Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Other unspecified reasons that, in the opinion of the investigator, make the patient unsuitable for enrollment
Any condition which makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Subjects, in the opinion of the Investigator, who are unsuitable to participate in the study.
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Other unspecified reasons that, in the opinion of the Investigator, make the subject unsuitable for enrollment.
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Subject has any condition which makes the subject unsuitable for study participation.
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Chronic alcohol or drug abuse or any condition that, in the Investigator's opinion, makes him/her an unreliable trial subject, unlikely to complete the trial, or unable to comply with the protocol procedures.
Any other medical condition or laboratory evaluation that, in the treating physician's or principal investigator's opinion, makes the patient unsuitable to participate in this clinical trial
Any other conditions or circumstances that would, in the opinion of the investigator, make the patient unsuitable for participation in the study
Any condition which, in the investigator's opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Clinically significant abnormalities or co-morbidities, other than HCV infection that in opinion of the investigator makes subject unsuitable for this study or drug regimen
Any other clinical condition, psychiatric condition or prior therapy that, in the opinion of the Investigator, would make the subject unsuitable for the study or unable or to comply with follow-up visits
Any other condition or prior therapy that, in the opinion of the Investigator, would make the subject unsuitable for the study or unable to comply with the protocol
Any new or uncontrolled condition that could make the patient unsuitable for participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Other unspecified reasons that, in the opinion of the investigator, make the subject unsuitable for the study
ARM A: Any condition, which in the opinion of the investigator would render the patient unsuitable to participate in the study
ARM B: Any condition, which in the opinion of the investigator would render the patient unsuitable to participate in the study
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which in the investigator’s opinion makes the subject unsuitable for study participation
Subject has any condition which makes the subject unsuitable for study participation.
Any condition which, in the investigator’s opinion, makes the patient unsuitable for trial participation
Inability to comply with protocol and /or not willing or not available for follow-up assessments or any condition which in the investigator's opinion makes the patient unsuitable for the study participation
Any other medical condition or laboratory evaluation that, in the treating physician’s or principal investigator’s opinion, makes the patient unsuitable to participate in this clinical trial
Patients may not have any other medical condition or reason, in that investigator's opinion, makes the patient unstable to participate in a clinical trial
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator's opinion, makes the subject unsuitable for trial participation.
Presence of any condition which makes the patient unsuitable
Concurrent corneal disorder or ophthalmologic condition making subject unsuitable
Subject has any condition which makes the subject unsuitable for study participation, including any contraindications of azacitidine.
Any condition which, in the investigator's opinion, makes the subject unsuitable for trial participation
Any medical condition which, in the investigator's opinion, makes the patient unsuitable for participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Have any past or current, acute or chronic concurrent medical condition/illness or therapy that, in the opinion of the investigator, would make the subject unsuitable for the clinical trial or unable to comply with follow up visits
Subject has any condition which makes the subject unsuitable for study participation (e.g. ophthalmic conditions such as advanced cataracts).
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator's opinion, makes the subject unsuitable for trial participation.
Any other condition or prior therapy, which in the opinion of the PI, would make the subject unsuitable for the study.
Other unspecified reasons that, in the opinion of the investigator or sponsor, make the subject unsuitable for enrollment
Any condition which in the investigator's opinion makes the subject unsuitable for study participation
Other unspecified reasons that, in the opinion of the investigator or Millennium, make the patient unsuitable for enrollment
Any other condition or circumstance that would, in the opinion of the investigator, make the patient unsuitable for participation in the study
Any other medical condition or laboratory evaluation that, in the treating physician’s or principal investigator's opinion, makes the patient unsuitable to participate in this clinical trial
Patients with any other medical condition or reason, in that investigator’s opinion, makes the patient unstable to participate in a clinical trial
Subject has concurrent corneal disorder or any ophthalmologic condition which, in the investigator's opinion, makes the subject unsuitable for study participation (i.e., advanced cataracts, glaucoma).
Subject has any condition which, in the investigator's opinion, makes the subject unsuitable for study participation.
Any condition, which, in the site investigator's opinion, makes the subject unsuitable for trial participation.
