Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy.
A serious uncontrolled medical disorder that in the opinion of the investigator would impair the ability of the subject to receive protocol therapy
Any serious uncontrolled medical disorder or active infection that would impair the subject’s ability to receive investigational product, such as conditions associated with frequent diarrhea
Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy.
Subjects with a medical or psychological impediment that would impair the ability of the subject to receive therapy per protocol or impact ability to comply with the protocol or protocol-required visits and procedures
A serious uncontrolled medical disorder or active infection, which would impair the ability of the subject to receive protocol therapy
A serious uncontrolled medical disorder or active infection that would impair their ability to receive study treatment
A serious uncontrolled medical disorder or active infection that would impair their ability to receive study treatment
A serious uncontrolled medical disorder or active infection that would impair their ability to receive study treatment
A serious uncontrolled medical disorder or active infection that in the investigator’s opinion would impair the patient’s ability to receive study treatment
Serious uncontrolled medical disorder or active infection that in the investigator's opinion would impair the patient's ability to receive study treatment.
Any other serious uncontrolled medical disorder or active infection that would impair the patient’s ability to receive study treatment (at the discretion of the investigator)
A serious uncontrolled medical disorder that is in the opinion of the Investigator would impair the ability of the subject to receive protocol therapy
Any serious uncontrolled medical disorder that would impair the ability of the subject to receive protocol-driven therapy
Serious uncontrolled medical disorder or active infection that would impair the patient's ability to receive study treatment.
Any serious or uncontrolled medical disorder or active infection that would impair the ability of the subject to receive protocol therapy.
A serious uncontrolled medical disorder or active infection that would impair the ability of the subject to receive protocol therapy
A serious uncontrolled medical disorder that in the opinion of the Investigator would impair the ability of the subject to receive protocol therapy
Subjects with a medical or psychological impediment that would impair the ability of the subject to receive therapy per protocol or impact ability to comply with the protocol or protocol-required visits and procedures
Active infection that would impair the ability of the patient to receive study treatment
Any serious uncontrolled medical disorder or active infection that would impair the subject’s ability to receive investigational product, such as conditions associated with frequent diarrhea
A serious uncontrolled medical disorder that, in the opinion of the Investigator, would impair the ability of the patient to receive protocol therapy
Active infection that would impair the ability of the patient to receive study treatment
Serious uncontrolled medical disorder or active infection which would impair the ability of the subject to receive protocol therapy or whose control would be jeopardized by protocol therapy
Severe or uncontrolled medical disorder that would, in the investigator's opinion, impair ability to receive study treatment (i.e., uncontrolled diabetes, chronic renal disease, chronic pulmonary disease or active, uncontrolled infection)
A serious uncontrolled medical disorder or active infection that would impair their ability to receive study treatment
A serious uncontrolled medical disorder/condition that in the opinion of the Investigator would impair the ability of the subject to receive protocol therapy
Serious uncontrolled medical disorder, or active infection, that would impair the ability of the patient to receive protocol therapy.
Any serious, uncontrolled medical disorder that would impair the ability of the subject to receive protocol driven therapy
Any active disease condition which would render the protocol treatment dangerous or impair the ability of the patient to receive protocol therapy.
Any serious uncontrolled, medical or psychological disorder that would impair the ability of the patient to receive therapy
Acute or chronic medical disorder that, in the opinion of the investigator, would impair the ability of the subject to receive protocol treatment
A serious uncontrolled medical disorder that is in the opinion of the investigator would impair the ability of the subject to receive protocol therapy
A serious uncontrolled medical disorder that in the opinion of the Investigator would impair the ability of the subject to receive protocol therapy
A serious uncontrolled medical disorder or active infection that would impair the ability of the subject to receive protocol therapy in case re-initiation of dasatinib is needed.
Serious intercurrent infections or non-malignant medical illnesses that are uncontrolled
Poor medical risk because of other conditions such as uncontrolled systemic diseases, active uncontrolled infections, or comorbidities that may put the patient at risk of not being able to complete at least 2 cycles of treatment.
