[c09aa8]: / clusters / clustall / creatinine.txt

Download this file

581 lines (580 with data), 41.2 kB

  1
  2
  3
  4
  5
  6
  7
  8
  9
 10
 11
 12
 13
 14
 15
 16
 17
 18
 19
 20
 21
 22
 23
 24
 25
 26
 27
 28
 29
 30
 31
 32
 33
 34
 35
 36
 37
 38
 39
 40
 41
 42
 43
 44
 45
 46
 47
 48
 49
 50
 51
 52
 53
 54
 55
 56
 57
 58
 59
 60
 61
 62
 63
 64
 65
 66
 67
 68
 69
 70
 71
 72
 73
 74
 75
 76
 77
 78
 79
 80
 81
 82
 83
 84
 85
 86
 87
 88
 89
 90
 91
 92
 93
 94
 95
 96
 97
 98
 99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
Creatinine no greater than the institutional upper limits of normal
128.0
Serum sodium and potassium within the institutional limits of normal, within 14 days of registration and within 7 days of the start of treatment
180.0
Creatinine =< 2 x institutional upper limits of normal
42.0
Patients must have serum creatinine =< 2 x institutional upper limits of normal (IULN) within 7 days prior to registration
38.0
Creatinine within normal institutional limits OR
12.0
Cardiac function within institutional normal limits on echocardiogram
35.0
Bilirubin =< 2.0 x upper limits of normal (ULN)
420.0
Within 14 days of registration: Bilirubin =< 1.5 x upper limits of normal (ULN)
110.0
Creatinine within normal institutional limits OR
15.0
Serum bilirubin =< 1.5 x institutional upper limits of normal (ULN); must be obtained within 28 days prior to registration
180.0
Thyroid stimulating hormone (TSH) within institutional limits (ie: normal); if TSH is greater or less than institutional limits patients may participate if their T4 is within normal limits (WNL); patients may be on a stable dose of replacement thyroid medication; dose adjustments are allowed if needed
60.0
Creatinine within normal institutional limits
24.0
Creatinine =< 1.5 x ULN
102.0
Creatinine =< 1.5 x ULN obtained =< 21 days prior to registration
360.0
Serum creatinine =< grade 1
747.0
Creatinine =< grade 1
747.0
Creatinine =< 1.5 x ULN
48.0
Creatinine =< 1.5 times ULN
1120.0
Obtained =< 7 days prior to registration: Creatinine =< 1.5 x institutional ULN
102.0
Creatinine =< 1.5 x institutional ULN
113.0
Creatinine =< 1.5 x ULN
42.0
Creatinine < 1.5 x ULN
2060.0
Creatinine kinase =< 2.5 x the ULN, within 30 days prior to enrollment
278.0
Serum creatinine < 1.5 x ULN; the values must be obtained within 48 hours prior to randomization
509.0
Creatinine =< 2.0 x ULN
92.0
Serum or plasma creatinine =< 1.5 x ULN measured within 28 days prior to randomization
1500.0
Serum creatinine =< 1.5 times the ULN
44.0
Serum creatinine =< 2 x ULN
NONE
Serum creatinine =< 1.5 x ULN
450.0
Creatinine =< 1.5 x the institutional ULN
680.0
Creatinine =< 1.5 x ULN OR
82.0
Creatinine =< 1.5 x ULN OR
126.0
Serum creatinine =< 2 times ULN; timeline: within 3 weeks prior to enrollment
18.0
Serum creatinine =< 2 x ULN
714.0
Serum creatinine =< 2.0 x local institutional ULN
48.0
Creatinine =< 1.5 x ULN
22.0
Creatinine =< 1.5 x ULN OR
30.0
AST =< 2 x upper limit of normal
100.0
TREATMENT: Creatinine =< 2 x upper limit of normal for age
44.0
Creatinine =< 1.5 x upper limit of normal (ULN)
224.0
Creatinine =< 1.5 x upper limit of normal (ULN)
107.0
Creatinine =< twice upper limit institutional normal
132.0
Creatinine < 1.5 times institutional upper limit of normal, within 21 days prior to study entry
143.0
Adequate coagulation defined as:* Prothrombin time (PT) =< 1.2 x upper limit of normal
74.0
Creatinine < 1.5 institutional upper limit of normal OR
165.0
Serum creatinine of =< 1.5 X the upper limit of normal
52.0
TREATMENT: AST (SGOT)/ALT (SGPT) =< 3 x institutional upper limit of normal
700.0
Prothrombin time (PT) =< 1.5 x institutional upper limit of normal (ULN)
68.0
Prothrombin time (PT) < 1.3 x upper limit of normal (ULN)
32.0
Creatinine =< 1.5 x upper limit of normal (ULN) within 14 days prior to study registration
440.0
Serum creatinine > 2 times the upper limit of normal
125.0
Creatinine =< institutional upper limit of normal OR
40.0
Creatinine =< 1.5 x institutional/laboratory upper limit of normal (ULN)
96.0
INCLUSION CRITERIA FOR STRATUM C: ALT (SGPT) =< 3 x institutional upper limit of normal
110.0
AST/ALT =< 3 x upper limit of normal (ULN)
195.0
Creatinine (Cr) < 1.5 upper limit of normal (ULN)
23.0
Creatinine =< 1.5 x institutional upper limit of normal
35.0
Creatine phosphokinase =< institutional upper limit of normal
37.0
AST (SGOT)/ALT(SGPT) (only if elevated liver function tests [LFTs] are due to disease) =< 5.0 x institutional upper limit of normal
