Able to provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXSubject or subject's representative is willing and able to provide written informed consentXx_NEWLINE_xXWilling and able to give written informed consent.Xx_NEWLINE_xXPatient is able and willing to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXPatient must be capable, willing, and able to provide written, informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consent.Xx_NEWLINE_xXPatients must be able to understand and provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble to give a written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXAble to provide informed consent, or have a legal representative able and willing to do soXx_NEWLINE_xXAble and willing to give informed consentXx_NEWLINE_xXPatients must be able to give adequate informed consentXx_NEWLINE_xXCOHORT 1: Be willing and able to provide written informed consent / assent for the trialXx_NEWLINE_xXCOHORT 2: Be willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide valid written informed consentXx_NEWLINE_xXAble to provide informed consent prior to initiation of studyXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble and willing to give valid written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble to understand the nature of this trial and provide written informed consentXx_NEWLINE_xXAble to provide confirmed consentXx_NEWLINE_xXWilling and able to provide written Informed Consent and comply with the requirements of the study.Xx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXPatients or their legal representative must be able to provide written informed consent;Xx_NEWLINE_xXSubject should be able to provide written informed consent, comply with protocol visits and procedures, be able to take oral medication, and not have any active infection or comorbidity that would interfere with therapy.Xx_NEWLINE_xXTREATMENT: Patient able to give informed consentXx_NEWLINE_xXAble and willing to provide written informed consent to participate in this study.Xx_NEWLINE_xXPatient, parent, or legal guardian must be able to understand and be willing to provide informed consentXx_NEWLINE_xXWilling and able to provide written informed consent for the studyXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble and willing to provide written, signed informed consent (assent as appropriate)Xx_NEWLINE_xXDONOR: Able and willing to provide written, signed informed consent (assent as appropriate)Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAre willing and able to provide signed informed consent.Xx_NEWLINE_xXPatients must be able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent for the trialXx_NEWLINE_xXAble to understand and comply with the requirements of the study and to provide written informed consent or age appropriate assent for pediatric patients.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXThe subject or their legal guardian be willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to give written, and dated, informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consent to participate in this investigational study.Xx_NEWLINE_xXPatients must be able to provide informed consent.Xx_NEWLINE_xXSubject is willing and able to give prior written informed consent for investigation participation; andXx_NEWLINE_xXPatients who are able to give informed consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXPatients must be of appropriate mental capacities with sufficient social support so as to be able to complete required study activities (i.e. diet record, etc) and able to provide written informed consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXAble to give written informed consent.Xx_NEWLINE_xXPatients must be able to understand and provide written informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXPART I: Able to understand and provide informed consentXx_NEWLINE_xXPART II: Able to understand and provide informed consentXx_NEWLINE_xXPatients or their legal representatives must be able to comprehend and provide written informed consentXx_NEWLINE_xXMust be able and willing to give written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trial.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trial and comply with the study visit requirementsXx_NEWLINE_xXARM I&II: Patients must be able to provide written informed consentXx_NEWLINE_xXAble to provide written, informed consent before initiation of any study related procedures, and is able, in the opinion of the Investigator, to comply with all the requirements of the study.Xx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXThe participant (or legally authorized representative, if applicable) must be willing and able to provide written informed consent for the trialXx_NEWLINE_xXIs able to provide written informed consent (in English) to participate in the study and able to understand the procedures and study requirementsXx_NEWLINE_xXWilling and able to provide informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirementsXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trial.Xx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXPatient, parent, or legal guardian must be able to understand and willing to provide informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXMust be able and willing to participate in all aspects of the study and provide informed consent prior to study participation.