8 weeks of pre-registrationXx_NEWLINE_xXINCLUSION - INFUSION: Patients with a creatinine ? 2 x upper limit of normal for ageXx_NEWLINE_xXSerum creatinine < 2 x upper normal limitXx_NEWLINE_xXSerum creatinine < 1.5x institution upper limit of normalXx_NEWLINE_xXSerum Creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine ? 1.5 X age-adjusted upper limits of normal (ULN)Xx_NEWLINE_xXSerum Creatinine ?1.5 × institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine ? 1.5 x upper limit of normal (ULN) or Creatinine clearance ? 50% of lower limit of normal (LLN)Xx_NEWLINE_xXserum creatinine < upper limit of normal (ULN);Xx_NEWLINE_xXCreatinine > 1.5 × upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine value of < 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine ? 2X upper limit of normalXx_NEWLINE_xXCreatinine ?1.5 x the upper limit of normalXx_NEWLINE_xXSerum creatinine ? 2 x upper limit of normalXx_NEWLINE_xXSerum creatinine ? 1.5 x upper limit or normalXx_NEWLINE_xXELIGIBILITY CRITERIA AT TIME OF TREATMENT: Patients with a creatinine ? 2 x upper limit of normal for ageXx_NEWLINE_xXPatients with a creatinine ? 2x upper limit of normal for ageXx_NEWLINE_xXCreatinine < 2.0 times upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of normal; ORXx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXINCLUSION - TREATMENT: Serum creatinine ? 2x upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) for reference labXx_NEWLINE_xXCreatinine ? 1.5 x upper limit of normalXx_NEWLINE_xXCreatinine < 1.5 x upper limit of normal (or ULN)Xx_NEWLINE_xXPatients with impaired renal function as evidenced by creatinine-clearance < 50% for age, weight, height or serum creatinine > 2 x upper normal limit or dialysis-dependentXx_NEWLINE_xXWithin 14 days of randomization: Creatinine =< 1.5 x the institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine within 1.5 x upper limit of normal institutional limitsXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 x the institutional upper limit of normal.Xx_NEWLINE_xXSerum creatinine < 1.5 times institutional upper limit of normalXx_NEWLINE_xXSerum creatinine ? 2 x the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN), within 2 weeks of registrationXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXSerum creatinine =< upper limit of institutional normalXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine level less than or equal to 1.5 x institutional upper limit normal (ULN) (CTCAE v4.03 grade 1)Xx_NEWLINE_xXSerum creatinine > 2 times the upper limit of normalXx_NEWLINE_xXWithin 14 days prior to registration: Creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) or >= 60 mL/minute for subjects with creatinine levels > 1.5 x the institutional ULNXx_NEWLINE_xXSerum creatinine < 2 × upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 x upper limits of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 X institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN), within 2 weeks of registration (except where specified otherwise)Xx_NEWLINE_xXWithin 4 weeks prior to the registration: creatinine =< 2 X the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXAdequate renal function: serum creatinine less than 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 X upper limit of normal (ULN).Xx_NEWLINE_xXSerum creatinine < 2.0 x upper limit of normalXx_NEWLINE_xXSerum creatinine ? 1.5 x institution’s ULN (upper limit of normal)Xx_NEWLINE_xXCreatinine < 1.5 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine within normal rangeXx_NEWLINE_xXSerum creatinine =< 1.5 x ULN (upper limit of normal)Xx_NEWLINE_xXCreatinine levels < 1.5 x upper limit of normal (ULN).Xx_NEWLINE_xXCreatinine =< 1.5 upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x institution upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x institution upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine of < 3.0 x ULN (upper limit of normal)Xx_NEWLINE_xXSerum creatinine =< 2.0 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine within 1.5 x upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXCompleted within 10 days of SBRT treatment initiation: Serum creatinine =< 1.5 X upper limit of normal (ULN) ORXx_NEWLINE_xXSerum creatinine =< 1.5 X upper limit of normal (ULN) ORXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 X institutional upper limit of normal (ULN)Xx_NEWLINE_xXAdequate renal function, as indicated by creatinine =< 1.5 x the upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 x age-adjusted upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine of =< 1.5 x the upper limit of normalXx_NEWLINE_xXObtained =< 14 days prior to registration: Serum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal ORXx_NEWLINE_xXPHASE I: Creatinine < 1.5 x the institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine ? 