36.0
Serum creatinine =< 1.5 x upper limit of normal (ULN)
64.0
Creatinine =< 1.5 x upper limit of normal (ULN)
137.0
Serum creatinine of =< 1.5 x the upper limit of normal
24.0
Creatinine =< 1.5 x upper limit of normal (ULN)
84.0
Note: ULN is institutional or laboratory upper limit of normal
84.0
Creatinine =< 1.5 x upper limit of normal (ULN) or
124.0
Within 14 days prior to registration: Creatinine =< 1.5 x institutional upper limit of normal (ULN)
488.0
Creatinine =< 1.5 x upper limit of normal (ULN) or
700.0
Sodium >= the institutional lower limit of normal
30.0
AST =< 8 x upper limit of normal (ULN)
324.0
Serum creatinine =< 1.5 mg/dL within 14 days prior to study entry
285.0
If the patient is to be treated with cisplatin, the serum creatinine should be =< 1.5 mg%
37.0
Serum creatinine =< 2 mg/dL
100.0
Creatinine =< 1.5 mg/dL
40.0
Serum creatinine level =< IULN within 28 days prior to registration
1900.0
Serum creatinine =< 1.5 x IULN obtained within 28 days prior to registration
491.0
Serum creatinine of =< 1.5 mg/dL; if creatinine > 1.5 mg/dL, creatinine clearance must be >= 60 mL/minute
70.0
Serum creatinine < 2.0 mg/dl
252.0
Obtained =< 48 hours prior to registration: Serum creatinine =< 2.0 mg/dl
509.0
Creatinine less than 1.4 mg/dl
540.0
Creatinine =< 2.0 mg/dL
63.0
Creatinine =< 2.0 mg/dL
600.0
Patients must have serum creatinine =< 1.5 mg/dl within 14 days prior to registration
44.0
Serum creatinine =< 1.5 mg/dl within 14 days prior to registration
44.0
Registration Step 3 � Maintenance: Patients must have serum creatinine =< 1.5 mg/dl within 14 days prior to registration
44.0
Patients with serum creatinine > 3.0 mg/dL and patients on active dialysis for renal dysfunction are excluded
158.0
Within 14 days of registration: Serum creatinine < 2.0 mg/dL (176.8 umol/liter)
110.0
Within 14 days of registration: Serum calcium =< 11.5 mg/dL
110.0
Serum creatinine =< IULN within 14 days prior to registration
150.0
Creatinine =< 2.0 mg/dL
50.0
Creatinine < 1.5 mg/dl (= 132 umol/L) or
46.0
Creatinine < 1.7 mg/dL
130.0
Patients must have adequate renal function with serum creatinine level =< IULN within 21 days prior to registration
333.0
Within 14 days prior to registration: Serum creatinine =< 2.0 mg/dL
143.0
Within 28 days prior to registration: Serum creatinine =< 2.0 x IULN
707.0
Serum creatinine < 2.0 x IULN within 28 days prior to registration
64.0
Creatinine < 2 mg/dl
186.0
Creatinine =< 1.6 mg/dl
50.0
Serum creatinine =< 2.0 x IULN within 28 days prior to registration
94.0
Serum creatinine < 1.5 mg/dl
120.0
Serum creatinine < 2 x institutional ULN or; creatinine clearance (CC) >= 50 mL/min determined by 24-hour collection or estimated by Cockcroft-Gault formula
700.0
Patients must have a serum creatinine =< the IULN AND measured or calculated creatinine clearance >= 60 cc/min using the Cockroft-Gault formula
162.0
REGISTRATION #2 - PRIOR TO CONSOLIDATION CHEMOTHERAPY: Patients must have a serum creatinine =< (IULN) AND measured of calculated creatinine clearance >= 60 cc/min using the Cockroft-Gault formula
162.0
Creatinine clearance (CrCL) >= 30 mL/min, measured by a 24-hour urine collection or estimated by the Cockcroft and Gault formula within 14 days prior to registration
130.0
Serum creatinine institutional ULN within 14 days prior to registration or; creatinine clearance (CC) >= 50 ml/min within 14 days prior to registration determined by 24-hour collection or estimated by Cockcroft-Gault formula
660.0
Serum creatinine < 1.5 mg/dL or calculated creatinine clearance >= 50 ml/min (by Cockcroft-Gault formula) within 14 days prior to registration
234.0
Calculated creatinine clearance by Cockcroft-Gault formula >= 30 ml/min obtained within 2 weeks prior to registration
189.0
RANDOMIZED PHASE II (ARMS K AND L): Calculated creatinine clearance by Cockroft-Gault formula >= 30 ml/min, obtained within 2 weeks prior to registration
189.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
30.0
Calculated (Calc.) creatinine clearance >= 30 mL/min; calculated utilizing the Cockcroft-Gault formula or 24-hour urine collection
97.0
RE-REGISTRATION ELIGIBILITY CRITERIA (STEP 2): Calc. creatinine clearance >= 30 mL/min* Calculated utilizing the Cockcroft-Gault formula or 24-hour urine collection
97.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min
40.0
Serum creatinine < 1.5 mg/dL or calculated creatinine clearance >= 50 mL/min within 30 days prior to registration estimated by the Cockcroft-Gault formula
330.0
