Calculated serum creatinine clearance >= 60 mL/min/1.73 m^2, within 28 days prior to administration of study treatment
Adequate renal function determined within 6 weeks prior to randomization defined as the most recent serum creatinine =< ULN or measured or calculated creatinine clearance > 60 mL/min
STEP I: Calculated creatinine clearance >= 30 mL/min (obtained within 28 days prior to randomization)
Serum creatinine =< 1.5 times ULN OR calculated creatinine clearance >= 70 mL/min
Calculated creatinine clearance > 30 ml/min within 14 days prior to step 2 randomization
Serum creatinine must be =< 2 x the institutional ULN OR creatinine clearance (either measured or calculated) must be > 30 mL/min; must be obtained within 28 days prior to registration
Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min, obtained within 28 days prior to step 2 registration
Within 14 days of registration: Calculated (calc.) creatinine clearance > 50 mL/min
Patients must have adequate renal function as documented by a calculated creatinine clearance >= 60 mL/min, within 28 days prior to registration
Obtained within 28 days prior randomization: serum creatinine =< 1.5 x ULN for the lab or measured or calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 1.5 ULN OR measured or calculated creatinine clearance >= 30 mL/min
Or a calculated or measured creatinine clearance or radioisotope GFR >= 70ml/min/1.73m^2 obtained within 14 days prior to registration
Calculated creatinine clearance (Cr Cl) >= 50 ml/min; eligible for full dose methotrexate
Calculated creatinine clearance at least 30 mL/min.
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance > 60 ml/min.
Calculated creatinine clearance > 50 mL/min
PHASE II INCLUSION CRITERIA: Calculated creatinine clearance > 50 mL/min
Normal creatinine for age or a calculated creatinine clearance >= 60 mL/min/1.73 m^2
Estimated creatinine clearance >= 60 mL/min as calculated using the method standard for the institution
Calculated creatinine clearance >= 50 mL/min
Obtained =< 21 days prior to registration and confirmed prior to the first dose of study drug: Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >50 mL/min;
Calculated or measured creatinine clearance >= 30 ml/min, obtained =< 14 days prior to registration
Calculated creatinine clearance >= 60 ml/min.
Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min
Renal: Creatinine clearance of ? 40 mL/min, estimated or calculated.
Calculated creatinine clearance of >= 50 mL/min
Within 4 weeks before enrollment: Calculated creatinine clearance > 40 mL/min
Calculated creatinine clearance >= 10 mL/min
Creatinine =< 1.5 ULN or calculated creatinine clearance >= 50 ml/min
Obtained =< 28 days prior to registration: Creatinine =< 1.0 x ULN OR measured or calculated creatinine clearance (per institutional standard) must be >= 60 ml/min
Serum creatinine clearance of >= 50 ml/min (calculated or measured)
Creatinine > or = 2.0 x ULN or creatinine clearance < 50 mL/min (calculated).
Obtained within 14 days prior to enrollment: calculated creatinine clearance > 30 ml/min
Patients must have a calculated creatinine clearance of >= 35
Calculated or measured creatinine clearance >= 50 ml/min
Obtained =< 14 days prior to registration: Calculated or measured creatinine clearance >= 30 ml/min
Calculated creatinine clearance >= 30 mL/min/1.73 m^2
Creatinine clearance >= 40 mL/min (measured or calculated per local practice)
Calculated or measured creatinine clearance (method determined by the prescribing physicians) < 50 ml/min
Creatinine clearance >= 40 mL/min, estimated or calculated
Calculated creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 x the ULN and calculated creatinine clearance > 30 ml/min
Calculated creatinine clearance >= 45 mL/min
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >= 50 mL/min/1.73 m^2
Calculated creatinine clearance >= 30 mL/min
Either a serum creatinine ? ULN for age, or calculated or measured GFR ? 70 mL/min/1.73 m2
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance ? 30 mL/min
Calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 1.5 x ULN OR a measured creatinine clearance or calculated creatinine clearance >= 50 mL/min
Creatinine clearance > 50 ml/min (calculated creatinine clearance is permitted)
Calculated creatinine clearance > 30 ml/min
Calculated creatinine clearance >= 45 mL/min/1.73 m^2
Serum creatinine =< 1.5 x ULN or clearance >= 60 mL/min (measured or calculated)
Calculated creatinine clearance > 60 ml/min
Calculated creatinine clearance ?50 mL/min.
Calculated creatinine clearance of ? 50 ml/min.
Calculated Creatinine Clearance of 50 ml/min
Calculated creatinine clearance > 50 mL/min.
Calculated creatinine clearance >30ml/m
Calculated creatinine clearance of <60 mL/min in Stage 1 and <40 mL/min in Stage 2
Patients with moderate or severe renal impairment (calculated creatinine clearance of < 60 mL/min)
ORAL CAVITY SQUAMOUS CELL CARCINOMA COHORT: Calculated creatinine clearance > 50 mL/min
Creatinine clearance > 40 ml/min (calculated or measured)
Calculated creatinine clearance >= 30 mL/min
Estimated creatinine clearance >= 60 ml/min as calculated using the method standard for the institution
Calculated creatinine clearance of > 60 mL/min/m^2, within 28 days prior to registration.
Creatinine clearance (calculated or measured) > 30 mL/min
Calculated creatinine clearance >= 50 mL/min
Calculated (calc.) creatinine clearance > 45 mL/min
Serum creatinine =< ULN for the lab and measured or calculated creatinine clearance > 60 mL/min within 28 days before randomization
Calculated creatinine clearance > 70 mL/min/1.73 m^2
Calculated creatinine clearance >= 50 cc/min
Serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min
Patients must have a serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min
Measured or calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >= 30 mL/min within 14 days of enrollment
Within 6 weeks prior to randomization, the most recent serum creatinine must be =< ULN or measured or calculated creatinine clearance must be > 60 mL/min
Calculated or measured creatinine clearance >= 30 ml/min within 14 days prior to registration
Creatinine clearance (calculated or 24 hour) >= 30 ml/min
Calculated creatinine clearance >= 60 mL/min
Obtained within 28 days prior to registration: Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 60 mL/min
Calculated creatinine clearance ?60 mL/min/1.73m^2
Calculated creatinine clearance >= 30 mL/min within four weeks prior to randomization
Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min be obtained within 42 days prior to registration
CLINICAL/LABORATORY CRITERIA: Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 40 mL/min; this result must have been obtained within 28 days prior to registration
Calculated creatinine clearance ? 30 mL/min
Calculated Creatinine clearance>/= 45ml/min
Calculated creatinine clearance >= 45 ml/min
Measured or calculated creatinine clearance >= 40 ml/min
AMKL PATIENTS: Creatinine < 1.5 x ULN or calculated creatinine clearance > 30 ml/min
MF PATIENTS: Creatinine < 1.5 x ULN or calculated creatinine clearance > 30 ml/min
Calculated creatinine clearance > 60 mL/min
Calculated or measured creatinine clearance ? 40 mL/min
An average calculated creatinine clearance > 30 mL/min/1.73 m^2
Calculated creatinine clearance > 30 ml/min
Calculated creatinine clearance > 50 mL/min
Calculated creatinine clearance > 60 ml/min; the serum creatinine value used in the calculation must have been obtained within 14 days prior to Step 2 Randomization
Calculated creatinine clearance > 60 ml/min; the serum creatinine value used in the calculation must have been obtained within 14 days prior to Step 3 registration
Calculated creatinine clearance >= 30 mL/min
Creatinine clearance of >= 40 mL/min, estimated or calculated
Serum creatinine ? 1.5 × ULN or calculated or measured creatinine clearance ? 50 mL/min/1.73 m2
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 ml/min
Serum creatinine =< 1.5 x IULN or a calculated or measured creatinine clearance >= 50 mL/min; these tests (including creatinine [mg/dl] if using calculated creatinine clearance) must be obtained within 14 days prior to registration
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 1.5 x ULN, or calculated creatinine clearance >= 60 ml/min
Calculated creatinine clearance >= 60 mL/min
Calculated creatinine clearance >= 45 mL/min
Calculated creatinine clearance > 30 ml/min
Calculated creatinine clearance of ? 45 mL/min
Serum creatinine =< 1.5 x the ULN or calculated creatinine clearance >= 60 ml/min
Calculated creatinine clearance ? 60 mL/min.
Calculated creatinine clearance > 30 ml/min
Children (< 18 years old): calculated creatinine clearance must be > 60 mL/min
Calculated creatinine (calc. creat.) clearance >= 60 ml/min
Creatinine =< 1.5 x institutional ULN or creatinine clearance (calculated or measured) > 60 ml/min
Creatinine clearance (calculated creatinine clearance is permitted) should be > 40 ml/min
Creatinine clearance >= 50 ml/mm (can be calculated)
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min
Creatinine < 1.5 x ULN OR calculated creatinine clearance >= 50 mL/min
Creatinine =< 1.5 x ULN OR calculated creatinine clearance >= 60 ml/min
Calculated creatinine clearance > 30 mL/min/1.73 m^2
Calculated creatinine clearance >= 45 ml/min
Creatinine < ULN OR calculated creatinine clearance >= 50 mL/min\r\n* Creatinine clearance should be calculated by Cockcroft and Gault method
Subjects must have calculated creatinine clearance >= 30 ml/min
Creatinine of measured or calculated creatinine clearance of >= 50 cc/min
Calculated creatinine clearance >= 30 mL/min
Renal: Serum creatinine < 1.5 x ULN OR calculated creatinine clearance (CLcr) ? 60 ml/min
Renal: Serum creatinine < ULN OR calculated creatinine clearance (CLcr) of ? 60 ml/min
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance > 50 mL/min
Urothelial cancer patients should be ineligible for cisplatin based on one or more of the following:\r\n* Calculated creatinine clearance of < 60 mL/min (but >= 30 mL/min)\r\n* Solitary kidney\r\n* Karnofsky performance status < 80%
Calculated creatinine clearance of ? 60 ml/min.
Creatinine clearance equal or > 50 ml/min (calculated)
Creatinine clearance < 50 ml/min (calculated)
Calculated or measured creatinine clearance >= 45 mL/min
Creatinine >= 1.5 × ULN for the institution (or a calculated creatinine clearance < 60 mL/min/1.73 m2)
Serum creatinine =< 1.5 x ULN OR calculated creatinine clearance >= 50 mL/min
Serum creatinine > 1.5× ULN (or a calculated creatinine clearance < 60 mL/min/1.73 m2)
Calculated creatinine clearance >= 60 mL/min
Calculated creatinine clearance > 30 ml/min (unless demonstrated Hodgkin lymphoma involvement of the kidney)
Calculated creatinine clearance >= 30 mL/min
Calculated creatinine clearance > 50 mL/min.