2 times upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine less than or equal to 2 x upper limit of normal (ULN)Xx_NEWLINE_xXRenal impairment as evidenced by serum creatinine >1.5 × upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine ?1.5 × upper limit of normal (ULN) for institutionXx_NEWLINE_xXCreatinine ? 1.5 x upper limit of normal (ULN) or Creatinine clearance ? 50%Xx_NEWLINE_xXSerum creatinine concentration < 3 x the upper limit of normal (ULN) based on the age of the patientXx_NEWLINE_xXSerum creatinine of =< 1.5 times upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 X institutional upper limit of normal (ULN) (measured within 28 days prior to administration of study treatment)Xx_NEWLINE_xXSerum creatinine value of =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine ? 1.5 x upper limit of normal (ULN) orXx_NEWLINE_xXCreatinine =< 1.5 X upper limits of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXAT THE TIME OF INFUSION: Serum creatinine ? 2x upper limit of normal for ageXx_NEWLINE_xXCreatinine less than or equal to 1.5 x institutional upper limit of normal (ULN), CTCAE version 4 grade 1Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine less than or equal to 1.5 x institutional upper limit of normal for ageXx_NEWLINE_xXCreatinine levels < 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of institutional normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXEXCLUSION CRITERIA FOR ENROLLMENT: Creatinine >= 2.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 2 times the upper limits of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.2 x the upper limit of normal (ULN) prior to biopsyXx_NEWLINE_xXTREATMENT: Patients with a creatinine ? 2 x upper limit of normal for ageXx_NEWLINE_xXCreatinine (Cr) =< 1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 times the upper limit of normalXx_NEWLINE_xXSerum creatinine > 1.5 times the upper limit of normalXx_NEWLINE_xXCreatinine less than or equal to 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x the institutional upper limit of normalXx_NEWLINE_xXplasma creatinine ? 1.5 x upper limit of normal (ULN) for the institutionXx_NEWLINE_xXSerum creatinine =< 1.5 times the upper limit of normal (ULN) (normal: =< 1.17 mL/min/1.73 m^2)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine of =< 1.5 × upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXC. Renal: Serum creatinine (sCr) ? 1.5 x upper limit of normal.Xx_NEWLINE_xXCreatinine < 1.5 X upper limit of normal (ULN) orXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine concentration, 1.5 times greater than the upper limit of laboratory normal ranges (ULN), except if related to ALL/LBL,Xx_NEWLINE_xXCreatinine =< 1.5 X institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.2 times the upper limit of normalXx_NEWLINE_xXSerum creatinine < 3 x upper limit of normal for ageXx_NEWLINE_xXSerum creatinine less than 3 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 times upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normal (IULN)Xx_NEWLINE_xXSerum creatinine < 2.0 x the upper limits of institutional normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x upper limit of normalXx_NEWLINE_xXCreatinine less than 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of normalXx_NEWLINE_xXPatients must have normal organ function as defined below:\r\n* Serum creatinine < 2.0 x institutional upper limit of normal (ULN)\r\n* International normalized ratio (INR) < 1.5 x institutional ULNXx_NEWLINE_xXCreatinine less or equal to 3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x upper limit of normal for ageXx_NEWLINE_xXCreatinine =< 3 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< institutional upper limit of normalXx_NEWLINE_xXCreatinine =< institutional upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine clearance >= 50 mg/dl OR serum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 times upper limit of institutional for age orXx_NEWLINE_xXSerum creatinine 1.5 times or less than upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 x upper limit of normalXx_NEWLINE_xXSerum creatinine less than 1.5 times the upper limits of normal within 7 days prior to starting treatmentXx_NEWLINE_xXAdequate renal function defined as serum creatinine equal to or less than 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 x upper limit of normalXx_NEWLINE_xXBilirubin and creatinine less than 2 × upper limit of normal (ULN) for the institutionXx_NEWLINE_xXSerum creatinine ? 