Serum creatinine =< 1.5 mg/dL (=< 133 umol/L) OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
68.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
130.0
Serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min using the following Cockcroft-Gault Formula within 28 days prior to sub-study registration
10000.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
250.0
Serum creatinine =< 1.5 mg/dl or calculated creatinine clearance (CC) >= 50 ml/min determined by 24-hour urine collection or estimated by Cockcroft-Gault formula, within 21 days prior to registration
924.0
Calculated creatinine clearance >= 60 mL/min; the serum creatinine value used in the calculation must have been obtained within 28 days prior to registration; use the modified Cockcroft-Gault formula
230.0
Creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
35.0
Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula, must be obtained within 8 weeks prior to screening for protocol therapy
562.0
ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula
562.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min
18.0
Patients must have a creatinine clearance >= 30 ml/min within 28 days of registration to be eligible for the study; this will be determined by Cockroft-Gault calculation and 24-hour urine creatinine clearance measurement (please note, renal function, measured by 24-hour urine creatinine clearance in screening and post operatively, are required)
60.0
Creatinine =< 2.0 mg/dL OR creatinine clearance (calculated clearance permitted) >= 40 mL/min by Cockcroft-Gault formula
302.0
Creatinine =< 1.5 mg/dL to receive weekly cisplatin* Patients whose serum creatinine is between 1.5 and 1.9 mg/dL are eligible for cisplatin if the estimated creatinine clearance (CCr) is >= 30 ml/min; for the purpose of estimating the CCr, the formula of Cockcroft and Gault for females should be used
188.0
Creatinine clearance >= 60 mL/min by the modified Cockcroft-Gault formula; timeline: within 3 weeks prior to enrollment
18.0
Calculated creatinine clearance must be > 60 ml/min using the Cockcroft-Gault formula within 4 weeks prior to randomization
345.0
Estimated creatinine clearance (CrCl) >= 50 mL/min/1.73 m^2 according to the Cockcroft-Gault formula, within 14 days prior to registration
147.0
Creatinine clearance (CrCl) >= 50 ml/min within 14 days prior to registration as determined by 24-hour collection or estimated by Cockcroft-Gault formula
56.0
Within 28 days prior to registration: Creatinine clearance (CrCl) >= 50 mL/min., as estimated by the Cockcroft and Gault formula; estimated creatinine clearance is based on actual body weight
707.0
Within 28 days prior to administration of study treatment: Creatinine clearance >= 51 mL/min, calculated using Cockcroft-Gault formula
90.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
68.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
21.0
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min within 30 days of day 1 of study
27.0
Serum creatinine =< 1.5 times ULN OR calculated creatinine clearance >= 70 mL/min
729.0
Creatinine =< 1.5 x ULN OR calculated or measured creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine above institutional normal
36.0
Creatinine =< upper limit of normal (ULN) or calculated creatinine clearance >= 60 mL/min
360.0
Creatinine =< 1.5 times institutional upper limit of normal (ULN) OR calculated creatinine clearance >= 60 mL/min
52.0
Serum creatinine =< 1.2 x ULN or creatinine clearance >= 60 mL/min; obtained within 14 days prior to study entry
368.0
STEP I: Calculated creatinine clearance >= 30 mL/min (obtained within 28 days prior to randomization)
1080.0
Serum creatinine =< 1.5 mg/dL OR measured or calculated creatinine clearance >= 50 mL/min
97.0
Serum creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2
68.0
Serum creatinine =< 1.5 mg/dL OR creatinine clearance >= 50 mL/min/1.73 m^2
32.0
Serum creatinine =< 1.5 x mg/dL OR measured or calculated creatinine clearance >= 50 mL/min; creatinine measurements must be obtained within 28 days prior to registration
280.0