Subject has concurrent corneal disorder or any ophthalmologic condition that makes the subject unsuitable for study participation (e.g., advanced cataracts, glaucoma).
Subject has concurrent corneal disorder or any ophthalmologic condition which makes the subject unsuitable for study participation .
Subject has any condition which makes the subject unsuitable for study participation.
In opinion of Investigator, make subject unsuitable for study.
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
The subject is judged unsuitable for study participation by the Investigator for any other reason.
Any condition that, in the opinion of the investigator or the Sponsor, makes the patients unsuitable for the study.
Subject with significant or uncontrolled cardiac, renal, hepatic or other systemic disorders; or significant psychological conditions at baseline that in the investigator's opinion, makes the subject unsuitable for study participation.
Any condition which in the investigator's opinion makes the patient unsuitable for study participation.
Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation
Any condition which in the investigator's opinion makes the patient unsuitable for the study participation
Any other condition that, in the opinion of the investigator, would make the subject unsuitable for enrollment or could interfere with the subject participating in and completing the protocol.
Subject has any condition which may require treatment during the study and may make the subject unsuitable for study participation.
Subject has concurrent corneal disorder or any ophthalmologic condition which, in the Investigator's opinion, makes the subject unsuitable for study participation (e.g., advanced cataracts, glaucoma, or subject is unable to undergo a comprehensive ophthalmologic exam).
Any other condition which, in the opinion of the investigator, would make the subject unsuitable for trial participation
Any other medical condition or laboratory evaluation that, in the treating physician‘s or principal investigator's opinion, makes the patient unsuitable to participate in this clinical trial
Any other condition or intercurrent illness that, in the opinion of the investigator, makes the participant a poor candidate for the trial
Any other condition or intercurrent illness that, in the opinion of the investigator, makes the participant a poor candidate for the trial
Other unspecified reasons that, in the opinion of the investigator or TARIS, make the subject unsuitable for enrollment.
Have significant comorbidities, that in the judgment of the investigator makes the subject unsuitable for standard dose induction chemotherapy (e.g. anthracycline and infusional cytarabine given as 7+3), or;
Have significant comorbidities, that in the judgment of the investigator makes the subject unsuitable for standard dose induction chemotherapy (e.g., anthracycline and infusional cytarabine given as 7+3); or
Any other condition or intercurrent illness that, in the opinion of the investigator, makes the participant a poor candidate for the trial
Any medical or psychological condition or any reason that, according to the investigator’s judgment, makes the patient unsuitable for participation in the study
Any condition which in the investigator’s opinion makes the subject unsuitable for study participation
Conditions unsuitable for participation in the trial in the investigator's opinion
Any other condition or intercurrent illness that in the opinion of the investigator makes the subject a poor candidate for participation in the trial such as recent cardiac event
Any other condition or intercurrent illness that in the opinion of the investigator makes the subject a poor candidate for participation in the trial such as recent cardiac event
Intercurrent illness which makes potential participant unsuitable for study or started hormone replacement therapy between RPFNA and enrollment on study
Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for core biopsy or the trial
Any other condition that, in the opinion of the investigator, makes the patient or donor ineligible for the study
Any other condition or intercurrent illness that in the opinion of the investigator makes the subject a poor candidate for RPFNA or the trial
Any condition which would make the subject, in the opinion of the investigator, unsuitable for the study
Any other condition which, in the opinion of the investigator, makes the patient ineligible for the study Inclusion Criteria Donor:
Any condition which in the investigator’s opinion makes the patient unsuitable for the study participation
It is determined by the investigator that the subject is clinically unsuitable for the study
Acute major illness (e.g., unstable angina, etc.) or other condition that makes participation unsafe, per the investigator’s judgement
Subject has any condition which makes the subject unsuitable for study participation.
Determined by investigator to be clinically unsuitable for the study
Any other criteria, in the opinion of the investigator that would make the subject unsuitable for study participation.
Serious medical risk factors involving any of the major organ systems, or serious psychiatric disorders that could compromise the patient's safety or the study data integrity.
