Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter (mcL) Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 2,500/microliter Leukocytes >= 3,000/microliter Leukocytes >= 2,500/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Leukocytes >= 3,000/microliter Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients residing in prison Patients must be either: Patients must: Patients must =< 25 ALL PATIENTS Patients with prolactinomas Patients with T4 disease Patients with N3 disease Patients must either: Patients must have: Patients who are in-patients. Splenectomized patients Patients must have either: Patients with MEN 2b (since these patients may have megacolon) Patients who either ALL PATIENTS: Patients may be: Patients must have: Patients who have: Patients who: Patients with: Patients must have: Patients must have: For all patients: ALL PATIENTS: Patients with: All patients must: Patients who either Patients with galactosemia PATIENTS Patients who are delirious PATIENTS: Find conversations around religion or spirituality emotionally upsetting PATIENTS: PATIENTS PATIENTS WITH BRONJ: PATIENTS WITHOUT BRONJ: Patients PATIENTS: Active breast-feeding is also not allowed on study enrollment Interest in future fertility Interest in future fertility interest in future fertility; Are interested in future fertility, Interest in future fertility Women desiring future fertility except in the screening arm of the trial Unmanageable claustrophobia ECOG < 2 ECOG of 0-1 at screen ECOG ? 2 ECOG ? 1 Patient with ECOG ? 2 ECOG 0-2 ECOG 0 or 1 ECOG 0 or 1 ECOG 0-2 PART II: ECOG 0-1 ECOG 3 - 4 ECOG 0 or 1 ECOG 0 or 1 ECOG of 0 or 1 ECOG 0-2 ECOG ?2. Patient with ECOG ? 2 ECOG 0,1 ECOG 3 or 4 ECOG ? 1 ECOG of 0 to 1 ECOG ?2. ECOG 0 or 1 ECOG ? 2 ECOG 0 or 1 ECOG 0 to 2 ECOG=2 or better ECOG of 0 or 1 ECOG of 0 or 1. ECOG ? 2. ECOG 0-1 ECOG 0 or 1 ECOG ? 2 ECOG 0, 1 or 2 ECOG of 0 or 1 ECOG > 2 ECOG 0 or 1 at enrolment. ECOG 0, 1, or 2 Inability or unwillingness to swallow pills Inability or unwillingness to swallow pills Inability or unwillingness to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability or unwillingness to swallow whole pills Inability to swallow pills; Inability to swallow pills Inability to swallow pills Inability or unwillingness to swallow pills Inability or unwillingness to swallow pills. Inability or unwillingness to swallow pills. Inability or unwillingness to swallow pills Inability to swallow pills Inability or unwillingness to swallow pills Inability or unwillingness to swallow pills Inability to swallow pills Inability or unwillingness to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability to swallow pills Inability or unwillingness to swallow pills History of sarcoidosis syndrome History of sarcoidosis syndrome History of sarcoidosis History of sarcoidosis syndrome History of sarcoidosis syndrome History of sarcoidosis syndrome History of sarcoidosis syndrome History of sarcoidosis syndrome. History of sarcoidosis syndrome History of sarcoidosis History of sarcoidosis syndrome Bladder post-void residual volume (PVR) of >750 mL. Bladder post-void residual volume of >500 mL. Post Void Residual (PVR) bladder volume > 250 mL Bladder Post-Void Residual Volume (PVR) of > 250-mL. Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year Concomitant illness associated with a likely survival of < 1 year