Non-malignant medical illnesses that are uncontrolled or whose control may be jeopardized by study treatment, such as severe hereditary coagulation disorders or insulin-dependent diabetes mellitus that is not optimally controlled with medical management (example, presence of ketoacidosis)
Patients who have any severe and/or uncontrolled medical conditions or other conditions that could affect their participation in the study such as:\r\n* Severely impaired lung function\r\n* Any active (acute or chronic) or uncontrolled infection/disorders\r\n* Nonmalignant medical illnesses that are uncontrolled or whose control may be jeopardized by the treatment with the study therapy\r\n* Psychiatric illness/social situations that would limit compliance with study requirement
Patients with serious intercurrent infections, or nonmalignant medical illnesses that are uncontrolled or whose control may be jeopardized by the complications of this therapy
Poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection.
Any serious or uncontrolled medical disorder or active infection
At high medical risk because of non-malignant systemic disease including uncontrolled infection
Uncontrolled infection or other serious medical illnesses.
Medical suitability for resection, including documented medical and cardiac clearance
Serious intercurrent infections or non-malignant medical illness that are uncontrolled or the control of which may be jeopardized by this therapy.
Any medical conditions that, in the investigator’s opinion, would impose excessive risk to the subject, e.g., any uncontrolled disease, such as pulmonary disease, infection, seizure disorder, uncontrolled hyperglycemia
Unstable medical comorbidities (i.e. uncontrolled cardiac comorbidities)
A serious uncontrolled medical disorder that in the opinion of the investigator may be jeopardized by the treatment with protocol therapy
A serious uncontrolled medical condition requiring therapy
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection
Serious concurrent infection or nonmalignant illness that is uncontrolled or whose control may be jeopardized by complication of study therapy
Patients being considered at poor medical risk due to a serious, uncontrolled medical disorder or non-malignant systemic disease.
Serious intercurrent infections or non-malignant medical illness that are uncontrolled or the control of which may be jeopardized by this therapy
Uncontrolled medical illnesses
Has any other severe, uncontrolled medical condition, including uncontrolled DM or unstable CHF
Patients with active or uncontrolled infections or with serious illnesses or medical conditions which would not permit the patient to be managed according to the protocol. This includes but is not limited to:
Patients have a severe and/or uncontrolled medical disease (i.e., uncontrolled diabetes, chronic renal disease, or active uncontrolled infection)
Serious uncontrolled medical disorder or uncontrolled active systemic infection or current unstable or decompensated respiratory or cardiac conditions which makes it undesirable or unsafe for the patient to participate in the study
Uncontrolled medical problems
Uncontrolled medical problems
A serious uncontrolled medical disorder that in the opinion of the investigator may be jeopardized by the treatment with protocol therapy
Patients who have any severe and/or uncontrolled medical conditions or other conditions that could affect their participation in the study such as any active (acute or chronic) or uncontrolled infection/ disorders or nonmalignant medical illnesses that are uncontrolled or whose control may be jeopardized by the treatment with the study therapy
Serious concurrent uncontrolled medical disorder
Patients must not be considered a poor medical risk due to a serious, uncontrolled medical disorder, nonmalignant systemic disease or active, uncontrolled infection.
Poor medical risk because of systemic diseases (e.g. active uncontrolled infections) in addition to the qualifying disease under study.
Acute and chronic, active infectious disorders and non malignant medical illnesses that are uncontrolled or whose control may be jeopardized by the complications of this study therapy
Has any of the following medical conditions: uncontrolled diabetes, psychiatric disorder (including dementia) that prevents compliance with protocol, uncontrolled seizures, newly diagnosed deep vein thrombosis, active systemic infection that is likely to interfere with study procedure or results
Patients must have no non-malignant medical illnesses that are uncontrolled or whose control may be jeopardized by the treatment with protocol therapy
Serious uncontrolled medical disorder
Serious intercurrent infections or non-malignant medical illness that are uncontrolled or the control of which may be jeopardized by this therapy
Severe or uncontrolled medical conditions (i.e., uncontrolled diabetes, active or uncontrolled infection)
Any serious or uncontrolled medical disorder or active infection
Patients have a severe and/or uncontrolled medical disease (i.e., uncontrolled diabetes, chronic renal disease, or active uncontrolled infection)
Uncontrolled hypothyroidism
Serious intercurrent infections or non-malignant medical illnesses that are uncontrolled
Uncontrolled or unstable medical or psychiatric co-morbidities which would clearly preclude use of MLN8237 or erlotinib
Nonmalignant medical illnesses that are uncontrolled or a controlled illness that may be jeopardized by the treatment with protocol therapy
Subjects considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease, or active, uncontrolled infection;
Considered a poor medical risk due to a serious uncontrolled disorder
Acute and chronic active infectious disorders and non-malignant medical illnesses that are uncontrolled or whose control may be jeopardized by the complications of this study therapy
Uncontrolled or severe concurrent medical condition (including uncontrolled brain metastases).
