All patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consent.Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parent or legal guardian must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXEach patient’s parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatients or their legal representatives must be able to read, understand, provide and sign informed consent to participate in the trialXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXWilling to sign Informed Consent;Xx_NEWLINE_xXSubjects must be willing and able to sign the informed consent and comply with the study protocol.Xx_NEWLINE_xXAble to agree to and sign informed consent and to comply with the protocolXx_NEWLINE_xXAble to understand and sign an informed consent (or have a legal representative who is able to do so)Xx_NEWLINE_xXSubject is able to understand and willing to sign the ICF, according to institutional standards, prior to the initiation of any study related procedures;Xx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXInability to understand and sign informed consentXx_NEWLINE_xXWilling and able to comply with the protocol and sign informed consentXx_NEWLINE_xXPatients and donors must be able to sign consent forms (or if a minor the parent will sign); donors should be willing to donateXx_NEWLINE_xXCompetent to sign informed consentXx_NEWLINE_xXSubject must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXParticipant is able to understand and comply with study requirements and is willing to sign a written informed consent documentXx_NEWLINE_xXPIK3CA WILD TYPE COHORT (closed 03/17/2016): Able to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXPatient able to understand, sign, and date the written informed consent form at screening visit prior to any protocol-specific proceduresXx_NEWLINE_xXWilling and able to understand and sign an informed consent inform and to comply with all aspects of the protocol.Xx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXINCLUSION CRITERIA FOR REGISTRATION (HER2 MUTATION IDENTIFIED BY WASH U GPS LABORATORY): Able to understand and willing to sign an IRB approved written informed consent documentXx_NEWLINE_xXINCLUSION CRITERIA FOR REGISTRATION (HER2 MUTATION IDENTIFIED AT AN OUTSIDE CLIA CERTIFIED LOCATION): Able to understand and willing to sign an IRB approved written informed consent documentXx_NEWLINE_xXWilling and able to comply with the study procedure and sign a written informed consentXx_NEWLINE_xXPatient and/or legal guardian must sign informed consent for HSCT.Xx_NEWLINE_xXIn the haplo cohort, the donor and/or legal guardian must be able to sign informed consent documents.Xx_NEWLINE_xXAble to sign an informed consentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedure; subjects must be willing and able to comply with scheduled visits, treatment schedule, laboratory testing, and other study requirementsXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the studyXx_NEWLINE_xXSign informed consent.Xx_NEWLINE_xXPatients or their legal representative must be able to read, understand and sign an informed consentXx_NEWLINE_xXARM 2 - A: Able to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign written informed consent.Xx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXThe patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document, inclusive of assent where appropriate, according to institutional guidelinesXx_NEWLINE_xXINCLUSION CRITERIA FOR STRATUM C: The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document, inclusive of assent where appropriate, according to institutional guidelinesXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAre able to comprehend and willing to sign an informed consent formXx_NEWLINE_xXAge >18 and must be able to read, understand, and sign informed consentXx_NEWLINE_xXAll participants and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXWillingness to sign the healthy volunteer informed consent formXx_NEWLINE_xXPatients must be able to understand and sign informed consent formXx_NEWLINE_xXPatient (or legally authorized representative) must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXWilling and able to sign informed consentXx_NEWLINE_xXSubject must sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatients must be able to understand and give informed consentXx_NEWLINE_xXAble to understand, and willing to sign, a written informed consent document.Xx_NEWLINE_xXEach patient must be willing to participate as a research participant and must sign an informed consent form.Xx_NEWLINE_xXSign an Informed Consent Form (ICF);Xx_NEWLINE_xXPatient able to understand and willing to sign and date the written voluntary informed consent form (ICF) at screening visit prior to any protocol-specific proceduresXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects must be willing and able to provide informed consent. For patients < 18 years of age, their parents or legal guardians must sign a written informed consent. Assent, when appropriate, will be obtained according to institutional guidelines.Xx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study, including biomarkers, and are willing to participate in the studyXx_NEWLINE_xXWillingness to sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient must be able to comprehend and sign a written informed consent and be willing to comply with all study proceduresXx_NEWLINE_xXAll patients >= 18 years of age must sign a written informed consent; for patients < 18 years old, the patient’s parents or legal guardians must sign a written informed consent, unless the patient is an emancipated minor; childhood assent, when age appropriate as per institutional guidelines, should be