Calculated creatinine clearance > 50 mL/min.
Calculated creatinine clearance > 20 mL/min per institutional standard
Calculated or measured creatinine clearance >= 60 mL/min
Calculated creatinine clearance >= 30 mL/min\r\n* For females, use 85% of calculated creatinine clearance (CrCl) value
Renal insufficiency (defined as calculated creatinine clearance < 30 mL/min)
Severe renal impairment (calculated creatinine clearance =< 29 cc/min)
Patients must have a calculated creatinine clearance > 30 mL/min; the serum creatinine value used in the calculation must have been obtained within 28 days prior to registration
Calculated or measured creatinine clearance >= 30 mL/min
Creatinine clearance (24 hour or calculated) > 50 ml/min
Renal disease, and we will use a calculated serum creatinine clearance over 30 ml/min at the screening appointment as an exclusion criteria
Creatinine clearance calculated >= 50 mL/min
Creatinine clearance < 50 ml/min (calculated or measured)
Creatinine clearance < 50 mL/min (calculated or measured)
Calculated creatinine clearance ? 50 mL/min
Calculated creatinine clearance >= 30 mL/min
Have a calculated creatinine clearance >= 50 mL/min
NORMAL VOLUNTEERS: Have a calculated creatinine clearance >= 50 ml/min
Calculated creatinine clearance >= 30 mL/min
calculated creatinine clearance > 100 mL/min/1.73 m2
Adequate renal function (calculated creatinine clearance ? 30 mL/min)
Calculated creatinine clearance >= 60 mL/min
Serum creatinine =< 1.2 x ULN or creatinine clearance >= 60 mL/min; obtained within 14 days prior to study entry
Creatinine clearance >= 45 ml/min documented within 28 days prior to step 1 registration
Calculated (calc.) creatinine clearance >= 50 mL/min\r\n* Estimated creatinine clearance for patients >= 18 years old will be estimated by the Jelliffe equation modified for body surface area (BSA); patients with creatinine clearance estimated > 70ml/min by this formula are eligible; if the creatinine clearance estimated by the Jelliffe method is >= 50 mL/min but =< 70 mL/min, then a second method to confirm a creatinine clearance of >= 50 mL/min is required; methods of estimating glomerular filtration rate (GFR) that can be used for this confirmation consist of a 12 or 24-hour urine creatinine clearance or a nuclear creatinine clearance test; if the confirmatory creatinine clearance is < 50 mL/min, then the patient is not eligible; if the confirmatory creatinine clearance is >= 50 mL/min, the patient is eligible; if the cause of the patient’s renal dysfunction is tumor obstructing the ureters, then eligibility can be determined by the study chair even if it does not meet these minimal requirements; for patients < 18 years old, it is strongly suggested that a radioisotope estimation of GFR be obtained; if a radioisotope test is not possible, an estimated creatinine clearance using either a 12 or 24 hour urine creatinine clearance or the Schwartz formula can be used; patients will be considered eligible if the creatinine clearance is > 70 mL/min; if the creatinine clearance estimated by the Schwartz formula or urine creatinine clearance is >= 50 mL/min but =< 70 mL/min, then a second method to confirm a creatinine clearance of >= 50 mL/min is required; methods of estimating GFR that can be used for this confirmation consist of a 12- or 24-hour urine creatinine clearance if the Schwartz formula or radioisotope method was used as the primary method or a radioisotope estimation of GFR if the Schwartz formula or urine creatinine clearance method was used as the primary method; if the confirmatory creatinine clearance is < 50 mL/min, then the patient is not eligible; if the confirmatory creatinine clearance is >= 50 mL/min, the patient is eligible
Serum creatinine clearance >= 30 ml/min
Creatinine clearance >= 30 mL/min
ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C): Creatinine clearance of at least 50 mL/min within 7 days prior to first dose of study agent
ELIGIBILITY CRITERIA - PHASE II (ARM D): Creatinine clearance of at least 50 mL/min within 7 days prior to first dose of study agent
Serum creatinine > 1.5 x ULN and/or creatinine clearance ? 50 mL/min
Creatinine clearance < 40 mL/min
Creatinine clearance > 50mL/min
Creatinine clearance =< 50 mL/min
Creatinine =< 1.5 x ULN or creatinine clearance > 60 ml/min
Creatinine clearance ? 40 mL/min (see Section 7.2.1 for instructions regarding calculation of creatinine clearance) performed within 28 days prior to randomization.
Obtained =< 2 weeks prior to registration: Creatinine clearance >= 50 mL/min
Creatinine clearance >= 60 mL/min/1.73 m^2
Within 28 days of study registration: Normal serum creatinine or creatinine clearance >= 60 ml/min/1.73 m^2
Creatinine clearance ? 50 mL/min
Serum creatinine ? 1.5 X ULN (OR creatinine clearance ? 60 mL/min/1.73 m2)
Serum creatinine =< 1.5 x institution’s ULN, or creatinine clearance >= 30 ml/min
Creatinine >1.5 times ULN concurrent with creatinine clearance <50 mL/min
Serum creatinine clearance >= 15 mL/min (performed within 14 days of treatment initiation)
Creatinine clearance >= 60 mL/min/1.73 m^2
Adequate organ function within 14 days of study registration including:\r\n* Normal serum creatinine or creatinine clearance >= 60 ml/min/1.73 m^2
Estimated creatinine clearance >= 45 ml/min
Creatinine within 2 times normal institutional limits OR creatinine clearance >= 30 mL/min/1.73 m^2; Note, dose adjustments are required for creatinine clearance (CrCl) >= 30 mL/min but =< 60 ml/min
Creatinine clearance ?60 mL/min
Serum creatinine >1.5 x ULN and/or measured creatinine clearance < 40 ml/min
Creatinine =< 1.5 or creatinine clearance >= 60 ml/ml
Creatinine clearance >= 40 mL/min
Estimated creatinine clearance must be > 40 mL/min
Creatinine clearance < 20 ml/min
Creatinine clearance > 30 mL/min
Creatinine clearance >= 30 mL/min
Creatinine clearance >= 15 ml/min
Creatinine less than 1. 5 X ULN and/or creatinine clearance >= 60 mL/min
Obtained within 21 days prior to cycle 1, day 1: serum creatinine clearance >= 50ml/min
Creatinine: Creatinine clearance > 25 ml/min
Serum Creatinine or Creatinine Clearance** ? 1.5 x ULN, > 50 mL/min
Creatinine clearance 30-75 mL/min
Creatinine clearance ? 50 mL/min
Creatinine clearance > 50 ml/min
Creatinine clearance >= 50 mL/min
Creatinine clearance ? 45ml/min
Creatinine clearance of >= 50 mL/min
Creatinine clearance >= 50 cc/min
Creatinine clearance < 30 ml/min
Creatinine clearance >= 30 ml/min
Within 3 days before the first dose of study drug: creatinine clearance > 50 mL/min
Creatinine clearance >= 50 mL/min.
Subjects with severe renal impairment (i.e., creatinine clearance =< 30 mL/min)
Creatinine clearance >= 40 mL/min/1.73 m^2
Creatinine clearance >= 60 mL/min/1.73 m^2
For Arm G, subjects must have an estimated creatinine clearance >= 50 ml/min.
Serum creatinine clearance >= 30 mL/min
Creatinine clearance >= 60 mL/min/1.73 m^2 unless reduced creatinine clearance felt by investigator to be acute and reversible
Creatinine clearance < 30 ml/min
Creatinine clearance >= 50 ml/min
Serum creatinine clearance >= 30 mL/min
Renal: Serum creatinine 1.5 x ULN or creatinine clearance 60 mL/min.
Creatinine clearance >= 60 mL/min/1.73 m^2 by Cockcoft-Gault
Creatinine clearance ? 50 ml/min
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2
Cabazitaxel: Creatinine clearance >= 30 mL/min/1.73 m^2
Creatinine clearance of >= 60 ml/min
Creatinine clearance >= 15 mL/min
Estimated creatinine clearance >=60mL/min/1.73 square meter (m^2)
Serum creatinine ? 2.0 x ULN or calculated creatinine clearance ? 45 mL/min based on the Cockroft-Gault GFR estimation. For newly diagnosed AML patients < 75 years of age, creatinine clearance ? 30 mL/min; for ? 75 years of age, creatinine clearance ? 45 mL/min.
