Serum creatinine below the upper limit of the institutional normal range (ULN) or creatinine clearance ? 60 mL/min/1.73 m2 for patients with serum creatinine levels above institutional ULN.
Creatinine < 1.5 x institutional upper limit of normal or creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< institutional upper limit or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above 1.5 x upper limit of normal
Creatinine =< 1.5 x IULN or >= 60 ml/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73m^2 for patients with creatinine levels above institutional normal
INCLUSION CRITERIA FOR SECOND-LINE THERAPY: Serum creatinine =< 1.5 X upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
INCLUSION CRITERIA FOR THIRD-LINE THERAPY: Serum creatinine =< 1.5 X upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine < 1.5 mg/dL OR creatinine clearance ? 60 mL/min/1.73 m^2 for patients with creatinine levels > institutional normal within 14 days of registration
Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< 1.5 x the upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x the upper limit of normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine < 2 mg/dL OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (unless elevated creatinine or creatinine clearance felt by investigator to be acute and reversible)
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min by Cockcroft-Gault equation for participants with creatinine levels above institutional normal.
Serum creatinine =< 1.5 x institutional ULN, OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with serum creatinine levels above 1.5 x institutional ULN
Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine ? 1.5 x institutional ULN OR creatinine clearance ? 60 mL/min by Crockoft-Gault for participants with creatinine levels above institutional normal
Creatinine within upper normal institutional limit OR creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional ULN
Creatinine =< 1.5 x within normal institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional ULN
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with serum creatinine levels > 1.5 x higher than institutional normal
Creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Within 2 weeks prior to initiation of study treatment: Creatinine =< upper limit of institutional normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x ULN or a creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, determined within 14 days of registration
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
COHORT I: Creatinine < 2 x upper limit of normal (ULN) or creatinine clearance >= 45 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional normal
Creatinine < 2 x institution upper limit of normal OR creatinine clearance > 45 mL/min/1.73 m^2, for patients with creatinine levels above institutional normal
Creatinine =< 1.5 X institutional upper limit of normal OR measured creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine < 2 x institutional upper limit of normal OR creatinine clearance >= 50 mL/min/for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine ? 1.5 x upper limit of normal (ULN) OR creatinine clearance ? 50 mL/min/1.73 m^2 (using Cockroft Gault Formula) for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 Ml/min/1.73 m^2 for patients with creatinine levels above institutional normal.
Creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal.
Creatinine ? 1.5 x IULN OR creatinine clearance ? 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x IULN or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x upper limit of normal (ULN) OR creatinine clearance > 50 mL/min/1.73 m2 for patients with creatinine levels =< 1.5 x upper limit above institutional normal
Creatinine < institutional upper limit of normal (ULN) OR creatinine clearance >= 50 mL/min for patients with creatinine levels greater than ULN
Serum creatinine =< 1.5 x institutional upper limit of normal (IULN) and creatinine clearance >= 75 mL/min
Serum creatinine =< 1.5 x institutional ULN, OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with serum creatinine levels > 1.5 x higher than institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above normal within 14 days of treatment initiation
Creatinine clearance >= 45 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal.
Obtained with 21 days of registration: creatinine =< 2 x institutional upper limit of normal OR creatinine clearance > 60 mL/min for patients with creatinine levels greater than institutional upper limit of normal
Creatinine < 1.5 X institution upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2, for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels >= 1.5 x upper limit of normal (after the HDT/ASCT)
Creatinine < 1.5 X institution upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 2.0 OR creatinine clearance > 30 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (creatinine clearance should be calculated per institutional standard)
Serum creatinine below institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with serum creatinine levels above institutional ULN
Creatinine =< 1.5 ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
OR creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 X institutional upper limit of normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, assessed within 14 days prior to registration
Serum creatinine =< 1.5 x upper normal limit of institution's normal range or creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance > 60 mL/min for patients with creatinine levels above institutional normal
Creatinine < 1.5 x institution upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2, for patients with creatinine levels above institutional normal
Creatinine < 1.5 mg/dL OR creatinine clearance >= 50 mL/min for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance: > 60 ml/min for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 Ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal; creatinine clearance should be calculated using the actual weight from day 1 of the cycle
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance < 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (Cockcroft formula)
Creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine below institutional ULN or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< the institutional upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine ? 1.5 × ULN OR creatinine clearance ? 50mL/min/1.73 m2 for subjects with creatinine levels above institutional normal
Measured OR estimated creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine above institutional upper limit of normal (IULN) obtained no more than 28 days prior to the start of neoadjuvant endocrine therapy
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal
Creatinine < 1.5 x institutional upper limit of normal (ULN), OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels greater than 1.5 x ULN
Serum creatinine =< 1.5 x upper limit of normal or creatinine clearance >= 60 ml/min for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal or creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (within 2 weeks prior to radiotherapy)
Serum creatinine =< 1.5 × upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Within 4 weeks of preregistration: Creatinine =< institutional upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
ELIGIBILITY CRITERIA FOR REGISTRATION: creatinine =< institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (within one week of registration if patient postop, otherwise within two weeks of registration)
creatinine clearance greater than or equal to 60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x IULN OR creatinine clearance >= 40 mL/min by Cockcroft-Gault for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 X upper normal limit of institution's normal range OR creatinine clearance >= 40 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal; creatinine clearance should be determined by the Cockcroft-Gault formula or by 24-hour urine collection for determination of creatinine clearance
Creatinine level within normal institutional limit, or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine level above institutional normal
Creatinine < 1.5 x institutional upper limit of normal (ULN) OR creatinine clearance (CrCl) >= 50 mL/min/1.73 m^2 for subjects with creatinine levels greater than 1.5 x ULN
Creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine levels =< upper limit of institutional normal; or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< the institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
TUMOR BIOPSY SEQUENCING: Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels >= 1.5 x institutional upper limit of normal
TREATMENT: Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels >= 1.5 x institutional upper limit of normal
Creatinine =< 1.5 x ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 × upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 mg/dL or creatinine clearance (Cockcroft-Gault) >= 60 mL/min for patients with creatinine levels above institutional upper limit of normal (ULN)
PHASE II: Creatinine =< 1.5 mg/dL or creatinine clearance (Cockcroft-Gault) >= 60 mL/min for patients with creatinine levels above institutional upper limit of normal (ULN)
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 X institutional upper limit of normal
Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance > 60 ml/min OR > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x IULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x IULN OR calculated creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 45 mL/min/ 1.73 m^2 for participants with creatinine levels above institutional ULN
Creatinine =< 1.5 × institutional upper limit of normal OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional limit of normal
Creatinine ? 1.5 × ULN or, for patients with creatinine levels above institutional upper limit of normal, creatinine clearance must be > 60 mL/min/1.73 m^2.