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trial.Xx_NEWLINE_xXDonors must be able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trial.Xx_NEWLINE_xXPatients must be able to provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trial.Xx_NEWLINE_xXPatient must be willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXHEALTHY SUBJECT: Be willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to understand and give written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the studyXx_NEWLINE_xXPatients are able to understand and provide written informed consent prior to trial participationXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXParticipants must be able to provide informed consent for treatment and trial participationXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble to provide informed consent and be willing to participate in study schedule and events.Xx_NEWLINE_xXWilling and able to provide written informed consent.Xx_NEWLINE_xXMust be able to provide written informed consent before any screening procedures.Xx_NEWLINE_xXAble to provide written informed consent for the trialXx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before study enrollmentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXAbility to provide signed informed consent and willing and able to comply with all study requirementsXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent prior to performance of any study-specific proceduresXx_NEWLINE_xXAble to provide informed consent and comply with all study protocolsXx_NEWLINE_xXAble to provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consent for the trialXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to understand and give written informed consent and comply with all study related proceduresXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide valid written informed consent.Xx_NEWLINE_xXBe willing and able to provide written consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXSubjects must be willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent prior to initiation of any study proceduresXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXIs willing and able to provide written informed consent for the trial.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXSubjects must be able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXSubjects must be able to provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble and willing to give valid written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXAble and willing to provide informed consent and to comply with the study proceduresXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXWilling and able to provide consentXx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to provide consentXx_NEWLINE_xXBe willing and able to provide written informed consent for trialXx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before study enrollmentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatient able and willing to provide informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trial.Xx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatient able to provide written informed consent; parent or guardian of minor patient able to provide written informed consentXx_NEWLINE_xXAble and willing to provide written informed consent prior to performing any study-related procedures and to comply with the study protocol, including patients must be willing and able to use the electronic patient-reported outcome (ePRO) deviceXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXMust be willing and able to participate and comply with all trial requirements and able to provide signed and dated informed consent prior to initiation of any trial proceduresXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXSubject must provide written informed consent and be willing and able to comply with all aspects of the protocolXx_NEWLINE_xXPatients must be able to comprehend and provide written informed consentXx_NEWLINE_xXPatient able to give informed consentXx_NEWLINE_xXSubject or a legal guardian is able to voluntarily provide written informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatient or patient’s legal representative able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXEither the subject or the subject’s legal representative must be willing and able to provide written informed consent for the trialXx_NEWLINE_xXIs willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related proceduresXx_NEWLINE_xXWilling and able to provide written informed consent prior to initiation of any study-related proceduresXx_NEWLINE_xXMust be able and willing to give written informed consentXx_NEWLINE_xXBe able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatient must be capable, willing, and able to provide written, informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXTREATMENT: Patient able to give informed consentXx_NEWLINE_xXPatient or patient’s legal representative, parent(s), or guardian able to provide written informed consentXx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXPatient or patient’s legal representative, parent(s) or guardian able to provide written informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXBe able and willing to give informed consentXx_NEWLINE_xXSubjects must be able to provide written informed consentXx_NEWLINE_xXPatients should be willing and able to give informed consentXx_NEWLINE_xXPatients are willing and able to give informed consent (Phase II only)Xx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXAble and willing to provide written informed consent and to comply with the study protocolXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXPatients must agree to participate and be able to understand and provide informed consent to participate in the trialXx_NEWLINE_xXPatient must be able to provide written informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXWilling and able to comply with the study procedures and provide written informed consent to participate in the studyXx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXDONOR: Able to give informed consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXPatients must be able to provide