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit normal (ULN) and calculated creatinine clearance of >= 60mL/minXx_NEWLINE_xXCreatinine: < 1.5 x institutional upper limit of normalXx_NEWLINE_xXRenal function: creatinine ? 1.5 x institutional upper limit of normal (ULN);Xx_NEWLINE_xXWithin 14 days prior to registration: Serum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine < 2.0 x the upper limits of institutional normal (ULN)Xx_NEWLINE_xXSerum creatinine ? 1.5x upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) OR >= 60 mL/minXx_NEWLINE_xXSerum creatinine ? 1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 4 X institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXCreatinine greater than or equal to 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) orXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of institutional normalXx_NEWLINE_xXCreatinine =< institutional upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 mg/dL x the institutional upper limit of normalXx_NEWLINE_xXRenal disease: serum creatinine > 2 times upper limit of normalXx_NEWLINE_xXSecondary Registration: serum creatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 times the upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 x the institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 2 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXCreatinine =< 2.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal and/or creatinine clearance > 50% lower limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 X institutional upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< the institutional upper limit of normalXx_NEWLINE_xXCreatinine < 1.5 x institutional upper limit of normal ORXx_NEWLINE_xXWith impaired renal function as evidenced by creatinine-clearance < 50% for age, weight, height or serum creatinine > 2 x upper limit of normal or dialysis-dependentXx_NEWLINE_xXSerum creatinine =< 1.5 times the institutional upper limit of normalXx_NEWLINE_xXSerum creatinine less than 3 times upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normal (ULN), measured within 28 days prior to administration of study treatmentXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXCreatinine =< 2 times upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5x upper limit of normalXx_NEWLINE_xXRegimens I and II: Creatinine =< 1.5 x institutional upper limit normal (ULN), CTCAE grade 1\r\n* Regimen III: Creatinine no greater than the institutional upper limits of normalXx_NEWLINE_xXSerum creatinine =< 2 x upper limit of normalXx_NEWLINE_xXSerum creatinine less than 3 times upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine > 1.5 x upper limit of normalXx_NEWLINE_xXCreatinine < 1.5 x institutional upper limit of normal (IULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine >= 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine < 2 x the upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXA serum creatinine of ?1.5 x Upper Limit of Normal ULN ORXx_NEWLINE_xXSerum creatinine < 1.5 X upper limit of normal (ULN) (institutional)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine less than or equal to 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limits of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXWithin 56 days prior to randomization: Serum creatinine =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXSerum creatinine < 2.5 x the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) within 14 days prior to study registrationXx_NEWLINE_xXSerum creatinine =< 2.0 mg/dL for patients over 18 years or =< 2.5 x institutional upper limit of normal (ULN) for ageXx_NEWLINE_xXSerum creatinine ? 