Calculated (calc.) creatinine clearance >= 50 mL/min* Estimated creatinine clearance for patients >= 18 years old will be estimated by the Jelliffe equation modified for body surface area (BSA); patients with creatinine clearance estimated > 70ml/min by this formula are eligible; if the creatinine clearance estimated by the Jelliffe method is >= 50 mL/min but =< 70 mL/min, then a second method to confirm a creatinine clearance of >= 50 mL/min is required; methods of estimating glomerular filtration rate (GFR) that can be used for this confirmation consist of a 12 or 24-hour urine creatinine clearance or a nuclear creatinine clearance test; if the confirmatory creatinine clearance is < 50 mL/min, then the patient is not eligible; if the confirmatory creatinine clearance is >= 50 mL/min, the patient is eligible; if the cause of the patient�s renal dysfunction is tumor obstructing the ureters, then eligibility can be determined by the study chair even if it does not meet these minimal requirements; for patients < 18 years old, it is strongly suggested that a radioisotope estimation of GFR be obtained; if a radioisotope test is not possible, an estimated creatinine clearance using either a 12 or 24 hour urine creatinine clearance or the Schwartz formula can be used; patients will be considered eligible if the creatinine clearance is > 70 mL/min; if the creatinine clearance estimated by the Schwartz formula or urine creatinine clearance is >= 50 mL/min but =< 70 mL/min, then a second method to confirm a creatinine clearance of >= 50 mL/min is required; methods of estimating GFR that can be used for this confirmation consist of a 12- or 24-hour urine creatinine clearance if the Schwartz formula or radioisotope method was used as the primary method or a radioisotope estimation of GFR if the Schwartz formula or urine creatinine clearance method was used as the primary method; if the confirmatory creatinine clearance is < 50 mL/min, then the patient is not eligible; if the confirmatory creatinine clearance is >= 50 mL/min, the patient is eligible
420.0
Serum creatinine =< 1.5 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min, obtained within 4 weeks prior to randomization
300.0
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 40 ml/min/1.73 m^2 unless lymphoma related
52.0
Serum creatinine =< 1.5 X ULN or measured or calculated creatinine clearance (CrCl) >= 60 mL/min for subject with creatinine levels > 1.5 X institutional ULN (glomerular filtration rate [GFR] can also be used in place of creatinine or CrCl); creatinine clearance should be calculated per institutional standard
36.0
For patients who have creatinine clearance that meets > 50 ml/min they must not have received prior systemic doxorubicin
60.0
Obtained within 28 days prior to registration: Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 60 mL/min
223.0
Serum creatinine =< 1.5 x upper limit of normal (ULN) or serum creatinine clearance (CrCl) >= 40 ml/min
400.0
Serum creatinine =< 3 mg/dL (265 umol/L) and creatinine clearance >= 30 ml/min
510.0
Serum creatinine =< 1.5 x ULN or a calculated creatinine clearance >= 60 ml/min/1.73 m^2 (Cockcroft-Gault method) for patients receiving combination of cisplatin and pemetrexed and >= 45 ml/min/1.73 m^2 for patients receiving pemetrexed; 24 hour urine for creatinine clearance is acceptable if the calculated creatinine clearance is insufficient
58.0
Adequate renal function determined within 6 weeks prior to randomization defined as the most recent serum creatinine =< ULN or measured or calculated creatinine clearance > 60 mL/min
990.0
Creatinine clearance >= 50 mL/min
82.0
Creatinine clearance >= 50 mL/min
50.0
Serum creatinine must be =< 2 x the institutional ULN OR creatinine clearance (either measured or calculated) must be > 30 mL/min; must be obtained within 28 days prior to registration
180.0
Serum creatinine < 2.5 X institutional ULN OR measured or calculated* creatinine clearance (CrCl) (glomerular filtration rate [GFR] can also be used in place of creatinine or CrCl) >= 30 mL/min for subject with creatinine levels > 2.5 X institutional ULN* Creatinine clearance should be calculated per institutional standard
60.0
Creatinine clearance >= 60 mL/min/1.73 m^2
51.0
CLINICAL/LABORATORY CRITERIA: Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 40 mL/min; this result must have been obtained within 28 days prior to registration
53.0
Serum creatinine =< ULN for the lab and measured or calculated creatinine clearance > 60 mL/min within 28 days before randomization
348.0
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 40 mL/min, within 4 weeks of randomization
766.0
Serum creatinine =< 1.5 ULN OR measured or calculated creatinine clearance >= 30 mL/min
148.0
Within 28 days prior to administration of therapy: Creatinine clearance >= 50 mL/min
132.0
Calculated creatinine clearance > 70 mL/min/1.73 m^2
40.0