Creatinine =< 2.0 mg/dL (adults) and creatinine clearance > 40 mL/min (pediatrics); adults with a creatinine > 1.2 or a history of renal dysfunction must have estimated creatinine clearance > 40 ml/min/1.73m^2
Estimated creatinine clearance > 45 ml/min
Estimated creatinine clearance > 40 mL/min (this must be checked twice before initiating therapy)
Creatinine clearance < 30 mL/min
Serum creatinine > 1.5 x ULN for age or creatinine clearance =< 60 mL/min/1.73 m^2
Creatinine clearance > 25 ml/min
Estimated or measured creatinine clearance > 50 mL/min
Creatinine clearance greater than 30 ml/min
Serum creatinine clearance >= 30 ml/min
Adequate kidney function with serum creatinine <2 x the ULN or creatinine clearance >30 mL/min
Serum creatinine ? 1.5 x ULN or estimated creatinine clearance ? 60 mL/min
Creatinine clearance >= to 50 ml/min
Serum creatinine =< 1.5 X ULN (OR creatinine clearance >= 60 mL/min/1.73 m^2)
Creatinine clearance < 30 ml/min which cannot be attributed to MCC metastasis
Creatinine clearance of >= 60 mL/min
Serum creatinine =< 2.5 or estimated creatinine clearance >= 30 ml/min and not dialysis-dependent
Creatinine (Cr) clearance >= 30 mL/min
Creatinine clearance >= 45 mL/min
Estimated creatinine clearance must be > 40 mL/min
Creatinine clearance of < 50 ml/min
Estimated creatinine clearance < 15 mL/min
Creatinine clearance >= 30 mL/minutes
Creatinine clearance (Clcr) > 25 mL/min
Creatinine clearance < 30 ml/min
Estimated creatinine clearance >= 50 mL/min
Creatinine clearance >= 30 mL/min/1.73 m^2
Creatinine clearance < 50 mL/min/1.73m^2
Estimated creatinine clearance at least 50 ml/min
Creatinine clearance > 50 ml/min/1.73 m^2 (Schwartz formula)
Relapsed/refractory MCL: Creatinine (Cr) clearance >= 30 mL/min
Newly diagnosed MCL: Creatinine (Cr) Clearance >= 30 mL/min
Creatinine clearance >= 50 ml/min/1.73m^2
Creatinine clearance of >= 60 mL/min
Creatinine clearance equal to or more than 50 mL/min
Creatinine clearance of >= 60 mL/min
Creatinine clearance of >= 60 ml/min
Creatinine clearance > 60 ml/min
Patients with renal insufficiency or creatinine (cr) clearance < 60 ml/min
Creatinine =< 1.5 or creatinine clearance >= 60 ml/min
Estimated creatinine clearance >= 50 ml/min
Adequate renal function defined as creatinine =< 2.0 mg/dl (adults) or estimated creatinine clearance > 40 ml/min (pediatrics); all adults with a creatinine > 1.2 or a history of renal dysfunction must have estimated creatinine clearance > 40 ml/min
All adults with a creatinine > 1.2 or a history of renal dysfunction must have estimated creatinine clearance > 40 ml/min
Creatine clearance >= 40 ml/min
Creatinine < 2.0 (adults) or creatinine clearance > 40 ml/min (pediatrics)
Renal: creatinine =< 2.0 mg/dl (adults) and creatinine clearance > 40 ml/min (pediatrics); adults with a creatinine > 1.2 or a history of renal dysfunction must have estimated creatinine clearance > 40 ml/min
Creatinine clearance >= 50 mL/min (repeat if more than 3 days before the first dose)
Creatinine >1.5 x ULN, or measured creatinine clearance <60 mL/min, OR 24-hour measured urine creatinine clearance <60 mL/min OR calculated creatinine clearance <60mL/min estimated using the Cockcroft-Gault equation:
Creatinine clearance ? 45 cc/min
Creatinine clearance ? 30 mL/min
Within 14 days prior to first dose of study drug treatment: Creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 × ULN or creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine clearance >= 60 mL/min/1.73 m^2
Creatinine clearance >= 50 mL/min
Within 28 days prior to administration of therapy: Creatinine clearance >= 50 mL/min
Creatinine clearance < 50 ml/min
Serum creatinine =< 1.5 × ULN or creatinine clearance >= 50 mL/min
Creatinine clearance >= 40 mL/min/1.73 m^2
Patient with severe renal disease (i.e. creatinine greater than 3 times normal for age; creatinine clearance less than 50 ml/min/1.73m^2)
Creatinine clearance > 30 cc/min
Creatinine =< 1.5 times ULN OR measured creatinine clearance of >= 60 mL/min 1.73 m^2
Creatinine clearance >= 60 mL/min, unless secondary to renal involvement by lymphoma; for creatinine clearance < 50 mL/min due to kidney involvement by tumor
Creatinine clearance within 2 weeks of registration must be at least 60 ml/min
Serum creatinine ? 1.5 x ULN; or a creatinine clearance ?40 mL/min;
Serum creatinine ? 2 x ULN or estimated creatinine clearance ? 50 ml/min.
Estimated creatinine clearance ? 30 mL/min.
Creatinine clearance 30 to 69 mL/min.
Estimated creatinine clearance ? 30 mL/min.
Estimated Creatinine Clearance ?30 mL/min
Creatinine clearance >= 50 mL/min
Creatinine clearance or estimated GFR . 60 mL/min/1.73m2
Renal: Creatinine clearance ?50mL/min;
Creatinine clearance inferior to 30 mL per min (MDRD Formula).
Creatinine clearance >=50 milliliter per minutes (mL/min).
Estimated Creatinine Clearance ?30 mL/min
For patients who have creatinine clearance that meets > 50 ml/min they must not have received prior systemic doxorubicin
Creatinine clearance > 50 ml/min
Creatinine clearance >= 30 mL/min
Measured creatinine clearance > 50 ml/min or estimated creatinine clearance > 50 ml/min
Creatinine clearance >= 30 mL/min
Serum Creatinine or Creatinine Clearance** ? 1.5 x ULN, > 50 mL/min
Creatinine clearance ? 60 cc/min
Creatinine =< 1.5 x ULN or creatinine clearance >= 60 mL/min/1.73 m^2
Estimated creatinine clearance >= 30ml/min
Creatinine clearance >= 40 mL/min
Renal: Estimated or measured creatinine clearance >= 60 mL/min.
Subject has severe renal impairment (creatinine clearance < 30 ml/min).
Creatinine clearance >= 45 mL/min
Pediatric patients must have creatinine clearance >= 60 mL/min/1.73 m^2 regardless of serum creatinine level
Creatinine (Cr) clearance >= 30 mL/min
Creatinine clearance > 30 ml/min
Creatinine =< 1.5 times ULN OR measured creatinine clearance > 60 mL/min
Creatinine clearance < 50 mL/min
Creatinine clearance of >= 60 ml/min
Creatinine clearance >= 50 mL/min
Creatinine clearance ? 60mL/min
Creatinine (Cr) clearance >= 60 mL/min
Normal serum creatinine or creatinine clearance >= 60 ml/min/1.73 m^2
Estimated creatinine clearance of >= 40 ml/min
Creatinine Clearance of ? 50 mL/min
Creatinine clearance: the standard Cockcroft and Gault formula must be used to calculate creatinine clearance (CrCl) for enrollment or dosing; also include in the pre-treatment or baseline text portion of the protocol, the 'On Study Evaluations or During Treatment' for every pemetrexed treatment day, and also capture in the study Schedule of Events; no dosage adjustment is needed in patients with creatinine clearance > 45 mL/min; insufficient numbers of patients have been studied with creatinine clearance < 45 mL/min to give a dose recommendation; therefore, pemetrexed should not be administered to patients whose creatinine clearance is < 45 mL/min
Creatinine clearance >= 50 mL/min
creatinine clearance of < 30 mL/min
Creatinine clearance of > 60 ml/min
Estimated creatinine clearance < 50 ml/min
Renal insufficiency of creatinine clearance <40mL/min
Creatinine clearance estimated to be >= 30 ml/min
Creatinine clearance < 40 ml/min
Patients must have either (a) normal kidney function (i.e. creatinine =< 1.5 X upper limit of normal [ULN] OR calculated creatinine clearance >= 60 mL/min by the modified Cockcroft and Gault Formula OR a creatinine clearance >= 60 mL/min obtained from a 24-hour urine collection) or (b) moderate or severe renal dysfunction (i.e. creatinine clearance < 60 mL/min and >= 20 mL/min)
Creatinine clearance (Clcr) > 25 mL/min
Creatinine clearance >= 40 ml/min
creatinine clearance < 70 mL/min, or
Estimated creatinine clearance (CLcr) > 25 ml/min
Creatinine clearance of >= 60 ml/min
Creatinine =< 2.0 X ULN OR creatinine clearance >= 30 mL/min/1.73 m^2
Creatinine clearance >= 60 ml/mm
Creatinine clearance >= 30 ml/min
Creatinine clearance > 30 mL/min
Serum creatinine < 2 x ULN or creatinine clearance > 60 mL/min
Serum creatinine =< 1.5 X ULN and stable X 1 month OR creatinine clearance >= 60 Ml/min/1.73 m^2
Creatinine clearance >= 30 mL/min
Serum creatinine >1.5 x ULN or creatinine clearance ? 45 mL/min
Serum creatinine =< 1.5 x ULN or creatinine clearance >= 50 mL/min
Creatinine Clearance ? 50 ml/min
Creatinine clearance < 30 ml/min which cannot be attributed to MCC metastasis
Patients with creatinine clearance: < 50 mL/min are excluded from this protocol; capecitabine is contraindicated in severe renal impairment (clearance < 40 mL/min)
Creatinine clearance ? 30 mL/min
Creatinine clearance > 50 ml/min
Creatinine clearance must be > 60ml/min
Creatinine clearance >= 40mL/min
Creatinine clearance >= 50 ml/min
Severe renal impairment (creatinine clearance =< 30 ml/min)
Serum creatinine =< 1.5 x ULN or creatinine clearance >= 50 mL/min
Creatinine ?2.0 x ULN or Creatinine Clearance ?40 mL/min
Creatinine clearance ? 50 mL/min
Serum creatinine =< 1.5 x ULN and creatinine clearance > 30 ml/min
Creatinine clearance > 40 ml/min
Serum Creatinine ? 1.5 x ULN, or Creatinine Clearance > 45mL/min
Creatinine clearance >= 50 cc/min
Estimated creatinine clearance of ?40 mL/min
Creatinine clearance >= 50 mL/min
Measured creatinine clearance >= 60 mL/min
Creatinine clearance >= 40 mL/min
Creatinine Clearance < 45 mL/min
Subjects with creatinine clearance ?10 mL/min who are not being treated with continuous renal replacement therapy (CRRT).
Patients must have a serum creatinine within normal limits, or an estimated or measured creatinine clearance >= 65 ml/min
Total Cumulative Illness Rating Scale (CIRS) > 6 and/or creatinine clearance < 70 ml/min
Estimated serum creatinine clearance > 60 ml/min
Creatinine clearance of > 40 ml/min/1.73m^2
Creatinine clearance >= 25 mL/min
Creatinine clearance >= 30 mL/min
Must have a serum creatinine < 2.0 and creatinine clearance > 30 ml/min/m^2; other organ dysfunction is eligible at the discretion of the Principal Investigator (PI)
Patients with a creatinine clearance of < 60 ml/min
Patients with severe renal insufficiency, defined and confirmed by an estimated creatinine clearance equal or lower than 30 mL/min, per institutional laboratory.
Patients with severe renal impairment defined as creatinine clearance of 15-29 mL/min and/or diagnosed with stage 4 chronic kidney disease
Moderate to severe renal failure (creatinine clearance [Clcr] < 30 mL/min)
Patients with a creatinine clearance < 30 mL/min
Acute or chronic renal insufficiency with creatinine clearance < 30 mL/min, drawn within 28 days of consent
Creatinine clearance >= 50 ml/min
Estimated creatinine clearance ? 50ml/min
Creatinine clearance >= 30 mL/min
Estimated creatinine clearance >= 30 ml/min
Patients with creatinine clearance of less than or equal to 50 ml/min
Creatinine clearance ? 30 mL/min
Creatinine =< 1.5, or creatinine clearance >= 45 mL/min
known renal insufficiency with estimated creatinine clearance (eGRF) of less than 54 mL/min;
Creatinine clearance >= 50 cc/min
Estimated creatinine clearance >= 60 ml/min
Significant renal disease as defined by creatinine clearance less than 30 mL/min
Creatinine clearance >= 50 cc/min
Creatinine clearance >= 30 mL/min
Estimated serum creatinine clearance of ? 50 mL/min
Age-adjusted normal serum creatinine or a creatinine clearance ? 40 ml/min
Creatinine > 1.5 x ULN or creatinine clearance < 60 mL/min from assays obtained < 2 weeks prior to study enrollment
Creatinine > 1.5 x ULN or creatinine clearance < 60 mL/min, from assays obtained < 2 weeks prior to study enrollment
Creatinine >1.5 x ULN or creatinine clearance < 60 mL/min
Creatinine > 1.5 x ULN or creatinine clearance < 60 mL/min
Creatinine > 1.5 x ULN or creatinine clearance < 60 mL/min, from assays obtained < 2 weeks prior to study enrollment
Severe renal impairment (i.e. creatinine clearance < 40 mL/min)
Estimated creatinine clearance < 50 mL/min
Serum creatinine >2.0 x ULN, or estimated creatinine clearance <40mL/min
Renal: serum creatinine within normal limits (WNL), defined as within 25% of the institution's stated reference range, or a calculated creatinine clearance >45 mL/min/1.73 m. sq. for patients with abnormal, increased, creatinine levels.