signed by the participating patientXx_NEWLINE_xXAble to understand and voluntarily sign a written informed consent, and willing and able to comply with protocol requirementsXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXAll patients and/or a legal guardian must sign institutionally approved written informed consent and assent documentsXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXAdult patients must be able to understand and sign a written informed consent. For pediatric patients, the parent/legal guardian or representative must be able to understand and sign a written informed consent. Assent, when appropriate, will be obtained according to institutional guidelines.Xx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedure; subjects must be willing and able to comply with scheduled visits, treatment schedule, laboratory testing, and other study requirementsXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXParticipants must be able to understand and sign a written informed consent form and understand the importance of adherence to study treatment and protocol; in addition, participants must demonstrate a willingness to follow all study requirements, including the concomitant medication restrictions, throughout the studyXx_NEWLINE_xXSubject can understand and sign the informed consent document, can communicate with the investigator, and can understand and comply with the requirements of the protocol.Xx_NEWLINE_xXAbility to sign informed consentXx_NEWLINE_xXPatients are able to understand and willing to sign the informed consent.Xx_NEWLINE_xXAbility of subject or legally authorized representative (LAR) to understand and sign the written informed consent documentXx_NEWLINE_xXAll participants and/or their parents or guardians must sign a written informed consent.Xx_NEWLINE_xXAble to sign informed consentXx_NEWLINE_xXPatients or their legal representative must be able to read, understand, and sign a written informed consentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign informed consentXx_NEWLINE_xXAble to understand and sign the Informed Consent DocumentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXA legal parent/guardian or patient must be able to understand, and willing to sign, a written informed consent and assent document, as appropriateXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXPatient refuses to sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and voluntarily sign a written informed consent, and willing and able to comply with protocol requirementsXx_NEWLINE_xXSubjects who are able to understand and sign an informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document; subject has signed the informed consent (ICF) prior to any screening procedures being performed and is able to comply with protocol requirementsXx_NEWLINE_xXPatients must be able to understand and be willing to sign the written informed consent formXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXPatient or patient’s legal representative able to sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient and/or legal guardian must sign informed consent for BMTXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatient or legally appropriate proxy must be able to understand study instructions and sign consentXx_NEWLINE_xXPART 2 GROUP 1 INCLUSION CRITERIA: All subjects or a parent/guardian must sign written informed consentXx_NEWLINE_xXPART 2 GROUP 2A INCLUSION CRITERIA: All subjects or a parent/guardian must sign written informed consentXx_NEWLINE_xXPART 2 GROUP 3 INCLUSION CRITERIA: All subjects or a parent/guardian must sign written informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatients must be willing and able to sign informed consent for themselvesXx_NEWLINE_xXPatients must be able to understand and sign an informed consent formXx_NEWLINE_xXPatients must be willing to sign the protocol-specific written informed consentXx_NEWLINE_xXRefusal to sign the informed consentXx_NEWLINE_xXRefusal to sign the informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXAble to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAbility for patient (and if applicable parent or legal guardian) to understand and the willingness to sign a written informed consent document, or for a parent or legal guardian to give assent for those cases where a very young patient is unable to understand or sign the consentXx_NEWLINE_xXAble to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAble to understand informed consentXx_NEWLINE_xXPatients must be willing and able to understand the informed consent documentXx_NEWLINE_xXRefusal to sign informed consentXx_NEWLINE_xXAble to sign informed consentXx_NEWLINE_xXPatient must be able to comprehend the approved consent document and have the willingness to sign it; the patient prior to enrollment and the administration of any protocol-specific therapy must sign the consent documentXx_NEWLINE_xXAble to sign informed consentXx_NEWLINE_xXPHASE I STUDY ELIGIBILITY CRITERIA:\r\nAbility of subject to understand and the willingness to sign a written informed consent document prior to any protocol related procedures, including screening evaluationsXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXAbility to understand and willingness to sign the consent form written in English\r\n* Note: the consent form must be signed prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAll subjects must sign a written informed consentXx_NEWLINE_xXAble to understand and then sign an informed consent form (ICF) prior to initiation of any study-specific procedure and treatment.Xx_NEWLINE_xXDONOR: Able to understand and sign informed consentXx_NEWLINE_xXPatient or legally authorized