Patients with any concurrent severe and/or uncontrolled medical condition or active uncontrolled systemic infection as determined by the investigator
Uncontrolled or severe concurrent medical condition (including uncontrolled brain metastases).
Serious intercurrent infections or non-malignant medical illnesses that are uncontrolled or the control of which may be jeopardized by this therapy
Uncontrolled or unstable medical or psychiatric co-morbidities which would clearly limits patients participation
Uncontrolled or severe concurrent medical condition (including uncontrolled brain metastases).
Serious or uncontrolled medical disorder (including infection or cardiovascular disease) or dementia or other serious psychiatric condition
Patients with serious intercurrent infections, or nonmalignant medical illnesses that are uncontrolled or whose control may be jeopardized by the complications of this therapy
Uncontrolled infection or concomitant medical illness that is not adequately controlled with current medical management, as determined per clinician discretion
High medical risks because of non-malignant systemic disease or with active uncontrolled infection;
Unstable medical illnesses
Patient is considered a poor medical risk due to a serious, uncontrolled medical disorder, non malignant systemic disease, or active, uncontrolled infection.
Presence of a serious uncontrolled medical disorder.
For participants who are randomized in aim 1:\r\n* No uncontrolled serious medical or psychiatric condition(s) that would affect the patient’s ability to participate in the interventional study, e.g., uncontrolled hypertension, symptomatic cardiac disease, or severe/uncontrolled depression as indicated by a Patient Health Questionnaire (PHQ-9) score > 9 (Kroenke)\r\n* No diagnoses of any other invasive malignancy other than endometrial cancer or non-melanoma skin cancer which required active treatment currently
Uncontrolled hypothyroidism
Uncontrolled hypothyroidism
Must have no known medical problems and have had a full medical exam within 6 months of the study
Patients with severe uncontrolled medical problems are not eligible for this trial.
No uncontrolled serious medical problems except for the diagnosis of cancer.
The patient has another concurrent illness that would preclude study conduct and assessment, including, but not limited to, another active malignancy (excluding squamous or basal cell skin cancer and in situ cervical cancer), uncontrolled medical conditions, uncontrolled and active infection (considered opportunistic, life threatening, or clinically significant), uncontrolled risk of bleeding, or uncontrolled diabetes mellitus.
Serious concurrent uncontrolled medical disorder.
Patients considered at poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, extensive bilateral lung disease on high resolution computed tomography scan or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, unstable spinal cord compression, superior vena cava syndrome, symptomatic congestive heart failure, unstable angina pectoris, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent and would limit compliance with study requirements
Participants considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, corrected QT interval (QTc) prolongation > 470 msec, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, unstable spinal cord compression (untreated and unstable for at least 28 days prior to study entry), extensive bilateral lung disease with less than 20% predicted lung function by carbon monoxide diffusing capability test (DLCO) (Lung Diffusion Capacity Testing), or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Any other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or may interfere with the interpretation of study results\r\n* Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, superior vena cava syndrome, extensive bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Subjects considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan, history of pneumonitis, or any psychiatric disorder that prohibits obtaining informed consent.
Any underlying medical or psychiatric condition, which in the opinion of the Investigator, will make the administration of study drug hazardous or obscure the interpretation of adverse events. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, superior vena cava syndrome, extensive bilateral lung disease on high-resolution computed tomography scan, uncontrolled seizures or any psychiatric disorder that prohibits obtaining informed consent.
Patients must not be considered a poor medical risk due to a serious, uncontrolled medical disorder, nonmalignant systemic disease, or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 90 days) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, or any psychiatric disorder that prohibits obtaining informed consent
Poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, unstable spinal cord compression (untreated or unstable within at least 28 days prior to registration), superior vena cava syndrome, extensive bilateral lung disease on high-resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, unstable spinal cord compression (untreated and unstable for at least 28 days prior to study entry), superior vena cava syndrome, extensive bilateral lung disease on high resolution CT scan or any psychiatric disorder that prohibits obtaining informed consent
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection.  Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent.