Calculated creatinine clearance by Modification of Diet in Renal Disease (MDRD) (CrCl) >= 60 ml/min/1.73 squared meter
27.0
Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min, obtained within 28 days prior to step 2 registration
1000.0
Creatinine clearance >= 60 mL/min/1.73 m^2
30.0
Calculated creatinine clearance >= 45 mL/min/1.73 m^2
47.0
Patients must have adequate renal function as documented by a calculated creatinine clearance >= 60 mL/min, within 28 days prior to registration
150.0
Creatinine =< institutional upper limit normal (ULN), CTCAE v 3.0 grade 0; NOTE: if creatinine > ULN, creatinine clearance must be > 50 mL/min
164.0
Creatinine < 1.5 x ULN OR creatinine clearance measured >= 60 mL/minute for patients with creatinine levels >= 1.5 x upper limit of normal
74.0
Creatinine =< 1.5 times institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2
130.0
Obtained within 30 days of registration: Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
24.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
55.0
Creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 x institutional upper limit of normal
165.0
Creatinine clearance >= 50 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
42.0
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
36.0
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
140.0
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
72.0
Creatinine < 1.5 X institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels above 1.5 X institutional upper limit of normal
68.0
Serum creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal, as determined by a measured 24-hour creatinine clearance
80.0
Creatinine < 1.5 x upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels >= 1.5 x upper limit of normal
72.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal
70.0
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
72.0
TUMOR BIOPSY SEQUENCING: Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels >= 1.5 x institutional upper limit of normal
700.0
TREATMENT: Creatinine < 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels >= 1.5 x institutional upper limit of normal
700.0
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
12.0
Creatinine =< 1.5 � institutional upper limit of normal OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional limit of normal
100.0
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
24.0
Creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels > 1.5 mg/dL
35.0
Creatinine within normal institutional limits or creatinine clearance >= 60mL/min/1.73 m^2 for subject with creatinine levels above institutional normal
182.0
Creatinine clearance >= 50 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
40.0
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min for patients with creatinine levels above institutional normal
57.0
Creatinine < 1.5 x normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine level above institutional normal based either on Cockroft-Gault estimate or based on urine collection (12 or 24 hour)
23.0
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (Cockcroft formula)
90.0
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
23.0
Creatinine =< 1.5 x upper limit of normal OR creatinine clearance >= 50 mL/min
66.0
Creatinine within normal institutional limit for the reference lab OR creatinine clearance >= 60 mL/min/1.73 m^2 as calculated by Cockcroft-Gault formula for participants with creatinine levels above institutional normal
42.0
Within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration: Creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
6452.0
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
35.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
30.0
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73 m^2 for patients with creatinine levels above institutional normal
75.0
Creatinine =< upper limit of normal institutional limits or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
50.0
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
30.0
Creatinine =< the institutional upper limit of normal (ULN) OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
549.0
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional normal
46.0
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min for patients with creatinine levels above institutional normal
33.0
Creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
126.0
Creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
46.0