representative able to sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legally authorized representatives must sign a written informed consent.Xx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent formXx_NEWLINE_xXAble to understand, and the willingness to give, informed consent for the studyXx_NEWLINE_xXPatient able to sign informed consentXx_NEWLINE_xXPatient is able to understand and is willing to sign the informed consent formXx_NEWLINE_xXPatient, legally authorized representative (LAR), or parent able to sign informed consent; able to give assent for patients age 7-17Xx_NEWLINE_xXMust sign the picture consent formXx_NEWLINE_xXAble to understand, and willing to sign a written informed consent documentXx_NEWLINE_xXPatient must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXSign an informed consent documentXx_NEWLINE_xXSign a written informed consent formXx_NEWLINE_xXDONOR: Ability to comprehend and willing to sign an informed consentXx_NEWLINE_xXThe patient is able to understand and give informed consentXx_NEWLINE_xXPatients must sign an informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient or legally authorized representative able to sign informed consentXx_NEWLINE_xXAble to understand the consent competent to signXx_NEWLINE_xXPatient or patient’s legal representative, parent(s) or guardian able to sign informed consent; patients aged 7 to < 18 to provide assentXx_NEWLINE_xXPatients (parents/guardians for those < 18) and donors must be able to sign consent formsXx_NEWLINE_xXPatients must be able to understand and sign a written informed consent document and complete study-related procedures and questionnairesXx_NEWLINE_xXPatients willing and able to sign consentXx_NEWLINE_xXPatient or legally authorized representative able to sign informed consentXx_NEWLINE_xXAble to understand and sign a written informed consent document.Xx_NEWLINE_xXPatient and/or legal guardian must be able to sign informed consent.Xx_NEWLINE_xXAbility of subject to understand, and be willing to sign informed consentXx_NEWLINE_xXInability to sign informed consent documentXx_NEWLINE_xXEach patient much be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXAll subjects must sign a written informed consentXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXThe patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelinesXx_NEWLINE_xXPatients must sign informed consent prior to study entryXx_NEWLINE_xXRefusal to sign the informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatient and/or responsible person able to understand and sign consentXx_NEWLINE_xXPatient and/or responsible person able to understand and sign consentXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXAble to understand and sign a written informed consent formXx_NEWLINE_xXPatients must be able to understand and give informed consentXx_NEWLINE_xXPatients must sign informed consentXx_NEWLINE_xXPatient must give informed consent and sign an approved consent form prior to any study procedures.Xx_NEWLINE_xXWilling and able to understand and sign the study specific Informed Consent FormXx_NEWLINE_xXPatients must be able to understand and sign the informed consentXx_NEWLINE_xXAble to read or understand and give informed consent.Xx_NEWLINE_xXPatient able to understand, sign, and date the written voluntary informed consent form at screening visit prior to any protocol-specific proceduresXx_NEWLINE_xXAble to understand and sign an Informed ConsentXx_NEWLINE_xXAble to sign informed consentXx_NEWLINE_xXThe patient, or their representative, is able to understand the study and is willing to consent to participation in the study.Xx_NEWLINE_xXAble to comprehend and willing to sign the informed consent formXx_NEWLINE_xXPatients must sign an informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXUnable to sign informed consentXx_NEWLINE_xXHave the ability to understand and sign a written informed consent form, which must be obtained prior to initiation of study proceduresXx_NEWLINE_xXSubjects must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXPart 1: be able to understand the description of the study and give written informed consentXx_NEWLINE_xXProvision to sign and date the consent formXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document; subject has signed the informed consent (ICF) prior to any screening procedures being performed and is able to comply with protocol requirementsXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study.Xx_NEWLINE_xXPatient or legally authorized representative able to sign informed consentXx_NEWLINE_xXBe able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXSubjects must understand and sign the study specific informed consentXx_NEWLINE_xXThe patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelinesXx_NEWLINE_xXBe able to understand and willing to sign an informed consent form (ICF).Xx_NEWLINE_xXParticipants must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatients must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXInformed consent: all subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXSubjects must freely sign informed consent to enroll in the studyXx_NEWLINE_xXPatient able to understand and willing to sign and date the written voluntary informed consent form (ICF) at screening visit prior to any protocol-specific proceduresXx_NEWLINE_xXAbility of subject to understand, and be willing to sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatients must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXThe patient must sign an informed consent form (ICF)Xx_NEWLINE_xXPatients must sign the informed consent documentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXParticipants must sign an approved informed consent form (ICF).Xx_NEWLINE_xXPatients must be able to understand and willing to sign an informed consentXx_NEWLINE_xXMust sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatients must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAble to comprehend and willing to sign an Informed Consent Form (ICF)Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatients must sign an informed consentXx_NEWLINE_xXPatient must be willing to sign informed consentXx_NEWLINE_xXPatients must be willing and able to sign informed consentXx_NEWLINE_xXPatients must be able to understand and sign informed consentXx_NEWLINE_xXPatients must be willing and able to sign informed consentXx_NEWLINE_xXPatient needs to be able to understand and demonstrate willingness to sign a written informed consent documentXx_NEWLINE_xXAble to understand and give informed consentXx_NEWLINE_xXUnderstand and give informed consentXx_NEWLINE_xXPatient must be able to understand and willing to sign an informed consentXx_NEWLINE_xXWilling and able to sign informed consentXx_NEWLINE_xXParticipant must be capable of understanding and complying with the protocol and willing to sign a written informed consent documentXx_NEWLINE_xXMust be willing to sign a written informed consent.Xx_NEWLINE_xXWilling and able to sign written informed consent and be able to comply with the study protocol for the duration of the studyXx_NEWLINE_xXAMKL PATIENTS: Patients must be able to understand and willing to sign a written informed consentXx_NEWLINE_xXMF PATIENTS: Patients must be able to understand and willing to sign a written informed consentXx_NEWLINE_xXAble to comprehend and willing to sign an informed consent form (ICF)Xx_NEWLINE_xXPatients must sign a written informed consent prior to entering the study.Xx_NEWLINE_xXPatients must have the ability to sign an approved informed consent form (ICF).Xx_NEWLINE_xXAble to comprehend and willing to sign informed consent formXx_NEWLINE_xXAll patients must sign an informed consent prior to enrollment.Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document\r\nindicating that they understand the purpose of and procedures required for the study, including\r\nbiomarkers, and are willing to participate in the studyXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form. A signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedure.Xx_NEWLINE_xXPatient needs to be able to understand and demonstrate willingness to sign a written informed consent documentXx_NEWLINE_xXPatients must sign an informed consent documentXx_NEWLINE_xXAble to understand and willing to sign the informed consent formXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent document.Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatients must sign an informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXUnderstand and give informed consentXx_NEWLINE_xXAble to comprehend and willing to sign the informed consent formXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXThe subject must sign and date all informed consent statements; children will sign the assent form and their guardian will sign the consent formXx_NEWLINE_xXRefusal to sign informed consentXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study, including biomarkers, and are willing to participate in the studyXx_NEWLINE_xXPatients must sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPatient or patient’s legal representative, parent(s) or guardian able to sign informed consent; age 7-18 able to provide assentXx_NEWLINE_xXPatients must sign informed consentXx_NEWLINE_xXThe patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelinesXx_NEWLINE_xXPatients able to understand and willing to sign a written informed consent documentsXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAble to understand and willing to sign a Human Research Protection Office (HRPO) approved written informed consent document (or that of legally authorized representative, if applicable)Xx_NEWLINE_xXAll patients >= 18 years must sign a written informed consent; patients < 18 years old must provide assent, and the parent or legal guardian must sign the written informed consentXx_NEWLINE_xXParticipants must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXPatients must sign informed consentXx_NEWLINE_xXPatients must be able to understand and willing to sign a written informed consent document.Xx_NEWLINE_xXFailure to sign informed consentXx_NEWLINE_xXPatients must be able to understand and willing to sign an informed consentXx_NEWLINE_xXMust be able to read, understand and sign informed consentXx_NEWLINE_xXAble to sign informed consent and to comply with the protocolXx_NEWLINE_xXWilling and able to comply with the protocol and sign informed consentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAble to understand and willing to sign informed consent form (ICF)Xx_NEWLINE_xXAble to comprehend and willing to sign an Informed Consent Form (ICF)Xx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAll patients and/or a legal guardian must sign institutionally approved written informed consent documentXx_NEWLINE_xXWilling and able to understand and sign informed consent formXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects unable to review and sign informed consent formXx_NEWLINE_xXPatients must sign an approved informed consent documentXx_NEWLINE_xXAbility of participant to sign a written informed consentXx_NEWLINE_xXPatients must be able to understand and sign informed consentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXWilling and able to sign informed consentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXPatients who are not able to sign