Adequate hematologic function
Adequate hematologic function
Acceptable liver, renal, hematologic and coagulation function
Adequate hematologic, renal, and liver function
The patient has adequate baseline hematologic function, as demonstrated by the following:
Acceptable hematologic, renal and liver function as follows:
Adequate hematologic status
Adequate organ function, hematologic status, coagulation status, kidney function, and liver function as follows:
Adequate hematologic function
Hematologic (BM Function):
Adequate hematologic function (unless abnormalities are related to NHL), defined as follows:
Subject has adequate hematologic function and adequate hepatic function at screening
Participant must have adequate hematologic, renal, and liver function laboratory values as described in the protocol.
Hematologic (BM Function):
Adequate kidney and hematologic function assessed from baseline laboratory data
Have adequate hematologic function.
Adequate hematologic function:
Adequate hematologic function
Adequate hematologic function
Adequate hematologic function
Inclusion Criteria:\n\n        Patients with histologically or cytologically confirmed advanced solid malignancy or\n        Lymphoma\n\n        Relapsed or refractory disease after at least 1 prior systemic treatment for the primary\n        malignancy and not a candidate for other curative treatment.\n\n        Adequate hematologic status\n\n        Adequate coagulation function\n\n        Adequate hepatic function\n\n        Adequate renal function\n\n        Exclusion Criteria:\n\n        Known primary tumors of central nervous system disease\n\n        Known active brain metastases\n\n        Known cardiopulmonary disease
Adequate hematologic function:
Adequate renal, and hematologic function
Adequate hematologic function
Adequate baseline hematologic function, as demonstrated by the following:
Adequate hematologic status
Adequate hematologic function:
Adequate hematologic function as defined by:
Adequate hematologic, renal and liver function
Adequate hematologic function
Must have adequate hematologic, renal, and liver function
Patients must be suitable candidates for treatment with standard regimens; this includes having adequate hematologic parameters, liver function and renal function based on labs that are deemed acceptable for treatment by the investigators
Adequate hematologic function, as defined by the following criteria:
Adequate hematologic function.
Adequate hematologic function:
Adequate hematologic function defined by:
Adequate hematologic function
Adequate hematologic, liver, coagulation, renal, and cardiovascular function
Hematologic function, as follows:
Adequate hematologic, renal and liver function
Adequate hematologic, liver, and renal function
Hematologic, liver, and renal function as specified in the study protocol.
Has adequate hematologic, liver, and renal function
Adequate hematologic and renal function as determined by laboratory blood and urine tests
Adequate hematologic function.
Adequate hematologic function as indicated by:
Adequate hematologic, immunologic, liver and renal function, defined as
Adequate hepatic and renal function
Must have adequate hepatic, renal, cardiac and hematopoietic function
Insufficient hepatic and renal function.
Adequate renal and hepatic function
Hepatic and renal function
Adequate renal and hepatic function:
Adequate renal and hepatic function, per laboratory reference range at screening
Adequate renal, hepatic, pulmonary and cardiac function defined as:
Renal function and Hepatic function
Adequate renal and hepatic function as defined:
Adequate organ function, including renal and hepatic function based on the last assessment performed within the Screening Period Patients enrolled in the Dose Finding Portion of the Study:
Adequate renal, hepatic, cardiac, and pulmonary function as evidenced by:
DONOR: Cardiac, renal, pulmonary, and hepatic function within normal limits
Adequate renal and hepatic function:
Adequate hepatic and renal function
Adequate renal and hepatic function:
Adequate hematopoietic capacity, hepatic and renal function
Has protocol-defined adequate renal, hepatic and cardiac status
Adequate renal and hepatic function:
Adequate hepatic and renal function (these must be WNL or verified by study chair to be related to conditions not interfering with normal health status)
Adequate baseline renal and hepatic function
Adequate hepatic and renal function defined as:
The patient has adequate baseline organ function, including cardiac, renal, and hepatic function:
The patient has adequate baseline organ function, including cardiac, renal, and hepatic function:
Has protocol-defined adequate cardiac, renal and hepatic function
Adequate renal and hepatic function defined as:
Adequate hepatic, and renal function
Adequate Blood, renal and hepatic function, as determined within 28 days from registration:
Adequate renal and hepatic function
Adequate hepatic and renal function
Adequate renal, hepatic and pancreatic function
Adequate hepatic and renal function defined as:
Adequate coagulation, renal and hepatic function
Adequate renal and hepatic function
Adequate renal, hepatic, pulmonary and cardiac function defined as:
Adequate hepatic and renal function:
Seriously limited cardiac, renal, or hepatic function
Subject must have adequate coagulation profile, renal, and hepatic function, per laboratory reference range at Screening
Adequate hepatic, renal and pancreatic function.