Creatinine clearance >60 mL/min/1.73 m2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 Ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 X institutional upper limit of normal (ULN)
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine ? 1.5 × ULN or, for patients with creatinine levels above institutional upper limit of normal, creatinine clearance must be > 60 mL/min/1.73 m^2.
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine less than institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x University of Iowa Hospitals and Clinics (UIHC) upper limit of normal or creatinine clearance of at least 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance > 60 mL/min for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x institutional upper limits of normal or for patients with creatinine levels above 1.5 x institutional normal: creatinine clearance >= 50 mL/min/1.73 m^2 by 24 hour urine collection or estimated creatinine clearance of >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Creatinine =< 1.5 mg/dL, or creatinine clearance >= 30 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine clearance > 45 mL/min/1.73 m^2, for patients with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 40 mL/min for patients with creatinine levels above institutional normal
Serum creatinine < 2.0 mg/dL or creatinine clearance (Cockcroft) >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x IULN OR creatinine clearance > 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine less than or equal to the institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine below institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< institutional ULN or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine less than or equal to 1.5 times the ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 30 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Within 14 days of registration: Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
PHASE I: Creatinine between 0-1.3 mg/dL or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
PHASE II: Creatinine between 0-1.3 mg/dL or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine =< institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine < 1.5 X institutional upper limit of normal OR creatinine clearance >= 30 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine up to 1.5 X ULN or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine < 1.5 X institutional upper limit of normal OR calculated creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< institutional ULN or creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal or >= 50 mL/min 24-hour creatinine clearance
Creatinine < 1.5 X institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 X institutional upper limit of normal
Creatinine within 1.5 x upper limit of normal, OR creatinine clearance > 60 mL/min for patients with creatinine levels above institutional normal
PART B: Creatinine =< 1.5 X ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < 1.5 x institution upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < or equal to 1.5 x ULN or creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine ? 1.5 × ULN or creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal.
Serum creatinine =< the institutional upper limit of normal or creatinine clearance >= 40 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Serum creatinine ? 1.5 x ULN or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine < 1.5 x institutional upper limit of normal or creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional ULN or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional ULN
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x upper limit of normal
creatinine clearance > 60 mL/min for patients with creatinine levels above institutional normal
Serum creatinine levels =< 1.5 x upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine less than the institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Serum creatinine =< 1.5 × upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Within 14 days after subjects signed the treatment consent: Serum creatinine =< 1.5 mg/dl OR creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine ? 2.0 mg/dl Or Creatinine clearance ? 60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal
Creatinine less than institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above the institutional normal
Creatinine < 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels >= 1.5 x upper limit of normal
Creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min for subjects with creatinine levels about institutional normal
EXPANSION COHORT ONLY: Creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min for subjects with creatinine levels about institutional normal
Creatinine =< institutional ULN or creatinine clearance >= 30 mL/min/1.73 m^2 for subjects with creatinine levels above institutional ULN
Creatinine =< the institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 x institutional upper limit of normal
Creatinine < 1.5 x upper limit of normal OR measured creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x upper limit of normal
Serum creatinine =< 1.5 x upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance > 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
creatinine clearance* >45 mL/min/1.73 m2 for patients with creatinine levels above institutional normal
Creatinine =< 1.2 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine above institutional normal
Creatinine =< 1.5 x institutional ULN or creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, obtained through calculated or measured creatinine clearance
Creatinine within normal institutional limit for the reference lab OR creatinine clearance >= 60 mL/min/1.73 m^2 as calculated by Cockcroft-Gault formula for participants with creatinine levels above institutional normal
Creatinine within 1.5 x upper limit of normal OR creatinine clearance > 60 mL/min for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 X upper normal limit of institution's normal range OR creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine not to be above IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < institutional upper limit of normal (ULN) OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels greater than ULN
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x upper limit of normal or creatinine clearance >= 60ml/min for patients with creatinine levels above institutional normal
Creatinine < 1.5 X institution upper limit of normal OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine less than the institutional upper limit of normal OR creatinine clearance >= 50 mL/min/1.73 m^2
Renal: serum creatinine WNL or calculated creatinine clearance ? 50 mL/min/1.73m2 for patients with creatinine levels above institutional normal
Creatinine < 1.5 x institutional upper limit or normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 x institutional upper limit of normal
Creatinine =< institution upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine < 1.5 x ULN or creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< institutional upper limit of normal or creatinine clearance (either estimated or calculated) >= 60 mL/min/1.73 m for patients with creatinine levels above institutional normal
Creatinine below 1.5 X upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine =< 2 X institutional ULN OR creatinine clearance >= 30 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 x ULN OR creatinine clearance >= 60 ml/min for patients with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < 1.5 X institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < 1.5 X institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine level above institutional normal
Creatinine =< 1.5 X institutional upper limit of normal or creatinine clearance less than 60 ml/min
Creatinine < 1.5 x upper limit of normal (ULN) or creatinine clearance >= 50 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< IULN OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance ? 15 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< 2.0 or creatinine clearance > 30 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 30 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine clearance >= 70 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 x institutional upper limit of normal (ULN)
Creatinine clearance >= 50 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 times institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2
Creatinine £ 1.5 ´ ULN or creatinine clearance > 60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal
Creatinine below upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within 1.5 x upper limit of normal (ULN) OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine ? 1.5 mg/dL or creatinine clearance > 60 mL/min/1.73 m2 for subjects with creatinine levels above institutional normal.