written-informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXPatients must have the ability able to give informed consentXx_NEWLINE_xXAble and willing to give informed consent.Xx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXEligibility criteria specific to the control arm:\r\n* Participants must be willing and able to provide written informed consent/assent for the control arm of the INdividualized Screening trial of Innovative Glioblastoma Therapy (INSIGhT) trialXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXpatients who are able to give informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent.Xx_NEWLINE_xXBe able and willing to provide written informed consent and to comply with all requirements of study participation (including all study procedures);Xx_NEWLINE_xXParticipant must be able to provide written Informed ConsentXx_NEWLINE_xXPatients are not able to provide written informed consent to study participationXx_NEWLINE_xXBe willing and able to provide written informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXAble and willing to give valid written informed consent.Xx_NEWLINE_xXAble to understand and willing to provide written informed consent.Xx_NEWLINE_xXPatients who are able and willing to give consent and able to attend all study visitsXx_NEWLINE_xXAble and willing to give informed consent.Xx_NEWLINE_xXAble and willing to give informed consent.Xx_NEWLINE_xXAble to understand and provide informed consentXx_NEWLINE_xXWilling and able to consent for self to participate in studyXx_NEWLINE_xXAble to give informed consent.Xx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXAble and willing to provide informed consentXx_NEWLINE_xXAble to provide signed, written informed consentXx_NEWLINE_xXPatient able to provide written informed consent.Xx_NEWLINE_xXPatient able to provide written informed consent for the long-term follow-up (LTFU) gene therapy study.Xx_NEWLINE_xXMust be able to provide informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trial.Xx_NEWLINE_xXWilling and able to give informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to give informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXMust be able and willing to give written informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble and willing to give valid written informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXSubjects or their legal representative must be able to understand and provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent for voluntary participation in the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXParticipant is willing and able to give written informed consentXx_NEWLINE_xXPatient is willing and able to give written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the studyXx_NEWLINE_xXThey must be able to provide informed consentXx_NEWLINE_xXPatients must be able to give informed consentXx_NEWLINE_xXPatients must be able to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to give informed written consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXSubjects or their legal representatives must be able to provide written informed consent.Xx_NEWLINE_xXAble and willing to provide written informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatient willing and able to provide written informed consentXx_NEWLINE_xXPatients or their legal representative (if the patient is < 18 years old) must be able to read, understand and provide written informed consent to participate in the trial.Xx_NEWLINE_xXAble to give a written informed consent.Xx_NEWLINE_xXWilling and able to give written informed consent and comply with study visit scheduleXx_NEWLINE_xXPatients, or appropriate designee, must be able to provide informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXMust be able and willing to give written informed consentXx_NEWLINE_xXAble and willing to provide written informed consent to participate in the studyXx_NEWLINE_xXWilling and able to give written informed consent and comply with study visit schedule.Xx_NEWLINE_xXAble and willing to provide written informed consent and to comply with the study protocolXx_NEWLINE_xXAble and willing to provide consent for required bone marrow biopsies.Xx_NEWLINE_xXAble and willing to give valid written informed consentXx_NEWLINE_xXPatients must be able and willing to give written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trial and comply with the study visit requirementsXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXBe willing and able to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trial.Xx_NEWLINE_xXDONOR: Willing and able to provide informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXAble to provide written informed consent and to follow protocol requirements.Xx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirementsXx_NEWLINE_xXSubjects must be able to understand the potential risks and benefits of the study, and be able to read and give written informed consentXx_NEWLINE_xXMust be willing and able to provide written informed consentXx_NEWLINE_xXWilling and able to give written informed consent.Xx_NEWLINE_xXWilling and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trial; consent may be obtained by legally authorized representative (LAR) according to the protocolXx_NEWLINE_xXWilling and able to provide informed written consentXx_NEWLINE_xXSubjects must be able to give informed consentXx_NEWLINE_xXPatient or patient’s legal representative able to provide written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble and willing to provide written informed consentXx_NEWLINE_xXEither the subject or his/her legally authorized representative be willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble and willing to give valid written informed consent.Xx_NEWLINE_xXAble to provide informed written consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirementsXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXPatients, or appropriate designee, must be able to provide informed consentXx_NEWLINE_xXSubject is able to provide written informed consent.Xx_NEWLINE_xXAble to provide informed written consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXWilling and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related proceduresXx_NEWLINE_xXPatient should be able to provide informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXCOHORT A: The subject must be willing and able to provide informed consentXx_NEWLINE_xXCOHORT B: The subject must be willing and able to provide informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble and willing to give valid written informed consent.Xx_NEWLINE_xXPatient must be capable, willing, and able to provide written, informed consentXx_NEWLINE_xXFor adult patient, the patient is able to provide informed consent. For pediatric patient, a parent is able to provide informed consent.Xx_NEWLINE_xXPatient willing and able to provide written informed consent for the trialXx_NEWLINE_xXParticipants must be willing and able to review, understand, and provide written consent before starting any study-specific procedures or therapy.Xx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXSubjects must be able to give written consent to the studyXx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirements.Xx_NEWLINE_xXAble to provide informed consent and be willing to sign an informed consent formXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXBe willing and able to give written informed consent, and be able to comply with all study proceduresXx_NEWLINE_xXAble and willing to provide written informed consent.Xx_NEWLINE_xXPatients willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXAble to provide informed consent and follow protocol requirements.Xx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXAble to provide written, informed consentXx_NEWLINE_xXPatients must be willing and able to provide signed informed consent and comply with the study protocol.Xx_NEWLINE_xXPatient or guardian willing and able to provide informed consent.Xx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirementsXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatients must be able to give informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAble to provide informed consent for the studyXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXAble to give informed consent.Xx_NEWLINE_xXWilling and able to provide written Informed Consent and adhere to study procedures.Xx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXAble and willing to give valid written informed consent.Xx_NEWLINE_xXPatients or their legal representatives must be able to read, understand, and provide informed consent to participate in the trialXx_NEWLINE_xXSubjects must be able to understand the potential risks and benefits of the study and must be able to read and provide written, informed consent for the studyXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXSubjects must be able to understand the potential risks and benefits of the study and must be able to read and provide written, informed consent for the studyXx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirements.Xx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXAble to provide written informed consent.Xx_NEWLINE_xXPatients, or appropriate designee, must be able to provide informed consentXx_NEWLINE_xXAt least 18 years of age and willing and able to provide informed consent.Xx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXAble to understand and have the ability to provide written consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to provide written informed consent and to follow protocol requirementsXx_NEWLINE_xXWilling and able to provide written informed consent prior to performance of any study-specific proceduresXx_NEWLINE_xXAble to give informed written consentXx_NEWLINE_xXPatient, or his/her legally authorized representative, is able to understand and provide informed consent.Xx_NEWLINE_xXBe able to give informed consentXx_NEWLINE_xXWilling and able to provide written informed consent.Xx_NEWLINE_xXSubject should be able to provide written informed consent and comply with protocol visits and procedures.Xx_NEWLINE_xXSubject is able to voluntarily provide written informed consent.Xx_NEWLINE_xXSubjects between 12 and 35 years of age, inclusive, at the time of consent/assent, and able to provide written consent/assent, if applicable.Xx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXMust be willing and able to provide written informed consent and comply with the protocol and study proceduresXx_NEWLINE_xXAble and willing to give written informed consent.Xx_NEWLINE_xXAble to provide informed consent, child assent with parental consent or surrogate consent when applicableXx_NEWLINE_xX4. Patient is able and willing to provide written informed consent to participate in the study.Xx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXSubject or subject's representative is willing and able to provide written informed consentXx_NEWLINE_xXWilling and able to provide informed consent;Xx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to provide written informed consent obtained prior to participation in the study and any related procedures being performedXx_NEWLINE_xXBe willing and able to give written informed consent, and be able to comply with all study proceduresXx_NEWLINE_xXWilling and able to provide written informed consent prior to any study related procedures and to comply with all study requirements and for 3 months after last dose.Xx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXPatient must be able to give informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consent.Xx_NEWLINE_xXAble