Adequate renal and hepatic function
Adequate renal and hepatic function.
Subject must have adequate coagulation, renal, and hepatic function, per laboratory reference range at Screening.
Adequate coagulation, renal and hepatic function
Have adequate blood counts, hepatic and renal function
Subject must have adequate coagulation, renal, and hepatic function, per laboratory reference range at Screening.
Subject must have adequate coagulation, renal, and hepatic function, per laboratory reference range at Screening.
Adequate hepatic and renal function within protocol-defined parameters.
Adequate hepatic and renal function
Adequate baseline renal and hepatic function
Adequate pulmonary, renal, hepatic, and cardiac function
Adequate baseline renal and hepatic function
Adequate hepatic and renal function defined as:
have adequate hepatic function and renal function
Adequate renal and hepatic function, as defined by the following criteria:
Adequate renal, hepatic, pulmonary and cardiac function defined as:
Adequate baseline renal and hepatic function
Adequate hepatic, renal, and cardiac function
Renal and Hepatic Function
Adequate hepatic and renal function defined as:
Adequate hepatic and renal function:
No prior anticancer therapy for pancreatic cancer •? 18 years of age with a performance status of 0 or 1•Adequate complete blood counts, hepatic function, and renal function
Have renal and hepatic function as defined by:
Renal and Hepatic Function: Patient must have adequate renal and hepatic functions as indicated by the following laboratory values:
Adequate renal and hepatic function
Adequate baseline renal and hepatic function
Adequate renal and hepatic function and hematopoietic capacity
Adequate hepatic and renal function
The patient has adequate organ function, including cardiac, renal, and hepatic function:
Evidence of laboratory abnormalities in standard renal, hepatic, or coagulation function tests
Adequate hepatic and renal function
Adequate hepatic and renal function
adequate renal, hepatic and pancreatic function
Adequate hepatic and renal function defined as:
Adequate hepatic and renal function defined as:
Adequate renal and hepatic function
Have adequate hematopoietic, hepatic, and renal function at a screening visit
Adequate renal, hepatic, cardiac, and pulmonary function as evidenced by:
Has adequate renal and hepatic function
Adequate hematologic, renal, and hepatic parameters
Adequate hematologic parameters unless clearly due to the disease under study
Adequate hematologic, renal and hepatic laboratory parameters
Adequate hematologic parameters without ongoing transfusional support:
Adequate hematologic parameters without ongoing transfusional support:
Adequate hematologic parameters without ongoing transfusional support:
Adequate renal, hepatic, and hematologic functions per protocol-defined laboratory parameters within ? 7 days before treatment initiation.
Adequate hematologic function within protocol-defined parameters.
Subject has the following laboratory parameters at screening: Adequate hematologic function including:
Patient has any of the following hematologic parameters:
Hematologic parameters must be assessed at least 14 days after a prior transfusion, if any
Hematologic parameters defined by:
Inadequate organ or bone marrow function
Inadequate hematologic function as evidenced by any of the following:
Inadequate liver function as evidenced by any of the following:
Inadequate bone marrow function
Inadequate renal function as defined by serum creatinine > 3x normal for age
Inadequate performance status/organ function.
Inadequate performance status/organ function.
