AST =< 2 x upper limit of normal TREATMENT: Creatinine =< 2 x upper limit of normal for age Creatinine =< 1.5 x upper limit of normal (ULN) Creatinine =< 1.5 x upper limit of normal (ULN) Creatinine =< twice upper limit institutional normal Creatinine < 1.5 times institutional upper limit of normal, within 21 days prior to study entry Creatinine < 1.5 institutional upper limit of normal OR Serum creatinine of =< 1.5 X the upper limit of normal TREATMENT: AST (SGOT)/ALT (SGPT) =< 3 x institutional upper limit of normal Creatinine =< 1.5 x upper limit of normal (ULN) within 14 days prior to study registration Serum creatinine > 2 times the upper limit of normal Creatinine =< institutional upper limit of normal OR Creatinine =< 1.5 x institutional/laboratory upper limit of normal (ULN) AST/ALT =< 3 x upper limit of normal (ULN) Creatinine (Cr) < 1.5 upper limit of normal (ULN) Creatinine =< 1.5 x institutional upper limit of normal Creatine phosphokinase =< institutional upper limit of normal Serum creatinine =< 1.5 x upper limit of normal (ULN) Creatinine =< 1.5 x upper limit of normal (ULN) Serum creatinine of =< 1.5 x the upper limit of normal Creatinine =< 1.5 x upper limit of normal (ULN) Note: ULN is institutional or laboratory upper limit of normal Creatinine =< 1.5 x upper limit of normal (ULN) or Within 14 days prior to registration: Creatinine =< 1.5 x institutional upper limit of normal (ULN) Creatinine =< 1.5 x upper limit of normal (ULN) or AST =< 8 x upper limit of normal (ULN)