Platelets (PLT) >= 100,000/mcL 36.0 Platelets >= 100,000/mcL 102.0 Platelets >= 100,000/mcl 360.0 Platelets >= 100,000/mcL 276.0 Platelets >= 100,000/mcl 162.0 Platelets >= 100,000/mcL 40.0 Platelets >= 100,000/mcL 107.0 Platelets >= 100,000/mcl 52.0 Platelets >= 100,000/mcL 55.0 Platelets >= 100,000/mcL 165.0 Platelets >= 100,000/mcL 42.0 Platelets >= 100,000/mcL 36.0 Platelets >= 100,000/mcL 140.0 Platelets >= 100,000/mcL 80.0 Platelets >= 100,000/mcL 68.0 Platelets >= 75,000/mcL 42.0 Platelets >= 100,000/mcL 73.0 Platelets >= 100,000/mcL 80.0 Platelets >= 100,000/mcL 70.0 Platelets >= 100,000/mcL 72.0 Platelets >= 100,000/mcL (without transfusion) 12.0 Platelets >= 100,000/mcL 68.0 Platelets greater than or equal to 100,000/mcl 540.0 Platelets >= 50,000/mcL 54.0 Platelets >= 100,000/mcL 32.0 Platelets >= 100,000/mcL 100.0 Platelets >= 100,000/mcL 24.0 Platelets >= 100,000/mcL 35.0 Platelets >= 100,000/mcL 230.0 Platelets >= 100,000/mcL 40.0 Platelets >= 100,000/mcL 57.0 Platelets >= 50,000 cells/mcL (50 x 10^9/L) 52.0 Platelets >= 100,000/mcL 90.0 Platelets >= 100,000/mcL 36.0 Platelets >= 100,000/mcL 23.0 Platelets >= 50,000/mcL or recovery to the baseline count 80.0 Platelets >= 75,000/mcL 135.0 Platelets >= 100,000/mcL 37.0 Platelets >= 150,000/mcL 66.0 Platelets >= 50,000/mcL 12.0 Platelets >= 100,000/mcL 42.0 Platelets >= 100,000/mcL 209.0 Platelets >= 100,000/mcL 30.0 Platelets >= 100,000/mcL 75.0 Platelets >= 100,000/mcL (not requiring platelet transfusions) 50.0 Platelets >= 100,000/mcL 30.0 Platelets >= 100,000/mcL 549.0 Platelets >= 100,000/mcL 680.0 Platelets >= 100,000/mcL 46.0 Platelets >= 100,000/mcL 45.0 Platelets >= 100,000/mcL 82.0 Platelets >= 100,000/mcL 126.0 Platelets >= 100,000/mcL 150.0 Platelets >= 100,000/mcL 50.0 Platelets >= 75,000/mcL 46.0 Platelets >= 100,000/mcL 15.0 Platelets >= 100,000/mcL 46.0 Platelets >= 50,000/mcL 36.0 Platelets >= 100,000/mcL 90.0 Platelets >= 100,000/mcL 45.0 Platelets >= 75,000/mcL, unless due to marrow involvement by lymphoma in which case a platelet count of >= 30,000/mcL will be used 50.0 Platelets >= 100,000/mcL 46.0 Platelets > 50,000/mcL 60.0 Within 2 weeks prior to initiation of study treatment: Platelets >= 100,000/mcL 70.0 Platelets >= 100,000/mcL (without transfusion within 2 weeks prior to cycle 1, day 1) 29.0 Platelets >= 100,000/mcL 51.0 Platelets >= 100,000/mcL 150.0 Platelets >= 100,000/mcL 48.0 Platelets >= 100,000/mcL 20.0 Platelets >= 75,000/mcl 84.0 Platelets >= 100,000/mcL 60.0 Platelets >= 100,000/mcL 38.0 Platelets >= 100,000/mcL 70.0 Platelets >= 100,000/mcL 24.0 Platelets >= 100,000/mcL 35.0 Platelets >= 100,000/mcL (not requiring platelet transfusions) 24.0 Platelets >= 100,000/mcL 28.0 Platelets >= 100,000/mcL 148.0 Platelets >= 100,000/mcL 72.0 Platelets >= 75,000/mcL (>= 50,000 for patients with hematologic malignancies) 40.0 Platelets >= 150,000/mcL 60.0 Platelets >= 100,000/mcL 180.0 Platelets >= 100,000/mcL 40.0 Platelets >= 100,000/mcL 22.0 Platelets >= 100,000/mcL 70.0 Platelets >= 100,000/mcL 47.0 Platelets >= 100,000/mcL 35.0 Platelets >= 100,000/mcL 78.0 Platelet count: >= 50,000/mm^3, transfusion independent (no platelet transfusions within 1 week) 62.0 Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 77.0 For patients with solid tumors without known bone marrow involvement: platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 154.0 Platelets >= 