Serum creatinine within normal range, or if serum creatinine outside normal range, then glomerular filtration rate (GFR) > 40 mL/min/1.73m2 as calculated with the Cockcroft-Gault equation with adjustment if total body weight is ? 125% of ideal body weight.
Serum creatinine within normal range, or if serum creatinine outside normal range, then GFR > 40 mL/min/1.73m2 as calculated with the Cockcroft-Gault equation with adjustment if total body weight is ? 125% of ideal body weight.
Serum creatinine =< 2 x upper limit of reference range or creatinine clearance >= 30 ml/min
Adequate renal function, as defined by estimated serum creatinine clearance >= 60 ml/min and a normal serum creatinine for age
Serum creatinine within normal range
Creatinine =< 1.2 x normal range prior to biopsy
Serum creatinine within normal range, or if serum creatinine outside normal range, then renal function (measured or estimated creatinine clearance or glomerular filtration rate [GFR]) > 40mL/min/1.73 m^2
Serum creatinine within normal range with a creatinine clearance >= 30 ml/min
Serum creatinine within normal range for age, or if serum creatinine outside normal range for age, then renal function (creatinine clearance or glomerular filtration rate [GFR]) > 40 mL/min/1.73m^2
Serum creatinine =< 1.2 mg/dl or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 40 ml/min (measured or calculated/estimated)
Serum creatinine =< 1.2 mg/dL or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 40 ml/min (measured or calculated/estimated)
Serum creatinine within normal range for age, or if serum creatinine outside normal range for age, then renal function (creatinine clearance or glomerular filtration rate [GFR]) > 40 mL/min/1.73m^2
Renal: serum creatinine within normal limits (WNL), defined as within 10% of the institution's stated reference range, or a calculated creatinine clearance >60 mL/min/1.73 m2 for patients with abnormal, increased, creatinine levels. Patients with Multiple Myeloma (only): serum creatinine ? 2.5 the institutional upper limit of the normal range and a calculated creatinine clearance > 40 mL/min/1.73 m2.
Renal insufficiency (creatinine clearance < 40 ml/min) or liver insufficiency (serum bilirubin > 2 times the upper normal range and/or serum transaminases (AST/SGOT, ALT/SGPT, but not gamma Glutamyl Transpeptidase) >3 times the upper normal range). Creatinine clearance may be calculated according to validated formulas (Crockoft's or MDRD)
Serum creatinine within 1.5 x normal range for age OR creatinine clearance with a recommended eGFR ? 50 mL/min/1.73m^2
Serum creatinine within 1.5 x normal range for age OR creatinine clearance with a recommended eGFR ? 50 mL/min/1.73m^2
Renal: serum creatinine (SCr) within normal range for age (see table 2.3). If SCr is outside normal range for age, creatinine clearance (CrCl) > 40 mL/min/1.73m2 must be obtained (measured by 24-hour (hr) urine specimen or nuclear glomerular filtration rate (GFR), or calculated GFR (by Cockcroft-Gault formula for those aged ? 18 years; by Original Schwartz estimate for those < 18 years))
Serum creatinine =< 1.5 x the upper limit of normal range, or, if serum creatinine > 1.5 x the upper limit or normal range, then the creatinine clearance must be >= 60 mL/min
Serum creatinine =< 1.2 mg/dl or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 40 ml/min (measured or calculated/estimated) with dose adjustment for fludarabine for < 70 ml/min
Subjects with a determination of renal function based on: serum creatinine =< 1.5 mg/dL or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 60-ml/min/1.73 m^2
Renal: serum creatinine < 1.5 mg/dl or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 40 ml/min (measured or calculated/estimated)
Renal: serum creatinine =< 1.2 mg/dl or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 40 ml/min (measured or calculated/estimated) with dose adjustment of fludarabine for < 70 ml/min
Serum creatinine =< 1.5 x normal
Renal: Serum creatinine within normal range for age, or if serum creatinine outside normal range for age, then renal function (creatinine clearance or GFR) > 70mL/min/1.73m2.
Renal function: Age-adjusted normal serum creatinine is required. A 24-hour creatinine clearance value > 60 mL/min/1.73 m2 (updated Schwartz formula or nuclear GFR) must be obtained if serum creatinine is elevated.
Renal insufficiency or serum creatinine above the normal reference range
Renal: serum creatinine < 1.2 mg/dl or if serum creatinine is outside the normal range, then creatinine clearance (CrCl) > 50 ml/min (measured or calculated/estimated)
Serum creatinine within normal range, or if serum creatinine is outside normal range, then renal function (measured or estimated creatinine clearance or glomerular filtration rate [GFR]) >= 40 mL/min/1.73 m^2
Serum creatinine > 1.5 times upper reference range
Serum creatinine =< 1.5 times upper reference range
Serum creatinine of =< 1.5 mg/dL; if creatinine > 1.5 mg/dL, creatinine clearance must be >= 60 mL/minute
Serum creatinine =< 1.5 x mg/dL OR measured or calculated creatinine clearance >= 50 mL/min; creatinine measurements must be obtained within 28 days prior to registration
Creatinine =< 1.5 mg/dL OR creatinine clearance >= 45mL/min
Obtained within 14 days prior to treatment start: Serum creatinine (CREAT) =< 1.5 mg/dL or creatinine clearance >= 50 mL/min
Creatinine < 1.4 mg/dl and/or a measured creatinine clearance > 60 cc/min
Serum creatinine =< 1.5 times ULN OR if serum creatinine >= 1.5 mg/dL, calculated creatinine clearance >= 30 mL/min
Or, if serum creatinine > 1.5 mg/dL: calculated creatinine clearance (ClCR) > 50 mL/min
Creatinine < 1.5 mg/dL and calculated creatinine clearance >= 60 cc/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL or estimated creatinine clearance >= 50 ml/min
Serum creatinine < 140 ?mol/L (< 1.6 mg/dL) or creatinine clearance > 60 mL/min.
Chemistry Total bilirubin ? 2 mg/dL AST and/or ALT > 3 x ULN Serum creatinine > 1.5 x ULN and/or creatinine clearance ? 45 mL/min
Creatinine at or below IULN (males 0.7-1.30 mg/dl; females 0.6-1.10 mg/dl) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2
Serum creatinine =< 2.0 mg/dl or a calculated creatinine clearance of > 60 ml/min
Obtained =< 21 days prior to registration: creatinine =< 2 mg/dL or creatinine clearance >= 40 mL/min
Serum creatinine < 1.5 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine > 1.5 mg/dL. If serum creatinine > 1.5 mg/dL, the measured creatinine clearance must be measured and patient is eligible if creatinine clearance > 45 mL/min.
Serum creatinine < 1.5 mg/dL or creatinine clearance >= 50 mL/min
Creatinine =< 1.5 mg/dL OR calculated (calc.) creatinine clearance >= 30 mL/min
Obtained =< 35 days prior to registration: creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min
Have acceptable renal function defined as: Serum creatinine ? 1.5 × ULN, OR calculated creatinine clearance ? 45 mL/min for patients with creatinine levels above 1.5 mg/dL
Serum creatinine =< 2.5 mg/dL or a calculated creatinine clearance >= 50 mL/min
Serum creatinine < 2 mg/dL OR calculated creatinine clearance (CrCl) > 30 ml/min
Creatinine > 1.5 mg/dl at the present time; patients with a known history of creatinine > 1.5 mg/dl must have a current estimated creatinine clearance of > 40 ml/min
Creatinine > 2.0 mg/dl at the present time; patients with a known history of creatinine > 1.5 mg/dl must have a current estimated creatinine clearance > 40 ml/min
creatinine ? 2.0 mg/dL, or calculated creatinine clearance ? 45 mL/min
Serum creatinine < 1.5 mg/dL OR if serum creatinine > 1.5 mg/dL then calculate creatinine clearance (CrCL) > 30 mL/min
Serum creatinine <= 1.5 mg/dL. (or estimated creatinine clearance >= 50 ml/min/1.73 m2)
Serum creatinine =< 1.5 mg/dL or estimated creatinine clearance >= 60 ml/min using Crockcroft-Gault estimation
Serum creatinine < 1.4 mg/dL or calculated creatinine clearance (CrCl) >= 30 mL/min
Creatinine < 2.0 mg/dL (for adults) or creatinine clearance > 60 ml/min (for children)
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine < 2.0 mg/dL OR creatinine clearance (Cockcroft) >= 40 mL/min/1.73 m^2
Creatinine =< 1.5 mg/dL OR creatinine clearance >= 45 mL/min
Serum creatinine ? 1.5 mg/dl OR calculated creatinine clearance ? 50 for those patients with creatinine greater than 1.5 obtained ? 14 days prior to randomization
Either creatinine > 2.0 mg/dL or creatinine clearance < 30 mL/min
Serum creatinine =< 2.0 mg/dl and/or creatinine clearance of > 40 ml/min (excludes multiple myeloma patients receiving high dose melphalan conditioning)
Serum creatinine =< 2 mg/dL OR creatinine clearance > 50 mL/min.
Serum creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2.