to understand and provide written informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to understand and provide written informed consentXx_NEWLINE_xXAble to provide written informed consent, and agree to practicing 2 forms of birth control during the studyXx_NEWLINE_xXWilling and able to give written informed consentXx_NEWLINE_xXBe able to provide written informed consentXx_NEWLINE_xXWilling to consent to randomization and able to participate in the studyXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to read either English or Spanish and able to provide written (via paper), verbal consent or on-line informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXBe able to provide informed consentXx_NEWLINE_xXPatient/partner is able to provide informed consentXx_NEWLINE_xXPatients who are able and willing to give consent and able to attend all study visitsXx_NEWLINE_xXAble to comprehend and provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatient able to provide his/her own written informed consent and speak EnglishXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPatients able to understand the nature of the study and who are willing to give written informed consent;Xx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXPATIENT & PARTNER: Able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXMust be able to provide own consentXx_NEWLINE_xXAble to give consentXx_NEWLINE_xXPATIENTS AND CAREGIVERS: Able to provide informed consent.Xx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPhase I: Able to provide informed consentXx_NEWLINE_xXPhase II: Able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to give written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPARTNER: Able to consent to the studyXx_NEWLINE_xXAble and willing to provide informed consentXx_NEWLINE_xXPATIENTS AND PARTNERS: Able to provide consentXx_NEWLINE_xXAdults who are able to provide informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXNot willing and able to provide informed consentXx_NEWLINE_xXAble and willing to give informed consentXx_NEWLINE_xXPatient or patient’s legal representative(s) is/are able to provide written informed consent to participateXx_NEWLINE_xXSubject is able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXFCGs: Able to provide informed consentXx_NEWLINE_xXPATIENTS: Not able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble and willing to give informed consentXx_NEWLINE_xXAble and willing to provide written consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXNot willing and able to provide informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXBe able to provide written informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPHASE I: Able to provide meaningful informed consentXx_NEWLINE_xXPHASE II: Able to provide meaningful informed consentXx_NEWLINE_xXWilling and able to provide signed, informed consentXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXSubjects able to provide informed consentXx_NEWLINE_xXAble and willing to provide consent (both)Xx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXPATIENT: Be able and willing to provide informed consentXx_NEWLINE_xXFAMILY CAREGIVER: Able and willing to consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAre able to give consentXx_NEWLINE_xXAre eligible if they are able to give consentXx_NEWLINE_xXAble and willing to provide informed consentXx_NEWLINE_xXSubject is willing and able to provide written informed consent. 5. Subject is willing and able to meet all study requirements, including follow-up visits and receiving study-related telephone calls.Xx_NEWLINE_xXPatients must be willing and able to review, understand, and provide written consentXx_NEWLINE_xXPatients willing and able to review, understand, and provide written consentXx_NEWLINE_xXPatients willing and able to review, understand, and provide written consent before starting therapyXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPatients who are willing and able to review, understand, and provide written consentXx_NEWLINE_xXWilling and able to provide, signed informed consentXx_NEWLINE_xXSubjects are able to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXThe subject must be willing and able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXCognitively able and willing to provide consentXx_NEWLINE_xXPatients must be willing and able to provide a written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble and willing to provide written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXBe able to provide informed consent in English or SpanishXx_NEWLINE_xXAble to provide informed consent in EnglishXx_NEWLINE_xXWilling to provide informed consent/assent for study participationXx_NEWLINE_xXWilling to provide informed consent/assent for study participationXx_NEWLINE_xXSubjects willing and able to provide consent to participating in the studyXx_NEWLINE_xXAble to provide verbal consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatients must be willing and able to provide written informed consent for the trialXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXAble to provide informed consent to participate in the studyXx_NEWLINE_xXAble to understand and willing to provide informed consent for the RPFNA’s and study participationXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXUnderstand the study procedures and able to provide informed consentXx_NEWLINE_xXAble and willing (or have legal representative) to understand the study and provide consentXx_NEWLINE_xXSubjects provide signed informed consent and confirm that they are able and willing to comply with all protocol requirements. Cohort A Only:Xx_NEWLINE_xXAble to give consentXx_NEWLINE_xXPatient must be able and willing to provide written informed consentXx_NEWLINE_xXThe patient is willing and able to provide