100,000/mm^3 transfusion independent (no platelet transfusion one week prior to enrollment) 40.0 Platelet count >= 75,000 and transfusion independent 28.0 For patients with solid tumors without known bone marrow involvement: platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 148.0 Platelet count >= 75,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 484.0 * Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 81.0 Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 67.0 For patients with solid tumors without known bone marrow involvement: * Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 75,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment)* Hemoglobin >= 8.0 g/dl at baseline (may receive packed red blood cell [PRBC] transfusions) 65.0 Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 36.0 Platelet count >= 100,000/uL (transfusion independent, defined as not receiving platelet transfusions within a 7 day period prior to enrollment) for patients with solid tumors without bone marrow involvement 146.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment)* Hemoglobin >= 8.0 g/dl at baseline (may receive red blood cell [RBC] transfusions) 51.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 49.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 98.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 49.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 49.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 144.0 For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3 within 7 days prior to enrollment * Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment) 49.0 GENERAL INCLUSION CRITERIA FOR SUBPROTOCOLS: For patients with solid tumors without known bone marrow involvement:* Peripheral absolute neutrophil count (ANC) >= 1000/mm^3* Platelet count >= 100,000/mm^3 (transfusion independent, defined as not receiving platelet transfusions for at least 7 days prior to enrollment 1500.0 Platelet count >= 100,000/ul 729.0 Platelet count > 75,000/uL 253.0 Platelet count >= 100,000/uL 100.0 Platelet count >= 100,000/uL 74.0 Platelet count >= 100,000/uL (transfusion independent) 275.0 Platelet count >= 75,000/uL (transfusion independent) 74.0 CD4 count >= 50 cells/ul 70.0 Platelet count >= 100,000/uL; Note: no transfusions are permitted 7 days prior to laboratory studies to determine eligibility 340.0 Platelet count >= 100,000/uL, obtained within 4 weeks prior to randomization 300.0 Platelet count >= 100,000/uL 400.0 Platelets >= 75,000 cells /uL (unsupported, defined as no platelet transfusion within 7 days) 110.0 INCLUSION CRITERIA FOR STRATUM C: Platelets >= 75,000 cells/uL (unsupported, defined as no platelet transfusion within 7 days) 110.0 Platelet count >= 50,000/uL 44.0 Absolute CD4 count > 200 cells/uL 46.0 Platelet count >= 75,000/uL 337.0 CD4+ T-cell count >= 100 cells/uL 60.0 Platelet count >= 100,000/uL (transfusion independent) 45.0 Platelets >= 100,000/uL (untransfused) 400.0 Platelets >= 100,000 cells/uL (75 x 10^9 L); and, 90.0 Platelets >= 100,000/ul 97.0 Platelets >= 100,000/uL 72.0 Platelets >= 100,000/ul 104.0 TUMOR BIOPSY SEQUENCING: Platelets >= 100,000/uL (mcL) 700.0 TREATMENT: Platelets >= 100,000/uL (mcL) 700.0 Platelets >= 100,000/ul (unsupported) 52.0 Platelets >= 90 x 10^3/uL 92.0 Platelets >= 100,000/uL 23.0 Platelets >= 100,000/ul 280.0 Platelets >= 100,000/ul 450.0 Platelets >= 100,000/ul 