The patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks, and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXSubject must be able to give written Institutional Review Board (IRB) approved informed consent and be able to follow protocol requirementsXx_NEWLINE_xXUnderstand and sign an Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved informed consent form (ICF) prior to any study-specific evaluationXx_NEWLINE_xXINCLUSION CRITERIA FOR SECOND-LINE THERAPY: Subject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXSubjects must be competent to comprehend, provide written informed consent, and date an independent ethics committee/institutional review board/research ethics board (IEC/IRB/REB) approved informed consent formXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document and follow study procedures including willingness to undergo study biopsiesXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXSigned written Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXSubject must be fully informed about their illness and the investigational nature of the study protocol (including foreseeable risks and possible side effects) and must sign and date an IRB [Institutional Review Board]-approved Informed consent Form [ICF] (including Health Insurance Portability and Accountability Act authorization, if applicable) before performance of any study specific procedures or tests.Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXPatients must be able to understand and agree to sign an institutional review board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and has provided written informed consent. A legally authorized representative may consent on behalf of a subject who is otherwise unable to provide informed consent, if acceptable to and approved by the site and/or site's Institutional Review Board (IRB)/Independent Ethics Committee (IEC).Xx_NEWLINE_xXSubjects must be willing to sign and provide informed consent and be capable of giving informed consent in accordance with the Institutional Review Board/Ethics Committee policyXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign Institutional Review Board (IRB)-approved informed consentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document that is approved by the local institutional review boardXx_NEWLINE_xXPatient understands the study regimen, its requirements, risks and discomforts and is able and willing to sign the informed consent form; voluntary signed and dated Institutional Review Board (IRB)/Independent Ethics Committee (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines must be obtained before the performance of any protocol related procedures that are not part of normal patient care; subjects must be competent to report adverse events (AEs), understand the drug dosing schedule and use of medications to control AEsXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAble to and provides Institutional Review Board (IRB) approved study specific written informed consentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXEligible and consent to the Institutional Review Board (IRB) 13-0002 registry trial protocolXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatients must sign Institutional Review Board (IRB) approved study specific informed consentXx_NEWLINE_xXPatients must have signed and dated an Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved written informed consent form (ICF) in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal patient careXx_NEWLINE_xXIs willing and able to provide written informed consent for the trial and has signed the appropriate written informed consent form, approved by the investigator’s Institutional Review Board (IRB)/Independent Ethics Committee (IEC), prior to the performance of any trial activities.Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and provide signed informed consent that fulfills institutional review board (IRB)’s guidelinesXx_NEWLINE_xXIs willing to voluntarily sign and date an informed consent form that is approved by an institutional review board before the conduct of any study procedureXx_NEWLINE_xXAll subjects must have the ability to understand and the willingness to sign a written informed consent; signed informed consent form approved by the Institutional Review Board (IRB) is required; the patient, family member, and transplant staff physician (physician, nurse, and social worker) meet at least once prior to starting the transplant procedure; during this meeting, all pertinent information with respect to risks and benefits to the donor and recipient will be presented; alternative treatment modalities will be discussedXx_NEWLINE_xXSubject must voluntarily sign and date an informed consent, approved by an Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an institutional review board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willingness to provide informed consent, and the willingness to comply with the requirements of the protocol\r\n* Subjects must have signed and dated an Institutional Review Board (IRB)/Independent Ethics Committees (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines and before the performance of any protocol related procedures that are not part of standard of careXx_NEWLINE_xXParticipants must be able to give self-consent and then sign and date an Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved written informed consent in accordance with local regulatory and institutional guidelines; this consent must be obtained before the performance of any protocol-related procedures that are not considered part of normal participant careXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXCompetent to comprehend, sign, and date an independent ethics committee/institutional review board/research ethics board (IEC/IRB/REB) approved informed consent formXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an informed consent form. A legally authorized representative may consent on behalf of a subject who is otherwise unable to provide informed consent, if acceptable to, and approved by, the site's Institutional Review Board (IRB)/Independent Ethics Committee (IEC).Xx_NEWLINE_xXParticipant must voluntarily sign and date an informed consent, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to the initiation of any screening or study-specific procedures.Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks, and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSigned informed consent approved by the Institutional Review BoardXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board/Independent Ethics Committee (IRB/IEC) approved written informed consent form in accordance with regulatory and institutional guidelines. This must be obtained before the performance of any protocol related procedures that are not part of normal subject care.Xx_NEWLINE_xXWilling to sign consent onto the Mayo Clinic Radiotherapy Patient Outcomes Registry and Biobanking study, Institutional Review Board (IRB) number 15-000136 (blood draw optional)Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXhave read, understood and signed the informed consent form (ICF) approved by the Institutional Review Board (IRB);Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXSigned an institutional review board (IRB)-approved informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorizationXx_NEWLINE_xXIndividuals able to understand and willing to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must also provide written consent for biospecimens collection on Institutional Review Board (IRB) 08-000980Xx_NEWLINE_xXWritten informed consent to participate in the study according to the investigational review board (IRB)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board (IRB)/Independent Ethics Committee (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject careXx_NEWLINE_xXMust be fully informed regarding their illness and the investigational nature of the study protocol, and must sign an Institutional Review Board (IRB) approved Informed Consent Form (ICF).Xx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board/Independent Ethics Committee (IRB/IEC) approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject careXx_NEWLINE_xXParticipant must voluntarily sign and date an informed consent form, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to the initiation of any screening or study-specific procedures.Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXVoluntarily sign and date an informed consent form (ICF) with authorization to use protected health information (in accordance with national and local subject privacy regulations) and approved by the Institutional Review Board (IRB) prior to initiation of any study specific proceduresXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator’s Institutional Review Board (IRB)/Ethics CommitteeXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatient must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator’s Institutional Review Board (IRB)/Ethics CommitteeXx_NEWLINE_xXA signed informed consent form approved by the Institutional Review Board (IRB) will be required for patient enrollment into the study; patients must be able to read and understand the informed consent document and must sign the informed consent indicating that they are aware of the investigational nature of this studyXx_NEWLINE_xXPatient is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board (IRB)-approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol-related procedures that are not part of normal subject careXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved, written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXVoluntary signed and dated Institutional Review Board (IRB) approved informed consent form in accordance with regulatory and institutional guidelinesXx_NEWLINE_xXWritten consent on an Institutional Review Board-approved informed consent form prior to any study-specific evaluationXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written consent form approved by the investigator’s Institutional Review Board (IRB)/ethics committeeXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatients must sign the Institutional Review Board (IRB)-approved informed consent document for this trialXx_NEWLINE_xXVoluntary signed and dated Institutional Review Board (IRB) approved informed consent form in accordance with regulatory and institutional guidelinesXx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB)-approved written informed consent document (legally authorized representative permitted)Xx_NEWLINE_xXBe able to give written Institutional Review Board (IRB) approved informed consent and be able to follow protocol requirementsXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and provide signed informed consent that fulfills Institutional Review Board (IRB) guidelinesXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXSigned informed consent approved by the Institutional Review BoardXx_NEWLINE_xXPatient must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXDONOR: Able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXPatient or durable power of attorney (DPA) for healthcare must be able to understand and voluntarily sign an Institutional Review Board (IRB) -approved informed consent formXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXPatients must have signed and dated an Institutional Review Board (IRB) approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject careXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatient is unwilling or unable to sign and date the Institutional Review Board (IRB) approved informed consentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXSubjects must sign and date an Institutional Review Board-approved informed consent form (including Health Insurance Portability and Accountability Act authorization, if applicable) before performance of any study-specific procedures or testsXx_NEWLINE_xXSigned informed consent approved by the Institutional Review Board prior to patient