Creatinine =< 1.5 X institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine level =< IULN within 28 days prior to registration
Within 28 days prior to registration: Serum creatinine =< 2.0 x IULN
Patients must have adequate renal function with serum creatinine level =< IULN within 21 days prior to registration
Serum creatinine =< 2.0 x IULN within 28 days prior to registration
Patients must have creatinine clearance =< 2.5 x IULN
Patients must have serum creatinine =< 2 x institutional upper limits of normal (IULN) within 7 days prior to registration
Serum creatinine =< 1.5 x the IULN
Creatinine =< 1.5 x IULN OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x IULN (that is, if serum creatinine is > 1.5 x IULN, a 24-hour urine collection to calculate creatinine clearance must be performed)
Creatinine =< IULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with serum creatinine levels above institutional normal (IULN) (calculated by creatinine clearance estimate by Cockcroft-Gault equation)
Serum creatinine =< 1.5 x institutional upper limit of normal (IULN) OR creatinine clearance by Cockcroft-Gault >= 60 mL/min for patients with serum creatinine > 1.5 x IULN
Serum creatinine =< 1.5 x IULN OR creatinine clearance by Cockcroft-Gault >= 30 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x IULN
Adequate renal and hepatic function (creatinine ? 2.0 x IULN, bilirubin ? 1.5 IULN, AST and ALT ? 3.0 x IULN or 5 x IULN if known liver metastases).
Serum creatinine =< 1.5 x IULN OR creatinine clearance by Cockcroft-Gault >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x IULN
Serum creatinine =< 1.5 x IULN OR creatinine clearance by Cockcroft-Gault >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x IULN
Serum creatinine < 3 x IULN
Adequate renal and hepatic function (creatinine ? 1.5 x IULN, bilirubin ? IULN, AST and ALT ? 3.0 x IULN or 5 x IULN if know liver metastases).
Creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 50 mL/min for patients with creatinine levels > 1.5 x IULN
Adequate renal and hepatic function (creatinine ? 1.5 x IULN, bilirubin within normal limits, AST and ALT ? 3.0 x IULN or 5 x IULN if know liver metastases)
Creatinine =< 1.5 x IULN
Within 14 days of subject registration: Serum creatinine =< 1.5 X IULN
Baseline BNP > 2 x IULN
Serum creatinine =< 1.5 x IULN
Serum creatinine =< 2 x institutional upper limit of normal (IULN), unless due to lymphoma, within 42 day prior to registration
Performed within 14 days of patient registration: Serum creatinine =< 1.5 x IULN
Serum creatinine =< IULN within 14 days prior to registration
Serum creatinine =< 1.5 x IULN within 14 days prior to Step 2 Randomization OR
Serum creatinine =< 1.5 x IULN within 14 days prior to Step 3 registration OR
Baseline troponin I or T > IULN and b-type natriuretic peptide > IULN
Serum creatinine level =< IULN
Serum creatinine =< 1.5 x IULN (assessed within 7 days prior to study day 1)
Serum creatinine =< 1.5 x IULN OR creatinine clearance by Cockcroft-Gault >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x IULN
Serum creatinine < 2.0 x IULN within 28 days prior to registration
Serum creatinine =< 2.0 x IULN
Serum creatinine =< 1.5 x IULN obtained within 28 days prior to registration
Transaminases =< IULN
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal (using Cockcroft Gault formula)
Acceptable renal function: o Serum creatinine within normal limits, OR calculated creatinine clearance 60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal.