96.0 Platelets >= 100,000/uL 58.0 Platelets >= 100,000/uL 35.0 Platelets > 100,000/uL 188.0 Platelets >= 100,000/uL 33.0 Platelets > 100,000/uL 32.0 Platelets >= 100 x 10^3/uL 714.0 Platelets >= 100,000/uL 40.0 Platelets >= 100,000/uL 30.0 Platelets >= 100,000/ul 50.0 Platelet count >= 100,000/mm� 700.0 Platelet (PLTs) count >= 100,000/mm^3 obtained =< 21 days prior to registration 360.0 Platelet count >= 100,000 cells/mcL 155.0 Peripheral platelet count (PLT) >= 75,000/mm^3 48.0 Platelet count >= 100,000/mm^3 1120.0 Platelet count > 100,000 224.0 Platelet count >= 100,000/mL within 28 days prior to registration 1900.0 STEP I: Untransfused platelet count >= 75,000 cells/mm^3 (obtained within 28 days prior to randomization) 1080.0 Platelet count < 100 x 10^9/L 45.0 Platelet count > 100,000/mm^3 2060.0 Platelet count >= 50 x 10^9/L 97.0 Platelet count >= 75,000/mm^3 within 90 days prior to randomization 150.0 Platelet count >= 100,000/mm^3 34.0 Platelet count >= 100,000 mcl obtained within 28 days prior to sub-study registration 10000.0 Platelet count >= 100 x 10^9/L 250.0 Platelet count >= 100 x 10^9/L measured within 28 days prior to randomization 1500.0 Platelet count >= 100,000/mm^3 20.0 Platelet count >= 100,000/mcL 600.0 Patients on Part C with acute lymphoblastic leukemia: platelet count >= 20,000/mm^3 (may receive platelet transfusions); these patients must not be known to be refractory to red cell or platelet transfusion 148.0 Platelet count > 50,000/mm^3 125.0 Platelet count >= 75,000/mm^3 30.0 Platelet count >= 100,000/mm^3 420.0 Within 6 weeks prior to randomization: Platelet count must be >= 100,000/mm^3 990.0 Platelet count >= 100,000/mm^3 195.0 Re-registration: platelet count >= 100,000/mm^3 195.0 Within 14 days of registration: Platelet count >= 75,000/mm^3 110.0 Platelet count >= 100,000/mm^3 69.0 Platelet count >= 100,000/mm^3 130.0 Platelet count >= 100,000/mm^3 45.0 Platelet count >= 75,000/mcL; must be obtained within 28 days prior to registration 180.0 Platelet count >= 100,000/ mL within 21 days prior to registration 333.0 Platelet count >= 100,000/mm^3 137.0 CLINICAL/LABORATORY CRITERIA: Platelet count >= 100,000/mcL; these results must be obtained within 28 days prior to registration 53.0 Platelet count must be >= 100,000/mm^3 within 28 days before randomization 348.0 Platelet count >= 100,000/mm^3, within 4 weeks of randomization 766.0 Platelet count >= 100,000/mm^3 124.0 Platelet count >= 100,000 mm^3; platelets >= 75,000 required for patients who received cycle 1 of mFOLFOX6 prior to registration 700.0 Platelet count < 100 x 10^9/L 98.0 Platelet count >= 75,000/mm^3 324.0 Platelets >= 100,000 cells/mm^3 285.0 Platelets >= 100,000 cells/mm^3 37.0 Platelets >= 70,000 cells/mm^3, within 21 days prior to study entry 143.0 Platelets >= 60,000 cells/mm^3; obtained within 14 days prior to study entry 368.0 Platelets >= 100,000 cells/mm^3 252.0 Platelets >= 100,000 cells/mm^3 660.0 Platelets >= 100,000 cells/mm^3 234.0 Platelets >= 100,000 cells/mm^3 obtained within 30 days prior to registration 330.0 Platelets >= 100,000 cells/mm^3 within 14 days prior to study registration 440.0 Platelets >= 100,000 cells/mm^3, within 21 days prior to registration 924.0 Platelets >= 100,000 cells/mm^3 182.0 Platelets >= 100,000 cells/mm^3 606.0 Platelets >= 50,000 cells/mm^3 360.0 Platelets >= 50,000 cells/mm^3 186.0 Platelets >= 100,000 cells/mm^3 