Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal (LLN), within 14 days before the first dose of cabozantinib
Serum phosphorus >= lower limit of normal (LLN) within 7 days before the first dose of cabozantinib
Calcium >= LLN within 7 days before the first dose of cabozantinib
Magnesium >= LLN within 7 days before the first dose of cabozantinib
Potassium >= LLN within 7 days before the first dose of cabozantinib
Obtained within 28 days prior to the first dose of cabozantinib: serum phosphorus >= 2.5 mg/dl.
Within 4 days prior to the first dose of cabozantinib: Serum phosphorus, calcium, potassium >= lower limit of normal (LLN)
Within 7 days before the first dose of cabozantinib: Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal (LLN)
Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal (LLN)
Phosphorus >= LLN; NOTE: Supplementation may be given before the first dose of study medication
Serum phosphorus >= lower limit of normal (LLN)
Serum phosphorus >= 2.3 and < 4.8 mg/dL
Serum phosphorus within normal institutional limits
Phosphorus WNL
Demonstrate adequate organ function as defined in protocol, AND normal (WNL of local lab range) serum correct calcium, and phosphorus levels.
Phosphorus =< institutional upper limit of normal
Within 7 days before the first dose of study treatment: Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal (LLN)
Serum calcium & phosphorus within normal institutional limits
Use of medications that increase serum levels of phosphorus and/or calcium
Inorganic phosphorus outside of normal limits
Serum phosphorus >= lower limit of normal (LLN)
Serum phosphorus >= lower limit of normal (LLN)
Phosphorus < LLN
Normal phosphorus (can be on oral supplementation)
Phosphorus >= 2.3 mg/dL
RENAL COHORT: Laboratory values as follows within 4 days before the first dose of daratumumab: serum phosphorus ? lower limit of normal (LLN)
Phosphorus >= LLN =< 14 days prior to registration\r\n* NOTE: Supplementation may be given before the first dose of study medication
Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal (LLN)
Serum phosphorus >= lower limit of normal
Phosphorus above lower limit normal range for the institution; supplementation may be given before the first dose of study medication
Serum phosphorus >= lower limit of normal (LLN)
Serum phosphorus, calcium and potassium >= lower limit of normal (LLN)
Obtained =< 7 days prior to registration: Phosphorus WNL
Serum phosphorus >= LLN
Serum phosphorus >= lower limit of normal (LLN)
Serum phosphorus >= lower limits of normal (LLN)
Serum phosphorus >= lower limit of normal (LLN)
Serum potassium, magnesium and phosphorus >= lower limit of normal (LLN) and =< 1.2 x ULN
Serum phosphorus, magnesium, calcium and potassium >= lower limit of normal (LLN)
Serum phosphorus >= lower limit of normal (LLN) (if below LLN, for asymptomatic patients replacement may be initiated if clinically indicated without delaying the start of study treatment)
Serum phosphorus >= LLN
Serum phosphorus > 2.5; electrolyte repletion is allowed to reach these values
Use of medications that increase serum levels of phosphorus and/or calcium
Inorganic phosphorus outside of normal limits
Sodium, potassium, and phosphorus levels no worse than grade 1
Serum phosphorus >= LLN
Serum phosphorus calcium, magnesium and potassium >= lower limit of normal (LLN)
Serum phosphorus, magnesium, and potassium >= lower limit of normal (LLN) after adequate supplementation if necessary
Phosphorus >= institutional lower limit of normal (repletion allowed)
Normal serum electrolytes, magnesium and phosphorus on the day of therapy; correction of abnormalities is permitted
Calcium phosphorus product less than 4.0mmol2/L2.
Inorganic phosphorus =< ULN
Phosphorus less than 4.0 times below or above the upper or lower limit range
Within 2 weeks prior to registration: Serum calcium (absolute or albumin corrected), magnesium and potassium >= lower limit of normal (LLN)\r\n* NOTE: serum calcium, magnesium and potassium can be replaced if values are below LLN
Magnesium >= LLN
Sodium >= LLN
Calcium >= LLN
Magnesium >= LLN
Potassium >= LLN
Serum potassium and magnesium greater than the institutional lower limit of normal (LLN).
Serum potassium and magnesium greater than the institutional LLN.
Serum potassium >= LLN
Serum sodium >= LLN
Serum sodium >= LLN
Serum B12 and folate levels >= lower limit of normal (LLN) for the laboratory\r\n* Note: Patients may begin B12 and folic acid supplementation and be reconsidered for participation in the study when levels are >= LLN for the laboratory
Serum calcium >= LLN
Serum magnesium >= LLN
Serum potassium >= LLN
Fibrinogen >0.5 LLN
Serum calcium >= LLN
Serum magnesium >= LLN
Serum potassium >= LLN
Potassium < LLN
Serum sodium >= LLN
Abnormal LVEF (< LLN for the institution for a patient of that age) on echocardiogram
RENAL COHORT: Laboratory values as follows within 4 days before the first dose of daratumumab: magnesium ? LLN
Magnesium >= LLN =< 14 days prior to registration\r\n* NOTE: Supplementation may be given before the first dose of study medication
Sodium >= LLN =< 14 days prior to registration\r\n* NOTE: Supplementation may be given before the first dose of study medication
LVEF < LLN on screening exam
LVEF below institutional LLN or below 50%, whichever is lower
Serum potassium >= lower limit of normal (LLN) and serum magnesium >= LLN (electrolyte levels may be achieved with repletion or other supportive medications like potassium sparing diuretics)
Fibrinogen ?0.75 LLN
Calcium >= LLN
Magnesium >= LLN
Potassium >= LLN
K+ or Mg+ < LLN.