inform consentXx_NEWLINE_xXSubjects or their guardians must be able to understand and be willing to sign the written informed consent form. A signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedure.Xx_NEWLINE_xXAble to understand and willing to sign written informed consent documentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXPRE-REGISTRATION INCLUSION CRITERIA: Patient (or legally authorized representative) must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAll patients must sign informed consentXx_NEWLINE_xXEach patients must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXPatient refuses to sign informed consentXx_NEWLINE_xXPatient (or legally authorized representative) must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXable understand and give written informed consent and comply with the study protocol.Xx_NEWLINE_xXAble to understand and to sign a written consent documentXx_NEWLINE_xXPatient must be willing and able to sign the informed consent formXx_NEWLINE_xXPatient or patient’s legal representative, parent(s) or guardian able to sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXDONOR: Donors must be able to understand and sign informed consentXx_NEWLINE_xXPatients must sign the informed consent form before registrationXx_NEWLINE_xXPatient or patient’s legal representative, parent(s) or guardian able to sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign an informed consent (or have a legal representative who is able to do so)Xx_NEWLINE_xXPatient must sign the informed consent documentXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXMust be able to understand and sign the informed consent documentXx_NEWLINE_xXPatients must sign an informed consentXx_NEWLINE_xXSubject must understand and sign the study specific informed consentXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXWritten informed consent provided before any study-specific procedures are initiated. Subject must be able to understand and be willing to sign a written informed consent form.Xx_NEWLINE_xXPatient refuses to sign informed consentXx_NEWLINE_xXAble to understand and sign the Informed Consent documentXx_NEWLINE_xXMust sign an informed consent form.Xx_NEWLINE_xXBe able to understand and sign informed consentXx_NEWLINE_xXWilling and able to sign informed consentXx_NEWLINE_xXThe patient or legal guardian must be able to comprehend the informed consent form and sign prior to patient enrollmentXx_NEWLINE_xXPatients must sign informed consent prior to study entryXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXAble to comprehend and willing to sign the written informed consent formXx_NEWLINE_xXPatients must sign written informed consentXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXAble to understand and sign informed consentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to sign an informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient or patient’s legal representative, able to sign informed consentXx_NEWLINE_xXPatients must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAll patients must be able to comprehend and sign informed consentXx_NEWLINE_xXTREATMENT: Patients must be willing to sign the standard informed consentXx_NEWLINE_xXPatients or their legal representative must be able to read, understand and sign an informed consent form (ICF)Xx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXRECURRENT/ PROGRESSIVE DIPG (STRATUM 1): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelinesXx_NEWLINE_xXNON-PROGRESSED DIPG (STRATUM 2): The patient or parent/guardian is able to understand the consent and is willing to sign a written informed consent document according to institutional guidelinesXx_NEWLINE_xXAble to understand and willing to sign the informed consent formXx_NEWLINE_xXWilling and able to sign the informed consent and to comply with the protocol for the duration of the study.Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAbility to understand and sign informed consent form (ICF) and comply with treatment protocolXx_NEWLINE_xXWillingness to sign informed consent by patient or patient’s legal representativeXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXPatient must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign a consent formXx_NEWLINE_xXPatients must sign an informed consent formXx_NEWLINE_xXPatient able to understand and willing to sign and date the written voluntary informed consent form (ICF) at screening visit prior to any protocol-specific proceduresXx_NEWLINE_xXHave the ability to understand and sign a written informed consent form, which must be obtained prior to initiation of study proceduresXx_NEWLINE_xXMust sign an approved informed consentXx_NEWLINE_xXAble to understand and willing to sign the informed consent formXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatient or a legally authorized representative of a patient must be able and willing to sign informed consent document that has been approved by an IRBXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXAll patients must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXMust be able to read and understand informed consentXx_NEWLINE_xXAdults must be able to understand and sign the informed consent documentXx_NEWLINE_xXPatient or legally authorized representative able to sign an informed consent formXx_NEWLINE_xXPatient or legally authorized representative able to sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAble to understand and sign an informed consent (or have a legal representative who is able to do so)Xx_NEWLINE_xXAll patients must sign an informed consent prior to enrollmentXx_NEWLINE_xXAble to sign informed consent and to comply with the protocolXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXPatients must be able to read, understand and sign informed consentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatients of their legal representatives must be able to understand and sign an informed consent formXx_NEWLINE_xXDonor must be able to understand and willing to sign an IRB approved written informed consent document. Recipient Inclusion CriteriaXx_NEWLINE_xXRecipient must be able to understand and willing to sign an IRB approved written informed consent document.Xx_NEWLINE_xXAble to understand and willing to sign an informed consent form (ICF) prior to initiation of any study-specific procedure and treatmentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXRefusal to sign informed consentXx_NEWLINE_xXMust sign an Informed Consent Form (ICF)Xx_NEWLINE_xXAble to sign informed consent and to comply with the protocolXx_NEWLINE_xXPatients must be capable and willing to sign informed consentXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study, including biomarkers, and are willing to participate in the studyXx_NEWLINE_xXPatients must be willing to sign an informed consentXx_NEWLINE_xXAble to understand and sign the Informed Consent DocumentXx_NEWLINE_xXAble to understand and sign the informed consent documentXx_NEWLINE_xXPatients or guardian able to sign informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consent (patient assent is also recommended when applicable according to each institution’s policy)Xx_NEWLINE_xXBoth parties are required to sign an informed consentXx_NEWLINE_xXUnwilling to sign an informed consentXx_NEWLINE_xXEach patient must be willing to participate as a research subject and must sign an informed consent formXx_NEWLINE_xXPatients must sign written informed consentXx_NEWLINE_xXSign (or their legally-acceptable representatives must sign) an informed consent document indicating that they understand the purpose of and procedures required for the study, including biomarkers, and are willing to participate in the studyXx_NEWLINE_xXThe patient must be able to understand the study regimen, its requirements, risks, and discomforts, and is able and willing to sign an informed consent formXx_NEWLINE_xXSubject is able to read, understand, and sign a written Informed Consent to participate in the study.Xx_NEWLINE_xXPatient understands the study regimen, its requirements, risks, and discomforts, and is able and willing to sign an informed consent formXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXPatient able to understand and the willingness to sign a written informed consentXx_NEWLINE_xXAble to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXBoth patient and caregiver willing to give and sign informed consentXx_NEWLINE_xXAble to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatients must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirementsXx_NEWLINE_xXPotential participant/guardian is willing to sign informed consentXx_NEWLINE_xXPatient and/or parents/guardians as appropriate must sign an informed consent, be mentally responsible, able to understand and willing to sign a written informed consentXx_NEWLINE_xXMust understand and read English, sign a written informed consent, and follow protocol requirementsXx_NEWLINE_xXAble and willing to sign protocol consent formXx_NEWLINE_xXIndividual is willing to sign written informed consentXx_NEWLINE_xXPatients must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirements.Xx_NEWLINE_xXMust understand and read English, sign a written informed consent, and follow protocol requirementsXx_NEWLINE_xXAble to understand and sign the informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAble and willing to sign informed consent/assentXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXWilling to sign consentXx_NEWLINE_xXAble to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects who are able to understand and sign an informed consent documentXx_NEWLINE_xXPatient understands the study regimen, its requirements, risks, and discomforts, and is able and willing to sign an informed consent formXx_NEWLINE_xXAll subjects must be able to comprehend and sign a written informed consent documentXx_NEWLINE_xXSubjects must be able to understand and be willing to sign the written informed consent form; a signed informed consent form must be appropriately obtained prior to the conduct of any trial-specific procedureXx_NEWLINE_xXPatients must sign an informed consentXx_NEWLINE_xXEach subject must sign an informed consent form indicating that he or she understand the purpose of and procedures required for the study and are willing to participateXx_NEWLINE_xXThe patient must sign consent for study participationXx_NEWLINE_xXParticipants must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXParticipants must be able to understand and be willing to sign a written informed consent documentXx_NEWLINE_xXAble to sign informed consentXx_NEWLINE_xXInability to sign an informed consent form prior to registration on studyXx_NEWLINE_xXCapacity to understand and sign the study informed consent formXx_NEWLINE_xXSubjects must sign informed consentXx_NEWLINE_xXBe able to understand the description of the study and give written informed consentXx_NEWLINE_xXAble to understand and sign the informed consentXx_NEWLINE_xXPatients refusing to sign informed written consent for participation in researchXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consent (patient assent is also recommended when applicable according to each institution’s policy)Xx_NEWLINE_xXAble to understand and sign consentXx_NEWLINE_xXAll patients must sign a written informed consentXx_NEWLINE_xXWilling to sign informed