entryXx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks, and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXSigned informed consent approved by the Institutional Review Board prior to patient entryXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXUnderstand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must voluntarily provide written Institutional Review Board (IRB)-approved informed consentXx_NEWLINE_xXSign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an institutional review board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAll patients must sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXSubject must sign and date an Institutional Review Board-approved informed consent form (including Health Insurance Portability and Accountability Act authorization, if applicable) before performance of any study-specific procedures or tests.Xx_NEWLINE_xXThe patient or, if applicable, her legally authorized representative must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXPatients will sign an Institutional Review Board (IRB)-approved informed consent form prior to any study-related proceduresXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatient understands the study regimen, its requirements, risks and discomforts and is able and willing to sign the informed consent form; voluntary signed and dated Institutional Review Board (IRB)/Independent Ethics Committee (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines must be obtained before the performance of any protocol related procedures that are not part of normal patient careXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's IRB/Ethics CommitteeXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator’s Institutional Review Board (IRB)/Ethics CommitteeXx_NEWLINE_xXSigned informed consent approved by the Institutional Review BoardXx_NEWLINE_xXMentally competent, ability to understand and willingness to sign an Institutional Review Board (IRB)-approved written informed consent formXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and provide signed informed consent that fulfills Institutional Review Board’s guidelinesXx_NEWLINE_xXRelapsed/refractory MCL: Understand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXThe subject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent prior to receiving any study related procedureXx_NEWLINE_xXPatients must be able to understand and agree to sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAll patients must sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXUnderstanding and voluntarily signing an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXCo-enrollment on Institutional Review Board (IRB) #98117, entitled Molecular Pathogenesis of Therapy-Related Leukemia, Dr. Armenian, principal investigatorXx_NEWLINE_xXWritten informed consent and/or Consent waiver by institutional review board (IRB)Xx_NEWLINE_xXInstitutional Review Board (IRB)-/Independent Ethics Committee (IEC)-approved written Informed Consent and privacy language as per national regulations must be obtained from the subject or legally authorized representative prior to any study-related proceduresXx_NEWLINE_xXInstitutional Review Board (IRB)-approved informed consent obtained and signedXx_NEWLINE_xXAll patients must sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXSubjects must give institutional review board (IRB)-approved study-specific informed consentXx_NEWLINE_xXUnderstand and sign, written Institutional Review Board (IRB)-approved informed consent form, and be willing to comply with all study proceduresXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatients must have signed informed consent both for this study and the research use of data in the UAB bone marrow transplantation (BMT) program's Institutional Review Board (IRB) registered clinical databaseXx_NEWLINE_xXSigned and dated institutional review board (IRB)/independent ethics committee (IEC)-approved informed consent form (ICF) before any study specific screening procedures are performedXx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent document (either directly or via a legally authorized representative)Xx_NEWLINE_xXPatients must be able to understand and agree to sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable).Xx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consents, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXFOR TISSUE COLLECTION TO ESTABLISH PDX (PART 1): Understand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent form.Xx_NEWLINE_xXAbility to understand and willingness to sign an institutional review board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable).Xx_NEWLINE_xXParticipant is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to initiation of any screening or study-specific proceduresXx_NEWLINE_xXSigned, written Institutional Review Board (IRB)-approved informed consent form (ICF)Xx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXParticipants must have signed and dated an Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol-related procedures that are not part of normal patient careXx_NEWLINE_xXAll patients or their legal guardians (if the patient is < 18 years old) must sign an Institutional Review Board (IRB)-approved document of informed consent to demonstrate their understanding of the investigational nature and the risks of this study before any protocol-related studies are performed; when appropriate, pediatric subjects will be included in all discussionsXx_NEWLINE_xXAbility to understand and the willingness to sign a written Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must understand and be willing to sign an informed consent form approved for this purpose by the Institutional Review Board (IRB) of the University of Michigan Medical Center indicating that they are aware of the investigational aspects of the treatment and the potential risksXx_NEWLINE_xXDONOR: The donor or legal guardian greater than 18 years of age, capable of signing an Institutional Review Board (IRB)-approved consent formXx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB)-approved