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 5 years) myocardial infarction, uncontrolled major seizure disorder, uncontrolled hypertension (blood pressure [BP] ? 160/100), stroke within the past 5 years, uncontrolled diabetes (hemoglobin [hgb] A1C >7), unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent
Uncontrolled non-malignant systemic disease or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent.
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent and would limit compliance with study requirements
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, or any psychiatric disorder that prohibits obtaining informed consent; evidence of severe or uncontrolled systemic disease or any concurrent condition which, in the investigator's opinion, makes it desirable for the patient to participate in the trial or which would jeopardize compliance with the protocol
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active/uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, extensive interstitial bilateral lung disease on high resolution computed tomography (HRCT) scan or any psychiatric disorder that prohibits obtaining informed consent.
Poor medical risk due to a serious, uncontrolled medical disorder, nonmalignant systemic disease, or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 90 days) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, uncontrolled hypertension, or any psychiatric disorder that prohibits obtaining informed consent
Poor medical risk due to a serious, uncontrolled medical disorder, nonmalignant systemic disease or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, recent (within 90 days) myocardial infarction, uncontrolled major seizure disorder, unstable spinal cord compression, superior vena cava syndrome, uncontrolled hypertension, or any psychiatric disorder that prohibits obtaining informed consent
Other serious, uncontrolled medical disorder, non-malignant systemic disease, or active, uncontrolled infection (including uncontrolled human immunodeficiency virus [HIV], hepatitis B or C), or any psychiatric disorder that prohibits obtaining informed consent
Participants considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection; examples include, but are not limited to, corrected QT interval (QTc) prolongation > 470 msec, uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction, unstable spinal cord compression (untreated and unstable for at least 28 days prior to study entry), superior vena cava syndrome, extensive bilateral lung disease with less than 20% predicted lung function by diffusion capacity of the lungs for carbon monoxide (DLCO) (lung diffusion capacity testing), or any psychiatric disorder that prohibits obtaining informed consent
Active uncontrolled infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment
Active infection or serious underlying medical condition that would impair the ability of the patient to received protocol therapy
History of any psychiatric condition that might impair patient's ability to understand or comply with the requirements of the study or to provide consent
Active infection or serious underlying medical condition that would impair the ability of the patient to received protocol therapy
History of any psychiatric condition that might impair patient's ability to understand or comply with the requirements of the study or to provide consent
Patients who are immunosuppressed (including known HIV infection), have a serious active infection at the time of treatment, have known hepatitis C, or have any serious underlying medical condition that would impair the ability of the patient to receive protocol treatment.
Patient has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive study treatment or undergo study procedures
Has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the subject to receive protocol treatment.
Serious active infection at the time of enrolment, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment
Subjects must not have a history of other serious underlying medical or psychiatric condition that, in the opinion of the investigator, would impair the ability to receive, tolerate and or comply with the planned treatment and follow-up
Any condition that, in the opinion of the investigator, would impair the subject's ability to comply with study procedures.
Serious underlying medical conditions that, per the Investigator's discretion, could impair the ability of the patient to participate in the trial
Active infection or other serious underlying medical condition which would impair the ability of the patient to receive the planned treatment
Any serious underlying medical condition that, in the opinion of the enrolling physician, would impair the ability of the patient to receive protocol treatment
Active infection or any serious underlying medical condition, which would impair the ability of the patient to receive protocol treatment.
Presence of a comorbid disease or medical condition that would impair the ability of the patient to receive or comply with the study protocol
Patients with any serious underlying medical condition that would impair their ability to receive or tolerate the planned treatment.
Serious active infection at the time of study entry, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment
Comorbid disease or a medical or psychiatric condition that would impair the ability of the patient to receive or comply with the study protocol.
Serious active infection at the time of study entry, or another serious underlying medical condition that would impair the ability of the patient to receive study treatment.
Any other condition that, in the opinion of the Investigator, would impair the patient’s ability to comply with study procedures
Patients who have post-obstructive pneumonia or other serious infection at the time of registration or other serious underlying medical condition that would impair the ability of the patient to receive protocol treatment
Subjects must not have post-obstructive pneumonia or other serious infection at the time of registration or other serious underlying medical condition that would impair the ability of the subjects to receive protocol treatment
Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment
Any severe underlying medical conditions including presence of laboratory abnormalities, which could impair the ability to participate in the study or the interpretation of its results.