Serum creatinine < 2.5 mg/dL or creatinine clearance > 30 cc/min
Serum creatinine ? 1.5 mg/dL OR creatinine clearance ? 50 mL/min/1.73 m2 for subjects with creatinine >1.5 mg/dL
Creatinine =< 2.0 mg/dL or calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 2.0 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2, at the time of enrollment
Creatinine clearance >= 50 mg/dL within 30 days of registration
Creatinine levels < 2 mg/dL; or creatinine clearance > 40 mL/min
Serum creatinine less than or equal to 1.5 mg/dl unless the measured creatinine clearance is greater than 60 mL/min/1.73 m^2
Creatinine =< 2.0 mg/100 ml
Serum creatinine =< 2.0 mg/dl or creatinine clearance > 60 ml/min within 30 days of enrollment to study
Serum creatinine =< 1.8 mg/dL or creatinine clearance > 50 mL/min
Serum creatinine =< 1.5 mg/dL, or if creatinine > 1.5 mg/dL, calculated creatinine clearance of >= 50 mL/min by 24 hour creatinine clearance or Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)
Serum creatinine <1.5 mg/dl or creatinine clearance?50 mL/min
Patients must have creatinine of less than or equal to 1.5 mg/dL or creatinine clearance > 60 ml/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 60 mL/min
Creatinine =< 2.0 mg/dl (adults) and creatinine clearance >= 40 mL/min (pediatrics); adults with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have estimated creatinine clearance >= 40 ml/min/1.73m^2
Adequate renal function as demonstrated by a serum creatinine ?1.5 mg/dL or a creatinine clearance >60 mL/min;
Serum creatinine less than or equal to 1.3 mg/dL and/or creatinine clearance > 40 mL/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine =< 1.8 mg/dL and/or estimated serum creatinine clearance >= 50 ml/min
Creatinine =< 1.5 mg/dL or creatinine clearance >= 60 ml/min
Serum creatinine > 2.2 mg/dl or blood urea nitrogen (BUN) > 40 mg/dl; note: if creatinine is greater than 1.5 x upper limit of normal (ULN), creatinine clearance must be greater than 60ml/min
Creatinine > 2 mg/dL and an estimated creatinine clearance =< 40 mL/min
Calculated creatinine clearance >= 30 mL/min or serum creatinine =< 1.5 mg/dl
Creatinine below ULN (males 0.7-1.30 mg/dl; females 0.6-1.10 mg/dl) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
Serum creatinine of < 1.5 mg/dL, and a measured creatinine clearance of > 60 mL/min
Serum creatinine =<1.5 mg/dL or creatinine clearance > 50 ml/min; some patients with minor deviations may be accepted on protocol after discussion with the PI
Serum creatinine < 1.5 mg/dl or creatinine clearance (CrCl) > 60 mL/min, performed within 28 days prior to registration
Creatinine =< 1.5 mg/dL OR creatinine clearance >= 30 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 mg/dL
Within 30 days of first vaccination: Serum creatinine =< 1.2 mg/dl or creatinine clearance > 60 ml/min
Serum creatinine ? 2.5 mg/dL or calculated creatinine clearance (CrCl) ?25.0 mL/min.
Serum creatinine =< 1.5 mg/dL or a measured creatinine clearance >= 50 mL/min (to be performed within 7 days prior to start of study treatment)
Serum creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2
Serum creatinine =< 1.5mg/dl OR calculated creatinine clearance >= 50 for those patients with creatinine greater than 1.5
RECIPIENT: Creatinine: adult patients: =< 2.0 mg/dl and creatinine clearance >= 30 ml/min; pediatric patients (< 18 years old) creatinine < 1.5 mg/dL and a creatinine clearance > 30 mL/min/1.73 m^2
Serum creatinine =< 2 mg/dl or creatinine clearance greater or equal than 40 cc/min; creatinine for pediatric patients =< 2 mg/dl or =< 2 times upper limit of normal for age (whichever is less)
Serum creatinine < 1.5 mg/dL or creatinine clearance greater or equal than 60 cc/min as defined by the Cockcroft-Gault Equation: Males(mL/min):(140-age)*IBW(kg) / 72*(serum creatinine (mg/dl)); Females (mL/min):0.85*(140-age)*IBW(kg) / 72*(serum creatinine (mg/dl)).
Serum creatinine =< 1.5 mg/dL (if > 1.5 mg/dL, then creatinine clearance should be > 60 mL/min)
Serum creatinine < 1.5 mg/dL OR creatinine clearance > 60 mL/min
Or, if > 1.5 mg/dL: calculated creatinine clearance (ClCR) >= 30 mL/min
Serum creatinine =< 2.0 mg/dl or creatinine clearance >= 60 mL/min
Serum creatinine of =< 1.5 mg/dL, and a measured creatinine clearance of >= 60 mL/min
Creatinine < 1.7mg/dL or creatinine clearance >= 60 cc/min (performed within 14 days prior to registration)
Creatinine < 1.5 mg/dL or calculated creatinine clearance > 60 mL/min
Creatinine must also be < 1.8 mg/dl or a creatinine clearance > 50 ml/min
Creatinine: \r\n* Patients: =< 2.0 mg/dl or creatinine clearance >= 30 ml/min/1.73 m^2\r\n* Pediatric patients (< 18 years old): creatinine =< 1.5 mg/dl or a creatinine clearance of >= 30 mL/min/1.73 m^2
Serum creatinine =< 2.0 mg/dl or creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above 2.0 mg/dl
Estimated serum creatinine clearance >= 50 ml/min and/or serum creatinine =< 1.8 mg/dL
Adequate renal function defined as creatinine =< 2.0 mg/dl (adults) or creatinine clearance > 40 ml/min (pediatrics)
Creatinine =< 2.0 mg/100 ml
Creatinine =< 2.0 mg/dl or creatinine clearance > 50 ml/min
Creatinine =< 2.0 mg/dl or creatinine clearance > 50 ml/min
Creatinine =< 1.5 mg/dl or creatinine clearance >= 50 ml/min
Creatinine =< 2.0 mg/dl (adults) and creatinine clearance >= 40 mL/min (pediatrics); adults with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have estimated creatinine clearance >= 40 ml/min/1.73 m^2
Creatinine < (1.5 mg/dL) during screening evaluation (> 1.5 is allowed if EGFR > 45 mL/min/1.73 m^2)
Serum creatinine ? 2 mg/dL and creatinine clearance ? 60 ml/hr
Serum creatinine ? 2 mg/dL and creatinine clearance ? 40 ml/hr
Serum creatinine ? 1.5 x Upper Limit of Normal or creatinine clearance ? 40 mL/min (if using the Cockcroft-Gault formula below): Female Creatinine Clearance = [(140 - age in years) x weight in kg x 0.85] / [72 x serum creatinine in mg/dL] Male Creatinine Clearance = [(140 - age in years) x weight in kg x 1.00] / [72 x serum creatinine in mg/dL]
Serum creatinine > 2.0 mg/dL or creatinine clearance of < 30 mL/min
Adequate renal function documented by serum creatinine of 1.5 mg/dl or less, or calculated creatinine clearance > 50 ml/min.
Serum creatinine must be less than 2.0 mg/dl obtained within 2 weeks prior to study enrollment; if serum creatinine is greater than 1.5 mg/dl, the creatinine clearance calculated from a 24 hour urine collection must be greater than 40 ml/min
Stable creatinine =< 2.0 mg/dL or creatinine clearance >= 60 ml/min performed within 60 days of enrollment
Creatinine <2.0 mg/dL or creatinine clearance ?50 mL/min
Calculated creatinine clearance must be > 60 mL and serum creatinine =< 2 mg/dL
Obtained within 28 days prior to registration: Creatinine =< 1.5 mg/dL or creatinine clearance >= 60 mL/min is recommended; however, institutional norms are acceptable
Obtained =< 7 days prior to registration: Creatinine =< 2.0 mg/dL or creatinine clearance > 50 mL/min
Serum creatinine <2 mg/dL, or creatinine clearance ?1.5 × ULN.
Serum creatinine =< 2.0 mg/dL or calculated creatinine clearance >= 60 mL/min
Serum creatinine < 2.0 mg/dl, creatinine clearance >= 50 ml/mm (can be calculated or measured)
Patients must have serum creatinine =< 2 mg/dl with creatinine clearance >= 60 ml/min (either calculated or measured)
Creatinine < 1.5 mg/dl or creatinine clearance > 60 cc/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 40 ml/min/1.73 m^2 unless lymphoma related
Serum creatinine less than or equal to 1.6 mg/ml or the creatinine clearance must be greater than 70 ml/min/1.73 m^2
Creatinine =< 2.0 mg/dl (adults) or creatinine clearance > 40 ml/min. ); all adults with a creatinine > 1.2 or a history of renal dysfunction must have creatinine clearance (must be > 40 ml/min)
Renal function: calculated or measured creatinine clearance >= 50 ml/min and/or serum creatinine =< 1.6 mg/dl
Creatinine < 2.0 mg/dL or creatinine clearance (CrCl) >= 60 mL/min
Serum creatinine less than or equal to 1.5 mg/dl unless the measured creatinine clearance is greater than 60 mL/min/1.73 m^2
Serum creatinine\r\n* Male: =< 1.7 mg/dl\r\n* Female: =< 1.5 mg/dl\r\n* Or estimated creatinine clearance of >= 60 ml/min
Creatinine ? 2 mg/dL OR creatinine clearance ? 50 mL/min
Creatinine < 2.0 mg/dL OR creatinine clearance > 60 mL/min/1.73 m^2
Creatinine of less than 2.0 mg/dL, or if the patient has a serum creatinine >= 2.0, a measured creatinine clearance (Ccr) must be > 60 mL/min/1.73m^2
Creatinine < 2.0 mg/dL, or creatinine clearance > 60 mL/min
Serum creatinine of < 1.5 mg/dl and/or creatinine clearance of > 60 mL/min
Creatinine =< 2.0 mg/dl or creatinine clearance > 50 ml/min
Creatinine =< 1.4 mg/dL or creatinine clearance >= 50 mL/min
Creatinine =< 1.5 mg/dl or creatinine clearance >= 50 ml/min
Creatinine less than or equal to 1.5 mg/dL, or if > 1.5 mg/dL, creatinine clearance must be at least 50 ml/min
Creatinine =< 1.5 mg/dL OR creatinine clearance >= 30 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 mg/dL
Serum creatinine =< 1.3 mg/dL if male or =< 1.1 mg/dL if female or and calculated creatinine clearance >= 55 ml/min/1.73 m^2
(R) Renal insufficiency (serum creatinine >2 mg/dl)(177 µmol/L or more) or creatinine clearance < 40 ml/min
Serum creatinine (Cr) > 1.5 mg/dL or creatinine clearance < 50 ml/min/1.73 m^2 unless lymphoma related
Serum creatinine < 2 mg/dL or creatinine clearance (CrCl) > 30 mL/min
Renal function: Estimated creatinine clearance ? 45 ml/min or serum creatinine ? 2.5 mg/dL
Serum creatinine < 1.5 mg/dl or creatinine clearance (CC) ? 50 ml/min
Serum creatinine =< 1.6 mg/dl or a calculated creatinine clearance >= 60 cc/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50mL/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance >=50 mL/min.