written informed consent documentXx_NEWLINE_xXAll patients must be informed about the study and have signed a current Institutional Review Board (IRB) approved informed consentXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXInformed consent: all subjects must have the ability to understand and the willingness to sign an Institutional Review Board (IRB) approved consent formXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving and study related procedureXx_NEWLINE_xXPatient (or legally authorized representative if applicable) must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXUnderstand and sign an IRB/IEC-approved ICF prior to any study-specific evaluationXx_NEWLINE_xXAbility to understand and sign an Independent Ethics Committee- or Institutional Review Board-approved informed consent document indicating that the subject (or legally acceptable representative) has been informed of all aspects of the trial and is willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures. The informed consent document must be signed prior to the subject undergoing tests or procedures solely for determining study eligibility and prior to receiving any protocol treatment.Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXSubjects who voluntarily signed and dated Institutional Review Board approved informed consent form in accordance with regulatory and institutional guidelines. Hepatocellular Carcinoma Inclusion Criteria:Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXUnderstanding and voluntary signing an institutional review board (IRB)-approved informed consent formXx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXAble to understand and willing to sign Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (legally authorized representative is allowed)Xx_NEWLINE_xXPatients must exercise informed voluntary consent and sign a consent form approved by the University of Minnesota Institutional Review Board (IRB): Human Subjects CommitteeXx_NEWLINE_xXAbility to understand and provide signed informed consent that fulfills Institutional Review Board (IRB)’s guidelinesXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and sign the Institutional Review Board (IRB)-approved informed consent document for this trialXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an institutional review board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAble to understand and be willing to sign an Institutional Review Board (IRB) approved written informed consent document (or legally authorized representative, if applicable)Xx_NEWLINE_xXHas read, understood and signed the informed consent form (ICF) approved by the Institutional Review Board/Independent Ethics Committee (IRB/IEC).Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board (IRB)/Institutional Ethics Committee (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject careXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXSigned informed consent approved by the Institutional Review BoardXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXProvided written informed consent and HIPAA authorization for release of personal health information, approved by an Institutional Review Board/Independent Ethics Committee (IRB/IEC).Xx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's Institutional Review Board (IRB)/Ethics CommitteeXx_NEWLINE_xXSubject must voluntarily sign and date an informed consent, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to the initiation of any screening or study-specific procedures.Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXUnderstand and voluntarily sign an institutional review board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXSubject must be able to understand and willing to sign an informed consent. A legally authorized representative may consent on behalf of a subject who is otherwise unable to provide informed consent, if acceptable to and approved by the site and/or site's Institutional Review Board (IRB).Xx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document that is approved by an institutional review boardXx_NEWLINE_xXSigned and dated institutional review board (IRB)/independent ethics committee (IEC)-approved informed consent form (ICF) before any study specific screening procedures are performedXx_NEWLINE_xXSigned an informed consent document that has been approved by an institutional review board or independent ethics committee (IRB/IEC).Xx_NEWLINE_xXMentally competent, ability to understand and willingness to sign an Institutional Review Board (IRB)-approved written informed consent formXx_NEWLINE_xXWritten informed consent to participate in the study according to the Investigational Review Board (IRB)Xx_NEWLINE_xXSubjects must be able to understand and willing to sign an informed consent. A legally authorized representative may consent on behalf of a subject who is otherwise unable to provide informed consent, if acceptable to and approved by the site and/or sites Institutional Review Board (IRB)/Independent Ethics Committee (IEC).Xx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and willingness to sign a written informed consent document (approved by Institutional Review Board or independent ethics committee) obtained prior to any study procedure, with the understanding that the subject may withdraw at any time without prejudiceXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent document (legally authorized representative permitted)Xx_NEWLINE_xXSigned, Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXParticipants must sign the most current institutional review board (IRB)-approved study informed consent form (ICF)Xx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSigned informed consent approved by the Institutional Review Board prior to patient entryXx_NEWLINE_xXSigned informed consent approved by the Institutional Review Board prior to patient entryXx_NEWLINE_xXUnderstand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXSign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXPatient must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks, and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXPatient must be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXPatient (or legally authorized representative if applicable) must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXSigned an Institutional Review Board (IRB)-approved informed consent document for this protocolXx_NEWLINE_xXSigned an institutional review board (IRB)-approved informed consent document for this protocolXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed-consent document that is approved by the local institutional review boardXx_NEWLINE_xXPatient must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure.Xx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXA signed informed consent form approved by the Duke University Institutional Review Board (IRB) will be required for patient enrollment into the study; patients must be able to read and understand the informed consent document and must sign the informed consent indicating that they are aware of the investigational nature of this studyXx_NEWLINE_xXOptional participation in the microdose imaging trial, Institutional Review Board (IRB)#10-139Xx_NEWLINE_xXPatients must be informed of the experimental nature of the study and its potential risks and must sign an institutional review board (IRB)-approved written informed consent form indicating such an understandingXx_NEWLINE_xXE 14. Absence of signed and dated Institutional Review Board (IRB)-approved participant informed consent form prior to enrollment into the study.Xx_NEWLINE_xXSigned, Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXSigned, Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXSubject or legally authorized representative of a subject must provide signed informed consent document that has been approved by an Institutional Review Board or Independent Ethics Committee (IRB/IEC) prior to initiation of any study-related tests or procedures that are not part of standard-of-care for the subject’s diseaseXx_NEWLINE_xXAbility to understand and provide signed informed consent approved by the Institutional Review Board prior to any study-related activities and within 30 days of first study doseXx_NEWLINE_xXWritten informed consent to participate in the study according to the investigational review board (IRB) or independent ethics committee (IEC)Xx_NEWLINE_xXPatients must agree to randomization as documented by signing the Institutional Review Board (IRB) approved consent formXx_NEWLINE_xXPatients or a legal guardian will sign an informed consent form approved by the Institutional Review Board (IRB) and obtained by the principal or a co-investigator before patient entry; minors will provide assentXx_NEWLINE_xXCompetent to comprehend, sign, and date an IRB-approved informed consent formXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consent, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXThis study must be evaluated and confirmed by the local ethics committees and institutional review board of the participating institution, in accordance to the declaration of Helsinki; informed consent must be administered and the parent or guardian must sign the document, authorized by the Ethics Committee and human subjects (therapy cannot start if the documents is not signed)Xx_NEWLINE_xXSigned written informed consent\r\n* Subjects must have signed and dated an Institutional Review Board (IRB)/Independent Ethics Committee (IEC) approved written informed consent form in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject care\r\n* Subjects must be willing and able to comply with scheduled visits, treatment schedule, and laboratory testingXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatients must sign an informed consent form approved for this purpose by the Institutional Review Board (IRB) of the University of Michigan Medical Center indicating that they are aware of the investigational aspects of the treatment and the potential risksXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXUnderstand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an independent ethics committee/institutional review board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXWilling to sign an Institutional Review Board (IRB)-approved informed consent document and adhere to the protocolXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's Regional Ethics Board/Independent Ethics Committee (REB/IEC)Xx_NEWLINE_xXUnderstand and voluntarily sign an Institutional Review Board (IRB) approved informed consent formXx_NEWLINE_xXSigned and dated institutional review board (IRB)-approved informed consent before any protocol-specific screening procedures are performed.Xx_NEWLINE_xXHas read, understood and signed the informed consent form (ICF) approved by the Independent Review Board/Independent Ethics Committee (IRB/IEC); andXx_NEWLINE_xXSubjects must have signed and dated an Institutional Review Board/Independent Ethics Committee (IBR/IEC) approved written informed consent form in accordance with regulatory and institutional guidelinesXx_NEWLINE_xXSigned and dated Institutional Review Board (IRB)-approved consent formXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure. Expansion part:Xx_NEWLINE_xXProvide written informed consent for study participation, approved by the appropriate institutional review board (IRB), and be willing and able to cooperate with all aspects of the protocol;Xx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and able to sign and date the informed consents, approved by the Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXSign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must have signed and dated an Institutional Review Board/Independent Ethics Committee -approved written informed consent form in accordance with regulatory and institutional guidelines. This must be obtained before the performance of any protocol-related procedures that are not part of normal patient careXx_NEWLINE_xXWritten informed consent on an Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved ICF before any study-specific evaluationXx_NEWLINE_xXPatients or their legal representative must be able to read (or have read to them), understand, and sign a written informed consent (approved by the institutional review board) within 14 days prior to start of treatment.Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXUnderstanding and voluntary signing an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXFully informed about their illness and the investigational nature of the study protocol and must sign and date an Institutional Review Board-approved Informed Consent FormXx_NEWLINE_xXAbsence of signed and dated Institutional Review Board-approved patient informed consent from prior to enrollment in the studyXx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXPatient (or legally authorized representative if applicable) must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXBe able and willing to sign informed consent document that has been approved by an institutional review board or independent ethics committee (IRB/IEC)Xx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject must be capable of understanding and complying with parameters as outlined in the protocol and able to sign informed consent, approved by an Institutional Review Board (IRB) prior to the initiation of any screening or study specific procedures.Xx_NEWLINE_xXMust voluntarily sign and date each informed consent, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to the initiation of any screening or study-specific procedures.Xx_NEWLINE_xXSubject must voluntarily sign and date an informed consent, approved by an Independent Ethics Committee (IEC)/Institutional Review Board (IRB), prior to the initiation of any screening or study-specific proceduresXx_NEWLINE_xXSign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXSign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to read, understand, and sign a written informed consent approved by each Institutional Review Board (IRB); alternatively, patients with legal guardians who can read, understand, and sign written informed consent may also enrollXx_NEWLINE_xXSubject is capable of understanding and complying with parameters as outlined in the protocol and the subject or the subject's legal acceptable representative is able to sign informed consent, approved by an Institutional Review Board (IRB) prior to the initiation of any or study-specific procedures.Xx_NEWLINE_xXCompetent to sign and date an Institutional Review Board approved informed consent formXx_NEWLINE_xXPatients must have signed the current Institutional Review Board (IRB) approved informed consent prior to registration (see Informed Consent).Xx_NEWLINE_xXPatients must sign an Institutional Review Board (IRB) approved informed consent form for this purpose indicating that they are aware of the investigational aspects of the treatment and the potential risks; they also must be able to understand and the willing to sign a written informed consentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB), approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatient or durable power of attorney (DPA) for healthcare must be able to understand and voluntarily sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAbility to understand and the willingness to sign the Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an institutional review board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXInstitutional Review Board (IRB) approved, signed written informed consentXx_NEWLINE_xXSigned, Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAble to understand and willing to sign Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXInstitutional review board (IRB) approved signed written informed consentXx_NEWLINE_xXAble to understand and sign an Institutional Review Board (IRB)-approved informed consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble and willing to sign an Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXSigned informed consent approved by the Duke Institutional Review BoardXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXSigned informed consent approved by the Institutional Review Board prior to patient entryXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent document (either directly or via a legally authorized representative)Xx_NEWLINE_xXInstitutional Review Board (IRB) approved, signed written informed consentXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXInstitutional Review Board (IRB) approved signed written informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSigned Institutional Review Board (IRB) approved written informed consentXx_NEWLINE_xXMust be competent and able to comprehend, sign, and date an Ethics Committee (EC) or Institutional Review Board approved Informed Consent Form (ICF) before performance of any study-specific procedures or tests;Xx_NEWLINE_xXSubjects must have signed and dated an institutional review board (IRB) approved written informed consent in accordance with regulatory and institutional guidelines; this must be obtained before the performance of any protocol related procedures that are not part of normal subject careXx_NEWLINE_xXAll patients must sign an informed consent form approved for this purpose by the Institutional Review Board (IRB) of the University of PennsylvaniaXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatient must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatient (or legally authorized representative if applicable) must be able to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXSigned an Institutional Review Board (IRB)-approved informed consentXx_NEWLINE_xXSigned written informed consent approved by the Institutional Review Board obtained prior to study entryXx_NEWLINE_xXThe study has been explained to the patient/volunteer and the subject has signed the Institutional Review Board (IRB)-approved informed consent form prior to optical measurementsXx_NEWLINE_xXSubject must understand the investigational nature of this study and sign an Independent Ethics