Known history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXPatients must not have clinical signs or symptoms of active tuberculosis infectionXx_NEWLINE_xXPatient must not have active tuberculosisXx_NEWLINE_xXPatients must not have known history of tuberculosisXx_NEWLINE_xXPatient must not have active tuberculosisXx_NEWLINE_xX11. Known history of tuberculosis;Xx_NEWLINE_xXHas a known history of active tuberculosis (Bacillus tuberculosis).Xx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown active TB (Bacillus tuberculosis); patients with a distant history of tuberculosis that was appropriately treated and have no evidence of active infection are eligible to participate; patients with a history of latent tuberculosis that was appropriately treated are also eligible to participateXx_NEWLINE_xXKnown history of previous diagnosis of tuberculosis.Xx_NEWLINE_xXActive hepatitis B or C, or tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosis.Xx_NEWLINE_xXHas a known history of active tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosisXx_NEWLINE_xXPatients with clinically active tuberculosis.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXKnown history of active tuberculosis.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXSubjects with a history of tuberculosis or a history of a chest X-ray suspicious for tuberculosis, unless confirmed to be purified protein derivative (PPD) negative or latent tuberculosis that has been previously treated.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHistory of primary immunodeficiency or history of active tuberculosis; Note: latent tuberculosis will not be a basis for exclusionXx_NEWLINE_xXKnown active tuberculosis.Xx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown active tuberculosis or fungal infectionXx_NEWLINE_xXSignificant acute or chronic infections including tuberculosis (history of exposure or history of positive tuberculosis test; plus, presence of clinical symptoms, physical or radiographic findings)Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHas a known history of tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosisXx_NEWLINE_xXGENERAL: Active tuberculosis.Xx_NEWLINE_xXActive tuberculosis infectionXx_NEWLINE_xXHas a known history of active tuberculosis (Bacillus tuberculosis).Xx_NEWLINE_xXHepatitis B or C, tuberculosis, or HIV.Xx_NEWLINE_xXHistory of active tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosis.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXactive tuberculosis (history of exposure or history of positive TB test with presence of clinical symptoms, physical or radiographic finding);Xx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXHas known history of active tuberculosisXx_NEWLINE_xXKnown history of previous tuberculosisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosis based on history, symptoms, physical exam, imagingXx_NEWLINE_xXHistory of tuberculosis treatment within 2 years of study entryXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive or latent tuberculosis or hepatitisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosis (Bacillus tuberculosis infection)Xx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosis.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXParticipants with suspected active or latent tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXHas a known history of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXPatients with active tuberculosis are not eligibleXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXHistory of primary immunodeficiency or tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown active or latent tuberculosisXx_NEWLINE_xXNegative for tuberculosis antigen (e.g. T-Spot test)Xx_NEWLINE_xXPHASE I STUDY ELIGIBILITY CRITERIA:\r\nKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXPHASE II COLORECTAL CANCER COHORT 6 (MEDI+C ONLY):\r\nKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXSubjects with a known history of tuberculosis or on anti-tuberculosis medicationXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXknown clinical diagnosis of tuberculosis;Xx_NEWLINE_xXHistory of tuberculosis treated within the last five years or recent exposure to tuberculosisXx_NEWLINE_xXActive tuberculosis or untreated, latent tuberculosis\r\n* If a patient has signs, symptoms, or a history suggestive of active tuberculosis, evaluation by an infectious disease physician will be required and active tuberculosis ruled-out prior to enrollmentXx_NEWLINE_xXHistory of tuberculosis or history of tuberculosis skin test purified protein derivative (PPD) positivityXx_NEWLINE_xXWillingness to complete tuberculosis evaluation and start prophylactic antituberculosis therapy as soon as is medically feasible if patients have a reactive tuberculin skin test and/or positive QuantiFERON-tuberculosis (TB) Gold test and have not completed an adequate course of prevented anti-tuberculosis therapy, following American Thoracic Society/Centers for Disease Control recommended guidelinesXx_NEWLINE_xXTuberculosis, history of tuberculosis or a known positive Quantiferon test for tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous diagnosis of tuberculosis.