Obtained within 14 weeks prior to registration on study: serum creatinine < 2.0 mg/dl and creatinine clearance > 40 mL/min
Serum creatinine > 2 mg/dL OR creatinine clearance level (CrCL) < 30ml/min
Obtained =< 21 days prior to registration: Estimated creatinine clearance >= 60 mL/min or a creatinine =< 2.2 mg/dL
Creatinine clearance > 45 mL/min (or serum creatinine [SCr] =< 1.5 mg/dL), normal within 2 weeks prior to start of treatment
Creatinine =< 1.5 mg/dL OR creatinine clearance (measured) >= 50 mL/min
Creatinine < 1.5 mg/dl or creatinine clearance > 40 ml/min
Serum creatinine =< 1.5 mg/dl; creatinine (Cr) clearance should be > 50 mL/min
Serum creatinine =< 1.5 mg/dL (133 umol/L) or, if > 1.5 mg/dL: calculated creatinine clearance (ClCR) >= 50 mL/min (tested within 14 days prior to registration)
Creatinine =< 1.8 mg/dL OR a calculated creatinine clearance >= 60 mL/hr within 4 weeks of enrollment
Creatinine =< 1.5 mg/dL (133 umol/L), or if > 1.5 mg/dL, calculated creatinine clearance >= 50 cc/min)
Serum creatinine =< 2.0 mg/dl or creatinine clearance > 60 ml/min
Creatinine < 2.0 mg/dL or creatinine clearance >= 50 mL/min
Creatinine =< 2.0 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL OR measured or calculated creatinine clearance >= 50 mL/min
Participants must not have a creatinine > 3 mg/dl or a GFR < 30 mL/min/1.73m^2
Renal function creatinine =< 2.0 mg/dL and/or creatinine clearance >= 50 ml/min
Serum creatinine < 1.4 mg/dl in females and < 1.5 mg/dl in males, and creatinine clearance > 60 mL/min
Serum creatinine =< 1.5 mg/dL and/or creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL (133 umol/L)\r\n* Or, if > 1.5 mg/dL: calculated creatinine clearance (ClCR) >= 30 mL/min to >= 50 mL/min
Creatinine clearance >= 45 mL/min; (creatinine < 2 mg/dL to receive cisplatin)
Creatinine < 1.8mg/mL
Serum creatinine of =< 1.5 mg/dl or calculated creatinine clearance of >= 60 mL/min
Creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
Adults: calculated creatinine clearance must be > 60 mL and serum creatinine =< 2 mg/dL
Serum creatinine =< 1.5 mg/dL (133 umol/L); or, if serum creatinine > 1.5 mg/dL: calculated creatinine clearance (ClCR) >= 50 mL/min
Serum creatinine =< 1.5 mg/dL or calculated creatinine clearance >= 60 mL/min
Serum creatinine < 1.4 mg/dl or creatinine clearance >= 60 ml/min (prior to start of radiation)
If > 1.5 mg/dL, calculated creatinine clearance >= 50 mL/min
Serum creatinine of < 2 mg/dl or creatinine clearance of > 50 cc/min
Creatinine =< 2.0 mg/dL or creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL (133 umol/L), OR if > 1.5 mg/dL: calculated creatinine clearance >= 30 mL/min
Serum creatinine =< 2.0 mg/dL (133 umol/L) OR, if > 2.0 mg/dL: calculated creatinine clearance (ClCR) >= 50 mL/min
Creatinine =< 2.0 mg/100 ml
Serum creatinine =< 1.5 mg/dl or a calculated creatinine clearance >= 60 cc/min
Must have adequate organ function as defined by the following baseline values: Absolute neutrophil count (ANC) >/=1.5x10^9/L Hemoglobin >/=9 g/dL Platelets >/=100x10^9/L Prothrombin time /International normalized ratio (INR) and partial thromboplastin time </=1.5xULN (Subjects receiving anticoagulation treatment may be allowed to participate with INR established within the therapeutic range prior to starting study treatment.) Total bilirubin </=1.5 x upper limit of normal (ULN) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) </= 2.5xULN Serum creatinine </=1.5 mg/dL (if serum creatinine is >1.5 mg/dL, calculate creatinine clearance using standard Cockcroft and Gault; creatinine clearance must be > 50 mL/min); creatinine clearance should be >/= 50 mL/min Left ventricular ejection fraction >/= institutional lower limit of normal ECHO
Serum creatinine =< 1.5 mg/dl and a creatinine clearance >= 30 ml/min
Serum creatinine < 2.5 mg/dL or creatinine clearance > 40ml/min
Subject has renal insufficiency as defined by a serum creatinine > 2.2 mg/dl or blood urea nitrogen (BUN) > 40 mg/dl (Note: If creatinine is greater than 1.5 x upper limit of normal (ULN), creatinine clearance must be greater than 60ml/min)
Inadequate renal function defined as measured creatinine clearance less than 50 mL/min/1.73 m^2 based on the Cockcroft-Gault formula (adults) or Schwartz formula (age less than or equal to 12 years). Adults: estimated creatinine clearance rate (eCCr) (mL/min/) = (140 - age) x mass (kg) x (0.85 if female)/72 x serum creatinine (mg/dL; Creatinine clearance (mL/min/1.73m^2) = eCCr x 1.73/Body Surface Area (BSA) (m^2); Children: eCCr (mL/min/1.73 m^2) = k x height (cm) / serum creatinine (mg/dL) k = 0.33 (pre-term), 0.45 (full term to 1 year old), 0.55 (age 1-12 years).
Creatinine < 2.0 mg/100 ml
Serum creatinine > 2.0 mg/dL or calculated creatinine clearance < 30 ml/min
Creatinine =< 1.5 mg/dL or creatinine clearance >= 60 ml/min
Either serum creatinine =< 1.5 mg/dL or measured creatinine clearance >= 60 mL/min
Estimated creatinine clearance >= 60 mL/min or a creatinine =< 2.2 mg/dL obtained =< 14 days prior to registration
Serum creatinine < 1.6 mg/dL or creatinine clearance >= 50 ml/min
Creatinine =< 1.5 mg/dl and creatinine clearance >= 50 ml/min/1.73 m^2
Serum creatinine =< 1.5 mg/dl; if serum creatinine is 1.2-1.5 mg/dl, the creatinine clearance (either measured or calculated) must be 50 ml/min or greater
Serum creatinine =< 1.5 mg/dl or creatinine clearance > 50 ml/min
Creatinine (Cr) < 1.5 mg/dL or creatinine clearance > 50 mL/min/m^2
Serum creatinine =< 2.0 mg/dl or creatinine clearance >= 60 mL/min
Serum creatinine =< 1.5 mg/dl and/or creatinine clearance >= 50 mL/min
Creatinine < 1.8 mg/dl (or creatinine clearance > 40 ml/min)
Serum creatinine =< 1.5 mg/dl or calculated clearance >= 50 mL/min/1.73 m^2 for patients with serum creatinine levels > 1.5 mg/dl
Serum creatinine =< 1.5 mg/dl or calculated clearance >= 50 mL/min/1.73 m^2 for patients with serum creatinine levels > 1.5 mg/dl
TREATMENT: Serum creatinine less than or equal to 1.6 mg/ml or the creatinine clearance must be greater than 70 ml/min/1.73 m^2
Serum creatinine =< 1.5 mg/dl or measured or calculated creatinine clearance >= 50 ml/min
Serum creatinine ? 2.0 mg/dL or calculated creatinine clearance of ? 60 mL/min
Patient must have adequate renal function as defined by a calculated creatinine clearance of >30 mL/min per 1.73 m[2] determined using the Schwartz equation: Creatinine clearance (ml/min per1.73 m[2]= (height [cm] x k)/ (serum creatinine [mg/dL]) where k is a standard proportionality constant based on patient's gestational age, chronologic age and gender.
Serum creatinine =< 2 mg/dL (or, if creatinine > 2 mg/dL, then a creatinine clearance of at least 35 ml/min (measured or estimated by the Cockcroft formula
Creatinine clearance > 25 mL/min or creatinine =< 1.5 mg/dL
Creatinine =< 1.5 mg/dL or creatinine clearance > 60 ml/min
Serum creatinine =< 2.0 mg/dL or creatinine clearance > 60 mL/min/1.73 m^2 for patients with creatinine levels above 2.0 mg/dL
Calculated or measured creatinine clearance >= 50 ml/min or serum creatinine =< 1.6 mg/dl
Serum creatinine <=1.5 mg/dL (If serum creatinine is >1.5 mg/dL, calculate creatinine clearance using standard Cockcroft and Gault Method Creatinine clearance must be >50 mL/min)
Serum creatinine =< 1.5 mg/dl or measured creatinine clearance of > 30 ml/min
Serum creatinine less than 1.6 mg/dl and creatinine clearance >= to 30 mL/min
Adequate renal function (serum creatinine =< 2.0 mg/dL or creatinine clearance >= 50 ml/min)
Either creatinine > 2.0 mg/dL or creatinine clearance < 30 mL/min
Serum creatinine =< 2.0 mg/dl OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 2.0
creatinine <2.0 mg/dL OR creatinine clearance >50 mL/min/1.73 m2
Chronic or acute renal insufficiency as defined by a preoperative serum creatinine greater than 1.5mg/dL or creatinine clearance of < 60 ml/min
Serum creatinine ? 2.0 mg/dL or calculated creatinine clearance ?60 mL/min
Adequate renal function, defined as Creatinine Clearance >60 mL/min or serum creatinine of ? 1.3 mg/dL (115 ?M).
Serum creatinine =< 1.5 mg/dL or calculated creatinine clearance >= 60 mL/min
Creatinine clearance > 60 mL/min/1.73 m^2 or normal age adjusted serum creatinine (=< 5 years [yrs.] =< 0.8 mg/ml; 5-10 yrs. =< 1.0 mg/ml; 10-15 yrs. =< 1.2 mg/ml; > 15 yrs. =< 1.5 mg/ml)
Creatinine clearance > 60 mL/min/1.72 m^2 or normal age adjusted serum creatinine (=< 5 yrs. =< 0.8 mg/ml; 5-10 yrs. =< 1.0 mg/ml; 10-15 yrs. =< 1.2 mg/ml; > 15 yrs. =< 1.5 mg/ml)
Creatinine clearance > 60 mL/min/1.73 m^2 or normal age adjusted serum creatinine (=< 5 yrs. =< 0.8 mg/ml; 5-10 yrs. =< 1.0 mg/ml; 10-15 yrs. =< 1.2 mg/ml; > 15 yrs. =< 1.5 mg/ml)
Creatinine =< 1.5 mg/dl and/or creatinine clearance >= 60 mL/min/1.73 m^2
Serum creatinine of <=2.0 mg/dL or creatinine clearance >=50 mL/min
Serum creatinine < 2mg/dl and calculated creatinine clearance >10ml/min.