1.5 X upper limit of normalXx_NEWLINE_xXSerum creatinine should be within normal limits as specified by institutional guidelines; for patients with serum creatinine > upper limit of normal, a 24-hour creatinine clearance will be performed and should be equal to or more than the lower limit of normalXx_NEWLINE_xXCreatinine =< 2 times the upper limits of normal (ULN)Xx_NEWLINE_xXCreatinine =< 3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional/laboratory upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine ?1.5 X upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x the institutional normal upper limitXx_NEWLINE_xXCreatinine =< 2.0 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXAdequate renal function defined as serum creatinine ?3 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 X institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 2 x institutional upper limit of normal if patient has chronic renal insufficiency and creatinine has been stable x > 4 monthsXx_NEWLINE_xXSerum creatinine 1.5 times or less than upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 X ULN (the upper limit of normal)Xx_NEWLINE_xXSerum creatinine within 3 times the upper limits of normalXx_NEWLINE_xXCreatinine within 1.5 times of the institution's upper limit of normal (ULN)Xx_NEWLINE_xXPrior to cyclophosphamide and T cell infusions: creatinine >= 3.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 2 x institution upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 X upper limit of normal (ULN) (within 14 days of treatment initiation) ORXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of normal; ORXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN), should be performed within 28 days of treatment initiation, unless otherwise indicated ORXx_NEWLINE_xXSerum creatinine > 3 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine (Cr) < 1.5 upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x institutional upper limit of normalXx_NEWLINE_xXCreatinine > 1.5 x the upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN); institutional norms are acceptableXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 2.0 times upper normal limitXx_NEWLINE_xXCreatinine =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXAT THE TIME OF INFUSION: Creatinine ? 2 x upper limit of normal for ageXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 times the upper limit of normal (ULN)Xx_NEWLINE_xXRenal: Serum creatinine (sCr) ? 2.0 x upper limit of normal.Xx_NEWLINE_xXCreatinine < 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine >= 3.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine within 1.5 x the upper limit of normal (ULN) institutional limitsXx_NEWLINE_xXCOHORT A: Creatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x upper limits of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 times the upper limits of normal (ULN)Xx_NEWLINE_xXSerum creatinine </=2x upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x the institutional upper limit of normal obtained within 14 days prior to start of therapyXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x the upper limit of normal range, or, if serum creatinine > 1.5 x the upper limit or normal range, then the creatinine clearance must be >= 60 mL/minXx_NEWLINE_xXSerum creatinine > 2 x upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (institutional ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73m^2 for patients with creatinine >= 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 times the institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal ORXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine > 2.0 times upper normal limitXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normalXx_NEWLINE_xXCreatinine > 1.5 times the institutional upper limit of normalXx_NEWLINE_xXSerum Creatinine =< 1.5 X the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine of =< 1.5 X the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN), CTCAE grade 1Xx_NEWLINE_xXCreatinine =< 3.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.2 x normal prior to biopsyXx_NEWLINE_xXWithin 14 days prior to registration: Creatinine =< 1.5 x upper limit of normal rangeXx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine: ~ 2 x upper limit or normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 times upper limit of normalXx_NEWLINE_xXCreatinine =< 2 X institutional upper limit of normalXx_NEWLINE_xXSerum creatinine within 1.5 x upper limit of normal (CTCAE 4.0 grade 1 abnormality is acceptable)Xx_NEWLINE_xXCreatinine =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x institution upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2 X upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN) for children and =< 2.0 x ULN for adultsXx_NEWLINE_xXCreatinine < 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x institutional upper limit of normal (ULN), obtained within 14 days prior to first treatmentXx_NEWLINE_xXCreatinine =< 3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 times upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal for the laboratoryXx_NEWLINE_xXCreatinine < 1.5 institutional upper limit of normal ORXx_NEWLINE_xXCreatinine =< 2 x upper limit of normal for ageXx_NEWLINE_xXNormal creatinine for ageXx_NEWLINE_xXSerum creatinine < 1.5 times upper limit of laboratory normalXx_NEWLINE_xXSerum creatinine concentration < 3 X the institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x normalXx_NEWLINE_xXCreatinine < 2 times upper limit of normalXx_NEWLINE_xXSerum creatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine less than or equal to 1.5 x upper limit of normal, CTCAE v 4.0 grade 1Xx_NEWLINE_xXSerum creatinine of at least 1.5 times the upper limit of normalXx_NEWLINE_xXPatient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN); either lab result or calculated clearanceXx_NEWLINE_xXCreatinine =< 1.6 x the upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine less than or equal to 1.5 x institutional upper limit normal (ULN), CTCAE v4.0 grade 1Xx_NEWLINE_xXCreatinine: =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 times the upper limit of normalXx_NEWLINE_xXSerum creatinine > 2 x upper limit of normal, unless there is known CKD (creatinine must be at baseline for subjects with CKD)Xx_NEWLINE_xXCreatinine < 2.5 times the upper limit of normalXx_NEWLINE_xXSerum creatinine >= 2 x upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 times the institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 the institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 X institutional upper limit of normalXx_NEWLINE_xXHas adequate renal function as evidenced by serum creatinine ?2.5 × the upper limit of normal (ULN) for the reference lab;Xx_NEWLINE_xXSerum creatinine =< 1.5 x the upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine less than or equal to 1.5 x institutional upper limit normal (ULN)Xx_NEWLINE_xXSerum creatinine less than 1.5 times the upper limits of normalXx_NEWLINE_xXCreatinine =< 2.0 x upper limit of institutional normal for ageXx_NEWLINE_xXSerum creatinine >= 2 x upper limit of normalXx_NEWLINE_xXSerum creatinine (Cr) ? 1.5 x upper limit of normal (ULN).Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal orXx_NEWLINE_xXserum creatinine of ? 1.5x upper limit of normal (ULN) for the reference lab.Xx_NEWLINE_xXPatient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.Xx_NEWLINE_xXSerum creatinine =< 1.5 x institution’s ULN (upper limit of normal), orXx_NEWLINE_xXCreatinine < 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 2 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 X institutional upper limit of normalXx_NEWLINE_xXInadequate renal function as indicated by serum creatinine >= 1.5 times the upper limit of normalXx_NEWLINE_xXSerum creatinine < 1.5 × the upper limit of normal (ULN).Xx_NEWLINE_xXCreatinine =< 3 x institutional upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limitXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine (Cr) =< 1.5 x upper limit normalXx_NEWLINE_xXCreatinine < 1.5 X Upper Limit of the Normal (ULN)Xx_NEWLINE_xXSerum creatinine < 2 x institutional upper limit of normal ORXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine ? 3 times the upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN), within 14 days prior to initiation of study drugXx_NEWLINE_xXCreatinine needs to be less than or equal to 1.3 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 2.0 mg/dL (< 2 x upper limit of normal [ULN])Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) for ageXx_NEWLINE_xXCreatinine =< 3.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normal (ULN), CTCAE grade 1Xx_NEWLINE_xXSerum creatinine of =< 1.5 X the upper limit of normalXx_NEWLINE_xXAdequate renal function, as indicated by creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine > 1.5 X upper limit of normal.Xx_NEWLINE_xXCreatinine =< 3 x upper limit of normal (ULN)Xx_NEWLINE_xXRenal: serum creatinine less than 2x upper limit of normal for age (as per local laboratory)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXSerum creatinine > 1.5 x upper limit of normal (ULN) or creatinine clearance < 60 mL/minuteXx_NEWLINE_xXCreatinine =< 2.