Creatinine =< 1.5 x above institutional normal or >= 60 ml/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance > 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (using Cockcroft-Gault formula)
Creatinine within institutional normal limits (WNL) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance ? 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Obtained within 21 days prior to study registration: creatinine within normal institutional limits OR creatinine clearance ? 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or creatinine clearance >= 40 ml/min
Creatinine =< upper limit of normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits, OR creatinine clearance >= 60 mL/min, based either on Cockcroft-Gault estimate or based on urine collection (12 or 24 hour), for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance ? 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 times normal institutional limits OR creatinine clearance >= 40 ml/min for patients
Creatinine =<1.5 x normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine up to 1.5 upper institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal 14 days or fewer from registration
Creatinine within normal institutional limits or creatinine clearance (estimated glomerular filtration rate [eGFR]) >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine levels within normal institutional limits; or, creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal; unless decreased due to renal involvement by lymphoma
Serum creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or creatinine clearance > 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine =< 2 x normal institutional limits OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal as defined by the Cockcroft-Gault equation
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits; OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Serum creatinine within normal institutional limits OR measured creatinine clearance >= 50 mL/min/for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine 1.5 x the normal institutional limits OR creatinine clearance >= 40 mL/min/1.73 m^2
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/ per Cockroft-Gault equation\r\nfor patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine not greater than upper institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 45 mL/min/1.73 m^2 as estimated by either Cockcroft-Gault or 24-hour urine collection for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limits of normal OR creatinine clearance of >= 50 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal by 24-hour urine
Creatinine within normal institutional limits OR creatinine clearance > 50 mL/min for patients with creatinine levels above institutional normal
PHASE I STUDY ELIGIBILITY CRITERIA:\r\nCreatinine =< 1.5 X within normal institutional limits OR measured creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, determined within 14 days of registration
Creatinine within normal institutional limits OR creatinine clearance > 45 mL/min for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits (< 1.5) OR creatinine clearance >= 50 mL/min/1.73m^2 (for creatinine level above normal)
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine < 1.5x institutional upper limits of normal (ULN) or creatinine clearance ? 60 mL/(min 1.73 m^2) for patients with elevated creatinine levels (? 21d of study day 1)
Creatinine clearance > 50 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal limits
EXCLUSION CRITERIA FOR TREATMENT: Creatinine clearance > 50 ml/min/1.73m^2 for patients with creatinine levels above institutional normal limits
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR calculated creatinine clearance >= 60 mL/min/1.73 m^2 (Cockroft-Gault formula) for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR calculated creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or creatinine clearance must be at least 60 ml/min
Creatinine < 1.5 x normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine level above institutional normal based either on Cockroft-Gault estimate or based on urine collection (12 or 24 hour)
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or a creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or a creatinine clearance >= 60 ml/min within 2 weeks prior to registration
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits for age OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above ULN
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional limits
Creatinine within normal limits (creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal)
Obtained within 30 days of registration: Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits, OR creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits, or creatinine clearance (calculated by Cockcroft-Gault) >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits for age OR creatinine clearance >= 70 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within institutional limits of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal obtained =<14 days prior to randomization
Serum creatinine within normal institutional limits or creatinine clearance at least 60 ml/min within 30 days prior to registration
Serum creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 40 mL/min for patients with creatinine levels above institutional normal
Creatinine within 1.5 X normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal by Cockcroft-Gault equation
Patients must have normal organ and marrow function as defined below: leukocytes ?3,000/mcL, absolute neutrophil count ?1,500/mcL, platelets ?100,000/mcL, total bilirubin within normal institutional limits, aspartate aminotransferase AST(SGOT)/ alanine aminotransferase ALT(SGPT) ?2.5 X institutional upper limit of normal, creatinine within normal institutional limits OR creatinine clearance ?60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal.
REGISTRATION INCLUSION CRITERIA: Creatinine =< 1.5 institutional upper limits of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limits of normal OR creatinine clearance of >= 50 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal by 24 hour urine
Creatinine within normal institutional limits OR creatinine clearance >= 50mL/min for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x normal institutional limits or creatinine clearance > 50mL/min
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with serum creatinine < 2 mg/mL
Creatinine below or within the upper institutional limits of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 X normal institutional limits or creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above normal institutional limit (a calculated one may be used)
Creatinine OR creatinine clearance within normal institutional limits OR > 60 Ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (as calculated by Cockcroft-Gault)
Creatinine within normal institutional limits or creatinine clearance >= 60mL/min/1.73 m^2 for subject with creatinine levels above institutional normal
Creatinine within normal institutional limits OR calculated creatinine clearance >= 60 mL/min/1.73 m^2 for patients with levels above institutional normal using modified Cockcroft-Gault
Creatinine:\r\n* Creatinine levels within normal institutional limits (< 1.5 x ULN); or,\r\n* Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x institutional upper limits of normal OR creatinine clearance > 50 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal, as determined by a measured 24-hour creatinine clearance
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (unless due to lymphoma)
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal
Creatinine =< 1.5 x upper normal limits OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, as calculated by the Cockcroft Gault formula
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within institutional limits of normal or creatinine clearance >= 60 ml/min/m^2 if elevated creatinine
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance or calculated >= 60 mL/min/1.73 m^2 for patients with creatinine clearance or estimated creatinine levels above institutional glomerular filtration rate (eGFR) normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine less than upper limit of normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine within normal institutional limits or less than the lower limit of normal institutional limits; or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 if serum creatinine > institutional normal
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 55 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 30 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal; (calculated via Cockcroft-Gault equation)
SURGICAL ARM: creatinine within normal institutional limits or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels about institutional normal limit
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits or\r\n* Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Subject must have adequate renal function with creatinine within normal institutional limits or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels above institutional normal
Creatinine within normal institutional limits or creatinine clearance ? 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (calculated via Cockcroft-Gault equation)
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Creatinine within normal institutional limits OR creatinine clearance >= 30 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (calculated via Cockcroft-Gault equation)
Creatinine within normal institutional limits or creatinine clearance > 60 mL/min/1.73 m2 for subjects with creatinine levels above institutional normal.
Creatinine within normal institutional limits or creatinine clearance > 60 mL/min/1.73 m2 for subjects with creatinine levels above institutional normal.
Creatinine =< 2.0 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min using the lean body mass formula only
Creatinine =< upper limit of normal (ULN) or calculated creatinine clearance >= 60 mL/min
Creatinine =< institutional upper limit normal (ULN), CTCAE v 3.0 grade 0; NOTE: if creatinine > ULN, creatinine clearance must be > 50 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) mg/dL OR calculated (calc.) creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 40 mL/min, within 4 weeks of randomization
Creatinine =< 1.5 times institutional upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min
Adequate renal function defined as creatinine less than or equal to 1.5 X ULN (upper limit of normal) or calculated creatinine clearance greater than or equal to 40 mL/min per the Cockcroft and Gault formula with creatinine levels greater than 1.5 X ULN
creatinine clearance ?60 mL/min/1.73 m2 for subjects with serum creatinine levels >1.5 × higher than ULN.