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
15.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
46.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
45.0
Creatinine =< 1.5 x ULN or a creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
50.0
Creatinine within normal institutional limits for age OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above ULN
46.0
Within 2 weeks prior to initiation of study treatment: Creatinine =< upper limit of institutional normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
70.0
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
150.0
Creatinine =< 1.5 x ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
48.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
20.0
Creatinine levels =< upper limit of institutional normal; or creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal
36.0
Creatinine =< 1.5 X institutional upper limit of normal or creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
60.0
Serum creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with serum creatinine levels > 1.5 x higher than institutional normal
38.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
70.0
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
24.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
24.0
Creatinine =< the institutional upper limit of normal OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
40.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
70.0
Creatinine =< institutional upper limit of normal OR creatinine clearance >= 60 ml/min/1.73m^2 for patients with creatinine levels above institutional normal
35.0
Creatinine =< 1.5 mg/dL OR calculated (calc.) creatinine clearance >= 30 mL/min
34.0
Creatinine =< 1.5 x upper limit of normal (ULN) mg/dL OR calculated (calc.) creatinine clearance >= 60 mL/min
20.0
Creatinine =< 1.5 mg/dL x upper limits of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
30.0
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min using the lean body mass formula only
195.0
Re-registration: creatinine =< 1.5 ULN OR calc. creatinine clearance > 45 mL/min (using lean body mass formula only)
195.0
Within 14 days of registration: Calculated (calc.) creatinine clearance > 50 mL/min
110.0
Creatinine OR =< 1.5 mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min
69.0
Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance >= 30 mL/min
45.0
Calculated (calc.) creatinine clearance > 45 mL/min
124.0
Calculated (calc.) creatinine clearance >= 50 mL/min by Cockcroft-Gault
324.0
Glomerular filtration rate (GFR) > 25 ml/min (for patients receiving cisplatin, GFR >= 60 ml/min)
37.0
Patients with a serum creatinine > 1 are eligible if they have a calculated glomerular filtration rate (GFR) of >= 60 ml/min (i.e. class I or class II chronic kidney disease ) using the Modification of Diet in Renal Disease (MDRD) formula* Note: Daily creatinine and MDRD formula are only for the 1st induction cycle
747.0
Creatinine clearance or estimated radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
74.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
77.0
Estimated glomerular filtration rate (GFR) (calculated using Chronic Kidney Disease Epidemiology Collaboration [CKD-EPI] equation) >= 30 mL/min/1.73 sq.m.
54.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
81.0
Creatinine within normal limits for the laboratory OR creatinine clearance >= 60 mL/min/1.73 m^2 (estimated glomerular filtration rate [eGFR]) for patients with creatinine levels above the ULN for the laboratory
30.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
44.0
Creatinine clearance >= 50 mL/min by either measured (using the Cockcroft-Gault, Modification of Diet in Renal Disease [MDRD] or Chronic Kidney Disease Epidemiology [CKD-EPI] formula) or calculated clearance (i.e. glomerular filtration rate [GFR])
90.0
Creatinine clearance estimated glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2 (Cockcroft-Gault)
32.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or
53.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2
700.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2
1680.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
49.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or
98.0
Estimated creatinine clearance of > 50 ml/min (0.84 mL/s) by the Cockcroft-Gault equation
90.0
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above ULN as calculated by Cockcroft-Gault
110.0
