kinase inhibitor molecule small investigational treatment metabolites compound including receipt 
jak inhibitor janus kinase prior ruxolitinib therapy inhibitors treatment received 
inhibitor prior treatment hsp therapy received hdac kinase previous met 
cdk inhibitor prior treatment received therapy patient inhibitors patients previous 
valproic acid deacetylase hdac histone panobinostat prior patients treatment need 
cdk cyclin dependent kinase inhibitor prior treatment received therapy previously