Creatinine =< 3 mg/dL and creatinine clearance (CrCL) >= 25 ml/min
Estimated serum creatinine clearance >= 50 ml/min and/or serum creatinine =< 1.8 mg/dL
Serum creatinine less than or equal to 1.6 mg/ml or the creatinine clearance must be greater than 70 ml/min/1.73m^2
Creatinine =< 2.0 mg/dL or calculated creatinine clearance >= 40
Serum creatinine =< 3 mg/dL and creatinine clearance >= 30 ml/min
Serum creatinine =< 3 mg/dL (265 umol/L) and creatinine clearance >= 30 ml/min
Maximum serum creatinine of 1.5 mg/dL OR a creatinine clearance >= 70 ml/min/1.73m^2
Creatinine =< 1.5 mg/dl and/or creatinine clearance >= 60 mL/min
Patients must have creatinine of less than or equal to 1.5 mg/dL or creatinine clearance > 60 ml/min
Serum creatinine of < 1.5 mg/dl or calculated creatinine clearance > 50 ml/min
Serum creatinine =< 2.0 mg/dl or creatinine clearance > 60 ml/min within 90 days of enrollment
Creatinine < 1.5 mg/dL or estimated creatinine clearance >= 50 mL/min/1.73 m^2
Creatinine ?2.0 mg/dL or calculated creatinine clearance ?50 mL/min
Serum creatinine < 1.5 mg/dL or creatinine clearance >= 50 mL/min
Within 14 days prior to study entry: Serum creatinine < 1.5 mg/dl OR creatinine clearance of >= 50 cc/min
Serum creatinine =< 1.5 mg/dL (133 umol/L), or, if greater than 1.5 mg/dL: calculated creatinine clearance >= 50 mL/min (evaluated within 28 days of randomization)
Serum creatinine =< 2.0 mg/dl (calculated creatinine clearance > 45 ml/min)
Chronic or acute renal insufficiency as defined by a preoperative serum creatinine greater than 1.5 mg/dL or creatinine clearance of < 40 ml/min
Serum creatinine =< 1.3 mg/dL and creatinine clearance > 50 mL/min
serum creatinine ?1.8 mg/dL or creatinine clearance > 50 mL/min (Appendix I);
PARTICIPANTS NOT ON THE HODGKIN LYMPHOMA EXPANSION COHORT: Creatinine < 1.5 UNL or creatinine clearance (CrCl) > 50 ml/min, within 2 weeks prior to enrollment
Serum creatinine =< 1.5 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min, obtained within 4 weeks prior to randomization
Serum creatinine ? 1.5 × upper limit of normal (ULN) or creatinine clearance (CrCl) ? 40 mL/min/1.73 m2
Creatinine clearance (CrCl) >= 60 mL/min
Patients with severe renal impairment (creatinine clearance [CrCL] < 30 mL/min) are not eligible; a calculated CrCl is acceptable
CrCl ? 50 mL/min
Renal: serum creatinine ?1.5 x ULN or creatinine clearance (CrCl) ?60 mL/min as calculated by the Cockroft-Gault method
Creatinine clearance (CrCl) =< 40 mL/min
Serum creatinine =< 1.5 mg/dL OR measured creatinine clearance (CrCl) >= 45 mL/min as calculated by the Cockcroft-Gault method OR 24-hour measured urine CrCl >= 45 mL/min
CrCl (Creatinine Clearance) is >= 15 ml/min (<= 7 days prior to enrollment)
Creatinine ? 1.5 x ULN or creatinine clearance (CrCl) ? 60 mL/min
Renal: Creatinine clearance (CrCl) > 50 ml/min (measured or calculated/estimated).
Serum creatinine ?1.5x the ULN or creatinine clearance (CrCl) ?50 mL/min.
Serum creatinine (Cr) =< 1.5 X ULN or creatinine clearance (CrCl) >= 50 ml/min
Within 14 days of the first dose of study drug: Serum creatinine =< 1.5 times the upper limit of normal or estimated creatinine clearance (CrCL) > 40 mL/min
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 40 mL/min
Creatinine clearance (CrCl) >= 50 mL/min calculated by the Cockroft-Gault
Creatinine clearance (CrCl) must be > 20 mL/min
Calculated creatinine clearance (CrCl) > 30 mL/min
Calculated or measured creatinine clearance (CrCl) > 30 ml/min
Creatinine clearance (CrCl) value of >= 60 ml/min by MDRD study equation
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 40 mL/min
Serum creatinine =< 1.5 times the upper limit of normal or estimated creatinine clearance (CrCl) > 40 mL/min within 14 days of the first dose of study drug
Creatinine clearance (CrCl) > 45 mL/min
Per MDACC Creatinine clearance guidelines, patients must have a Creatinine clearance > 50 ml/min determined by 24 hour collection or nomogram: CrCl male = (140 - age) x (wt in kg)/serum Cr x 72 CrCl female = 0.85 x (CrCl male)
Serum creatinine =< 1.5 x ULN, or measured creatinine clearance (CrCl) >= 45 mL/min as calculated by the Cockcroft-Gault method or 24-hour measured urine CrCl >= 45 mL/min
Serum creatinine > 1.5 x upper limit of normal or estimated creatinine clearance (CrCl) < 45 ml/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min
Serum creatinine normal for age or calculated creatinine clearance (CrCl) >= 70 ml/min/1.73 m^2
Creatinine =< 1.5 x ULN and concurrent creatinine clearance (CrCl) >= 50 mL/min/1.73 m^2 for patients with creatinine (Cr) > 1.5 x ULN
DOSE ESCALATION COHORT: Serum creatinine ? 1.5 X ULN or creatinine clearance (CrCl) ? 50ml/min
DOSE EXPANSION COHORT: Serum creatinine ? 1.5 X ULN or CrCl ? 50 ml/min
Renal function: CrCl < 15 ml/min.
Serum creatinine =< 2.0 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min
Serum creatinine clearance (CrCl) >= 30 ml/min
Creatinine clearance (CrCL) (calculated creatinine clearance is permitted) > 40 mL/min
CrCL >= 40 ml/min
Calculated creatinine clearance (CrCl) > 30 mL/min
Renal: Serum Creatinine ? 1.5 x ULN or creatinine clearance (CrCl) ? 60 mL/min as calculated by the Cockroft-Gault method
Creatinine =< 2 x ULN or creatinine clearance (CrCl) > 30 ml/min
Patients deemed to have severe renal impairment should not be considered for this study; patients with creatinine clearance (CrCl) of < 40 mL/min should be excluded
Renal: Serum Creatinine ? 1.5 x ULN or creatinine clearance (CrCl) ? 60 mL/min as calculated by the Cockroft-Gault method
Serum creatinine =< 2 md/dL or estimated creatinine clearance (CrCl) > 50ml/min/body surface area (BSA)
Calculated creatinine clearance (CrCL) of ? 45 mL/min
Creatinine clearance (CrCl) >= 30 mL/min
Serum creatinine ? 1.5 × upper limit of normal (ULN) or creatinine clearance (CrCl) ? 40 mL/min/1.73 m
Creatinine clearance (CrCL) >= 25 ml/min
Creatinine =< 1.5 x ULN or creatinine clearance (CrCl) calculated CrCl >= 60 mL/min/1.73m^2
Creatinine =< 2 x ULN or creatinine clearance (CrCl) > 30 ml/min
Calculated or measured creatinine clearance (CrCl) of ? 30 mL/min
Creatinine clearance; calculated creatinine clearance (CrCl) >= 30 mL/min and < 60 mL/min (Cockroft-Gault) unless the patient qualified based on hearing loss or neuropathy
Calculated creatinine clearance (CRCL) > 60 mL/min
Creatinine clearance (CrCl) > 50 mL/min
Patients with severe renal impairment (creatinine clearance [CrCl] < 30 mL/min); a calculated CrCl is acceptable
Serum creatinine of ?1.5 × the upper limit of normal (ULN)OR estimated creatinine clearance (CrCl) ? 40 ml/min/1.73 m2
Previous inability to tolerate full-dose lenalidomide, adjusted to creatinine clearance (CrCl) according to Cockroft-Gault at the time of previous lenalidomide treatment (25 mg day 1-21 every 28 days if CrCl >= 60 ml/min, 10 mg lenalidomide days (d) 1-21 every 28 days if CrCl < 60 mL/min but >= 30 mL/min, lenalidomide 15 mg every 48 hours (h) d1-21 every 28 days if CrCl < 30 mL/min but not requiring dialysis, lenalidomide 5 mg daily, day 1-21 every 28 days if CrCl < 30 mL/min and requiring dialysis
Creatinine clearance (CrCl) < 30mL/min
Creatinine (Cr) =< 1.5 mg/dL x upper limit of normal (ULN), creatinine clearance (CrCl) >= 50 mL/min calculated by the Cockroft-Gault method
Serum creatinine =< 2.0 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min (drug is not cleared by the kidney)
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) of >= 30
Serum creatinine < ULN OR calculated creatinine clearance (CrCl) of ? 60 ml/min
Serum creatinine < 1.5 x upper limit of normal (ULN) or serum creatinine clearance (CrCl)> 40ml/min (CrCl= Wt (kg) x (140-age)*/72 x Cr. level, *female x 0.85)
Serum creatinine < 2 or calculated creatinine clearance (CrCl) >= 30 mL/min
Calculated or measured creatinine clearance (CrCl) >= 30 mL/min
Renal impairment at baseline as measured by serum creatinine clearance (CrCl) ?60 mL/min ?21 days prior to registration.
A measured or estimated creatinine clearance (CrCl) ?60 mL/min/1.73 m2
A calculated creatinine clearance (CrCl) that meets entry criteria for enrollment (ie, calculated CrCl either ? 90 or < 30 mL/min
CrCl ? 30 mL/min as measured by 24-hour urine
Donor must have adequate renal function as defined by a minimum creatinine clearance (CrCl) value of >30 ml/min.
Severe renal impairment: estimated creatinine clearance (CrCl) <30 ml/min, but not requiring dialysis
Normal renal function: estimated CrCl ?90 ml/min
MDRD calculated or measured CrCl of ?30 mL/min
MDRD calculated or measured CrCl of ?30 mL/min
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 40 mL/min
Serum creatinine < 1.5 mg/dl and/or calculated or measured creatinine clearance (CrCl) >= 30 ml/min
CrCL ? 40 mL/min
Creatinine > 1.5 x ULN or creatinine clearance levels (CrCL) < 45 mL/min
Estimated creatinine clearance (CrCl) >= 30 ml/min
Creatinine clearance (CrCl) < 30 ml/min
Creatinine clearance (CrCl) >= 30 milliliter per minute (mL/min)
Patients with impaired renal function creatinine clearance (CRCL) =< 60 mL/min
Creatinine =< 2 x ULN or creatinine clearance (CrCl) > 30 ml/min
Creatinine ? 1.5 x ULN or CrCl > 60 mL/min/1.73 m2 for patients with serum creatinine levels above institutional 1.5 x ULN
Measured or calculated creatinine clearance (CrCl; GFR can also be used in place of CrCl) >= 30 mL/min
Adequate renal function as demonstrated by serum creatinine ? 1.5 x ULN or 24-hour urine creatinine clearance calculation ? 60 mL/min.