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
Measured within 28 days prior to registration: serum or plasma creatinine =< 1.5 x institutional upper limit of normal (ULN) OR creatinine clearance >= 51 mL/min/1.73 m^2 for participants
Creatinine > 1.5 times ULN concurrent with creatinine clearance < 50 ml/min; confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Serum creatinine =< 1.5 x institution's upper limit of normal (ULN), or creatinine clearance >= 30 ml/min (according to Cockroft-Gault formula, or local institutional standard method)
Creatinine =< 1.5 x the institutional upper limit of normal (ULN), or 24-hr clearance >= 50 mL/min, within 14 days of registration
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 50 mL/min
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Serum creatinine or creatinine clearance =< institutional upper limit or >= 60 mL/min creatinine clearance for patients with serum creatinine > institutional upper limit
Serum creatinine =< 1.5 x upper limit of normal or calculated creatinine clearance >= 60 mL/min using Cockcroft-Gault equation for patients with creatinine levels > 1.5 x institutional upper limit of normal (ULN)
Serum creatinine =< 1.5 x institutional upper limit of normal (ULN) OR calculated creatinine clearance >= 50 mL/min for subjects with creatinine levels > 1.5 x institutional ULN within 28 days of treatment initiation and must be independent of hematopoietic growth factor support
Creatinine clearance < 1.5 x institutional ULN
Serum creatinine < 2.0 x ULN or creatinine clearance > 30 cc/min performed within 30 days prior to the date of registration
Creatinine within the institution's laboratory upper limit of normal (ULN) or calculated creatinine clearance >50 ml/min
Creatinine > 1.5 times the ULN concurrent with creatinine clearance < 50 mL/min (measured or calculated by the Cockcroft - Gault equation); confirmation of creatinine clearance is only required when creatinine is > 1.5 times the ULN.
Patient may not have severe renal disease (creatinine greater than 3 times normal for age OR creatinine clearance < 50 ml/m^2/1.73 m^2)
Serum creatinine ?1.5 × institutional upper limit of normal (ULN) or calculated creatinine clearance >30 mL/min.
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 30 mL/min for subject with creatinine levels > 1.5 x institutional ULN
Creatinine =< 1.5 x upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN (obtained =< 14 days prior to registration)
Either creatinine < 1.5 x institutional upper limit of normal (ULN) or creatinine clearance > 60 mL/min as calculated by institution’s standard formula
Creatinine < 1.5 x ULN OR creatinine clearance > 50 mL/min for subject with creatinine levels > 1.5 x ULN
COHORT 1: HORMONE RECEPTOR POSITIVE BREAST CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
COHORT 2: TRIPLE NEGATIVE BREAST CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
COHORT 3: ENDOMETRIAL CANCER: Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min for subject with creatinine ? 1.5 x institutional ULN obtained =< 14 days prior to registration
Creatinine OR calculated creatinine clearance =< 1.5 x upper limit of normal (ULN) OR >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN. Creatinine clearance should be calculated per institutional standard.
Serum creatinine < 2 x upper limit of normal (ULN) or estimated creatinine clearance > 30 ml/min as calculated using the method standard for the institution
Obtained =< 14 days prior to registration: Creatinine =< 1.5 X upper limit of normal (ULN)\r\n* NOTE: measured or calculated (per institutional standard) creatinine clearance is acceptable >= 60 mL/min for subject with creatinine levels > 1.5 X institutional ULN
Creatinine =< 2.0 x the institutional upper limit of normal (ULN) OR creatinine clearance > 30 ml/min within 14 days of cycle 1 day 1
Cockcroft calculated creatinine clearance of >= 45 ml/min or 1.5 x the upper limit of normal (ULN)
Serum creatinine =< 1.5 x age-adjusted upper limit of normal (ULN) or calculated creatinine clearance (Cockcroft and Gault) > 30 mL/min/1.73 m^2
Creatinine =< 1.5 ULN OR creatinine clearance >= 60 Ml/min/1.73 m^2 for patients with creatinine levels above ULN calculated using Calvert formula
Serum creatinine =< 2 x upper limit of normal (ULN) or estimated creatinine clearance >= 15 mL/min as calculated using the method standard for the institution
Serum creatinine >= 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance =< 30 mL/min for patients with creatinine levels > 1.5 x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard
Serum creatinine =< 1.5 x institution’s upper limit of normal (ULN), or creatinine clearance >= 60 ml/min
Serum creatinine > 1.5 x upper limit of normal (ULN) or creatinine clearance < 40 mL/min (measured or calculated by Cockroft-Gault formula)
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min for subject with creatinine ? 1.5 x institutional ULN obtained =< 14 days prior to registration
Creatinine level =< upper limit of normal (ULN): if creatinine > ULN, creatinine clearance must be > 60 ml/min
Serum creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min/1.73 m^2)
Adequate renal function defined as: • Serum creatinine ? 1.5 x ULN (upper normal limit) or calculated creatinine clearance (determined by MDRD) > 50 mL/min/1.73m2.
