confirmed histologically cytologically diagnosis metastatic patients melanoma cancer pathologically carcinoma 
pancreatic adenocarcinoma histologically confirmed cytologically metastatic ductal advanced diagnosis patients 
exist longer measures curative standard effective palliative unresectable histologically confirmed 
colorectal histologically confirmed cytologically metastatic adenocarcinoma cancer unresectable diagnosis patients 
mesothelioma pleural malignant peritoneal histologically mpm confirmed pemetrexed cytologically unresectable