informed consent.Xx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXAble to provide legally effective informed consentXx_NEWLINE_xXAre able to provide informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAble to provide written informed consent and willing to comply with protocol requirementsXx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXWillingness to participate in the study and able to provide informed consentXx_NEWLINE_xXPatients must be able to provide informed consentXx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXAble to provide informed consent and follow the study guidelinesXx_NEWLINE_xXPatient able and willing to provide informed consentXx_NEWLINE_xXThe subject is able and willing to comply with study procedures and provide signed and dated informed consentXx_NEWLINE_xXThe subject is able and willing to comply with study procedures and provide signed and dated informed consentXx_NEWLINE_xXPatient is able to provide written informed consent prior to study registrationXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAble to consent for the studyXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAll subjects must be able to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXThe subject is able and willing to comply with study procedures and provide signed and dated informed consentXx_NEWLINE_xXSubject/legal representative willing and able to provide written informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatients/subjects able to give informed consentXx_NEWLINE_xXPatient is able to give informed consent for this studyXx_NEWLINE_xXSubject is able to give informed consent for this studyXx_NEWLINE_xXSubject and/or guardian is able to provide written informed consent prior to study registrationXx_NEWLINE_xXAble to read or understand and provide informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPatient and/or guardian is able to provide written informed consent prior to study registrationXx_NEWLINE_xXPatient and/or guardian is able to provide written informed consent prior to study registrationXx_NEWLINE_xXPatient is able and willing to give valid written informed consentXx_NEWLINE_xXPatient and/or guardian is able to provide written informed consent prior to study registrationXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXAble to provide written informed consent.Xx_NEWLINE_xXAble to provide written consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXPatient and/or legal guardian able and willing to provide informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXSubjects able to provide informed consent and agree to comply with study proceduresXx_NEWLINE_xXAre able to provide informed consentXx_NEWLINE_xXSubject must be able and willing to give written informed consent for a contrast enhanced ultrasound study of the prostateXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXPatient must be able and willing to give informed consentXx_NEWLINE_xXAble to give informed consentXx_NEWLINE_xXPatient and/or guardian is able to provide written informed consent prior to study registrationXx_NEWLINE_xXSubjects must to able to provide informed written consent prior to study entryXx_NEWLINE_xXWilling and able to consent and participate in the study.Xx_NEWLINE_xXAble to understand and comply with study procedures, understand the risks involved, and provide written informed consent.Xx_NEWLINE_xXAble to provide written informed consent, comply with protocol visits and procedures, be able to take oral medication, and not have any active infection or comorbidity that would interfere with therapy.Xx_NEWLINE_xXWilling and able to provide informed written consentXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXThe patient must be willing and able to provide informed consentXx_NEWLINE_xXPatients must be able to provide written informed consentXx_NEWLINE_xXWilling and able to provide a written informed consentXx_NEWLINE_xXAble to give consentXx_NEWLINE_xXMust be able to provide a written informed consentXx_NEWLINE_xXThe subject is able and willing to comply with study procedures and provide signed and dated informed consentXx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXAble to provide written informed consent and willing to comply with protocol requirementsXx_NEWLINE_xXWilling and able to provide informed consentXx_NEWLINE_xXAre able to provide informed consentXx_NEWLINE_xXBe willing and able to provide informed consentXx_NEWLINE_xXNORMAL VOLUNTEERS: Be willing and able to provide informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXWomen who are not able to give consentXx_NEWLINE_xXWilling and able to provide written informed consentXx_NEWLINE_xXSubjects are required to be willing and able to provide written informed consentXx_NEWLINE_xXParticipants who are not able to understand or provide written informed consentXx_NEWLINE_xXWilling and able to give informed consentXx_NEWLINE_xXAble to provide informed consentXx_NEWLINE_xXWilling and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related proceduresXx_NEWLINE_xXThe patient must be able to give informed consentXx_NEWLINE_xXAble to provide informed consent to participate in the studyXx_NEWLINE_xXMust be able to provide informed consentXx_NEWLINE_xXPatients willing to give informed consentXx_NEWLINE_xXWilling and able to provide informed consent and fill out demographic, disease, and pain assessment questionnairesXx_NEWLINE_xXBe willing and able to provide written informed consent.Xx_NEWLINE_xXPatients must be able and willing to provide written informed consent prior to any study related procedure.Xx_NEWLINE_xXAble to provide written informed consent.Xx_NEWLINE_xXAble to provide written informed consentXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xXBe willing and able to provide written informed consent/assent for the trialXx_NEWLINE_xX