Serum creatinine =< upper limit of normal (ULN) for the lab or a calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 50 mL/min for patient with creatinine levels > 1.5 x institutional ULN
Serum creatinine =< 1.5 X upper limit of normal (ULN), or measured creatinine clearance >= 60 mL/min/1.73 m^2
Creatinine less than or equal to 1.5 x upper limit of normal (ULN) with calculated creatinine clearance greater than 30 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 60 mL/min for subjects with creatinine levels > 1.5 x ULN within 14 days of treatment initiation
Creatinine =< 2.0 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above 2.0 x ULN
Serum creatinine < 2.0 times the upper limit of normal (ULN) (or a calculated creatinine clearance >= 60 mL/min)
Creatinine > 1.5 times ULN concurrent with creatinine clearance < 30 ml/min (measured or calculated by Cockcroft and Gault equation); confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Creatinine clearance >= 40 ml/min or serum creatinine =< 2.5 x upper limit of normal (ULN)
Serum creatinine >= ULN and/or calculated or measured creatinine clearance < 75% lower limit of normal (LLN)
Creatinine =< 2.0 x upper limit normal (ULN) or measured creatinine clearance (CrCl) of >= 50ml/m^2/1.73 m^2
Creatinine =< 1.5 x the upper limit of normal (ULN) OR \r\n* Estimated creatinine clearance of > 50 ml/min\r\n* Patients with renal dysfunction deemed to be the result of disease will be considered eligible
Creatinine clearance >= 60 mL/min/1.73m^2 for patients with creatinine >= 1.5 x upper limit of normal
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
CAPMATINIB INCLUSION CRITERIA: Creatinine OR creatinine clearance within normal limits > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
REGORAFENIB INCLUSION CRITERIA: Creatinine OR creatinine clearance =< 1.5 x ULN; > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
ENTRECTINIB INCLUSION CRITERIA: Creatinine OR creatinine clearance within normal limits; > 40 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
Serum creatinine =< 1.25 times upper limit of normal or calculated creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 X ULN OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 X institutional ULN
Calculated creatinine clearance ? 60 mL/min /1.73 m2 for subjects with serum creatinine levels > 1.5 x institutional ULN
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= 60 mL/min
Serum creatinine >1.5 x ULN and/or measured or calculated creatinine clearance <75% LLN
Biochemistry: Total bilirubin* ? institutional upper limit of normal Alkaline phosphatase ? 2.5 x institutional upper limit of normal AST(SGOT) and ALT(SGPT) ? 2.5 x institutional upper limit of normal Creatinine Clearance ? 40 ml/min * excluding Gilbert's syndrome Creatinine clearance to be measured directly by 24 hour urine sampling or as calculated by Cockcroft Formula: Females: GFR = 1.04 x (140-age) x weight in kg serum creatinine in ?mol/L Males: GFR = 1.23 x (140-age) x weight in kg serum creatinine in ?mol/L
Serum creatinine < 1.5 times upper limit of normal range (ULN) or creatinine clearance >= 40 ml/min
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance of >= 50ml/min
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 x institutional ULN
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for patients with creatinine levels > 1.5 x institutional ULN\r\n* Creatinine clearance should be calculated per institutional standard
Serum creatinine =< 1.5 X upper limit of normal (ULN) or creatinine clearance > 50 mL/min
Serum creatinine > 1.5 times ULN concurrent with creatinine clearance < 50 mL/min (measured or calculated by Cockcroft and Gault equation)—confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
Adequate renal function (creatinine =< 1.25 upper limit of institutional normal [ULIN] or calculated creatinine clearance > 50 ml/min)
Serum creatinine =< 2 x the institutional ULN and measured or estimated creatinine clearance > 60 cc/min
The patient must have a corrected creatinine clearance >= 50% of normal
Serum creatinine =< 1.5 x institutional upper limit normal (ULN) and calculated creatinine clearance of >= 60mL/min
Creatinine ?1.5 times the upper limit of normal (ULN) and/or creatinine clearance ?60 mL/min
REGISTRATION TO TREATMENT (STEP 1): Serum creatinine =< 1.5 X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= 60 mL/min for patient with creatinine levels > 1.5 X ULN, within 14 days prior to first dose of pembrolizumab
REGISTRATION TO TREATMENT (STEP 2): Serum creatinine =< 1.5 X upper limit of normal (ULN) OR creatinine clearance (per institutional standards) >= 60 mL/min for patient with creatinine levels > 1.5 X ULN, within 14 days prior to first dose of pembrolizumab
Creatinine =< 1.5 x upper limit of normal (ULN) OR >= 60 mL/min
Within 10 days of treatment initiation: If serum creatinine concentration >= 1.5 x upper limit of normal (ULN), then estimated creatinine clearance must be >= 60 mL/min for subject with creatinine levels > 1.5 x institutional ULN
Creatinine or measured/calculated creatinine clearance (as calculated by institutional standard) =< 1.5 X institutional upper limit of normal (ULN) OR >= 60 mL/min for subjects with creatinine levels > 1.5 x institutional ULN
Serum creatinine value < upper limit of normal (ULN) or creatinine clearance of >= 60 mL/min according to Cockgroft?Gault formula
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine OR =< 1.5 mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance >= 60 mL/min
Patients must have a serum creatinine limit of =< 1.5 ULN or creatinine clearance of >= 60 ml/min measured within 14 days of registration
Creatinine < 1.5 x ULN OR creatinine clearance measured >= 60 mL/minute for patients with creatinine levels >= 1.5 x upper limit of normal
Creatinine =< 1.5 x upper limit of normal (ULN) for the laboratory or calculated or actual creatinine clearance > 45 mL/min
Serum creatinine =< 1.5 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% LLN (lower limit of normal)
Creatinine =< 1.5 times the upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Creatinine =< institutional upper limit normal (ULN); note: if creatinine > ULN, creatinine clearance must be > 50 mL/min
Creatinine =< 1.5 X ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x ULN
PHASE II: Creatinine =< 1.5 X ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 x ULN
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 2.0 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 30 mL/min obtained within 28 days prior to registration
Serum creatinine =< ULN within 14 days prior to registration OR calculated creatinine clearance > 50 ml/min; the serum creatinine value used in the calculation must have been obtained within 14 days prior to registration
Creatinine =< 1.5 x ULN OR calculated or measured creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine above institutional normal
Serum creatinine =< 1.5 X upper limit of normal (ULN) OR measured or calculated creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 X institutional ULN
Creatinine =< 1.5 mg/dL x upper limits of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
Creatinine > 1.5 x the upper limit of normal; patients with creatinine > 1.5 x the upper limit of normal who have creatinine clearance >= 60 cc/min (calculated using the Cockcroft and Gault equation) are eligible
Serum creatinine =< 1.5 x upper limit of normal (ULN) for the lab, calculated creatinine clearance >= 60 mL/min or 24-hour creatinine clearance >= 50 mL/min
Serum creatinine ?1.5 times institutional ULN or calculated creatinine clearance >30 mL/min;
Serum creatinine =< 1.5 x institutional upper limit of normal concurrent with creatinine clearance >= 50 mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > 1.5 x upper limit of normal (ULN), within 14 days of study registration
Within 72 h of initiating study treatment: Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min for subject with creatinine levels > 1.5 x ULN (Cockcroft and Gault)
Creatinine =< ULN or a calculated creatinine clearance of >= 45 ml/min if creatinine is greater than the ULN
Serum creatinine performed within 4 weeks prior to study entry must be less than or equal to 1.25 x ULN or estimated creatinine clearance less than 60 mL/min (as calculated using the method standard for the institutions).
