Participants must, in the opinion of the investigator, be capable of complying with the protocol Participants must in the opinion of the investigator be capable of complying with this protocol Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Participants must, in the opinion of the Investigator, be capable of complying with the requirements of this protocol including self-administration of study treatment Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Participants must, in the opinion of the investigator, be capable of complying with the requirements of this protocol Patients who, in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study are not eligible Participants must, in the opinion of the investigator, be capable of complying with the protocol Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who, in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible Patients who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study are not eligible