Human immunodeficiency virus (HIV) negative Immunocompromised patients (other than that related to the use of corticosteroids) including patients known to be human immunodeficiency virus (HIV) positive Patients known to be human immunodeficiency virus (HIV) positive and currently receiving retroviral therapy are not eligible; note: patients known to be HIV positive, but without clinical evidence of an immunocompromised state, are eligible for the study Patients with known human immunodeficiency virus (HIV) infection are excluded No human immunodeficiency virus (HIV) infection; patients with immune dysfunction are at a significantly higher risk of toxicities from intensive immunosuppressive therapies Patients must not be known to be human immunodeficiency virus (HIV)-positive PROCUREMENT: Patients with active human immunodeficiency virus (HIV) positive at time of procurement (can be pending at the time of blood draw) Patients with a known active infection, e.g., hepatitis B virus or hepatitis C virus; human immunodeficiency virus (HIV)-positive patients who are otherwise well and who do not have evidence of significant immune compromise are eligible Patients with known chronic human immunodeficiency virus (HIV), hepatitis B or hepatitis C infections should be excluded Human immunodeficiency virus (HIV)-positive patients Patients that are known to be positive for human immunodeficiency virus (HIV) are not eligible; note: inclusion of HIV positive patients will be considered at a later date Patients with chronic human immunodeficiency virus (HIV), hepatitis B or hepatitis C infections should be excluded Known human immunodeficiency virus (HIV) infected patients (HIV testing will not be performed as a part of screening) on combination antiretroviral therapy are eligible for inclusion; the use of zidovudine is not allowed Patients with known human immunodeficiency virus (HIV) infection Patients must not have known human immunodeficiency virus (HIV) infection or active hepatitis B or C infections Patients with known human immunodeficiency virus infection are not to be enrolled in the study Patients with known human immunodeficiency virus (HIV) or hepatitis B or C are excluded Patients known to be positive for human immunodeficiency virus (HIV) are not eligible Negative serology (antibody test) for the following infectious diseases:* Human immunodeficiency virus (HIV) type 1 and 2* Human T-cell leukemia virus (HTLV) type 1 and 2 (mandatory in United States [US] but optional in Canada and Europe)* Hepatitis B surface antigen* Hepatitis C antibody Individuals who are known to be human immunodeficiency virus (HIV) infected are eligible (note: HIV testing is not required for entry into the study) Human immunodeficiency virus (HIV) positive patients will be excluded Patients with human immunodeficiency virus (HIV) infection are ineligible Patients with human immunodeficiency virus (HIV) are excluded Known human immunodeficiency virus (HIV)-positive individuals are ineligible Known human immunodeficiency virus (HIV)-positive individuals are ineligible Immunocompromised patients (other than that related to the primary oncologic diagnosis or to the use of corticosteroids) including patients known to be human immunodeficiency virus (HIV) positive are not eligible History of human immunodeficiency virus (HIV) infection Patients should be excluded if they have known history of testing positive for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome (AIDS) Patients must not have a known history of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C infection that is untreated and/or with a detectable viral load Patients must not have known history of testing positive for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome (AIDS) Known history of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C infection or known history of tuberculosis Human immunodeficiency virus (HIV) infection No known evidence of human immunodeficiency virus (HIV) infection Any evidence of severe or uncontrolled systemic disease, active infection, active bleeding diatheses, or renal transplant, including any patient known to have hepatitis B, hepatitis C, or human immunodeficiency virus (HIV) will be excluded; patients with HIV who have adequate CD4 count, not requiring antiretroviral medication, may be enrolled Other viral infections* Known to have acute or chronic active hepatitis B or hepatitis C infection* Known to have human immunodeficiency virus (HIV) infection* Prior therapy with viral-based tumor vaccine* Received live vaccine within 28 days prior to enrollment Patients with known human immunodeficiency virus (HIV), hepatitis B or C infections; testing to prove negative status is not required for enrollment unless it is deemed necessary for usual medical care of the patient Patients must not have known history of hepatitis B, hepatitis C, human immunodeficiency virus (HIV); the use of physiologic doses of corticosteroids may be approved after consultation with the study chair Other viral infections:* Known to have acute or chronic active hepatitis B or hepatitis C infection* Known to have human immunodeficiency virus (HIV) infection* Prior therapy with viral-based tumor vaccine* Received live vaccine within 28 days prior to enrollment Patients with other viral infections are ineligible:* Known to have acute or chronic active hepatitis B or hepatitis C infection* Known to have human immunodeficiency virus (HIV) infection* Prior therapy with viral-based tumor vaccine* Received live vaccine within 28 days prior to enrollment Patients with a known history of human immunodeficiency virus (HIV) must have CD4 count >= institutional lower limit of normal within 28 days prior to registration Patient who are known to be serologically positive for human immunodeficiency virus (HIV)