Patients must have adequate renal function, defined as serum creatinine ? 1.5 x ULN or creatinine clearance (calculated) ? 60 mL/min/1.73 m2 for patients with creatinine > 1.5 x ULN.
Creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance >= 30 mL/min (Cockcroft-Gault calculation)
Creatinine <1.5 X upper limit of normal or estimated plasma creatinine clearance of ?40 mL/min
At least 4 weeks (28 days) prior to registration: Serum creatinine =< 1.5 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% LLN (lower limit of normal)
Serum creatinine ? 1.5 × age-adjusted upper limit of normal (ULN) OR calculated creatinine clearance > 30 mL/min
Serum creatinine =< upper limit of normal (ULN) or creatinine clearance (either estimated or calculated) >= 60 mL/min/1.73 m for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 × the institutional ULN; if creatinine is above the ULN, the patient's measured or calculated creatinine clearance (CrCl) must be >= 50 mL/min
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73m^2 for patients with creatinine >= 1.5 x upper limit of normal
Serum creatinine =< 1.5 x upper limit of normal OR calculated creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance >= 40 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 x the upper limit of normal or creatinine clearance >= 60 mL/min (measured or calculated)
Serum creatinine =< 1.5 x the upper limit of normal or calculated creatinine clearance >= 60 mL/min
Serum creatinine clearance =< 1.5 x ULN or >= 60 mL/minute for subjects with creatinine levels > 1.5 x the institutional upper limit of normal (ULN)
Serum creatinine ? 1.5 × ULN according to institutional standards or creatinine clearance ? 50 mL/min
Serum creatinine ?1.5 x upper limit of normal (ULN) or a calculated creatinine clearance >60 mL/min,
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 2 x the institutional ULN and measured or estimated creatinine clearance >= 50 cc/min
Serum creatinine <1.5 x upper limit of normal (ULN) or estimated creatinine clearance 60 mL/min (as calculated using the standard method of the institution);
Patient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.
Adequate renal function defined as serum creatinine ? 1.5x upper limit of normal (ULN) for age. If the serum creatinine is above these values, the calculated creatinine clearance or radioisotope GFR must be ? 70 mL/min/1.73m2.
Creatinine =< 1.5 x upper limit of normal (ULN); either lab result or calculated clearance
Serum creatinine > 1.5 x ULN and/or measured or calculated creatinine clearance < 75% LLN (lower limit of normal) Bone marrow function:
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 mL/min (please use institutional formula)
Serum creatinine < 1.5 x ULN or creatinine clearance ? 60 mL/min as measured by institutional standards
Calculated creatinine clearance (CrCl) of greater than or equal to 50 or serum creatinine less than 2 x ULN; even if organ function abnormalities are considered due to tumor, the upper limit for creatinine is less than or equal to 2 mg/dL
Acceptable renal function: • Serum creatinine ? 1.5 times the ULN, or calculated creatinine clearance ? 60 mL/min/1.73 m2 for patients with creatinine levels above 1.5 times the institutional normal
Creatinine > 2.0 times upper normal limit and creatinine clearance < 30 ml/min/m^2; patients with creatinine > 2 times upper limit of normal will have creatinine clearance estimated; at the discretion of treating physician, creatinine clearance can be measured and that value can be used instead of calculated creatinine clearance
Creatinine =< 1.5 x laboratory upper limit of normal or calculated creatinine clearance of >= 50 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN), or, calculated creatinine clearance (CrCl) >= 50 mL/min
Creatinine =< 1.5 x upper limits of normal (ULN); if creatinine (Cr.) > 1.5 x ULN, then calculated creatinine clearance > 40 cc/min
Serum Creatinine < 1.5 x ULN (upper limit of normal) or estimated creatinine clearance ? 60 mL/min, as calculated using method standard for the institution (Appendix 2).
Patient's serum creatinine must be ? 1.5 x institutional upper limit of normal (ULN) according to age. If the serum creatinine is greater than 1.5 times normal, the patient must have a calculated creatinine clearance or radioisotope GRF ? 70mL/min/1.73m2.
Creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance >= 60 ml for patients with creatinine levels 1.5 times above institutional ULN (calculated based on age, weight and sex)
Creatinine < 1.5 times the upper limit of normal (ULN) or creatinine clearance > 40 mL/min (as measured or calculated by Cockroft-Gault formula)
Serum creatinine ? 1.5 x upper limit of normal (ULN) or calculated creatinine clearance > 60 mL/min if the serum creatinine is > 1.5 x ULN
Serum creatinine >= 1.5 times the upper normal limit or calculated/measured creatinine clearance =< 60 mL/min
Creatinine < 2.0 x upper limit of normal and/or a creatinine clearance >= 60 ml/min
Serum creatinine > 1.5 x upper limit of normal (ULN); if creatinine 1.0-1.5 x ULN, creatinine clearance, calculated according to Cockcroft-Gault formula, < 60 ml/min will exclude the patient
Creatinine =< 1.5 x ULN OR calculated or measured creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine above institutional normal
Patients must have adequate renal function, defined as serum creatinine <= 1.5 x upper limit of normal (ULN) for the institution or a calculated creatinine clearance [Cockcroft-Gault method] must be >= 60 mL/min/1.73 m^2).
Kidney disease with a calculated creatinine clearance <30% normal value.