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXGrade 2 renal dysfunction: creatinine > 2-3 times the upper limit of normalXx_NEWLINE_xXPerformed within 10 days of treatment initiation: Creatinine =< 1.5 x upper limit normal (ULN) ORXx_NEWLINE_xXSerum creatinine =< upper limit of normal (ULN)Xx_NEWLINE_xXSubjects who have a serum creatinine > 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine < 1.5 times the upper limit of normal, or:Xx_NEWLINE_xXSerum creatinine =< 2.5 x upper limit of normal (ULN) (within 7 days)Xx_NEWLINE_xXCreatinine < 1.5 x upper limit of normal (ULN) ORXx_NEWLINE_xXBaseline creatinine (Cr) no greater than 1.5 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 times the upper limit of normalXx_NEWLINE_xXCreatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 x the upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 times the upper limit of normalXx_NEWLINE_xXSerum creatinine < institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 x upper limit normalXx_NEWLINE_xXCreatinine < 3.0 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine ? 1.5 x upper limit of normal (ULN) of institution's range or Creatinine clearance ? 50%Xx_NEWLINE_xXCreatinine =< institutional upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine < 1.5 x upper limits of normal, orXx_NEWLINE_xXSerum creatinine =< 2.0 x upper limits of normal, orXx_NEWLINE_xXNormal renal function as determined by a serum creatinine < upper limit of normalXx_NEWLINE_xXSerum creatinine within 1.5 x upper limit of institutional normalXx_NEWLINE_xXCreatinine =< 2.5 x institutional upper limit of normal (ULN) obtained =< 45 days prior to randomizationXx_NEWLINE_xXCreatinine =< 1.5 x institutional upper limit of normalXx_NEWLINE_xXSerum creatinine > 2.5 x ULN (upper limit of normal)Xx_NEWLINE_xXCreatinine =< 1.5 x the institutional upper limit of normal (ULN), obtained within 14 days prior to treatment startXx_NEWLINE_xXCreatinine =< institutional upper limit of normal ORXx_NEWLINE_xXWithin 30 days of eligibility confirmation: Creatinine not above the upper limit of normal institutional limitsXx_NEWLINE_xXMeasured within 28 days prior to administration of study treatment: Serum creatinine =< 1.5 x institutional upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< twice upper limit institutional normalXx_NEWLINE_xXPatients with a creatinine =< 2 x normal for ageXx_NEWLINE_xXSerum creatinine ? 1.5 x upper limit of normal (ULN) for ageXx_NEWLINE_xXCreatinine =< 2.0 times the upper limit of normalXx_NEWLINE_xXSerum creatinine less than or equal to 1.5 x institutional upper limit normal (ULN)Xx_NEWLINE_xXSUB-STUDY I: Serum creatinine > 2 time the upper limit of normalXx_NEWLINE_xXSUB-STUDY II: Serum creatinine > 2 time the upper limit of normalXx_NEWLINE_xXSUB-STUDY III: Serum creatinine > 3 times the upper limit of normalXx_NEWLINE_xXSerum creatinine > 2 times the upper limit of normalXx_NEWLINE_xXSerum creatinine > 2 times the upper limit of normalXx_NEWLINE_xXCreatinine > 2 x upper limit of normalXx_NEWLINE_xXCreatinine =< 1.5 x the institutional upper limit of normalXx_NEWLINE_xXSerum creatinine > 1.5 times upper limit of normalXx_NEWLINE_xXSerum creatinine > 3 times the upper limit of normalXx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 2 x upper limit of normal (ULN)Xx_NEWLINE_xXSubjects must have adequate renal function as defined by serum creatinine < 1.5 x upper limit of normalXx_NEWLINE_xXSerum creatinine =< institutional upper limit of normal (IULN)Xx_NEWLINE_xXCreatinine >= 1.5 times upper limit of normalXx_NEWLINE_xXCreatinine >= 1.5 times upper limit of normalXx_NEWLINE_xXSerum creatinine > 2 times the upper limit of normalXx_NEWLINE_xXSignificant history or current renal insufficiency (serum creatinine > 1.5 institutional upper limit of normal)Xx_NEWLINE_xXSerum creatinine > 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine =< 1.5 times the institution upper limit of normal (ULN)Xx_NEWLINE_xXCreatinine > 1.5 times the institution upper limit of normal (ULN)Xx_NEWLINE_xXSerum creatinine =< 1.5 x upper limit of normal (ULN)Xx_NEWLINE_xXHave a serum creatinine above 1.5 upper limit of normal (ULN) (collected within the past 4 weeks); ULN is per institutional definitionXx_NEWLINE_xXSerum creatinine ? 1.5 x upper limit of normal (ULN).Xx_NEWLINE_xX