Any medical conditions, which, in the opinion of the investigators, would jeopardize either the patient or the integrity of the data obtained are not eligible
Patients with medical conditions, which, in the opinion of the investigators, would jeopardize either the patient or the integrity of the data obtained will not be eligible
Any condition(s), medical or otherwise, which, in the opinion of the investigators, would jeopardize either the patient or the integrity of the data obtained
Medical conditions which, in the opinion of the investigators, would jeopardize the patient or the integrity of the data obtained
Patients with medical conditions, which, in the opinion of the investigators, would jeopardize either the patient or the integrity of the data obtained will not be eligible
Patients with medical conditions, which, in the opinion of the investigators, would jeopardize either the patient or the integrity of the data obtained will not be eligible
Concurrent illness, such as known psychiatric disorders or substance abuse (i.e., average alcohol consumption of more than 3 drinks per day), which in the opinion of the investigators would compromise either the patient or the integrity of the data
Concurrent illness, such as known psychiatric disorders or substance abuse (i.e., average alcohol consumption of more than 5 drinks per day), which in the opinion of the investigators would compromise either the patient or the integrity of the data
Concurrent illness which in the opinion of the investigators would compromise either the patient or the integrity of the data
Participants must not have uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that in the opinion of investigators would jeopardize patient safety of data integrity; Note: individuals who are human immunodeficiency virus (HIV) positive will not necessarily be excluded, will be considered on a case-by-case basis, but will be required to meet criteria related to patient safety and data integrity, as assessed by investigators
Concurrent illness which in the opinion of the investigators would compromise either the patient or the integrity of the data
Patients with uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that in the opinion of investigators would jeopardize patient safety of data integrity are excluded; individuals who are human immunodeficiency virus (HIV) positive will not necessarily be excluded, will be considered on a case-by-case basis, but will be required to meet criteria related to patient safety and data integrity, as assessed by investigators
Any serious concurrent condition that could, in the investigator’s opinion, significantly interfere with completion of study procedures or protocol compliance
Any serious, unstable medical or psychiatric condition that would prevent, (as judged by the investigator) the subject properly providing informed consent or any condition which would jeopardize compliance with the protocol
Concurrent condition that in the investigator’s opinion would jeopardize compliance with the protocol
Uncontrolled or progressive systemic disease or other concurrent condition which in the Investigator’s opinion makes HD-MTX an undesirable treatment option for the patient or would jeopardize compliance
Active bleeding diatheses, which in the investigator’s opinion makes it undesirable for the patient to participate in the trial or which would jeopardize compliance with the protocol
Signs or symptoms of organ failure, major chronic illnesses other than cancer, or any concomitant medical or social conditions which, in the opinion of the investigator, make it undesirable for the patient to participate in the study, or which could jeopardize compliance with the protocol
Any serious and/or unstable pre-existing medical, psychiatric, or other condition (e.g., severe hepatic impairment) or current unstable or uncompensated respiratory or cardiac conditions which makes it undesirable for the patient to participate in the study or which could jeopardize compliance with the protocol.
No evidence of severe or uncontrolled other systemic disease or any concurrent condition which in the investigator’s opinion makes it undesirable for the subject to participate in the trial or which would jeopardize compliance with the protocol
Concurrent condition that in the investigator's opinion would jeopardize compliance with the protocol or would impart excessive risk associated with study participation that would make it inappropriate for the patient to be enrolled.
Any concurrent condition which in the investigator’s opinion makes it undesirable for the subject to participate in this trial or which would jeopardize compliance with the protocol
Subjects with any concurrent condition that, in the investigator's opinion, would jeopardize the safety of the subject or compliance with the protocol
Evidence of severe or uncontrolled systemic disease or any concurrent condition which in the Investigator’s opinion makes it undesirable for the patient to participate in the trial or which would jeopardize compliance with the protocol
Has any condition that, in the opinion of the investigator, might jeopardize the safety of the patient or interfere with protocol compliance
Significant psychiatric disorder and any other reason in the Investigator’s opinion that would jeopardize protocol compliance or compromise the patient’s ability to give informed consent
Significant psychiatric disorder and any other reason in the Investigator’s opinion that would jeopardize protocol compliance or compromise the patient’s ability to give informed consent
Subjects with any concurrent condition that, in the investigator’s opinion, would jeopardize the safety of the subject or compliance with the protocol
Evidence of severe or uncontrolled systemic disease or any concurrent condition which in the investigator’s opinion makes it undesirable for the patient to participate in the trial or which could jeopardize compliance with the protocol
Unstable or clinically significant concurrent medical condition that would, in the opinion of the investigator, jeopardize the safety of a subject and/or compliance with the protocol.