120.0 Platelets >= 100,000/mm^3, equivalent to CTCAE v 3.0 grade 0-1 164.0 Platelets >= 100,000/mm^3 545.0 Within 60 days prior to registration on study: Platelets >= 100,000/mm^3 2580.0 Platelets >= 100,000/mm^3 130.0 Platelets >= 100,000/mm^3 110.0 Platelets >= 100,000/mm^3 52.0 Platelets: >= 75,000/mm^3 within 90 days before enrollment 5058.0 Platelets >= 50,000 /mm^3 84.0 Platelets >= 100,000/mm^3 44.0 Platelets >= 30,000/mm^3 NONE Platelets > 100,000 mm^3, must be obtained within 8 weeks prior to screening for protocol therapy 562.0 Platelets: >= 100,000/mm^3 56.0 Platelets >= 100,000/mm^3 60.0 Platelets >= 100,000/mm^3 126.0 Platelets >= 100,000/mm^3 within 4 weeks prior to randomization 345.0 Platelets >= 100,000/mm^3 36.0 Platelets >= 100,000/mm^3 24.0 Platelets: >= 100,000 / mm^3 56.0 Platelets >= 100,000 cell/mm^3 612.0 Platelets >= 100,000/mcL assessed within seven (7) days prior to the start of therapy 30.0 REGISTRATION #2 - PRIOR TO CONSOLIDATION CHEMOTHERAPY: Platelets >= 100,000/mcl 162.0 Obtained within 30 days of registration: Platelets >= 75,000/mcL or >= 50,000/mcL with documented bone marrow involvement 24.0 Platelets >= 100,000/mcL within 28 days prior to registration 491.0 Obtained =< 7 days prior to registration: Platelets (PLT) >= 100,000/mm^3 102.0 Platelets >= 100,000/L (unsupported), within 14 days of registration and within 7 days of the start of treatment 180.0 Platelets >= 75,000/mcL (75 x 10^9/L) obtained within 2 weeks prior to registration 189.0 Platelets >= 50,000/mcl within 28 days prior to registration 44.0 Registration Step 3 � Maintenance: Patients must have adequate marrow function as evidenced by platelets >= 75,000/mcl within 28 days prior to registration 44.0 Obtained within 28 days prior to registration: Platelets >= 75,000/mcL 223.0 Within 14 days prior to registration: Platelets >= 100,000/mcL 143.0 Platelets greater than or equal to 100,000/mcl, within 14 days prior to registration 147.0 Obtained within 28 days prior to registration: Platelets >= 50,000/mcl 77.0 Platelets >= 100 x 10^9/L within 14 days prior to registration. 186.0 Within 28 days prior to registration: Platelets >= 75,000/mcL 707.0 Within 14 days prior to registration: Platelets >= 100,000/mcl 488.0 Within 28 days prior to administration of study treatment: Platelets >= 100,000/mcL 90.0 Within less than or equal to 14 days prior to registration: Platelets >= 100 x 10^9/L 40.0 Within 28 days prior to administration of therapy: Platelets >= 100,000/mcL 132.0 Platelets >= 100,000/mcL, obtained within 28 days prior to step 2 registration 1000.0 Platelets >= 100,000/mcL within 28 days prior to registration 64.0 Platelets >= 75,000/mcL within 28 days prior to registration 150.0 Platelets >= 100,000/mcL within 28 days prior to registration 94.0 Platelets >= 100 x 10^9/L 72.0 Platelets >= 100 x 10^9/L 30.0 Platelets >= 100 x 10^9/L 40.0 Platelets >= 100 x 10^9/L, within 2 weeks of the first dose of study treatment 18.0 Platelets >= 75 x 10^9/L 68.0 Platelets >= 100 x 10^9/L 130.0 Platelets >= 100 x 10^9/L 35.0 Platelets >= 100 x 10^9/L 18.0 Platelets (Plt) > 100 23.0 Platelets >= 100,000/microliters 37.0 Platelets >= 100 x 10^9/L 36.0 Platelets >= 100 x 10^9/L 64.0 Platelets >= 100 x 10^9/L (transfusion dependent) 25.0 Platelets >= 75 x 10^9/L 68.0 Platelets >= 100,000 x 10^9 /L 21.0 Platelets >= 75 x 10^9/L within 30 days of day 1 of study 27.0