Committee/ Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXA signed informed consent form approved by the Duke University Institutional Review Board (IRB) will be required for patient enrollment into the study. Patients or their legally authorized representative (LAR) must be able to read and understand the informed consent document and must sign the informed consent indicating that they are aware of the investigational nature of this study. Treating physicians at the time the protocol is presented are able to determine based on their clinical judgment whether patients lack the capacity and require a LAR to sign the consent formXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXAble to and provides Institutional Review Board (IRB) approved study specific written informed consentXx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXWilling and able to understand and sign informed consent form approved by the institutional review board (IRB)Xx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document that is approved by the local institutional review boardXx_NEWLINE_xXSubject must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAre able to give written informed consent in a manner approved by the Institutional Review Board and comply with the requirements of the study.Xx_NEWLINE_xXPatient must consent to be in the study and must have signed and dated an Institutional Review Board (IRB) approved consent form conforming to federal and institutional guidelinesXx_NEWLINE_xXMust be able and willing to sign an informed consent approved by the Institutional Review Board (IRB)Xx_NEWLINE_xXThe patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelinesXx_NEWLINE_xXTNBC patients who are previously untreated and enrolled in the prospective Institutional Review Board (IRB) approved clinical trial: 2014-0185Xx_NEWLINE_xXConsent: patients must be able to give written, informed consent as approved by the local Institutional Review Board (IRB)Xx_NEWLINE_xXInformed consent signed by participant, parent, or guardian according to the guidelines of the institutional review boardXx_NEWLINE_xXMust be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent\r\ndocumentXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXHave read and signed the Institutional Review Board (IRB)-approved informed consent form for participating in the studyXx_NEWLINE_xXWill sign the Institutional Review Board (IRB)-approved consent formXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXWomen must be enrolled in Atlanta Women’s human immunodeficiency virus (HIV) Interagency Study (WIHS) (institutional review board [IRB] # 00062469)Xx_NEWLINE_xXParticipant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPATIENT: Have read and signed the Institutional Review Board (IRB)-approved informed consent form for participating in the studyXx_NEWLINE_xXLegally authorized representative/guardian must be able to understand and willing to sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must understand and be willing to sign an informed consent form approved for this purpose by the Institutional Review Board (IRB) of the University of Michigan Medical Center indicating that they are aware of the investigational aspects of the treatment and the potential risksXx_NEWLINE_xXAll patients or their legal guardians (if the patients is < 18 years old) must sign an Institutional Review Board (IRB)-approved document of informed consent to demonstrate their understanding of the investigational nature and the risks of this study before any protocol-related studies are performed; when appropriate, pediatric subjects will be included in all discussionsXx_NEWLINE_xXWritten informed consent will be signed by the patients before the MRI based on the guidelines approved by the Ohio State University Institutional Review boardXx_NEWLINE_xXInformed consent signed by participant, parent, or guardian according to the guidelines of the institutional review boardXx_NEWLINE_xXINCLUSION CRITERIA FOR OPEN-ACCESS: Informed consent signed by participant, parent, or guardian according to the guidelines of the institutional review boardXx_NEWLINE_xXSigned, Institutional Review Board (IRB)-approved written informed consentXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXParticipant must be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXInstitutional Review Board (IRB) written informed consent obtained and signedXx_NEWLINE_xXPatients must sign an Institutional Review Board (IRB)-approved informed consent documentXx_NEWLINE_xXSubjects must have signed Institutional Review Board (IRB)-approved informed consent documentationXx_NEWLINE_xXSubjects must have signed an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXPatients must sign an institutional review board (IRB)-approved informed consent documentXx_NEWLINE_xXSubjects (or their parent or legal guardian) must have signed Institutional Review Board (IRB)-approved assent/informed consent documentationXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB) approved written informed consent documentXx_NEWLINE_xXAbility to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's Institutional Review Board (IRB)/Ethics CommitteeXx_NEWLINE_xXSubject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXPatient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXParticipant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedureXx_NEWLINE_xXAre fully informed about their illness and the investigational nature of the study protocol (including foreseeable risks and possible side effects) and must sign and date an Institutional Review Board (IRB)-approved informed consent form (ICF), including Health Insurance Portability and Accountability Act authorization, if applicable, before performance of any study-specific procedures or testsXx_NEWLINE_xXPatient: Able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign an Institutional Review Board (IRB) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXBe Institutional Review Board (IRB)-approved and open to accrual at USC NorrisXx_NEWLINE_xX