Participants with prior Hepatitis B or C infection with inadequate liver function
Impaired hepatic or renal function, inadequate bone marrow reserve or organ function, Cardiac dysfunction
Inadequate liver function at screening as demonstrated by the following:
Inadequate pulmonary function
Inadequate marrow function in cohort 1:
Inadequate marrow function in cohort 2:\r\n* These patients will not have marrow function criteria
Inadequate liver, renal function as defined below for both cohorts:
An inadequate tumor specimen as defined by the local pathologist
Unstable/inadequate cardiac function:
Inadequate washout from prior therapy
Evidence of inadequate renal function (creatinine > 2 g/dL)
Inadequate bone marrow or organ function
Inadequate performance status/ organ function
Inadequate organ function, evidenced by the following laboratory results:
Pregnancy or inadequate contraception.
have inadequate organ function per protocol
Inadequate lung function
Inadequate hepatic function
Inadequate renal function
Inadequate bone marrow function
Inadequate organ function per protocol-specified total bilirubin, AST and ALT, creatinine clearance and alkaline phosphatase.
Inadequate organ function including:
Unstable/inadequate cardiac function:
Inadequate organ function including:
Inadequate organ function including:
Inadequate hematologic function (unless due to underlying lymphoma)
Inadequate organ function
Inadequate hematologic, renal, and liver function (unless due to underlying lymphoma)
Inadequate renal or liver function
Inadequate hematological, liver, renal, cardiac function
Has a history or presence of inadequate liver, renal, hematopoietic and/or cardiac function parameters outside protocol-defined range
Inadequate hematologic function, renal function, and liver function
Subject has inadequate marrow, hepatic, and/or renal function at the Screening Visit defined as:
Inadequate hematologic or hepatic function
Inadequate liver, renal or bone marrow function within 2 weeks of first dose
Inadequate renal function
Inadequate renal function
Inadequate bone marrow, renal, or liver function
Inadequate bone marrow function or evidence of end-organ damage
Inadequate hematologic, renal or liver function
Inadequate organ function as described
Inadequate hematologic, renal or liver function
Inadequate bone marrow, renal, or hepatic function as defined above, or an active coagulopathy that precludes tissue biopsy
E 17. Inadequate organ and bone marrow function
Inadequate liver function at screening and Day 1 (before drug administration) as demonstrated by:
Abnormal/inadequate blood values, liver and kidney function
abnormal/inadequate blood values, liver, and kidney function
Inadequate cardiac function
Inadequate heart function
Inadequate lung function
Inadequate renal, hepatic or bone marrow function
Inadequate renal function (Blood creatinine > 1.5 times the institutional ULN)
Inadequate hematopoietic, liver, endocrine or renal function
Inadequate lung function
Inadequate heart function
Inadequate hematologic or biologic function as determined by the following laboratory tests:
Inadequate organ and bone marrow function as evidenced by:
Inadequate bone marrow or other organ function (excluding hepatic impairment per eligibility criteria).
An inadequate tumor specimen as defined by the central pathologist.
Inadequate organ function as defined on laboratory tests
Inadequate lung function
Inadequate hematologic, biochemical, and organ function
Subject's laboratory results indicate inadequate organ function
Adequate hematological function unless inadequate function is due to underlying disease
Inadequate hematologic, liver, or renal function
Inadequate hematological, biochemical or organ function
Inadequate kidney, liver, blood clotting function
Inadequate blood count
Inadequate hematologic function as evidenced by any of the following:
Inadequate liver function as evidenced by any of the following:
Inadequate housing arrangements
Inadequate hemostasis
Inadequate hepatic function
Inadequate renal function
Inadequate bone marrow function
Adequate hematologic, hepatic, and renal function
Subject must have adequate hematologic, renal and hepatic function.
Participants must have adequate hematologic, renal and hepatic function.
Adequate hepatic, renal, cardiac, and hematologic function
Poor hematologic, renal, or hepatic function
Adequate hematologic, renal, and hepatic function
Adequate hematologic, hepatic, and renal function.
adequate hematologic, renal and hepatic function
Poor hematologic, renal, or hepatic function
Inadequate hematologic, renal or hepatic function.
Adequate hepatic, renal, cardiac, and hematologic function.
Must have adequate hematologic, renal and hepatic function.
Adequate organ function as per Hematologic, Hepatic, Renal and Cardiac Laboratory Values
Adequate hematologic, hepatic, and renal function
Subjects must have adequate hematologic, hepatic and renal function.