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosis (history of exposure or history of positive TB test with presence of clinical symptoms, physical or radiographic finding);Xx_NEWLINE_xXPatients with clinically active tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosisXx_NEWLINE_xXActive tuberculosis.Xx_NEWLINE_xXActive tuberculosis (clinical evaluation that includes clinical history, physical examination and radiographic findings, and tuberculosis testing in line with local practice) infection.Xx_NEWLINE_xXHas a known history of active tuberculosis (TB) (Mycobacterium tuberculosis)Xx_NEWLINE_xXActive tuberculosis OR known history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXPatients with a history of primary immunodeficiency disease or tuberculosis are not eligibleXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXParticipants with known active tuberculosis not on active antitubercular agentsXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHistory of pulmonary fibrosis/inflammation, including active tuberculosisXx_NEWLINE_xXHistory of active or latent tuberculosisXx_NEWLINE_xXActive hepatitis B or C virus infection or active tuberculosisXx_NEWLINE_xXPatients must not have a known history of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXSubject who has history of primary immunodeficiency or tuberculosis.Xx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown active tuberculosis, or hepatitis B or CXx_NEWLINE_xXSubject is know to have active tuberculosis, leishmaniasis, or listeriosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosis or bacillus Calmette-Guerin (BCG) infectionXx_NEWLINE_xXKnown active tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of tuberculosisXx_NEWLINE_xXHistory of known latent or active tuberculosis, signs of active or latent tuberculosis on chest X-ray, skin test showing an induration of > 10 mm or more or according to local recommendationsXx_NEWLINE_xXHas known history of active tuberculosis.Xx_NEWLINE_xXKnown active tuberculosis.Xx_NEWLINE_xXKnown history of active tuberculosis.Xx_NEWLINE_xXKnown history of previous tuberculosis;Xx_NEWLINE_xXKnown history of previous tuberculosisXx_NEWLINE_xXPatients with a history of active tuberculosis within the preceding two yearsXx_NEWLINE_xXPrior vaccination with BCG for tuberculosis diseaseXx_NEWLINE_xXHistory of tuberculosis treatment within the preceding two yearsXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHistory of active tuberculosis.Xx_NEWLINE_xXKnown history of tuberculosisXx_NEWLINE_xXPatients with any known active infection or known history of tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosis (TB; Mycobacterium tuberculosis) or human immunodeficiency virus (HIV) infectionXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of active tuberculosis (this does not include a history of being purified protein derivative [PPD] positive)Xx_NEWLINE_xXPatients with active tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXHas known history of active tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXKnown history of active tuberculosisXx_NEWLINE_xXHistory of tuberculosis treatment within the preceding 2 yearsXx_NEWLINE_xXHistory of primary immunodeficiency or tuberculosisXx_NEWLINE_xXHistory of tuberculosis within the preceding two yearsXx_NEWLINE_xXHistory of tuberculosisXx_NEWLINE_xXPatients with active tuberculosisXx_NEWLINE_xXHistory of tuberculosis (latent or active) or positive Interferon-gamma release assay (IGRA).Xx_NEWLINE_xXThe subject is known to be positive for human immunodeficiency virus (HIV), hepatitis B or C, or active tuberculosis, or has a known history of tuberculosisXx_NEWLINE_xXActive hepatitis B or C and/or tuberculosisXx_NEWLINE_xXSubjects with active tuberculosis are ineligible. In settings where there is clinical or radiographic evidence of tuberculosis, active disease must be ruled outXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHave a history of tuberculosis and/or received BCG percutaneous vaccinationXx_NEWLINE_xXSuspected or latent tuberculosisXx_NEWLINE_xXKnown active or latent tuberculosis infectionXx_NEWLINE_xXSubjects with known history of tuberculosisXx_NEWLINE_xXKnown history or previous clinical diagnosis of tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHistory of tuberculosisXx_NEWLINE_xXKnown history of previous clinical diagnosis of tuberculosisXx_NEWLINE_xXIncompletely treated active tuberculosis infectionXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXPatients with tuberculosisXx_NEWLINE_xXHistory of tuberculosis treated within the last five years or recent exposure to tuberculosisXx_NEWLINE_xXCurrent active tuberculosis or systemic fungal infectionXx_NEWLINE_xXActive tuberculosis, active hepatitis, or positive HIV statusXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXHas a known history of active tuberculosis (Bacillus tuberculosis)Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xXActive infection including tuberculosis, HIV, hepatitis B anc CXx_NEWLINE_xXPatients in Canada may not have a history or evidence of latent or active tuberculosis infection.Xx_NEWLINE_xXActive tuberculosisXx_NEWLINE_xX