Have a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients or to dimethyl sulfoxide (DMSO) or to either carboplatin or paclitaxel
30.0
TREATMENT: Patients with a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib dimethyl sulfoxide (DMSO), its excipients, or DMSO, are ineligible to receive treatment with trametinib DMSO
700.0
TREATMENT: Patients with a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib DMSO, its excipients, or DMSO, are ineligible to receive treatment with trametinib DMSO
700.0
Known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to the study treatments, their excipients, and/or dimethyl sulfoxide (DMSO)
40.0
Known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to the study treatments, their excipients, and/or dimethyl sulfoxide (DMSO)
18.0
Have a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib or excipients or to dimethyl sulfoxide (DMSO)
68.0
Have a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients or to dimethyl sulfoxide (DMSO), or to compounds of similar chemical or biologic composition to navitoclax
130.0
History of known immediate or delayed hypersensitivity reactions attributed to compounds of similar chemical or biologic composition to AT13387, dabrafenib, or trametinib, or excipients or to dimethyl sulfoxide (DMSO)
32.0
Known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients, or to dimethyl sulfoxide (DMSO), or to Cremophor EL (polyoxyethylated castor oil); please note, exclusion for Cremophor is unnecessary unless paclitaxel is the only agent available and the patient randomizes to the conventional therapy option
250.0
Have a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients or to dimethyl sulfoxide (DMSO) or to thyrotropin alpha (Thyrogen)
35.0
Known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to the study treatments, their excipients, and/or dimethyl sulfoxide (DMSO)
18.0
CLINICAL/LABORATORY CRITERIA: Patients must not have an immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients, or to dimethyl sulfoxide (DMSO) or other agents used in the study
53.0
Have a known immediate or delayed hypersensitivity reaction or idiosyncrasy to drugs chemically related to trametinib, or excipients or to dimethyl sulfoxide (DMSO)
27.0
Patients with known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
23.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
35.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
488.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
72.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
40.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
60.0
No known hypersensitivity to Chinese hamster ovary (CHO) cell products or any component of the atezolizumab formulation
700.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
22.0
Patients with known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
98.0
Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
78.0
Serum Albumin < 2.5 g/dL
45.0
Serum albumin >= 2.8 g/dL
55.0
Albumin >= 3 g/dL, within 14 days of registration and within 7 days of the start of treatment
180.0
Serum albumin >= 2.8 g/dL
42.0
Serum albumin >= 28 g/L
72.0
Serum albumin >= 2.5 g/dL
97.0
Patients must have a serum albumin >= 2.5 g/dL within 28 days prior to registration
97.0
Albumin >= 2.5 g/dL
30.0
Serum albumin >= 2 g/dL
77.0
Albumin >= 2.5 g/dL
40.0
Albumin >= 2.5 g/dL
130.0
Serum albumin >= 2 g/dL
154.0
Albumin >= 2.5 g/dL
250.0
Serum albumin >= 3 g/dL
40.0
Patients on Part A and Part B: serum albumin >= 2 g/dL
148.0
Patients on Part C with ALL: serum albumin >= 2 g/dL
148.0
Albumin >= 2.5 mg/dl
182.0
Albumin >= 2.5 g/dL
35.0
Serum albumin >= 2.5 g/dL
280.0
Serum albumin >= 2.8 g/dL
90.0
Albumin >= 2.5 g/dL
18.0
Serum albumin >= 2.8 g/dL
135.0
Serum albumin >= 2 g/dL
81.0
Albumin >= 2.8 g/dL
96.0
Albumin >= 2 g/dl
110.0
INCLUSION CRITERIA FOR STRATUM C: Albumin >= 2 g/dl
110.0
Serum albumin >= 2 g/dL
67.0
Serum albumin >= 2 g/dL
44.0
Serum albumin >= 3 g/dL
150.0
Within 14 days prior to registration: Serum albumin >= 3.0 g/dL
143.0
Serum albumin >= 2 g/dL
65.0
Serum albumin >= 2 g/dl
36.0
Albumin >= 2 g/dl
25.0
Serum albumin >= 2.8 g/dL
146.0
Serum albumin >= 2 g/dL
51.0
Patients with hypersensitivity to albumin are not eligible
51.0
Albumin >= 2.5 g/dL within 28 days prior to registration
64.0
Albumin >= 2.5 g/dl
186.0
Albumin >= 2.5 g/dL within 30 days of day 1 of study
27.0
Patients with solid tumors: serum albumin >= 2 g/dL
49.0
Serum albumin >= 2 g/dL
98.0
Serum albumin >= 2 g/dL
49.0
Serum albumin >= 2 g/dL
49.0
Serum albumin >= 2 g/dL
144.0
Serum albumin >= 2 g/dL within 7 days prior to enrollment
49.0