Adequate baseline hematologic, renal, and hepatic function
Has adequate hematologic (bone marrow [BM] and coagulation factors), renal and hepatic function as defined by criteria below:
Adequate hematologic, hepatic, and renal function
Adequate baseline hematologic, renal, and hepatic function
Adequate hematologic, coagulation (INR 2-3 max), hepatic and renal function
Inadequate hematologic, coagulation (INR >3), hepatic, renal function
Adequate hematologic, renal and hepatic function
Adequate hepatic, renal, cardiac, and hematologic function
Adequate hematologic, renal, and hepatic function.
Adequate hematologic, hepatic, renal, and coagulation function.
Has adequate hematologic (bone marrow and coagulation factors), renal and hepatic function as defined by criteria below:
Participant must have adequate hematologic, renal, hepatic, and lung function.
Adequate hematologic, renal, and hepatic function (within 28 days of randomization).
Adequate hematologic, renal, and hepatic function
Adequate hematologic, renal, and hepatic function
Adequate hematologic, hepatic, and renal function
Inadequate hematologic, hepatic, or renal function
Has adequate hematologic (bone marrow [BM] and coagulation factors), renal and hepatic function
Adequate hematologic, renal, and hepatic function determined by laboratory blood and urine tests.
Has adequate hematologic (bone marrow and coagulation factors), renal, and hepatic function as defined by criteria below:
Adequate hematologic, hepatic, and renal function
Adequate hematologic, renal and hepatic function, specifically:
Adequate renal, hepatic, and hematologic indices for ipilimumab therapy
Inadequate hematologic, renal, or hepatic function
Adequate hematologic, hepatic, and renal function
Subject has adequate hematologic, hepatic, renal, and coagulation function
Adequate organ function as per pre-defined hematologic, hepatic, renal, and cardiac criteria.
Adequate hepatic, renal, cardiac, and hematologic function
Adequate hepatic, hematologic, and renal function
Adequate hematologic, hepatic, and renal function, defined by:
Adequate hematologic, hepatic, and renal function
Grossly normal pulmonary, cardiac function, renal, hepatic hematologic and performance functions
Adequate hematologic, renal and hepatic function.
Has adequate hematologic, hepatic, and renal function as defined by the protocol
Adequate hematologic, hepatic, renal and cardiac function.
Adequate hematologic, hepatic and renal function
Adequate renal, hepatic, and hematologic indices for ipilimumab therapy
Have adequate hematologic, hepatic, and renal function
Have adequate hematologic, hepatic and renal function
Adequate hematologic, hepatic and renal function.
Adequate hematologic, hepatic, and renal function
Has adequate hematologic, renal, cardiac and hepatic function.
Adequate hematologic, hepatic, and renal function.
Adequate hematologic, hepatic, cardiac, and renal function
Adequate hematologic, hepatic, and renal function.
Not adequate hematologic, renal and hepatic function
Adequate hematologic, renal, and hepatic function.
Adequate hematologic, hepatic, renal function
Poor hematologic, renal, or hepatic function
Adequate hematologic, hepatic, and renal function:
Adequate baseline hematologic, pulmonary, renal, and hepatic function
Adequate hematologic, hepatic and renal function
Adequate hematologic, renal and hepatic function
Adequate hematologic, renal and hepatic function
Subject must have adequate hematologic, renal and hepatic function as follows:
Adequate hematologic, hepatic and renal function
Inadequate hematologic, hepatic or renal function
Adequate hepatic, renal, cardiac and hematologic function
Adequate hematologic, hepatic and renal function as defined by laboratory assessment
Has adequate hematologic, coagulation, hepatic and renal function
Adequate hematologic function, hepatic function, renal function and coagulation function
Participants with adequate hematologic, hepatic, and renal function.
Participant must have adequate hematologic, renal, and hepatic function.
Patient has adequate hematologic, hepatic, and renal function as defined by:
Adequate hepatic, renal, cardiac, and hematologic function
Adequate hematologic, hepatic, and renal function, as evidenced by:
Adequate hematologic, hepatic, and renal function
Adequate hematologic, hepatic, and renal function.