Serum creatinine calculated creatinine clearance by the method of Cockcroft and Gault (< 50mL/min)
45.0
Creatinine clearance >= 60 mL/min by the Cockcroft-Gault equation
80.0
Blood creatinine =< 1.5 mg/dL (if blood creatinine is > 1.5 mg/dL, calculate creatinine clearance using standard Cockcroft and Gault method or using a 24 hour urine collection for creatinine; creatinine clearance must be > 50 mL/min), within 2 weeks of the first dose of study treatment
18.0
Serum creatinine =< 1.5 x ULN OR creatinine clearance (CrCl) >= 50 mL/min (if using the Cockcroft-Gault formula)
80.0
Creatinine =< 1.5 x ULN OR creatinine clearance >= 40 mL/min/1.73 m^2 (calculated using the Chronic Kidney Disease-Epidemiology Collaboration [CKD-EPI] equation or Cockroft-Gault formula) for patients with creatinine levels above institutional normal
135.0
Serum creatinine =< 1.5 x ULN OR creatinine clearance (CrCl) >= 50 mL/min (if using the Cockcroft-Gault formula)
37.0
Creatinine =< 1.5 mg/dl OR creatinine clearance >= 55 mL/min using the Cockcroft-Gault equation for patients with creatinine levels above 1.5 mg/dl
12.0
Creatinine =< 1.5 x upper normal institutional limits (UNL) OR creatinine clearance >= 40 mL/min based either on Cockcroft-Gault estimate or based on urine collection (12 or 24 hour)
209.0
Serum creatinine =< 1.5 X institutional ULN and creatinine clearance >= 60 ml/min* NOTE: creatinine clearance must be calculated using the Cockcroft-Gault equation
126.0
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min using the modified Cockcroft-Gault formula
45.0
Creatinine < 1 X institutional upper limit of normal OR creatinine clearance >= 50 mL/min determined by Cockcroft-Gault formula
37.0
Calculated creatinine clearance of > 50 mL/min using Cockcroft Gault equation equation or 24-hour urine sampling
36.0
Body surface area (BSA)-normalized creatinine clearance >= 60 mL/min/1.73 m^2 (using Cockcroft-Gault creatinine clearance [CrCl])
36.0
Creatinine =< 1.5 x ULN OR creatinine clearance (CrCl) >= 50 mL/min (if using the Cockcroft-Gault formula)
29.0
Creatinine clearance >= 30 mL/min/1.73 m^2 by Cockcroft-Gault
35.0
Creatinine clearance >= 51 mL/min/1.73 m^2 by Cockcroft-Gault
72.0
Creatinine clearance >= 30 mL/min/1.73 m^2 by Cockcroft-Gault
40.0
Serum creatinine =< 1.5 x ULN OR creatinine clearance (CrCl) >= 50 mL/min (if using the Cockcroft-Gault formula)
30.0
Creatinine clearance >= 30 mL/min/1.73 m^2 by Cockcroft-Gault
60.0
Measured creatinine clearance (CL) > 40 mL/min OR calculated creatinine clearance (CL) > 40 mL/min as determined by Cockcroft-Gault (using actual body weight)
180.0
Within less than or equal to 14 days prior to registration: Serum creatinine =< 1.5 X institutional ULN and creatinine clearance >= 60 ml/min* NOTE: Creatinine clearance must be calculated using the Cockcroft-Gault equation
40.0
Calculated creatinine clearance >= 45 mL/min by Cockcroft-Gault equation
700.0
Serum creatinine > 1.5 times ULN concurrent with creatinine clearance < 50 mL/min (measured or calculated by Cockcroft and Gault equation)�confirmation of creatinine clearance is only required when creatinine is > 1.5 times ULN
98.0
Creatinine clearance >= 30 mL/min/1.73 m^2 by Cockcroft-Gault
78.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 60 ml/min/1.73 m^2 or a normal serum creatinine based on age described in the table below:* Age: =< 5 years; maximum serum creatinine: 0.8 mg/dL* Age: 5 < age =< 10 years; maximum serum creatinine: 1.0 mg/dL* Age: 10 < age =< 15 years; maximum serum creatinine: 1.2 mg/dL* Age: > 15 years; maximum serum creatinine: 1.5 mg/dL
104.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age: 11 to < 13 years old; 1.2 (male, female) maximum serum creatinine (mg/dL)* Age: 13 to < 16 years old; 1.5 (male), 1.4 (female) maximum serum creatinine (mg/dL)* Age: >= 16 years old; 1.7 (male), 1.4 (female) maximum serum creatinine (mg/dL)
90.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 mL/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* 2 to < 6 years of age** Male and female: 0.8 (maximum serum creatinine [mg/dL])* 6 to < 10 years of age** Male and female: 1 (maximum serum creatinine [mg/dL])* 10 to < 13 years of age** Male and female: 1.2 (maximum serum creatinine [mg/dL])* 13 to < 16 years of age** Male 1.5 (maximum serum creatinine [mg/dL])** Female: 1.4 (maximum serum creatinine [mg/dL])* >= 16 years of age** Male: 1.7 (maximum serum creatinine [mg/dL])** Female: 1.4 (maximum serum creatinine [mg/dL])
146.0