Evidence of severe or uncontrolled systemic disease or any concurrent condition that, in the opinion of the Investigator or Medical Monitor, makes it undesirable for the subject to participate in the study or that would jeopardize compliance with the protocol. Subjects with pre-existing well-controlled diabetes are not excluded.
Has any condition that, in the opinion of the investigator, might jeopardize the safety of the subject or interfere with protocol compliance.
Any condition that, in the opinion of the investigator, might jeopardize the safety of the subject or interfere with protocol compliance.
Uncontrolled intercurrent illness or any concurrent condition that, in the Investigator's opinion, would jeopardize the safety of the patient or compliance with the protocol
Any other concurrent condition that in the investigator’s opinion would jeopardize compliance with the protocol
Any other concurrent condition that in the investigator's opinion would jeopardize compliance with the protocol
Unstable or clinically significant concurrent medical condition that would, in the opinion of the investigator, jeopardize the safety of a subject and/or compliance with the protocol
Any concurrent condition which in the investigator’s opinion makes it undesirable for the subject to participate in this trial or which would jeopardize compliance with the protocol
Unstable or clinically significant concurrent medical condition that would, in the opinion of the investigator, jeopardize the safety of a patient and/or their compliance with the protocol.
Patients with any clinically significant medical condition which, in the opinion of the investigator, makes it undesirable for the patient to participate in the study or which could jeopardize compliance with protocol requirements including, but not limited to: ongoing or active infection, significant uncontrolled hypertension, or severe psychiatric illness/social situations
Have signs or symptoms of end organ failure, major chronic illnesses other than cancer, or any severe concomitant conditions which, in the opinion of the investigator, make it undesirable for the patient to participate in the study, or which could jeopardize compliance with the protocol
Concurrent medical condition that would jeopardize compliance.
Evidence of severe or uncontrolled systemic disease or any concurrent condition – including, but not limited to symptomatic congestive heart failure, unstable angina pectoris, unstable hypertension, seizure disorder, or psychiatric illness – which in the Investigator’s opinion makes it undesirable for the patient to participate in the trial or which would jeopardize compliance with the protocol
Any concurrent condition which in the investigator's opinion makes it undesirable for the patient to participate in the trial or which would jeopardize compliance with the protocol.
Have signs or symptoms of organ failure, major chronic illnesses other than cancer, or any concomitant medical or social condition that, in the opinion of the investigator, make it undesirable for the patient to participate in the study or that could jeopardize compliance with the protocol.
Subjects with any concurrent condition that, in the investigator’s opinion, would jeopardize the safety of the subject or compliance with the protocol
Patients must not have any concurrent condition which in the Investigator’s opinion makes it inappropriate for the patient to participate in the trial or which would jeopardize compliance with the protocol
Any condition that in the opinion of the investigator raises concerns about protocol compliance
Unstable or clinically significant concurrent medical condition that would, in the opinion of the investigator or medical monitor, jeopardize the safety of a subject and/or their compliance with the protocol.
Evidence of severe or uncontrolled systemic disease or any concurrent condition which in the investigator’s opinion makes it undesirable for the patient to participate in the trial or which would jeopardize compliance with the protocol
Any other concurrent condition that in the investigator's opinion would jeopardize compliance with the protocol
Any other concurrent condition that in the investigator's opinion would jeopardize compliance with the protocol
Concurrent condition that in the investigator's opinion would jeopardize compliance with the protocol or would impart excessive risk associated with study participation that would make it inappropriate for the patient to be enrolled.