subjects study therapy eligible investigator treatment prior receiving chemotherapy opinion participant research study received encephalopathy does treatment cell deficits household receive patients chemotherapy treatment unable planning study eligible therapy plan elapsed weeks therapy prior days radiation chemotherapy completion minimum dose participants research study prior eligible treated treatment received malignancy therapy chemotherapy prior weeks patients treatment systemic dose days regimen study radiation weeks therapy prior study treatment dose enrollment chemotherapy drug previously received patients study subjects therapy untreated treatment radiation participated cgy radiation tbi therapy delivered prior patients centigray ineligible therapeutic radionuclide treatment dose weeks received study subject participant prior yttrium initiating prior treatment therapy days study protocol weeks systemic estrogens received prior therapy patients treatment radiation eligible weeks dose study dose treatment study radiation days therapy received bone metastasis site radiation marrow bone therapy prior received weeks pelvis patients hematopoietically