Measured creatinine clearance >45 mL/minute (as assessed with a 24-hour urine collection)
Measured creatinine clearance > 60 mls/min
Creatinine clearance (Cockroft-Gault calculated or 24-hour urine) >= 30 mL/min
Creatinine OR =< 1.5 x ULN; calculated creatinine clearance OR >= 50 mL/min; 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 x ULN or a calculated creatinine clearance >= 60 ml/min/1.73 m^2 (Cockcroft-Gault method) for patients receiving combination of cisplatin and pemetrexed and >= 45 ml/min/1.73 m^2 for patients receiving pemetrexed; 24 hour urine for creatinine clearance is acceptable if the calculated creatinine clearance is insufficient
Creatinine clearance >= 40 ml/min (24 hour urine collection preferred; can be calculated if not available)
Estimated creatinine clearance >= 30 mL/min (calculated or measured by 24 hour urine collection)
Creatinine clearance (measured via 24-hour urine collection) >= 40 mL/minute (that is, if serum creatinine is > 1.5 times the ULN, a 24-hour urine collection to calculate creatinine clearance must be performed
Serum creatinine > 1.5 x upper limit of normal (ULN) and calculated creatinine clearance, based on a 24-hour urine collection, < 30 mL/min--unless related to ALL/tumor lysis syndrome and able to be corrected
Serum creatinine =< 1.5 X upper limit of normal OR creatinine clearance on a 24-hour (h) urine collection of >= 60 mL/min
Creatinine clearance of >= 50
24-hour urine creatinine clearance >= 50 mL/min, obtained within 30 days of study registration
Creatinine =< 1.5 x ULN 2 OR calculated creatinine clearance >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Measured creatinine clearance >= 40 ml/min per 24 hour urine collection OR serum creatinine =< 1.3 mg/dL
Serum creatinine =< 1.5 x upper limit of normal OR creatinine clearance on a 24-h urine collection of >= 60 mL/min
Creatinine serum =< 2.0 mg/dl or creatinine clearance >= 45 mL/min\r\n* If calculated creatinine clearance is < 45 mL/min, a 24-hour urine collection for creatinine clearance may be performed
Serum creatinine =< 2 mg/dl or creatinine clearance >= 40 ml/min (creatinine clearance calculated per Cockroft-Gault formula or by 24-hour urine collection), within 14 days prior to study entry
Patients must have a serum creatinine clearance >= 40 mL/min (as per the Jelliffe method) or by 12-hour or 24-hour urine creatinine clearance
Calculated creatinine clearance >= 40 ml/min or 24 hour urine
Creatinine =< 1.5 mg/dL or creatinine clearance >= 40 mL/min\r\n* If serum creatinine is > 1.5 times the upper limit of normal (ULN), a 24-hour urine collection to calculate creatinine clearance must be performed
Or creatinine clearance or radioisotope GFR ?50 milliliters per minute (mL/min)/1.73 meters squared (m^2) based on a 12 or 24 hour urine creatinine collection
Serum creatinine =< 1.5 x upper limit of normal OR creatinine clearance on a 24-h urine collection of >= 60 mL/min
Calculated creatinine clearance >= 40 mL/min using a serum creatinine or by 24-hour urine creatinine obtained within 28 days prior to registration
Serum creatinine =< 1.5 times upper limit of normal (ULN) OR creatinine clearance (measured via 24-hour urine collection) >= 40 mL/minute
Serum creatinine =< 1.5 mg/dL or creatinine clearance of >= 60 mL/min based on a 24-hour urine collection
Creatinine clearance (measured via 24-hour urine collection) >= 40 mL/minute (that is, if serum creatinine is > 1.5 x ULN, a 24-hour urine collection to calculate creatinine clearance must be performed)
Parts A and C: Renal function, as follows: serum creatinine ? 2.0 mg/dL, or measured 24 hour creatinine clearance of ? 45 mL/min
Creatinine ? 1.5 x ULN or 24-hour urine < Grade 2
Adequate renal function as assessed by serum creatinine ? 2.0 mg/dL; or calculated or 24-hour urine creatinine clearance >40 mL/min.
Serum creatinine =< 1.5 mg/dL OR an estimated creatinine clearance from 24 hour urine collection >= 50 ml/min
Patients must have a creatinine clearance >= 30 ml/min within 28 days of registration to be eligible for the study; this will be determined by Cockroft-Gault calculation and 24-hour urine creatinine clearance measurement (please note, renal function, measured by 24-hour urine creatinine clearance in screening and post operatively, are required)
Serum creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance >= 25 ml/min as determined by Cockroft-Gault equation or a 24 hour urine collection
Renal creatinine =< 1.5 X ULN OR calculated creatinine clearance >= 50 mL/min OR 24-hour urine creatinine clearance =< 1.5 X ULN
Subject must have adequate renal function as demonstrated by a creatinine clearance greater than or equal to 30 mL/min; determined via urine collection for 24-hour creatinine clearance or by the Cockcroft Gault formula. Note: Investigators should consider measuring a 24-hour creatinine clearance for subjects who are morbidly obese, have fluctuating renal function, or who in the investigator's clinical judgment may yield a more accurate clearance when measured than when calculated.
Calculated creatinine clearance > 40 ml/min or 24 hour urine
Creatinine clearance >= 40 ml/min (estimated or measured creatinine clearance) or serum creatinine =< 1.6 mg/dl\r\n* Random urine protein < 20 mg/dL; if >= 20 mg/dL then a 24-hour urine protein collection will be performed to accurately demonstrate that the 24-hour total is < 1000 mg, the level acceptable for enrollment on study
Within 30 days prior to initiation of protocol treatment: Creatinine serum =< 1.5 mg/dL or creatinine clearance >= 45 mL/min\r\n* If calculated creatinine clearance is < 45 mL/min, a 24-hour urine collection for creatinine clearance may be performed
Creatinine =< 1.5 times institutional upper limit of normal OR creatinine clearance >= 60ml/min/1.73m^2 measured by 24-hour urine collection
Creatinine =< 1.5 times institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 measured by 24-hour urine collection
Creatinine =< 1.5 mg/100 ml (or measured 24 hour creatinine clearance of >= 50 cc/min)
Serum creatinine < 1.6 mg/dl and/or measured creatinine clearance from 24-hour urine collection of >= 60 ml/min
Creatinine clearance < 30
Either serum creatinine >150 µmol/L (>1.7 mg/dL), or creatinine clearance <50 mL/min calculated by the Cockroft Gault method, eventually confirmed by measured creatinine clearance (or measured glomerular filtration rate (GFR) using plasma clearance methods, not gamma camera-based) <50 mL/min (the measured creatinine clearance / GFR is required only as confirmatory exam).
Creatinine < 1.5 mg/dL; if question about renal function discuss with study chairman and do 24 hour creatinine clearance (clearance should be > 50 ml/min)
Adequate renal function defined by measured creatinine clearance >= 50 mL/min by a 24-hour urine collection
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min based on a 24-hour urine collection
Creatinine clearance >= 60 ml/min as determined by 24-hour urine; if a 24-hour urine is not available, the Cockroft-Gault formula will be used for a calculated creatinine clearance
Calculated creatinine clearance >= 40 ml/min or 24 hour urine
Serum creatinine ? 1.5 x ULN, or calculated creatinine clearance ? 40 mL/min (if renal impairment is suspected 24-hour urine collection for measurement is required).
Creatinine ? 1.5 x ULN, or calculated or measured creatinine clearance ? 50 mL/min, or 24-hour measured urine creatinine clearance ? 50 mL/min.
Serum creatinine =< 1.5 x upper limit of normal OR creatinine clearance on a 24-h urine collection of >= 50 mL/min
Creatinine clearance of 50 or greater
Patients with a creatinine clearance of less than 50 are ineligible
Creatinine clearance > 40
DONOR: Creatinine clearance > 80 ml/minute as measured from a 24 hour urine collection within 26 weeks of the screening visit; if a serum creatinine drawn at the screening visit is > 20% higher than the serum creatinine drawn at the time of the 24 hour urine collection, the creatinine clearance must be re-evaluated by a repeat 24 hour urine test; if the new value is =< 80 mg/dL the donor will be excluded
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 60 mL/min based on 24-hour urine collection
Creatinine clearance >= 40 ml/min; creatinine clearance will be determined by testing of a 24 hour urine collection and simultaneous serum creatinine value
Creatinine clearance 24 hour urine creatinine clearance > 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (may use creatinine clearance Cockcroft-Gault equation)
A serum creatinine of equal or less than 2.0mg/dl or a creatinine clearance of 50 mL/min or greater on 24 hour urine collection
Individuals if creatinine clearance is < 50
Patients with a creatinine clearance less than 60
Creatinine =< 1.5 x ULN OR calculated creatinine clearance >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Creatinine =< 1.5 x ULN or creatinine clearance >= 50 mL/min using 24- hour urine collection for creatinine clearance, completed within 2 weeks prior to start of protocol therapy
Creatinine =< 1.5 X ULN OR calculated creatinine clearance >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Creatinine =< 1.5
Patients with a creatinine =< 2 x normal for age
Patients with a creatinine normal for age
Serum creatinine > 1.5 x OR creatinine clearance of at least 40
Creatinine < 2
Creatinine < or = 2
Creatinine =< 2.0
Creatinine =< 1.3
Creatinine =< 1.5
Creatinine =< 2.0
Creatinine > 3x normal
Creatinine < 1.8
Creatinine =< grade 1
Creatinine < 1.5
Creatinine < 2.0
Creatinine < 1.5
Creatinine < 2.0
Creatinine < 1.5 and creatinine clearance > 45
Creatinine < 2.0
Creatinine =< 1.5
Creatinine < 1.5
Creatinine < 2.0
Creatinine =< 1.2 x normal prior to biopsy
Creatinine =< 1.7
Normal creatinine for age
Creatinine less than 1.5
Creatinine < 2.0
Creatinine > 2.0
Creatinine > 2.0
Creatinine =< 1.3
Creatinine =< 1.5
Creatinine < 2.0
Patients with a creatinine =< 2 x normal for age
Patients with a history of renal disease or patients over 70 with a creatinine > 1.3; creatinine must have been done within the last 12 weeks
Creatinine < 1.2