Patients must provide study specific informed consent prior to study entry, including consent for mandatory tissue submission for EGFR and for oropharyngeal patients, HPV analyses Patient must provide study-specific informed consent prior to study entry Patient must be able to provide study-specific informed consent prior to study entry Signed study-specific informed consent Patient must be able to provide study specific informed consent prior to study entry Patient must provide study specific informed consent prior to study entry Signed study-specific informed consent prior to registration Patient must be able to provide study-specific informed consent prior to study entry The ability to provide written informed consent prior to study specific screening procedures, with the understanding that the patient has the right to withdraw from the study at any time Patients must provide study specific informed consent prior to study entry, including consent for mandatory tissue submission for central review Patient must provide study specific informed consent prior to study entry, including consent for mandatory tissue submission for epidermal growth factor receptor (EGFR) analysis and for oropharyngeal cancer patients, human papilloma virus (HPV) analysis Patient must provide study specific informed consent prior to study entry, including consent for mandatory screening of tissue Patient must provide study-specific informed consent prior to study entry Patient must provide study specific informed consent prior to study entry, including the mandatory pre-treatment plasma EBV DNA assay Provision of informed consent prior to any study specific procedures Patient must provide study specific informed consent prior to study entry Patient must provide study specific informed consent prior to study entry Patients must provide study-specific informed consent prior to step 1 registration The patient or a legally authorized representative must provide study-specific informed consent prior to study entry The patient or a legally authorized representative must provide study-specific informed consent prior to study entry Patients must provide study-specific informed consent prior to registration Patient must have provided study specific informed consent prior to study entry Patient must provide study specific informed consent prior to study entry Patients must sign a study-specific informed consent prior to study entry The patient must provide study-specific informed consent prior to study entry The patient or a legally authorized representative must provide study-specific informed consent prior to study entry, including consent for mandatory tumor tissue, serum, and blood submission for immune correlatives (all patients) and p16 analysis (oropharyngeal cases only) The patient or a legally authorized representative must provide study-specific informed consent prior to study entry. The patient or a legally authorized representative must provide study-specific informed consent prior to step 1 registration The patient or a legally authorized representative must provide study-specific informed consent prior to study entry The patient or a legally authorized representative must provide study-specific informed consent prior to step 1 registration The patient or a legally authorized representative must provide study-specific informed consent prior to study registration The patient or a legally authorized representative must provide study-specific informed consent prior to study entry