Creatinine < 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance >= 50 cc/min
Serum creatinine ? 1.5 × upper limit of normal (ULN) or calculated creatinine clearance ? 50 mL/min using Cockcroft-Gault equation for patients with creatinine levels > 1.5× institutional ULN
Serum creatinine ?1.5 x ULN or creatinine clearance > 60 mL/min/1.73 m^2 for subjects with creatinine levels >1.5 x ULN
Serum creatinine less than 1.5 x upper limit of normal (ULN), OR 24-hour creatinine clearance = or 60 mL/min for subject with creatinine levels more than 1.5 x ULN; (Note: creatinine clearance need not be determined if the\r\nbaseline serum creatinine is within normal limits; creatinine clearance should be determined per institutional standard)
Creatinine value of =< 1.5 x upper limit of normal (ULN) or creatinine clearance value of >= 40 mL/min
Creatinine ? 1.5 x upper limit of normal (ULN) of institution's range or Creatinine clearance ? 50%
Serum creatinine < 1.5 x upper limit of normal (ULN) or a calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x institutional upper limit of normal concurrent with creatinine clearance >= 50 mL/min (measured or calculated by Cockcroft and Gault equation), confirmation of creatinine clearance is only required when creatinine is > 1.5 x upper limit of normal (ULN) (within 14 days of study registration)
Serum creatinine =< 4.0 x ULN or calculated or directly measured creatinine clearance (CrCl) >= 50% of LLN (lower limit of normal)
Have adequate renal function, defined as serum creatinine levels ?2.0 ULN or calculated creatinine clearance >45 mL/min.
Serum creatinine =< 1.5 x institutional ULN or 24-hour clearance >= 50 mL/min
Serum creatinine < 1.5 x upper limit of normal (ULN) or 24-hour creatinine clearance > 50 ml/min
Serum creatinine =< 2.0 x institution’s ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 x ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 mg/dL or 24-hour clearance >= 50 mL/min
Obtained =< 7 days prior to registration: Serum creatinine =< 2 x ULN or 24 hour creatinine (Cr) clearance > 60 ml/min
Serum creatinine =< 1.5 x institutional ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN, or 24-hr clearance >= 60 ml/min, within 14 days start of study start
Serum creatinine =< 2 x ULN or 24 hour creatinine (Cr) clearance > 30 ml/min obtained =< 7 days prior to registration
Creatinine less than 1.5 x ULN, or a 24 hour creatinine clearance of 60 mg/mL or more
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 ml/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 ml/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine ? 1.5 x ULN, or 24-hour (hr) clearance ? 60 ml/min
Within 14 days prior to registration: Serum creatinine =< 1.5 x institution’s ULN or calculated 24-hour creatinine clearance >= 50 mL/min
Serum creatinine < 1.5 x ULN or serum creatinine clearance > 50mL/min
Serum creatinine < 2 x the institutional ULN; however, if serum creatinine > 1.5 x ULN, a 24 hour urine creatinine clearance must be > 50 ml/min unless there is renal involvement by lymphoma
Serum creatinine ? 1.5 x ULN, or 24-hr clearance ? 60 mL/min,
Within 14 days of study start: Serum creatinine =< 1.5 x ULN, or 24-hr clearance >= 60 ml/min; and
Serum creatinine =< 1.5 x institution’s ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine =< 2 x ULN or 24-hour creatinine clearance >= 60 ml/min
Serum creatinine =< 1.5 x institution's ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine less than or equal to 1.5 x ULN or 24-hour clearance greater than or equal to 50 mL/min
24-hour (hr) creatinine clearance >= 30 cc/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine less than or equal to 1.5 x ULN or 24-hour clearance greater than or equal to 50 ml/min
Serum creatinine =< 1.5 x ULN or 24 hour creatinine (Cr) clearance > 50 ml/min
Serum creatinine =< 1.5 x institutional ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 ml/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 ml/min
Serum creatinine =< 1.5 x institution's ULN or 24-hour creatinine clearance >= 50 ml/min
The patient has serum creatinine <2×ULN and not rising for at least 2-4 weeks before chemotherapy. If elevated, the 24-hour creatinine clearance must be >50 mL/min
Serum creatinine =< 1.5 X ULN OR 24-hour creatinine clearance >= 60 mL/min
Serum creatinine (Cr) =< 2 x ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN, or 24-hour (hr) clearance >= 60 ml/min
Serum creatinine =< 1.5 x ULN (or 24-hour creatinine clearance >= 50 ml/min)
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN or 24-hour creatinine clearance >= 50 ml/min
Serum creatinine =< 1.5 X ULN or 24-hour clearance >= 55 mL/min
Serum creatinine (CR) < 1.5mg/dl or 24 hour CR clearance < 50 ml/min
Serum creatinine =< 1.5 x institutional ULN or calculated or measured 24-hour clearance >= 50 mL/min
Renal: Serum/plasma creatinine (sCr) ?1.5 x upper limit of normal, or creatinine clearance (Ccr) ?50 mL/min.
C. Renal: Serum creatinine (sCr) ? 1.5 x upper limit of normal.
Serum creatinine (sCr) =< 1.5 x ULN, or creatinine clearance (Ccr) >= 40 mL/min as calculated by the modified Cockcroft-Gault formula
Renal: Serum creatinine (sCr) ? 2.0 x upper limit of normal.
Renal: serum creatinine (sCr) ?2.0 x ULN, or creatinine clearance (Ccr) ?30 mL/min.
Renal: Serum creatinine (sCr) ?1.5 x upper limit of normal, or creatinine clearance (Ccr) ?50 mL/min.
Renal clearance CCR < 40 mL/min
Renal: serum creatinine (sCr) ?2.0 x ULN, or creatinine clearance (Ccr) ?30 mL/min.
Serum creatinine (sCr) ? 1.5 x ULN;