Serum magnesium ? Institutional LLN
Serum magnesium >= LLN
Calcium >= LLN
Magnesium >= LLN
Potassium >= LLN
Serum magnesium >= LLN
Patient must have the following laboratory values or have the following laboratory values corrected with supplements to be within normal limits at screening:\r\n* Potassium >= lower limit of normal (LLN)\r\n* Magnesium >= LLN\r\n* Phosphorus >= LLN\r\n* Total calcium (corrected for serum albumin) >= LLN
Serum calcium >= LLN (if below LLN, for asymptomatic patients replacement may be initiated if clinically indicated without delaying the start of study treatment)
Serum magnesium >= LLN (if below LLN, for asymptomatic patients replacement may be initiated if clinically indicated without delaying the start of study treatment)
Serum potassium >= LLN (if below LLN, for asymptomatic patients replacement may be initiated if clinically indicated without delaying the start of study treatment)
Serum magnesium >= LLN
LVEF < LLN for the institution
Serum magnesium >= LLN
Serum phosphorous >= LLN
Serum magnesium >= LLN
Serum magnesium greater than the LLN and < 3.0 mg/dL or 1.23 mmol/L
Serum sodium, potassium, magnesium, phosphate, and calcium > lower limit of normal (LLN)
Serum potassium and serum magnesium ? institutional lower limit of normal (LLN).
Magnesium >= 1.4 mg/dL or at/above the lower limit of normal for the performing laboratory
Magnesium above the institutional lower limit of normal (supplementation to meet this is allowed)
Magnesium >= lower limit of normal
Potassium, magnesium, phosphate must be corrected to at least lower limit of laboratory normal prior to start of treatment
Serum calcium and magnesium above the institutional lower limit of normal, within 14 days of registration and within 7 days of the start of treatment
Magnesium > 1.2 and < 2.5 mg/dL.
Magnesium >= 0.9 mg/dL
Magnesium >= the lower limit of normal
Magnesium level between 1.8-2.9 mg
Magnesium (triplet combination only) >= 1.8 mg/dL
Magnesium >= the lower limit of normal
Magnesium >= lower limit of normal (LLN) and =< ULN
Magnesium >= lower limit of normal
Magnesium above lower limit normal range for the institution; supplementation may be given before the first dose of study medication
Magnesium >= the lower limit of normal
Serum potassium and magnesium levels above the lower limit of normal
Magnesium 1.6 – 2.6 mg/dL
Serum magnesium >= the institutional lower limit of normal (supplementation of electrolytes prior to screening is allowed)
Magnesium >= the lower limit of normal
Magnesium >= the lower limit of normal for the institution
Magnesium at or above lower limit of normal (correction with supplements is fine as long as the resultant level is at or above the lower limit of normal)
Magnesium
Magnesium (1.2 - ULN)
Magnesium levels >= lower limit of normal
Magnesium level >= lower limit of normal
Magnesium >= 1.2mg/dL or 0.5 mmol/L
Magnesium >= the lower limit of normal
Magnesium less than 0.9 milligram per deciliter (mg/dL)
Because of the potential risk of QTc changes, serum magnesium and phosphorous levels must be >= the institutional lower limit of normal
Magnesium >= the lower limit of normal
Magnesium >= lower limit of normal (=< 48 hours prior to registration)
Magnesium >= the lower limit of normal
Magnesium ? lower limit of normal (LLN)
Magnesium >= 1.6 mg/dL
Magnesium >= the lower limit of normal
Serum magnesium >= 1.8 mg/dL
The following laboratory values must be greater than the lower limits of normal prior to starting study drug (supplementation allowed): potassium, magnesium, calcium
Patient must have the following laboratory values or have the following laboratory values corrected with supplements to be above the lower limit of normal before the first dose of ceritinib:\r\n* Potassium\r\n* Magnesium\r\n* Phosphorus\r\n* Total calcium (corrected for serum albumin)
Unacceptable electrolyte values, including:\r\n* Potassium < 4.0 mmol/L despite supplementation, or elevated potassium above the CTCAE grade 1 upper limit\r\n* Magnesium below the lower limit of normal range despite supplementation, or elevated magnesium above the CTCAE grade 1 upper limit\r\n* Ionized calcium or corrected calcium values below the normal range or hypercalcemia above the CTCAE grade 1 upper limit
Serum phosphorus, calcium, magnesium and potassium >= lower limit of normal
Calcium >= lower limit of normal
Potassium, magnesium, phosphorus and total calcium values ? LLN (lower limit of normal)
Calcium >= lower limit of normal (=< 48 hours prior to enrollment/randomization)
Calcium >= lower limit of normal (=< 48 hours prior to registration)
Normal serum potassium (K+), magnesium (Mg+), phosphates (PO4), and total Ca++ (calcium) (pre-treatment abnormal values may be therapeutically corrected before starting therapy and must be documented as normal or if abnormal values persist must be documented as clinically insignificant)
Magnesium, potassium and calcium < the lower limit of normal per institution normal lab values
Magnesium > the lower limit of normal per institution normal lab values
Potassium > the lower limit of normal per institution normal lab values
Calcium > the lower limit of normal per institution normal lab values
Magnesium or potassium lower than the normal institutional values
Magnesium, potassium and calcium > the lower limit of normal per institution normal lab values
Magnesium >= the lower limit of normal per institution normal lab values
Potassium >= the lower limit of normal per institution normal lab values
Calcium >= the lower limit of normal per institution normal lab values
Magnesium, potassium and calcium > the lower limit of normal per institution normal lab values