Women who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXWoman who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXCurrently pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeeding are excluded from the studyXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeeding (unless the patient is willing to interrupt breastfeeding during study treatment administration and then resume 6 months after study discontinuation); women of childbearing potential must not consider getting pregnant during the studyXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding, or intending to become pregnant during the studyXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPatients may not be pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant (positive urine test) or breastfeedingXx_NEWLINE_xXIs a female subject who is pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant women or women who are breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding female patientsXx_NEWLINE_xXPregnant or breastfeeding women will be excluded from participation in this trialXx_NEWLINE_xXPatients who are breastfeeding, pregnant, or planning to become pregnant from the time of informed consent until 6 months after the final study dose is administeredXx_NEWLINE_xXAre pregnant or breastfeeding.Xx_NEWLINE_xXIs not pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXPregnant or breastfeeding female.Xx_NEWLINE_xXPatients must not be pregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXFemales only: pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXIf female, is pregnant, breastfeeding, or planning to become pregnant.Xx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXCurrently pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women, or intending to become pregnant during the studyXx_NEWLINE_xXSubject is pregnant or breastfeeding.Xx_NEWLINE_xXBreastfeeding or pregnant.Xx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding, or intending to become pregnant during the studyXx_NEWLINE_xXIf female, is pregnant, breastfeeding, or planning to become pregnant.Xx_NEWLINE_xXFemale subject who is pregnant or breastfeeding.Xx_NEWLINE_xXIf female, subject is pregnant and/or breastfeeding.Xx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemale patients may not be pregnant or breastfeedingXx_NEWLINE_xXSubjects that are pregnant or breastfeeding an infant.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding and who are unwilling to stop breastfeeding prior to study entryXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXCurrently pregnant or breastfeedingXx_NEWLINE_xXWomen of childbearing potential who are pregnant or breastfeedingXx_NEWLINE_xXPatients that are pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding, or intending to become pregnant during the study or within 140 days after the last dose of BTRC4017AXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXParticipants who are women must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXInability or refusal to practice effective contraception during therapy or the presence of pregnancy or active breastfeeding; pregnant or breastfeeding women will be excluded from participation in this trialXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnancy, breastfeeding, or intention of becoming pregnant during the studyXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemale participants who are pregnant or breastfeeding are excluded.Xx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding female patientsXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be pregnant (as above) or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding, or intending to become pregnant during the studyXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen must not be pregnant (as above) or breastfeedingXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding or planning to become pregnant within 90 days after their last anticipated dose of BCVXx_NEWLINE_xXThe participant is pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXAre females who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXWOCBP who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant, breastfeeding, or plan to become pregnant during the study durationXx_NEWLINE_xXHEALTHY SUBJECT: Not pregnant or breastfeedingXx_NEWLINE_xXFemale subjects who are pregnant, are planning on becoming pregnant, or are currently breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or actively breastfeeding womenXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXSubject is pregnant or breastfeeding.Xx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXDONOR: WOCBP: Pregnant or =< 6 months breastfeedingXx_NEWLINE_xXFemale patients who are pregnant or breastfeeding; breastfeeding should be discontinuedXx_NEWLINE_xXPregnant or breastfeeding women are excluded from this studyXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXCRITERIA FOR SCREENING: Pregnant or breastfeeding womenXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women;Xx_NEWLINE_xXSubjects who are pregnant or breastfeeding, or may become pregnant during metformin and doxycycline administrationXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXDONOR: Pregnant and/or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXSubjects who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant women and breastfeeding mothers are excludedXx_NEWLINE_xXFemales who are pregnant or are currently breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXBreastfeeding femalesXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXBreastfeeding or pregnantXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnancy, breastfeeding or possibility of becoming pregnant during the study.Xx_NEWLINE_xXIs pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXWomen of childbearing potential who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are of pregnant or breastfeedingXx_NEWLINE_xXThe patient is pregnant or is breastfeeding.Xx_NEWLINE_xXSubjects who are pregnant or breastfeeding or may become pregnant during metformin and doxycycline administrationXx_NEWLINE_xXWomen who are pregnant or breastfeeding; women who agree to stop breastfeeding would be eligibleXx_NEWLINE_xXPatients who are pregnant or breastfeeding will be excluded from the studyXx_NEWLINE_xXSubjects who are pregnant or breastfeeding are excludedXx_NEWLINE_xXPregnant or breastfeeding (female only)Xx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXDONOR: Pregnant and/or breastfeedingXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are excluded.