A serum creatinine based on age/gender as follows:* 1 to < 2 years: maximum serum creatinine 0.6 mg/dL (both male and female)* 2 to < 6 years: maximum serum creatinine 0.8 mg/dL (both male and female)* 6 to < 10 years: maximum serum creatinine 1 mg/dL (both male and female)* 10 to < 13 years: maximum serum creatinine 1.2 mg/dL (both male and female)* 13 to < 16 years: maximum serum creatinine 1.5 mg/dL (male), 1.4 mg/dL (female)* >= 16 years: maximum serum creatinine 1.7 mg/dL (male), 1.4 mg/dL (female)
53.0
Serum creatinine within normal limits based on age/gender, as follows:* 1 to < 2 years: maximum serum creatinine 0.6 mg/dL (both male and female)* 2 to < 6 years: maximum serum creatinine 0.8 mg/dL (both male and female)* 6 to < 10 years: maximum serum creatinine 1 mg/dL (both male and female)* 10 to < 13 years: maximum serum creatinine 1.2 mg/dL (both male and female)* 13 to < 16 years: maximum serum creatinine 1.5 mg/dL (male), 1.4 mg/dL (female)* >= 16 years: maximum serum creatinine 1.7 mg/dL (male), 1.4 mg/dL (female)
700.0
A serum creatinine based on age/gender as follows:* Age 1 to < 2 years: maximum serum creatinine 0.6 mg/dL for male and 0.6 mg/dL for female* Age 2 to < 6 years: maximum serum creatinine 0.8 mg/dL for male and 0.8 mg/dL for female* Age 6 to < 10 years: maximum serum creatinine 1 mg/dL for male and 1 mg/dL for female* Age 10 to < 13 years: maximum serum creatinine 1.2 mg/dL for male and 1.2 mg/dL for female* Age 13 to < 16 years: maximum serum creatinine 1.5 mg/dL for male and 1.4 mg/dL for female* Age >= 16 years: maximum serum creatinine 1.7 mg/dL for male and 1.4 mg/dL for female
49.0
A serum creatinine based on age/gender as follows:* Age 1 to < 2 years: maximum serum creatinine 0.6 mg/dL for male and 0.6 mg/dL for female* Age 2 to < 6 years: maximum serum creatinine 0.8 mg/dL for male and 0.8 mg/dL for female* Age 6 to < 10 years: maximum serum creatinine 1 mg/dL for male and 1 mg/dL for female* Age 10 to < 13 years: maximum serum creatinine 1.2 mg/dL for male and 1.2 mg/dL for female* Age 13 to < 16 years: maximum serum creatinine 1.5 mg/dL for male and 1.4 mg/dL for female* Age >= 16 years: maximum serum creatinine 1.7 mg/dL for male and 1.4 mg/dL for female
98.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age: 1 to < 2 years; maximum serum creatinine (mg/dL): male 0.6; female 0.6* Age: 2 to < 6 years; maximum serum creatinine (mg/dL): male 0.8; female 0.8* Age: 6 to < 10 years; maximum serum creatinine (mg/dL): male 1; female 1* Age: 10 to < 13 years; maximum serum creatinine (mg/dL): male 1.2; female 1.2* Age: 13 to < 16 years; maximum serum creatinine (mg/dL): male 1.5; female 1.4* Age: >= 16 years; maximum serum creatinine (mg/dL): male 1.7; female 1.4
49.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age: 1 to < 2 years; maximum serum creatinine (mg/dL): male 0.6; female 0.6* Age: 2 to < 6 years; maximum serum creatinine (mg/dL): male 0.8; female 0.8* Age: 6 to < 10 years; maximum serum creatinine (mg/dL): male 1; female 1* Age: 10 to < 13 years; maximum serum creatinine (mg/dL): male 1.2; female 1.2* Age: 13 to < 16 years; maximum serum creatinine (mg/dL): male 1.5; female 1.4* Age: >= 16 years; maximum serum creatinine (mg/dL): male 1.7; female 1.4
144.0
Creatinine clearance or radioisotope glomerular filtration rate (GFR) within 7 days prior to enrollment >= 70 ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age: 1 to < 2 years; maximum serum creatinine (mg/dL): male 0.6; female 0.6* Age: 2 to < 6 years; maximum serum creatinine (mg/dL): male 0.8; female 0.8* Age: 6 to < 10 years; maximum serum creatinine (mg/dL): male 1; female 1* Age: 10 to < 13 years; maximum serum creatinine (mg/dL): male 1.2; female 1.2* Age: 13 to < 16 years; maximum serum creatinine (mg/dL): male 1.5; female 1.4* Age: >= 16 years; maximum serum creatinine (mg/dL): male 1.7; female 1.4
49.0
GENERAL INCLUSION CRITERIA FOR SUBPROTOCOLS: Creatinine clearance or radioisotope glomerular filtration rate (GFR) >= 70ml/min/1.73 m^2 or a serum creatinine based on age/gender as follows:* Age: 1 to < 2 years; maximum serum creatinine (mg/dL): male 0.6; female 0.6* Age: 2 to < 6 years; maximum serum creatinine (mg/dL): male 0.8; female 0.8* Age: 6 to < 10 years; maximum serum creatinine (mg/dL): male 1; female 1* Age: 10 to < 13 years; maximum serum creatinine (mg/dL): male 1.2; female 1.2* Age: 13 to < 16 years; maximum serum creatinine (mg/dL): male 1.5; female 1.4* Age: >= 16 years; maximum serum creatinine (mg/dL): male 1.7; female 1.4
1500.0