Any condition that in the opinion of the investigator would impair the patients' ability to comply with the study procedures.
Active infection or any serious underlying medical condition, which would impair the ability of the patient to receive protocol treatment
Serious active infection, or serious underlying medical condition.
Patient has an active uncontrolled infection, including a urinary tract infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment.
Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment
Serious active infection at the time of treatment, or another serious underlying medical condition that would impair the ability of the patient to receive protocol treatment.
Any other condition that, in the opinion of the investigator, would impair the patient's ability to comply with study procedures
Serious underlying medical condition which would impair the ability of the patient to receive protocol treatment, in the opinion of the treating physician
Active infection or serious underlying medical condition that would impair the patient's ability to receive protocol treatment
Patients with any serious underlying medical condition that would impair their ability to receive or tolerate the planned treatment
E 13. Any severe acute or chronic medical condition which could impair the ability of the participant to participate to the study or interfere with interpretation of study results, or participants unable to comply with the study procedures.
No active serious infection or other comorbid illness which would impair ability to participate in the trial
Any serious underlying medical or psychiatric condition (e.g., alcohol or drug abuse), dementia or altered mental status or any issue that would impair the ability of the patient to receive or tolerate the planned treatment, to understand informed consent or that in the opinion of the investigator would contraindicate the patient's participation in the study or that would confound the results of the study.
Any clinically significant condition or situation, other than the condition being studied that, in the opinion of the investigator, would impair with their ability to receive or tolerate the planned treatment, or interfere with the study evaluations or optimal participation in the study.
Serious underlying medical condition which would impair the ability of the patient to receive protocol treatment, in the opinion of the treating physician
Any serious, active underlying medical condition that would impair the ability of the subjects to receive study treatment
Any serious underlying medical condition that, in the opinion of the investigator or medical monitor, would impair the ability to receive or tolerate the planned treatment
Active uncontrolled infection, underlying medical condition including unstable cardiac disease, or other serious illness impairing the ability of the patient to receive protocol treatment.
Any severe acute or chronic medical condition, which could impair the ability of the patient to participate to the study or to interfere with interpretation of study results
Serious active infection at the time of randomization, or other serious underlying medical conditions that would impair the ability of the participant to receive protocol treatment
Any serious underlying medical condition that, in the opinion of the investigator or medical monitor, would impair their ability to receive or tolerate the planned treatment
Serious active infection at time of randomization or other serious underlying medical conditions that would impair the ability of the participant to receive protocol treatment
A serious underlying medical condition that would impair the ability of the patient to receive protocol treatment
Patients must not have serious infection or other serious underlying medical condition which would impair the ability of the patient to receive protocol treatment; these need not be specified in the history and physical and can be documented through signature on the eligibility checklist; severe, active co-morbidity, defined as follows:
Underlying medical condition including unstable cardiac disease, or other serious illness that would impair the ability of the patient to undergo treatment
Any medical condition that may interfere with ability to receive protocol treatment
Any condition that, in the opinion of the investigator, would impair the subject's ability to comply with study procedures;
Serious underlying medical condition that would impair the ability of the patient to receive protocol treatment, specifically cardiac diseases, uncontrolled hypertension or renal diseases
No serious medical or psychiatric illnesses that would prevent informed consent; patients with post-obstructive pneumonia are eligible; patients with an active serious infection or other serious underlying medical condition that would otherwise impair their ability to receive protocol treatment are ineligible
Any medical condition that may interfere with ability to receive protocol treatment
Patient has an active uncontrolled infection, underlying medical condition, or other serious illness that would impair the ability of the patient to receive protocol treatment
Any condition that, in the opinion of the principal investigator, would impair the patient’s ability to comply with study procedures
Any condition that, in the opinion of the principal investigator, would impair the patient’s ability to comply with study procedures
Serious underlying medical condition that would impair patient's ability to tolerate the imaging procedure
A serious underlying medical condition that would otherwise impair the patient’s ability to receive treatment and imaging studies
Presence of a comorbid disease or medical condition that would impair the ability of the patient to receive or comply with the study protocol