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXIs pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemale subjects who are breastfeeding, pregnant, or plan to become pregnant during the study or within 3 months following the last dose of investigational productXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant, or who are currently breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXBreastfeeding women.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXDONOR: Pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women are excluded from this studyXx_NEWLINE_xXWomen who are pregnant or breastfeeding are excluded from the studyXx_NEWLINE_xXPregnant or breastfeeding participantsXx_NEWLINE_xXFemale subjects who are pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding, pregnant, women of childbearing potential not using contraceptionXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXADDITIONAL CRITERIA FOR STUDY CONTINUATION: Pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women are excluded from this studyXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPART 1: Pregnant or breastfeedingXx_NEWLINE_xXPART 2: Pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women are excluded from this studyXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women are excluded from this study; breastfeeding should be discontinuedXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant women are excluded from this study; breastfeeding should also be avoidedXx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are excluded from this studyXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXPregnant women are excluded from this study; breastfeeding should also be avoidedXx_NEWLINE_xXFemales who are pregnant or are currently breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXAre pregnant or breastfeeding.Xx_NEWLINE_xXPatients who are pregnant or breastfeeding are excluded from the studyXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding femaleXx_NEWLINE_xXPregnant or breastfeeding woman.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXParticipant is pregnant or is a breastfeeding femaleXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPatients who are currently pregnant or breastfeeding.Xx_NEWLINE_xXAre pregnant or breastfeedingXx_NEWLINE_xXFemales must not be pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXWOCBP: Pregnant or breastfeedingXx_NEWLINE_xXPregnant or is breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeeding.Xx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding female patients.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemale only: pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXPregnant or breastfeeding, or planning to become pregnant within 6 months after the end of treatmentXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPregnant women are excluded from this study; breastfeeding should also be avoidedXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXAre female and pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding female.Xx_NEWLINE_xXParticipants who are pregnant or breastfeedingXx_NEWLINE_xXWomen currently pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXTUMOR BIOPSY SEQUENCING: Women who are pregnant or breastfeedingXx_NEWLINE_xXTREATMENT: Women who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be pregnant (as above) or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding patients are not eligibleXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXNot breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemale subject who is pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding patients are ineligibleXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemale patient who is pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXWomen must not be pregnant or breastfeeding; breastfeeding must be discontinued or the subject is not eligible for the studyXx_NEWLINE_xXPHASE II: Women must not be pregnant or breastfeeding; breastfeeding must be discontinued or the subject is not eligible for the studyXx_NEWLINE_xXPatient must not be pregnant and/or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXThe subject is pregnant or breastfeeding.Xx_NEWLINE_xXSubjects who are pregnant or breastfeeding.Xx_NEWLINE_xXCurrently pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding; women of childbearing potential must not be considering getting pregnant during the studyXx_NEWLINE_xXFemales who are pregnant, unable to comply with birth control use to avoid becoming pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeeding.Xx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXBreastfeeding or pregnant.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are excluded from this studyXx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXParticipants who are breastfeeding, or intending to become pregnant during the studyXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXIs pregnant or breastfeeding.Xx_NEWLINE_xXBe pregnant, planning a pregnancy, or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant or breastfeeding patients;Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding woman or female who intends to become pregnant during the participation in the study.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXare pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding or pregnantXx_NEWLINE_xXFemales who are pregnant or breastfeeding as well as all females of childbearing potential who:Xx_NEWLINE_xXBreastfeeding women.