consentXx_NEWLINE_xXPatients must be able to sign informed consentXx_NEWLINE_xXPatients must have the ability to understand English, sign a written informed consent document, and be willing to follow protocol requirementsXx_NEWLINE_xXWilling and able to read, understand and sign an informed consent form (ICF)Xx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXThe patient understands the study requirements and is willing and able to sign an informed consent documentXx_NEWLINE_xXWilling and able to understand and sign consent formXx_NEWLINE_xXSign a written informed consent documentXx_NEWLINE_xXWillingness to sign informed consent and comply with all protocol requirementsXx_NEWLINE_xXAll patients and/or their parents or legal guardians must sign a written informed consentXx_NEWLINE_xXAdult patients must be able to understand and sign a written informed consent. For minor patients, the parent/legal guardian or representative must be able to understand and sign a written informed consent. Assent, when appropriate, will be obtained according to institutional guidelines.Xx_NEWLINE_xXPatient or parent/legal guardian or representative lacks the full mental capacity to understand and sign a written informed consent.Xx_NEWLINE_xXParticipants must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatients sign the informed consentXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document; a legally authorized representative (LAR) may sign informed consent for persons who do not have the capacity to legally consent to take part in the studyXx_NEWLINE_xXAbility to understand and the willingness to sign a written informed consent document; patient must sign the informed consent (ICF) prior to any screening procedures being performed and is able to comply with protocol requirementsXx_NEWLINE_xXPatients who are able to understand and give consent to participating in the studyXx_NEWLINE_xXAbility to comprehend and sign informed consentXx_NEWLINE_xXAbility to sign informed consentXx_NEWLINE_xXPatients must sign an informed consent, and be mentally responsibleXx_NEWLINE_xXPatient is able to understand and give consent to participation in the study.Xx_NEWLINE_xXProvision to sign and date the consent formXx_NEWLINE_xXPatient is able to sign a study specific informed consent formXx_NEWLINE_xXWilling and able to sign consent form.Xx_NEWLINE_xXSign informed consentXx_NEWLINE_xXAbility to sign an informed consentXx_NEWLINE_xXSubjects who refuse to give and/or sign the informed consentXx_NEWLINE_xXPatient must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatient or legally authorized representative must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatients who agree to sign an informed consent to undergo MBIXx_NEWLINE_xXAdults with a suspected or confirmed lymphoma diagnosis and:\r\n* Who will undergo clinically indicated procedure potentially allowing for excess or discarded clinical specimens\r\n* Who must be able to understand and sign an informed consentXx_NEWLINE_xXPatients must sign an informed consent form for studyXx_NEWLINE_xXUnderstands the trial and procedure and is willing and able to sign the informed consent formXx_NEWLINE_xXRefusal to sign the informed consentXx_NEWLINE_xXPatient understands the study regimen, its requirements, risks, and discomforts, and is able and willing to sign an informed consent formXx_NEWLINE_xXAIMS 1 AND 2: Participants must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAIM 3: Participants must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatient or legally authorized representative must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatient or legally authorized representative must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXSubjects must be willing and able to understand and sign informed consentXx_NEWLINE_xXAbility to sign informed consentXx_NEWLINE_xXSubject must be willing and able (in the opinion of the investigator) to understand the informed consent formXx_NEWLINE_xXIs able to agree to and sign informed consent and to comply with the protocolXx_NEWLINE_xXSubjects must be able to understand and willing to sign a written informed consent formXx_NEWLINE_xXAble to understand and willing to sign a written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatient must sign informed consent to participate in the studyXx_NEWLINE_xXThe patient does not sign the informed consentXx_NEWLINE_xXPatient (or legally authorized representative) must be able to understand and willing to sign a written informed consent documentXx_NEWLINE_xXPatients must be able to understand and willing to sign an informed consentXx_NEWLINE_xXPatients must sign an informed consent documentXx_NEWLINE_xXMust be able to understand and sign a written informed consent documentXx_NEWLINE_xXPatients must be able to understand and willing to sign an informed consentXx_NEWLINE_xXAble to understand and sign an informed consent document (or has a legal representative who is able to do so)Xx_NEWLINE_xXSurgeon: Able to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXNurse: Able to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXAble to understand and willing to sign an IRB-approved written informed consent documentXx_NEWLINE_xXPatients must be able to understand and be willing to sign a written informed consent document to participateXx_NEWLINE_xXPatients must sign an informed consentXx_NEWLINE_xXPatients who are able to understand the investigational nature of this study and agree to sign a written informed consent documentXx_NEWLINE_xXSign an approved informed consent form for this study.Xx_NEWLINE_xXParticipant must be able to understand and give consent to participate in the studyXx_NEWLINE_xX