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXAre pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXSubject is pregnant or breastfeeding or intends to get pregnant within 28 days of enrolling into the study.Xx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXSubject if female, is pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeeding at the time of study registrationXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXIs pregnant, breastfeeding, or planning a pregnancyXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXCurrent breastfeeding (females only)Xx_NEWLINE_xXBreastfeeding and pregnant.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXBreastfeeding or pregnantXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWOCBP who are pregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding.Xx_NEWLINE_xXBreastfeeding or pregnantXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemale subjects that are pregnant or breastfeeding are not eligibleXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXBe pregnant or breastfeeding.Xx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXWomen who are breastfeeding or pregnantXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXAre pregnant or breastfeedingXx_NEWLINE_xXA participant who is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatient is breastfeeding.Xx_NEWLINE_xXPregnant or patients who are breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding or pregnantXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXFemales who are pregnant or breastfeeding, and males and females who cannot comply with requirements to avoid fathering a child or becoming pregnantXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXIs pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding women, pregnant womenXx_NEWLINE_xXParticipant is pregnant or breastfeedingXx_NEWLINE_xXPART B: Pregnant or breastfeeding womenXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXThe patient is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or are currently breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant and/or breastfeedingXx_NEWLINE_xXBe a woman who is pregnant or breastfeedingXx_NEWLINE_xXMust not be pregnant or breastfeeding.Xx_NEWLINE_xXWomen must NOT be pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXThe participant is pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding patientsXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemale patients who are pregnant or currently breastfeedingXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXPregnant (positive ?-HCG) or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding; breastfeeding may not resume for 14 days after the last dose of pazopanibXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant, or actively breastfeeding females.Xx_NEWLINE_xXFemale patients who are breastfeeding or pregnantXx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXEXPANSION COHORT ONLY: Pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding mothersXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant or breastfeeding patientsXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant women or females who are breastfeedingXx_NEWLINE_xXCurrently pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXBreastfeeding or pregnant.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXThe participant is pregnant, breastfeeding, or planning to become pregnant or father a childXx_NEWLINE_xXBreastfeeding or pregnantXx_NEWLINE_xXFemale subjects that are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXAre pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xX16. Women who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen that are pregnant or breastfeedingXx_NEWLINE_xXSubject is currently pregnant or breastfeeding, or is planning to become pregnant during the studyXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXAre pregnant or breastfeeding.Xx_NEWLINE_xXSubject is pregnant or breastfeedingXx_NEWLINE_xXPregnant, breastfeeding, or planning to become pregnant during the study;Xx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXNot breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen must not be breastfeeding.Xx_NEWLINE_xXParticipants who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPatients may not be pregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding or pregnantXx_NEWLINE_xXThe subject is pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding women are excluded from this study; breastfeeding should be discontinuedXx_NEWLINE_xXWomen of childbearing potential who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXIs pregnant, breastfeeding, or planning a pregnancyXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXIs the subject breastfeeding?Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales of childbearing potential who are not pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeeding.Xx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXFemale subjects who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXFemales must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding, or intending to become pregnant during the studyXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXBe pregnant or breastfeedingXx_NEWLINE_xXRecipient must not be pregnant and/or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXFemales who are pregnant or are breastfeeding.Xx_NEWLINE_xXThe subject is pregnant or breastfeedingXx_NEWLINE_xXBreastfeeding or pregnant femalesXx_NEWLINE_xXFemale subjects who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant (positive total HCG) or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding (women)Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding femalesXx_NEWLINE_xXPregnant, breastfeeding or considering becoming pregnant within 6 months following the last dose of investigational product;Xx_NEWLINE_xXSubject is pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXAs per self-report participants who are pregnant or who are breastfeedingXx_NEWLINE_xXPatient is pregnant, breastfeeding, has given birth within the last 3 months or planning pregnancy within the next 12 months; if participant becomes pregnant during the course of the study, she will be removed from further participationXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are excluded from this studyXx_NEWLINE_xXNot pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are not eligible for thyroidectomy and so are excluded from this studyXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFor women: breastfeeding, pregnancy, or plan to become pregnant within 6 monthsXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding are ineligibleXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or are currently breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding;Xx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant and/or breastfeedingXx_NEWLINE_xXPatient must not be pregnant and/or breastfeedingXx_NEWLINE_xXFemale subjects who are pregnant or breastfeedingXx_NEWLINE_xXFemale subjects who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding or planning to become pregnant or breastfeed during the period of treatment and for 112 days following the last dose of sotaterceptXx_NEWLINE_xXIs pregnant or breastfeedingXx_NEWLINE_xXFemale who is pregnant or breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant (positive serum or urine ?HCG) or breastfeedingXx_NEWLINE_xXThey are not breastfeeding;Xx_NEWLINE_xXPregnant or intention to get pregnant, or breastfeeding; pregnant women are excluded from this study; women who are breastfeeding will be excludedXx_NEWLINE_xXCurrently breastfeeding.Xx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXBreastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are breastfeeding are not eligible for this study.Xx_NEWLINE_xXWomen who are breastfeeding, pregnant, or planning pregnancy within the next yearXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant, contemplating getting pregnant, or breastfeedingXx_NEWLINE_xXFor women, current pregnancy or breastfeeding or plan to become pregnant during the next 2 months.Xx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXCurrent breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXIs pregnant, intends to become pregnant during study, or is breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXBreastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXNo breastfeedingXx_NEWLINE_xXPregnant, contemplating getting pregnant, or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXmen and non-pregnant, non-breastfeeding womenXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXNot pregnant and/or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding.Xx_NEWLINE_xXPatient must NOT be breastfeeding.Xx_NEWLINE_xXPregnant women or breastfeeding\r\n* Potential subjects will be asked if they are pregnant; verbal confirmation of pregnancy will be sufficientXx_NEWLINE_xXFemale patients who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding womenXx_NEWLINE_xXNot pregnant and/or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding patientsXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXWomen must not be pregnant nor breastfeedingXx_NEWLINE_xXWomen who are breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding patientsXx_NEWLINE_xXPatient who is pregnant and/or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeedingXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding females.Xx_NEWLINE_xXIs pregnant or breastfeedingXx_NEWLINE_xXPregnant and/or breastfeeding women.Xx_NEWLINE_xXFemale patients who are pregnant or actively breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXNot pregnant, not breastfeedingXx_NEWLINE_xXYou are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding at time of consentXx_NEWLINE_xXBreastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeedingXx_NEWLINE_xXPregnant and breastfeeding women are excluded from this studyXx_NEWLINE_xXPatient is pregnant or breastfeedingXx_NEWLINE_xXPatient must not be pregnant or breastfeedingXx_NEWLINE_xXFemales who are breastfeeding or pregnant.Xx_NEWLINE_xXPatients who are pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant, intend to become pregnant within 3 months of the study period, or who are breastfeedingXx_NEWLINE_xXParticipants who are breastfeeding, pregnant or trying to become pregnantXx_NEWLINE_xXBreastfeeding, pregnant, or likely to become pregnant during the studyXx_NEWLINE_xXPregnant or breastfeedingXx_NEWLINE_xXPregnant or breastfeeding, or planning to become pregnant.Xx_NEWLINE_xXWomen who are pregnant, intend to become pregnant within 3 months of the study period, or who are breastfeedingXx_NEWLINE_xXPatients may not be pregnant or breastfeedingXx_NEWLINE_xXFor female participants: being pregnant or breastfeeding, or planning to become pregnant, by self-reportXx_NEWLINE_xXPregnancy or uninterruptible breastfeeding. Pregnancy is an absolute contraindication under this protocol. Women who are breastfeeding must be willing and able to interrupt breastfeeding during the administration of filgrastim and for two days following the final dose.Xx_NEWLINE_xXWomen must not be breastfeedingXx_NEWLINE_xXPatients who are pregnant or breastfeeding or likely to become pregnantXx_NEWLINE_xXpregnant or breastfeedingXx_NEWLINE_xXnot pregnant, breastfeeding, or planning to become pregnantXx_NEWLINE_xXWomen of childbearing potential who are pregnant or breastfeedingXx_NEWLINE_xXFemale subject who is pregnant or breastfeeding, or planning to become pregnant within 30 days after ending treatmentXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXParticipants must not be known to be pregnant or breastfeedingXx_NEWLINE_xXWomen who are pregnant or breastfeeding.Xx_NEWLINE_xXWomen of childbearing potential who are pregnant or breastfeedingXx_NEWLINE_xXFemales who are pregnant or breastfeeding.Xx_NEWLINE_xXPregnant or breastfeeding women.Xx_NEWLINE_xX